Effect of the modified method of preoperative skin cleaning on prevention of surgical site infection (改良术野皮肤清洁方法预防手术部位感染的效果分析) by ZHANG Wenjun (章文军), ZHANG Mingyang (章明阳), LUO Xiaoping (罗小平)

“…Results The incidence of SSI in the control group was 1. 96% and the study group was 0. 67%, which was statistically significant difference (P < 0. 05). After cleaning the surgical site of 50 randomly selected patients, the CFU after cleaning was fewer than that before cleaning(P < 0. 05). …”
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Empirical Analysis of the Relationship between Poverty and Religion in Iran: A Comparative Study within the Country by Mohammadreza Taleban

“…The findings from this analysis indicated that, after controlling for the effects of social development and economic inequality, poverty continued to exert a statistically significant positive effect on religious commitment. …”
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Identification of the optimal candidates to benefit from surgery and chemotherapy among elderly female breast cancer patients with bone metastases by Yuchen Hu, Junfeng Tang, Xiaofeng Liu, Yusheng Sun, Baojun Gong, Qing Gao

“…Subgroup analysis indicated that individuals classified as low-risk experienced the greatest advantage from surgery and chemotherapy (p < 0.05), whereas the high-risk group did not exhibit a statistically significant difference (p > 0.05). Drawing from the clinicopathological characteristics of elderly female breast cancer patients with bone metastases, this study developed a novel prognostic nomogram to forecast OS at 12, 24, and 36 months, enabling precise survival predictions. …”
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Acceptability, feasibility, and effectiveness of internet-based cognitive behavior therapy for obsessive–compulsive disorder (OCD-NET): a naturalistic pilot trial during the COVID-... by Elisabeth Kohls, Sabrina Baldofski, Julia Scholl, Oskar Flygare, Lina Lundström, Ursula Beyrich-Kolbus, Marc Steinbrecher, Christian Rück, Christine Rummel-Kluge

“…The treatment also resulted in statistically significant improvements in depressive symptoms (d = 0.90 [0.65; 1.15]) and self-efficacy (d = -0.27 [-0.53; -0.00]). …”
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Pre-treatment nutrition-related indicators and the prognosis of patients with newly diagnosed epithelial ovarian cancer: an ambispective cohort study by Shirui Wang, Jingyu Zhu, Ningjuan Wu, Nannan Wang, Xiaohe Dang, Minyi Zhao, Juan Zhao, Ding Ma, Xiaofeng Yang

“…All differences were statistically significant (p &lt; 0.05). Multivariable analysis identified hyperlipidemia as an independent risk factor for PFS (hazard ratio [HR] = 2.083; 95% CI:1.726–2.514; p &lt; 0.001) and OS (HR = 2.158; 95% CI:1.746–2.666; p &lt; 0.001), whereas hypoalbuminemia and anemia were not confirmed as independent prognostic factors. …”
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Satisfacción laboral y violencia en la relación clínica en Fisioterapia en España by Tania Boo-Mallo, Alicia Martínez-Rodríguez, Antía Domínguez-Rodríguez

“…Referring not having suffered psychological violence was related to a higher probability of having JS, even controlling for the rest of the variables studied (OR1 = 0.485; OR2 = 0.611; OR3 = 0.697, respectively for each model).Variables related to health (state of health, symptoms, consumption of tobacco/alcohol/other substances) and to the work environment (working day, work area, autonomy, relationship with superiors/colleagues) were statistically significantly related to JS. Conclusions: Almost 47% of the respondents had very high JS values. …”
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Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction by Enriqueta Felip, Paolo Nuciforo, Elena Garralda, Joan Frigola, Ramon Amat, Garazi Serna, Francesco Grussu, Kinga Bernatowicz, Olivia Prior, Marta Ligero, Christina Zatse, Rodrigo Toledo, Manel Escobar, Raquel Perez-Lopez

“…Cox models using aggregated CT-TIME scores from baseline images revealed a statistically significant reduction in the risk of PFS in the pan-cancer cohort (HR 0.62, 95% CI 0.44 to 0.88, p=0.007), and Kaplan-Meier analysis further confirmed substantial differences in PFS between patients with inflamed and uninflamed status (log-rank test p=0.009).Conclusions The signature holds promise for impacting clinical decision-making, pan-cancer patient stratification, and treatment outcomes in immune checkpoint therapies.…”
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Subtyping Social Determinants of Health in the "All of Us" Program: Network Analysis and Visualization Study by Suresh K Bhavnani, Weibin Zhang, Daniel Bao, Mukaila Raji, Veronica Ajewole, Rodney Hunter, Yong-Fang Kuo, Susanne Schmidt, Monique R Pappadis, Elise Smith, Alex Bokov, Timothy Reistetter, Shyam Visweswaran, Brian Downer

