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981
Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators
Published 2025-01-01“…A gene expression signature that is characteristic of CD4+ cytotoxic T lymphocytes (CD4-CTLs) was found to be elevated at baseline in non-responders to apheresis, although this could not be validated with statistical significance (n=19 MS patients).ConclusionOur data reveal that therapeutic apheresis in MS rapidly leads to a significant decrease in IgG reactivities against EBNA1 (391-410) and cross-reactive targets such as GlialCAM (370-389) and also has an impact on the gene expression of B cells and T cells. …”
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982
Salivary Cortisol Determination in ACTH Stimulation Test to Diagnose Adrenal Insufficiency in Patients with Liver Cirrhosis
Published 2019-01-01“…The prevalence of AI in cirrhotic patients was higher when determined by TSC (48.7%) than by SaC (30.8%); however, this difference did not reach statistical significance. AI was associated with sex, cirrhosis etiology, and Child-Pugh classification. …”
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983
Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah...
Published 2025-02-01“…Data were analyzed using SPSS, with chi-square and logistic regression identifying risk factors. Statistical significance was determined at a threshold of p < 0.05. …”
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984
The effect of the number of endometrial CD138+ cells on the pregnancy outcomes of infertile patients in the proliferative phase
Published 2025-01-01“…Although the 0 and ≥3 positive lesions groups showed a trend toward higher rates of clinical pregnancy (P =0.132), these differences failed to reach statistical significance. After age, body mass index (BMI), and clinical features were adjusted for, the ≥3 positive lesions group showed significantly lower live birth rates (aOR, 1.84; 95%CI, 1.08-3.15; P =0.026), clinical pregnancy (adjusted odds ratio (aOR), 1.78; 95% CI, 1.06-2.95; P =0.028), and ongoing pregnancy (aOR, 1.85; 95% CI, 1.09-3.15; P =0.024). …”
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985
ATClean: A Novel Method for Detecting Low-luminosity Transients and Application to Pre-explosion Counterparts from SN 2023ixf
Published 2025-01-01“…Our method “ATLAS Clean,” or ATClean, utilizes the reported fluxes, uncertainties, and fits to the point-spread function (PSF) from difference images to quantify the statistical significance of individual measurements. We apply this method to control light curves across the image to determine whether any source of flux is present in the data for a range of specific timescales. …”
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986
Prevención de eventos trombóticos en pacientes sometidos a cirugía de artrodesis lumbar por vía posterior: experiencia en nuestro centro. Estudio retrospectivo de casos
Published 2025-01-01“…None of the variables studied had statistical significance for the occurrence of a thrombotic event. …”
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987
Clinical expression of facioscapulohumeral muscular dystrophy in carriers of 1–3 D4Z4 reduced alleles: experience of the FSHD Italian National Registry
Published 2016-01-01“…Comparison of the disease severity outcome between index cases with age at onset before and over 10 years of age, failed to detect statistical significance (Wald test p value=0.064). Of 61 index cases, only 17 (27.9%) presented extra-muscular conditions. …”
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988
Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial
Published 2025-01-01“…Compared to the placebo group, there was a statistically significant reduction (p < 0.021) in TLC (mL) after 26 weeks for JBOL. …”
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989
[Translated article] Thrombotic event prevention in patients undergoing posterior lumbar arthrodesis: Our experience. A retrospective case series study
Published 2025-01-01“…None of the variables studied had statistical significance for the occurrence of a thrombotic event. …”
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990
Evaluation of the adherence of municipalities and states to the Ministry of Health’s microplanning for high-quality vaccination activities and the increase in vaccination coverage...
Published 2025-01-01“…In states with full adherence to the OM, most municipalities achieved the VC targets for all evaluated vaccines in 2023, showing statistical significance for pentavalent (D3), polio (D3), and 10-valent pneumococcal (D2) vaccines. …”
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991
Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment
Published 2025-02-01“…However, there were discrepancies in the statistical significance of the results between the propensity score matching and stabilized inverse probability of treatment weighting analysis. …”
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992
Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts
Published 2025-02-01“…Results: Using quantile g-computation, we observed overall null associations between the chemical biomarker mixture and cognitive outcomes among preschool-age children. Although statistical significance was not attained for child sex as an effect modifier, our stratified analysis unveiled a moderate divergence in association trends. …”
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993
Characteristics of cardiopulmonary exercise capacity in adults with different degrees of obesity
Published 2025-01-01“…Spearman correlation analysis was used to analyze the correlation between BMI and various indicators.ResultsThere was no statistical significance in gender composition, age, height, and exercise habit of the five groups of participants (P > 0.05). …”
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994
Prevalence and determinants of intimate partner violence in pregnancy: a multicentre, binational study
Published 2025-02-01“…The level of statistical significance was set at a p-value of < 0.05. Results The prevalence of IPV was 26.2%. …”
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995
Group B streptococcus colonization in pregnancy and neonatal outcomes: a three-year monocentric retrospective study during and after the COVID-19 pandemic
Published 2024-09-01“…Moreover, significant EOD incidence rates have been reported among children of mothers carrying risk factors, although also in this case no statistically significant differences have been observed during and after the pandemic. …”
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996
Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology
Published 2025-02-01“…For the blue tit analyses, the average effect was convincingly negative, with less growth for nestlings living with more siblings, but there was near continuous variation in effect size from large negative effects to effects near zero, and even effects crossing the traditional threshold of statistical significance in the opposite direction. In contrast, the average relationship between grass cover and Eucalyptus seedling number was only slightly negative and not convincingly different from zero, and most effects ranged from weakly negative to weakly positive, with about a third of effects crossing the traditional threshold of significance in one direction or the other. …”
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997
Investigation of Success Levels of Visual Arts Students in Computer-Aided Design Course
Published 2024-06-01“…However, the observed difference in other demographic variables is not statistically significant.…”
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998
Jinkui Shenqi Pill Combined with Pelvic Floor Biofeedback in Treatment of Postpartum Stress Urinary Incontinence with Kidney-yang Deficiency
Published 2021-06-01“…The pelvic floor muscle myoelectric potential was measured before and after treatment, the urine leakage volume in 1h urine pad test, the Short Form of International Consultation on Incontinence Questionnaire(ICI-Q-SF)scores, calculate the total effective rate and follow up the severity of stress urinary incontinence and ICI-Q-SF questionnaire scores were measured six months after treatment.Results:1) After treatment, the typeⅡmyoelectric potential, typeⅠmyoelectric potential, and typeⅠmuscle endurance potential of the two groups were higher than those before treatment, the difference was statistically significant(<italic>P</italic><0.05), and the treatment group was higher than the control group, the difference was statistically significant(<italic>P</italic><0.05).2)The volume of urine leakage in 1 h pad test of the two groups after treatment was less than that before treatment, the difference was statistically significant(<italic>P</italic><0.05), and the treatment group was significantly less than the control group, the difference was statistically significant(<italic>P</italic><0.05).3)The ICI-Q-SF questionnaire scores of the two groups after treatment were lower than those before treatment, the differences were statistically significant(<italic>P</italic><0.05), and the treatment group was significantly lower than the control group, the difference was statistically significant(<italic>P</italic><0.05).4) The total effective rate of the treatment group(88.60%)was higher than that of the control group(65.80%), the difference was statistically significant(<italic>P</italic><0.05).5)Follow-up six months later, the degree of stress urinary incontinence and ICI-Q-SF questionnaire scores of the treatment group were lower than those of the control group, and the differences were statistically significant(<italic>P</italic><0.05).Conclusion:1) Jinkui Shenqi pill combined with pelvic floor biofeedback could enhance the muscle strength of pelvic floor typeⅠand typeⅡmuscles in patients with postpartum stress urinary incontinence with kidney-yang deficiency, improve pelvic floor function recovery, reduce urine leakage, and improve patients'short-term and long-term quality of life, the treatment effect was significant and lasting, and was more effective than pure pelvic floor biofeedback therapy alone;2)The mechanism of Jinkui Shenqi pill in treating postpartum stress urinary incontinence with kidney-yang deficiency may be related to the increase of pelvic floor muscle potential.…”
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999
Angiogenesis Regulated by Electroacupuncture Combined with Rehabilitation Training in Cerebral Ischemia Involved in PI3K/Akt Signaling Pathway
Published 2020-10-01“…The expression of protein in the combined acupuncture group was higher than that of the other two groups, and the difference was statistically significant respectively (<italic>P</italic>< 0.01); the trend of each variable at different time points was significantly different respectively (<italic>F</italic><sub>Time</sub>=100.462, 53.714, 106.552, 75.381, <italic>P</italic>< 0.001), the expression of VEGF and Akt protein in the model group increased on the 7th day, and the difference was statistically significant compared with 3 d and 14 d respectively (<italic>P</italic>< 0.05); the expression of BDNF and PI3K increased on the 7th day in the model group, compared with that on the 3rd day, the difference was statistically significant (<italic>P</italic>< 0.01); the expression of VEGF, BDNF, PI3K, Akt protein increased significantly on the 14th day of the combined acupuncture group, and the difference was statistically significant compared with 3 d and 7 d respectively (<italic>P</italic>< 0.05); The expression group×time all had a significant interaction (<italic>P</italic>< 0.001). (4) The analysis of variance of repeated measurements of VEGF, BDNF, PI3K, Akt mRNA in rat brain tissues in ischemic area showed that the variables were statistically significant in different groups respectively (<italic>F</italic><sub>Intergroup</sub>=445.845, 427.743, 918.388, 543.814, <italic>P</italic>< 0.001), the combined acupuncture group expression was higher than the other two groups, the difference was statistically significant respectively (<italic>P</italic>< 0.01); the change trend of each variable at different time points was significantly different (<italic>F</italic><sub>Time</sub>=100.343, 13.984, 9.162, 32.931, <italic>P</italic>< 0.001), the expression of BDNF and PI3K mRNA in the model group increased on the 7th day, and the difference was statistically significant respectively (<italic>P</italic>< 0.05, <italic>P</italic>< 0.01); the expression of VEGF mRNA in the model group increased on the 7th day, compared with that on the 14th day, the difference was statistically significant (<italic>P</italic>< 0.01); the expression of VEGF, BDNF, PI3K, Akt mRNA increased significantly on the 7th day in the combined acupuncture group, and the difference was statistically significant compared with 3 d and 14 d respectively (<italic>P</italic>< 0.05, <italic>P</italic>< 0.01); the mRNA expression group×time had significant interaction (<italic>P</italic>< 0.001).Conclusion:Under the influence of intervention effect, time effect and the interaction of the two, the combination of electroacupuncture and rehabilitation training can play a protective role in cerebral ischemia, which may be related to the control of the expression of VEGF and BDNF and the downstream transduction pathway PI3K/Akt, which mediates the angiogenesis after cerebral ischemia.…”
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1000
A Comparative Study of Health Efficacy Indicators in Subjects with T2DM Applying Power Cycling to 12 Weeks of Low-Volume High-Intensity Interval Training and Moderate-Intensity Con...
Published 2022-01-01“…The weight index of the MICT intervention showed statistically significant within-group differences (difference=3.52, 95% CI=2.11–4.92, p=0.001<0.01); group differences for the MICT and CON groups were also statistically significant (difference=3.52±2.09, Cd1=−0.39±1.25, p=0.004<0.01). …”
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