Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins by E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A.  D.  Gavrilenko, T.  V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko

“…The ANDSystem software package was used to reconstruct and evaluate the statistical significance of the pathways HCV could potentially use to regulate 32 hypermethylated genes in HCC, including both oncosuppressor and protumorigenic ones identified by genome-wide analysis of DNA methylation. …”
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Clinical Rehabilitation Effect of Postoperative Lower-Limb Training on the Patients Undergoing OLIF Surgery: A Retrospective Study by Haoming Wang, Yachong Huo, Yachao Zhao, Botong Zhang, Dalong Yang, Sidong Yang, Wenyuan Ding

“…The median age of the participants was 57 years (39∼73) in the intervention group and 54 years (35∼71) in the control group. No statistical significance between the two groups was found (P>0.05). …”
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Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head by Peng Zhang, Qing-He Ye, Wen-Xiu Zhu, Yong-Heng Zhao, Hong-Xun Zhu, Biao-Fang Wei

“…The mRNA and protein levels of CHOP and GRP78 were elevated in necrotic area compared to the non-necrotic area of ONFH patients and the FH tissues of FNF patients with statistical significance. The expression levels of CHOP and GRP78 within the local tissues were significantly elevated in patients at FICAT stage 4 as opposed to those at stage 3. …”
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New compounds with a dihydropyridine framework as promising hypolipidemic and hepatoprotective agents by Elena S. Ketova, Anna V. Myazina, Elena Yu. Bibik, Sergey G. Krivokolysko

“…When processing the experimental data, the average arithmetic (AA) was determined. The statistical significance of the compared options was determined on the basis of the Student’s t-test, with the critical value of the Student’s t-test equal to 2.101 and the significance level α = 0.05. …”
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Newborn birth weight and its associated risk factors in Somalia using Somalia health and demographic survey by Denekew Bitew Belay, Nigussie Adam Birhan, Mahad Ibrahim Ali, Ding-Geng Chen

“…The analysis was carried out using ordinal logistic regression and adjusted odds ratio with 95 % confidence interval and p-value <0.05 was used to declare statistical significance. Results: From the total of 7462 newborns include in the study, 1196 (16.03 %), 5304(71.08 %) and 962 (12.89 %) were born with low birth weight, normal birth weight and high birth weight, respectively. …”
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Socioeconomic factors and sex effects of postpartum maternal depression on offspring internalizing symptoms: a systematic review and meta-analysis by Yang Geng, Wenlan Liu, Zhiying Yu, Hui Zhang, Yun Li, Weihua Zhao

“…After adjusting for socioeconomic factors, early nonconcurrent recurrence of postpartum depression was associated with greater odds of internalizing symptoms among adolescent girls than among boys (β = 0.03, 95% CI, 0.01–0.06); however, there was no statistical significance after adjusting for prenatal depression. …”
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Comparing clinical only and combined clinical laboratory models for ECPR outcomes in refractory cardiac arrest by Chun-Chieh Chiu, Yu-Jun Chang, Chun-Wen Chiu, Ying-Chen Chen, Yung-Kun Hsieh, Shun-Wen Hsiao, Hsu-Heng Yen, Fu-Yuan Siao

“…Survivors had similar underlying diseases and younger age without statistical significance (57.0 vs. 61.0 years, p = 0.117). …”
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Bacterial etiologies, antimicrobial susceptibility profiles and associated factors among patients with otitis media referred to Nekemte Public Health Research and Referral Laborato... by Endalu Tesfaye Guteta, Fedasan Alemu Abdi, Seifu Gizaw Feyisa, Betrearon Sileshi Kinfu, Tadese Bekele Tafesse

“…Adjusted odds ratio was used to determine strength of association. Statistical significance was obtained at p-value of below 0.05. …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…We gathered demographic and clinical data, calculated UHR, and explored its correlation with DR development.Outcomes: Individuals diagnosed with diabetic retinopathy (DR) exhibited a markedly elevated uric acid to high-density lipoprotein cholesterol (UHR) ratio when contrasted with those without DR (NDR), achieving statistical significance with a P-value below 0.001. The Mantel-Haenszel chi-square test for linear association validated a pronounced positive correlation between the UHR ratio and the incidence of DR (P< 0.001). …”
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The Influence of Posterior Class II Composite Restoration Location and Techniques on Marginal Sealing by Mishel Haddad, Diva Lugassy, Mohana Barhum, Tamar Brosh, Shlomo Matalon

“…The Kruskal–Wallis test was used to compare the mean gaps among the four quadrants. The statistical significance was set at <i>p</i> = 0.05. <b>Results</b>: No significant difference in the gaps between the Pre-cure and Co-cure techniques was found (<i>p</i> = 0.212). …”
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Anemia in pregnancy: a systematic review and meta-analysis of prevalence, determinants, and health impacts in Egypt by Ahmed Azzam, Heba Khaled, Alrefaey K. Alrefaey, Amar Basil, Sarah Ibrahim, Mohamed S. Elsayed, Muhammad Khattab, Nashwa Nabil, Esraa Abdalwanees, Hala Waheed Abdel Halim

“…The determinants of anemia among pregnant women included being over 30 years old (OR: 1.95), residing in rural areas (OR: 1.76), illiteracy (OR: 1.93), birth spacing < 2 years (OR: 2.04), lack of iron supplementation (OR: 2.59), presence of intestinal parasites (OR: 1.38), antenatal visits < 5 (OR: 5.27), multiparity, and low income, all with statistical significance (p < 0.05). Regarding dietary determinants, a low intake of meat, vegetables, fruits, and high tea consumption was consistently associated with a higher risk of anemia. …”
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Clinical Outcome and Quality of Life after Modular Reverse Total Shoulder Arthroplasty in Comparison with Joint‐Preserving Locking Plate Osteosynthesis in Aged Patients: A Retrospe... by Carina Jaekel, Lisa Oezel, Franziska Leibnitz, Lena Marie Wilms, Joachim Windolf, Sebastian Viktor Gehrmann, Armin Olaf Scholz