“…ConclusionsThis study identified SDoH subtypes that had statistically significant biclusteredness and replicability, each of which had significant associations with specific adverse health outcomes and with translational implications for targeted SDoH interventions and health care policies. …”
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Meta Analysis of Efficacy and Safety of Moxibustion on Neurogenic Bladder after Spinal Cord Injury by Xueqi HAN, Huirong HUANG, Zhongbiao XIU, Jingling WU, Qinyu LIU, Shaofang MIAO, Xiaona YAN

“…The results of Meta analysis showed that the total effective rate of neurogenic bladder after spinal cord injury in the experimental group was higher than that in the control group[<italic>RR</italic>=1.38, 95%<italic>CI</italic> (1.25,1.52), <italic>P</italic>&lt;0.000 01], could reduce the residual urine volume of NB patients after SCI[urodynamic test group: <italic>MD</italic>=-37.00, 95%<italic>CI</italic> (-43.48,-30.53), <italic>P</italic>&lt;0.000 01; B-scan ultrasonography inspection group: <italic>MD</italic>=-29.88, 95%<italic>CI</italic> (-36.26,-23.50), <italic>P</italic>&lt;0.000 01; urethral catheterization group: <italic>MD</italic>=-33.28, 95%<italic>CI</italic> (-57.03,-9.53), <italic>P</italic>=0.006], could increase the bladder capacity of patients with NB after SCI[urodynamic test group: <italic>MD</italic>=50.73, 95%<italic>CI</italic> (14.47,87.00), <italic>P</italic>=0.006; B-scan ultrasonography inspection group: <italic>MD</italic>=51.07, 95%<italic>CI</italic> (30.06,72.07), <italic>P</italic>&lt;0.000 01], and could effectively regulate the bladder pressure of NB patients after SCI[<italic>MD</italic>=2.03, 95%<italic>CI</italic> (1.07,3.00), <italic>P</italic>&lt;0.000 1], and the difference was statistically significant (<italic>P</italic>&lt;0.05).Conclusion:Moxibustion can effectively reduce bladder residual urine volume, increase bladder capacity and regulate bladder pressure in patients with NB after SCI. …”
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Disturbances of visual perception in non-demented patients with Parkinson’s disease by R. Timofejavaitė, V. Vilda, A. Liveikienė, R. Kaladytė-Lokominienė

“…The difference of MoCA total score (p=0.006), language (p=0.0026) and executive function (p=0.0004) scores between the groups was statistically significant. 40% of PD patients and 10% of controls were diagnosed with mild cognitive impairment (p=0.015). 30% of PD patients and 10% of control subjects scored 7 points or above in HAD anxiety subscale (p=0.021). …”
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Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of... by Wenting Cai, Wenting Cai, Hui Zhang, Hui Zhang, Yan Wu, Yan Wu, Yao Yao, Jinping Zhang

“…Tilavonemab showed a lower incidence of AE, SAE, fall, and urinary tract infections than placebo, and the differences were statistically significant. Most safety analysis results showed no statistical difference.ConclusionThe results indicated that anti-tau protein monoclonal antibodies, such as Semorinemab and Tilavonemab, showed promise in terms of efficacy and safety for managing AD. …”
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Serum Leptin Is not a Diagnostic Marker for Familial Mediterranean Fever Attacks

