Mitotic chromatin marking governs the segregation of DNA damage by Juliette Ferrand, Juliette Dabin, Odile Chevallier, Matteo Kane-Charvin, Ariana Kupai, Joel Hrit, Scott B. Rothbart, Sophie E. Polo

“…We propose that this mechanism may help preserve the integrity of stem cell compartments during asymmetric cell divisions.…”
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The Management of Classical Hodgkin's Lymphoma: Past, Present, and Future by S. E. Richardson, C. McNamara

“…Even in relapse, CHL patients can be salvaged with high dose chemotherapy and autologous haematopoietic stem cell transplantation (ASCT). Challenges remain, however, in finding new strategies to manage the small number of patients who continue to relapse or progress. …”
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A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer by Xiao Yi Yang, Li Hua Wang, William L. Farrar

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Immediate Response to Chemotherapy in an Adult Neuroblastoma Patient Presenting with Cord Compression by Nedal Bukhari, Bachar Harfouch, Majid Shallal Alotaibi, Hulayel Al-Harbi, Omar Chamdine

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Protocol to image, segment, and quantify cortical contractions in maturing mouse oocytes by Gaëlle Letort, Elvira Nikalayevich

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A CD26+ tendon stem progenitor cell population contributes to tendon repair and heterotopic ossification by Siwen Chen, Yingxin Lin, Hao Yang, Zihao Li, Sifang Li, Dongying Chen, Wenjun Hao, Shuai Zhang, Hua Chao, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Hui Liu

“…Here we identify a CD26+ tendon stem/progenitor cells residing in peritendon, which constitutes a primitive stem cell population with self-renewal and multipotent differentiation potentials. …”
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Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair by Yacine Kharraz, Joana Guerra, Christopher J. Mann, Antonio L. Serrano, Pura Muñoz-Cánoves

“…We describe how ordered changes in macrophage polarization, from M1 to M2 subtypes, can differently affect muscle stem cell (satellite cell) functions. Finally, we also highlight some of the new mechanisms underlying macrophage plasticity and briefly discuss the emerging implications of lymphocytes and other inflammatory cell types in normal versus pathological muscle repair.…”
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Vitreous Mediators in Retinal Hypoxic Diseases by Roberto dell'Omo, Francesco Semeraro, Giulio Bamonte, Francesco Cifariello, Mario R. Romano, Ciro Costagliola

“…Cytokines and chemokines are multifunctional mediators that can direct the recruitment of leukocytes to sites of inflammation, promote the process, enhance immune responses, and promote stem cell survival, development, and homeostasis. The modern particle-based flow cytometric analysis is more direct, stable and sensitive than the colorimetric readout of the conventional ELISA but, similar to ELISA, is influenced by vitreous hemorrhage, disruption of the blood-retina barrier, and high serum levels of a specific protein. …”
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Complex Variant of Philadelphia Translocation Involving Chromosomes 9, 12, and 22 in a Case with Chronic Myeloid Leukaemia by F. Malvestiti, C. Agrati, S. Chinetti, A. Di Meco, S. Cirrincione, M. Oggionni, B. Grimi, F. Maggi, G. Simoni, F. R. Grati

“…Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder included in the broader diagnostic category of myeloproliferative neoplasms, associated with fusion by BCR gene at chromosome 22q11 to ABL1 gene at chromosome 9q34 with the formation of the Philadelphia (Ph) chromosome. …”
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Imaging cell spheroid clusters: An MRI protocol for non-invasive standardized characterization by Rebecca Wißmann, Petros Martirosian, Marina Danalache, Gerd Grözinger, Fritz Schick, Stefanie Elser

“…Despite its limited spatial resolution, this method adeptly reveals information about the composition and vitality of stem cell and cancer spheroids and their micro-environment in a non-invasive manner. …”
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The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness by Kristina Narfström, Koren Holland Deckman, Marilyn Menotti-Raymond