“…For statistical analyses, Student's t‐test, Wilcoxon test, and Chi‐Quadrat test were used. Statistical significance was indicated with p < 0.05. Results Totally 34 patients with an average age of 76.6 years were included. …”
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The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients by Zhen-Hao Yu, Gui-Xiang Tian, Yao-Dong Wang, Ting-Yan Liu, Peng Shi, Jia-Yun Ying, Wei-Ming Chen, Yu-Feng Zhou, Guo-Ping Lu, Cai-Yan Zhang

“…Notably, after adjustment for confounding factors, multivariate analysis revealed that the effect of GM-CSF treatment on 28-day mortality among pediatric septic shock patients did not reach statistical significance, with an odds ratio (OR) of 0.472 and a 95% confidence interval (CI) ranging from 0.153 to 1.457 (P = 0.192). …”
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Research on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial by Mengpei Xu, Ying Wu, Yaqing Zhou, Zhongmei Lv, Wei Chen, Jingjing Fan

“…In addition, the improvements of overall DDS scores and C-DMSES scores of GDM in the observation group were significantly better than those in the control group, so there was statistical significance (P < 0.05). In terms of the pregnancy outcomes and neonatal conditions, the rates of premature delivery and neonatal delivery in the observation group were higher than those in the control group, and there was no difference (P > 0.05) in other aspects of pregnancy outcomes and neonatal conditions. …”
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Vitamin D Status and VDR Genotype in NF1 Patients: A Case-Control Study from Southern Brazil by Larissa Souza Mario Bueno, Clévia Rosset, Ernestina Aguiar, Fernando de Souza Pereira, Patrícia Izetti Ribeiro, Rosana Scalco, Camila Matzenbacher Bittar, Cristina Brinckmann Oliveira Netto, Guilherme Gischkow Rucatti, José Artur Chies, Suzi Alves Camey, Patricia Ashton-Prolla

“…The differences between the groups in genotypic and allelic frequencies for FokI and BsmI VDR gene polymorphisms were small and did not reach statistical significance. These polymorphisms are in partial linkage disequilibrium and the haplotype frequencies also did not differ in a significant way between the two groups (p=0.613).…”
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Application of Targeted Next-Generation Sequencing in Bronchoalveolar Lavage Fluid for the Detection of Pathogens in Pulmonary Infections by Dai X, Xu K, Tong Y, Li J, Dai L, Shi J, Xie H, Chen X

“…The detection rates of tNGS and CTs have statistical significance (66.87% VS 35.12%, P=0.001). Furthermore, a total of 61 cases of antimicrobial resistance genes were detected, including 34 cases of 23S rRNA A2063G, 6 cases of KPC, 5 cases of OXA, 2 cases of CTX-M, 3 cases of IMP, 1 case of NDM and 13 cases of mecA. …”
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Oral lesions and disorders and their prevalence arising from the use of illicit drugs in a prison population. by Marta Relvas, Luciana Rocha, Paulo Rompante, Filomena Salazar, Luís Monteiro, Ana Sofia Vinhas, Maria Gonçalves

“…The level of statistical significance used was α ≤ 0.05. Results: The consumption of illicit drugs proved to be a common practice (86.8%), where cannabis, heroin and cocaine were the most prevalent (29.1%). …”
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Oral health-related quality of life of community-dwellers in the canton of Bern, Switzerland by Roberta Borg-Bartolo, Andrea Roccuzzo, Christian Tennert, Maria Prasinou, Maurus Jäggi, Pedro Molinero-Mourelle, Michael M. Bornstein, Guglielmo Campus

“…Data were collected by a questionnaire (demographic factors, medical history, oral health behavior, dental patient-reported outcomes [dPROs]) and a clinical examination (dental caries, periodontal disease, oral hygiene, mastication). dPROs were evaluated using the OHRQoL-questionnaire Geriatric Oral Health Assessment Index with items related to four domains: functional limitations, pain and discomfort, psychological impact, behavioral impact. χ2 tests, Cochrane Armitage trend tests and binary logistic regression were performed with P < 0.05 statistical significance. Results: The highest prevalence (199/44%, n [total] = 275 participants) of reported problems was observed in the psychological impact domain. …”
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Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy by Nejo Joseph, MBChB, Chris Varghese, MBChB, James Lucocq, MBChB, Matthew J. McGuinness, MBChB, Samuel Tingle, MBChB, Giovanni Marchegiani, PhD, Kjetil Soreide, PhD, Mohammed Abu-Hilal, Jas Samra, Marc Besselink, PhD, Steve White, Sanjay Pandanaboyana, FRCS

“…However, few studies demonstrated robust statistical significance in outcome measures, suggesting an underpowered evidence base and possible selection bias. …”
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Temporal Changes in Plasmodium Falciparum Genetic Diversity and Multiplicity of Infection Across Three Areas of Varying Malaria Transmission Intensities in Uganda. by Mwesigwa, Alex, Kiwuwa, Steven M., Musinguzi, Benson, Kawalya, Hakiim, Katumba, James Davis, Baguma, Andrew, Mutuku, Irene M., Adebayo, Ismail Abiola, Nsobya, Samuel L., Byakika‐Kibwika, Pauline, Kalyango, Joan N., Karamagi, Charles, Nankabirwa, Joaniter I.

“…Statistical comparisons were made using the Kruskal–Wallis test, and temporal trends were analyzed using the Jonckheere–Terpstra test, with statistical significance set at p < 0.05. Results of the 220 samples, 180 were successfully amplified. …”
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