“…There was a slight increase in serum leptin levels during the attacks but it was not statistically significant (<mml:math alttext="$P>.05$"><mml:mrow><mml:mi>p</mml:mi><mml:mo>&#x003E;</mml:mo><mml:mn>.05</mml:mn></mml:mrow></mml:math>). …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…Despite anecdotal reports linking multiple drugs to PV, corroborating evidence from large datasets is missing.ObjectiveTo examine the extent to which previously reported associations between a comprehensive list of 36 drugs implicated in PV pathogenesis could be replicated using population-level pharmacovigilance data.DesignSeries of observational, retrospective, case-control, pharmacovigilance analyses (one analysis/drug, 36 total).SettingPopulation based.ParticipantsIndividuals who submitted a report of a drug-related adverse event to the FDA from Q4 of 2003 to Q2 of 2023.ExposureCases were identified by the presence of adverse events described by the MedDRA preferred term “pemphigus” (10034280) and then sorted based on exposure to each of the drugs of interest.Main outcomes and measuresReporting Odds Ratios (RORs) quantifying the association between a given drug exposure and reports of pemphigus adverse events.ResultsThe analyses revealed statistically significant associations between reports of pemphigus and exposure to 11/36 previously reported drugs, two of which had particularly high RORs (&gt;200) [gold sodium thiomalate (ROR, 266.0; 95% CI, 202.6-349.3) and hydroxychloroquine (ROR, 282.6; 95% CI, 261.0-306.1)], three had very strong RORs (14-45) [penicillamine (ROR, 30.5; 95% CI, 11.4-81.7), piroxicam (ROR, 14.8; 95% CI, 8.2-26.7), and imiquimod (ROR, 42.3; 95% CI, 26.2-68.3)], and six had modestly strong RORs (2-5) [rifampin (ROR, 2.8; 95% CI, 1.4-5.6), hydrochlorothiazide (ROR, 1.6; 95% CI, 1.2-2.1), irbesartan (ROR, 2.7; 95% CI, 1.6-4.4), lisinopril (ROR, 5.3; 95% CI, 4.5-6.2), nivolumab (ROR, 2.7; 95% CI, 1.8-4.1), and nifedipine (ROR, 3.0; 95% CI, 1.9-5.0)]. …”
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Determining nutritional indices of Dori bleak, Alburnus doriae and Brond Snout, Chondrostoma regium in Zayandehroud River, Central Iran by Omidvar Farhadian, JAVAD BAGHERI, Nasrollah Mahboobi Soofiani, Safiollah Heidari, Eisa Ebrahimi

“…The One-Way ANOVA was used to determine data statistically significant differences. Results and Discussion: The vacuity index was 11.5% for A. doriae and 24% for C. regium. …”
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Impact of Sex on Infection Risk in Patients with Systemic Lupus Erythematosus by R. Borrelli, S. Nicola, F. Corradi, I. Badiu, L. Lo Sardo, N. Rashidy, A. Quinternetto, M. Mazzola, F. Meli, E. Saracco, I. Vitali, S. Negrini, L. Brussino

“…Disease duration (β = 0.0250, <i>p</i> = 0.102) and smoking status (β = 0.4529, <i>p</i> = 0.078) were not statistically significant. Lastly, correlation analysis revealed a significant association between SS-A antibodies and infection rate (r = 0.291, <i>p</i> = 0.003). …”
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Pengaruh Perbedaan Dosis Ekstrak Biji Jarak Pagar (Jatropha curcas) terhadap Jumlah Spermatozoa, Spermatozoa Motil, Berat Testis, dan Diameter Testis pada Mencit Jantan (Mus Muscul... by Haifa Wahyu, Rahmatina B. Herman, Arni Amir

“…The higher the dose given, the lower the sperm count, motile of sperm, testis weight and diameter of the testis, but no statistically significant effect on the number of spermatozoa p = 0</em><em>.…”
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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach by Zhangke Guo, Zhimin Li, Song Bai, Feng Tong, Jia Zheng, Nan Ding, Xiaofeng Li

“…But there were statistically significant differences in S100β serum concentration level at the time of admission to CCU between control group and treatment group. (161.19 ± 6.62 vs. 86.89 ± 9.69 pg/ml, P = 0.01). …”
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Kajian patogenisitas bakteri Edwardsiella ictaluri pada ikan patin Pangasionodon hypophthalmus by Wiwik Susanti, Agustin Indrawati, Fachriyan H Pasaribu

“…Decreased of hematocrit and hemoglobin values of all tread group were statistically significant different (P<0,05) compared to controls. …”
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CBCT Analysis of Mandibular Ramus as a Donor Site for Cortical Bone Graft: A Retrospective Analytical Study by Pallabi Das, Samiran Ghosh, Kaushik Dutta, Richi Burman, Amit Ray, Debolina Pramanick, Siddhartha Chatterjee, Somak Saha

“…The mean surface area was found to be 308.88±75.37 sq mm, whereas the volume was 272.15±92.02 cu mm. Statistically significant differences were found for surface area and volume between genders, with males having greater dimensions than females. …”
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Machine learning based models for predicting presentation delay risk among gastric cancer patients by Huali Zhou, Huali Zhou, Qiong Gu, Rong Bao, Liping Qiu, Yuhan Zhang, Fang Wang, Wenlian Liu, Lingling Wu, Li Li, Yihua Ren, Lei Qiu, Qian Wang, Gaomin Zhang, Xiaoqing Qiao, Wenjie Yuan, Juan Ren, Min Luo, Rong Huang, Qing Yang, Qing Yang

“…After collecting the data, statistical analysis was performed to identify discriminative variables for the prediction of presentation delay and 13 statistically significant variables are selected to develop machine learning models. …”
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