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2581
Fractional-Order PI Control of First Order Plants with Guaranteed Time Specifications
Published 2013-01-01“…Whether or not CDCs are superior to purified populations, for example, c-kit+ cardiac stem cells, or to gene therapy approaches for cardiac regeneration remains to be evaluated.…”
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2582
“TRANSHUMANIZATION” OF MODERN EDUCATION
Published 2018-02-01“…NBICS combine nanotechnology, biotechnology, IT, cognitive and social sciences, genetic engineering, stem cells, and cloning. These research areas converge and create a cumulative effect. …”
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2583
Revolution of blood cancer treatment in the oral cavity: Breakthroughs in nanotherapy
Published 2024-09-01“…Nanotherapy has also been investigated for overcoming drug resistance, targeting cancer stem cells, bypassing efflux pumps, and gene silencing. …”
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2584
Recent Advances in DNA Systems for In Situ Telomerase Activity Detection and Imaging
Published 2025-01-01“…Its activity is pivotal in stem cells and cancer cells but absent in most normal somatic cells. …”
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2585
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder
Published 2024-04-01“…This was parallel to laboratory molecular investigations of in vitro GABAergic neurons derived from induced human pluripotent stem cells (hiPSCs) of SSADHD subjects and biochemical analyses performed on a versatile murine model that uses an inducible and reversible rescue strategy allowing on-demand and cell-specific gene therapy. …”
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2586
Transcriptional role of androgen receptor in the expression of long non-coding RNA Sox2OT in neurogenesis.
Published 2017-01-01“…We identified a new DNA binding region upstream of Sox2 locus containing three androgen response elements (ARE), and found that AR binds such a sequence in embryonic neural stem cells and in mouse embryonic brain. Our data suggest that through this binding, AR can promote the RNA polymerase II dependent transcription of Sox2OT. …”
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2587
The Relevance and Potential Role of Orbital Fat in Inflammatory Orbital Diseases: Implications for Diagnosis and Treatment
Published 2024-12-01“…This review also explores the characteristics and potential applications of orbital fat-derived stem cells, with an emphasis on their regenerative abilities and anti-inflammatory effects. …”
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2588
Interplay between Inflammation and Stemness in Cancer Cells: The Role of Toll-Like Receptor Signaling
Published 2016-01-01“…Cancer stem cells (CSCs) are a small population of cancer cells that exhibit stemness. …”
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2589
The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development
Published 2025-01-01“…PER2/3, as antagonists in cancer stem cell biology, play important roles in differentiating cancer stem cells and in maintaining their stemness. …”
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2590
Phytonanoparticles as novel drug carriers for enhanced osteogenesis and osseointegration
Published 2025-01-01“…Looking ahead, we identify key research directions, including developing personalized therapies, combination approaches with stem cells or gene delivery, and long-term safety assessments. …”
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2591
The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB)
Published 2024-06-01“…Additionally, we explore dysfunction in aging stem cells, hepatocytes, and cardiomyocytes.…”
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2592
Role of Extracellular Vesicles in Placental Inflammation and Local Immune Balance
Published 2021-01-01“…Various types of cells, such as trophoblasts, endothelial cells, immune cells, mesenchymal stem cells (MSCs), and adipocytes, mediate cell-to-cell interactions through soluble factors to maintain normal placental development. …”
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2593
Postcare for Repairing Nerve and Tendon Injury Based on Biomimetic Nano-Parallel Material Composite Protein
Published 2022-01-01“…The purpose of this study is to study the use of biomimetic nano-parallel material composite proteins to induce the directional differentiation of stem cells to tendon lineages to promote muscle regeneration and repair. …”
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2594
MiRNA-223-5p inhibits hypoxia-induced apoptosis of BMSCs and promotes repair in Legg-Calvé-Perthes disease by targeting CHAC2 and activating the Wnt/β-catenin signaling pathway.
Published 2025-01-01“…This study investigates the role of miRNA-223-5p in regulating hypoxia-induced apoptosis and enhancing osteogenesis in bone marrow mesenchymal stem cells (BMSCs). Utilizing a juvenile New Zealand white rabbit model of LCPD established through femoral neck ligation, we transfected BMSCs with miR-223-5p mimics, inhibitors, and controls, followed by hypoxic exposure. …”
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2595
Regeneration in the absence of canonical neoblasts in an early branching flatworm
Published 2025-01-01“…Abstract The remarkable regenerative abilities of flatworms are closely linked to neoblasts – adult pluripotent stem cells that are the only division-competent cell type outside of the reproductive system. …”
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2596
Circular RNAs as a novel class of potential therapeutic and diagnostic biomarkers in reproductive biology/diseases
Published 2024-12-01“…CircRNAs are integral pieces in multiple cellular functions, including moving substances within the nucleus, silencing one X chromosome, cell death, the ability of stem cells to differentiate into different cell types, and the process of gene expression inherited from parental genes. …”
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2597
Strategies to Overcome Intrinsic and Acquired Resistance to Chemoradiotherapy in Head and Neck Cancer
Published 2024-12-01“…In this review, we will discuss how overexpression of efflux pumps, perturbation of apoptosis-related factors, increased expression of antioxidants, glucose metabolism, metallotheionein expression, increased DNA repair, cancer stem cells, epithelial-mesenchymal transition, non-coding RNA and the tumour microenvironment contribute towards resistance of HNC to chemotherapy and/or radiotherapy. …”
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2598
How does the tea L-theanine buffer stress and anxiety
Published 2022-05-01“…This review focuses on the relaxation effect of L-theanine, including animal models and the latest human trials as well as the potential molecular mechanisms regarding neuron stem cells. The biological efficacy of dietary L-theanine in the food matrix has been further discussed in this review in relation to the physiological changes in the gastrointestinal tract and bindings of L-theanine with other food components.…”
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2599
Effect of amniotic fluid on hair follicle growth
Published 2025-12-01“…Purpose: Human amniotic fluid stem cells (hAFSCs) have shown significant regenerative potential in treating hair loss, wound healing, and tissue repair. …”
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2600
Effects of Pentoxifylline in a Rat Model of Manganism: Evaluation of the Possible Toxicity
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