“…Therapeutic trials have been performed mainly in the former type including stem cell therapy, retinal transplantation, and development of ocular prosthetics. …”
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Spinal Fusion in the Next Generation: Gene and Cell Therapy Approaches by Marta Barba, Claudia Cicione, Camilla Bernardini, Vincenzo Campana, Ernesto Pagano, Fabrizio Michetti, Giandomenico Logroscino, Wanda Lattanzi

“…The improved knowledge of both mesenchymal stem cell biology and osteogenic molecules allowed their use in regenerative medicine, representing attractive approaches to achieve bone regeneration also in spinal surgery applications. …”
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Severe Combined Immunodeficiency Disorder due to a Novel Mutation in Recombination Activation Gene 2: About 2 Cases by Ibtihal Benhsaien, Fatima Ailal, Khadija Elazhary, Jalila El bakkouri, Abdallah Badou, Ahmed Aziz Bousfiha

“…Affected children are highly susceptible to bacterial, viral, fungal, and opportunistic infections with life-threatening in the absence of hematopoietic stem cell transplantation. We report here two cases of SCID. …”
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Myelodysplastic Syndrome with Transfusion Dependence Treated with Venetoclax by Waqas Jehangir, Alexander Karabachev, Taimoor Jahangir, Elvira Umyarova

“…They are a group of heterogeneous clonal stem cell malignancies with a high risk to progress to acute myeloid leukemia. …”
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Plasma Cell Leukemia: A Review of 3 Cases Managed in Kenya by Matilda Ong’ondi, Elizabeth Kagotho

“…Treatment with novel agents followed by autologous stem cell transplant in those who are transplant eligible leads to better outcomes.…”
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A platform for Bioengineering Tissue Membranes from cell spheroids by Quang Bach Le, Hariharan Ezhilarasu, Weng Wan Chan, Alok Tanala Patra, Priya Murugan, Shashaank Abhinav Venkatesh, Yean Kai Tay, Shin Ru Lim, Ahmad Amirul Abdul Rahim, Jia Sheng Zach Lee, Xuezhi Bi, Deepak Choudhury

“…We demonstrated this method by producing cartilage tissue membranes from human mesenchymal stem cell spheroids undergoing chondrogenic differentiation, evaluating spheroid sizes, assembly timing, fusion process and membrane thickness. …”
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The Interplay between the Bone and the Immune System by Giorgio Mori, Patrizia D'Amelio, Roberta Faccio, Giacomina Brunetti

“…On the other hand, osteoblasts, the bone-forming cells, regulate hematopoietic stem cell niches from which all blood and immune cells are derived. …”
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OUTPOST: A comprehensive analysis software for whole‐metagenome shotgun sequencing incorporating group stratification by Yihang Zhou, Jihong Zheng, Wenqi Song, Xinyi Yan, Li Du, Zhonglin Ma, Yanbin Fu, Zhaohui Ouyang, Yuchen Xiao, Zhuoqun Liu, Feng Tian, Jason Wing Hon Wong, Jen Hao David Shih, Shikang Liang, Honglei Tian, Liu Liu, Ke Wei, Chao Zhang, Jiangtao Li, Xiaozhu Wang

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Interleukin 15‐Presenting Nanovesicles with Doxorubicin‐Loaded Ferritin Cores for Cancer Immunochemotherapy by Yihui Zhai, Wen Zhang, Jinming Wang, Ying Kong, Rong Rong, Tianqun Lang, Chao Zheng, Yanke Wang, Yang Yu, Helen He Zhu, Ying Cai, Pengcheng Zhang, Yaping Li

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Reduction of elevated Gli3 does not alter the progression of autosomal recessive polycystic kidney disease by Lauren G. Russell, Maria Kolatsi‐Joannou, Laura Wilson, Jennifer C. Chandler, Nuria Perretta Tejedor, Georgie Stagg, Karen L. Price, Christopher J. Rowan, Tessa Crompton, Norman D. Rosenblum, Paul J. D. Winyard, David A. Long

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