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2441
NLRP7 maintains the genomic stability during early human embryogenesis via mediating alternative splicing
Published 2025-01-01“…Here, we show that NLRP7 knockout affects the genetic stability, resulting in increased DNA damage in both human embryonic stem cells and blastoids, making embryonic cells in blastoids more susceptible to apoptosis. …”
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2442
The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review
Published 2010-01-01“…Stem cells also interact with the chemoattractants C3a, C5a, SDF-1, and thrombin to promote stem cell migration into damaged tissue to support tissue homeostasis.…”
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2443
Mitochondrial apoptosis in response to cardiac ischemia-reperfusion injury
Published 2025-01-01“…The death of each cell (cardiomyocytes, endothelial cells, vascular smooth muscle cells, cardiac fibroblasts, and mesenchymal stem cells) after myocardial ischemia/reperfusion is associated with apoptosis due to mitochondrial dysfunction. …”
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2444
Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report
Published 2025-01-01“…From May 2021 to November 2022, she received allogeneic Umbilical cord mesenchymal stem cells (UCMSC) therapy (5.0 × 107 UCMSCs per time, totaling 10 infusions), but her condition did not improve. …”
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2445
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2446
Osteodifferentiation of Human Preadipocytes Induced by Strontium Released from Hydrogels
Published 2012-01-01“…The application of stem cells together with biomaterials releasing bioactive factors promotes the formation of bone tissue by inducing proliferation and/or cell differentiation. …”
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2447
Performance of PRP Associated with Porous Chitosan as a Composite Scaffold for Regenerative Medicine
Published 2015-01-01“…This study aimed to evaluate the in vitro performance of activated platelet-rich plasma associated with porous sponges of chitosan as a composite scaffold for proliferation and osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells. The sponges were prepared by controlled freezing (−20, −80, or −196°C) and lyophilization of chitosan solutions (1, 2, or 3% w/v). …”
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2448
MANAGEMENT OF A RARE CASE OF PEDIATRIC DEEP STERNAL WOUND INFECTION WITH VACUUM-ASSISTED CLOSURE (VAC)
Published 2022-12-01“…Growth factors and stem cells in nano fat complemented the micro fat properties, thus increasing the survivability rate. …”
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2449
Research progress on platelets in glioma
Published 2025-01-01“…Apart from the intrinsically indestructible characteristics of glioma (stem) cells, accumulating evidence suggests that the tumor microenvironment also plays a vital role in the refractoriness of glioblastoma. …”
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2450
Novel one-step lignin microsphere preparation for oral tissue regeneration applications
Published 2025-01-01“…In vitro biomedical tests further revealed that the LMSs at concentrations <25 μg/mL had good biocompatibility toward gingival mesenchymal stem cells (GMSCs) and jaw bone marrow mesenchymal stem cells (JBMMSCs), with a low apoptosis rate, outperforming other lignin materials. …”
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2451
Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma
Published 2013-01-01“…Objective. The intrahepatic stem cells, also known as hepatic progenitor cells (HPCs), are able to differentiate into hepatocytes and bile duct epithelia. …”
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2452
Role of Leucine-Rich Repeat–Containing G-Protein-Coupled Receptors 4–6 (LGR4–6) in the Ovary and Other Female Reproductive Organs: A Literature Review
Published 2025-01-01“…LGR6 is a marker for fallopian tube stem cells and is involved in stem cell maintenance and differentiation. …”
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2453
Posttransplantation Lymphoproliferative Disease Treated by Retransplantation
Published 2020-01-01“…We describe our strategy to meet the patient’s urgent need for EBV-specific T cells, as well as new hematopoietic stem cells. The same donor was used for a second transplant, using peripheral blood stem cells. …”
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2454
Exploring the Active Constituents of <i>Andrographis paniculata</i> in Protecting the Skin Barrier and the Synergistic Effects with Collagen XVII
Published 2025-01-01“…Furthermore, the protective effects of AHE and its active ingredients on UVB-damaged epidermal stem cells were investigated. Notably, the combined treatment with andrographolide and collagen XVII enhanced the viability of UVB-damaged epidermal stem cells, increased the expression of stemness markers integrin β1 and p63, and decreased the expression of the differentiation marker keratin 10. …”
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2456
Advances in the Development and Application of Human Organoids: Techniques, Applications, and Future Perspectives
Published 2025-01-01“…Organoids are three-dimensional (3D) cell cultures derived from human pluripotent stem cells or adult stem cells that recapitulate the cellular heterogeneity, structure, and function of human organs. …”
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2458
Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies
Published 2022-01-01“…On the other hand, mesenchymal stem cells (MSC) have experimentally demonstrated fibrosis regression effects, but it is necessary to have an animal model of advanced liver fibrosis to evaluate the effect of these cells. …”
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2459
Lyophilized powder of calf bone marrow hydrolysate liposomes improved renal anemia: In vitro and in vivo evaluation.
Published 2024-01-01“…Its hematopoietic ability was proved by the colony formation experiment of umbilical cord blood hematopoietic stem cells in vitro. The rat model of renal anemia was established by adenine intragastric administration, and different concentrations of CBMHL were intragastricly administrated. …”
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2460
Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson’s Disease
Published 2025-01-01“…Using a sandwich ELISA, we compared cystatin C concentration in blood derivatives (plasma and serum) and culture media of derived models (stem cells, neuroepithelial stem cells, and midbrain organoids) of three idiopathic Parkinson’s disease and three age-matched healthy control subjects with the same CST3 genotype. …”
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