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  1. 6501
  2. 6502

    Pharmacodynamic characteristics and influencing factors of tapentadol for chronic pain relief under dose titration by Liang Xin, Haoxiang Zhu, Haoxiang Zhu, Suping Niu, Xie Han, Hongxian Pang, Jiangfan Li, Ye Hu, Xuhong Wang, Lujin Li, Lujin Li, Yi Fang

    Published 2025-01-01
    “…Additionally, subgroup analysis suggested that higher titration doses, higher baseline NRS levels, the use of extended-release tapentadol, and a smaller proportion of male participants were trends associated with better analgesic effects, although the differences were not statistically significant. Moreover, the study found that tapentadol was significantly more effective in treating lower back pain compared to non-lower back pain.ConclusionThis research successfully developed a pharmacodynamic model for dose-titrated tapentadol administration, which can simulate the temporal changes in analgesic effects of tapentadol across different clinical scenarios. …”
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  3. 6503

    Estimating the need for diabetic retinopathy services in north India: evidence from a population-based survey in the catchment population of an eye care provider in central Uttar P... by Andrew Bastawrous, Vaibhav Jain, Ian McCormick, Shalinder Sabherwal, Ishaana Sood, Atanu Majumdar, Shamanna B R, Mohd Javed, Sandeep Buttan, Simrat Chandi, Basitali Lakhani, Shreya Tyagi, Utsav Deep

    Published 2025-01-01
    “…The odds of DR were higher with duration of diabetes >10 years and poor glycaemic control (OR of 1.8 and 1.6, respectively), but this was not found to be statistically significant.Conclusion The prevalence of DR in this predominantly rural setting was found to be higher than the national average. …”
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  4. 6504

    Abdominal synthetic CT generation for MR-only radiotherapy using structure-conserving loss and transformer-based cycle-GAN by Chanwoong Lee, Chanwoong Lee, Young Hun Yoon, Young Hun Yoon, Young Hun Yoon, Jiwon Sung, Jun Won Kim, Yeona Cho, Jihun Kim, Jaehee Chun, Jin Sung Kim, Jin Sung Kim, Jin Sung Kim

    Published 2025-01-01
    “…The MAE and PSNR were statistically significant. The global gamma passing rates of the proposed method at 1%/1 mm, 2%/2 mm, and 3%/3 mm were 86.1 ± 5.9%, 97.1 ± 2.7%, and 98.9 ± 1.0%, respectively.ConclusionThe proposed method significantly improves image metric of sCT for the abdomen patients than original cycle-GAN. …”
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  5. 6505

    Prevalence and risk factors for long COVID among cancer patients: a systematic review and meta-analysis by Hongkun Xu, Hongkun Xu, Tingting Lu, Yajie Liu, Jingqi Yang, Simeng Ren, Baojin Han, Honghao Lai, Long Ge, Jie Liu

    Published 2025-01-01
    “…Patients with comorbidities had a significantly higher risk of experiencing long COVID [odds ratio (OR) = 1.72; 95% CI, 1.09 to 2.70; p = 0.019]. No statistically significant differences in sex, primary tumor, or tumor stage were detected.ConclusionNearly a quarter of cancer patients will experience long COVID after surviving from SARS-CoV-2 infection, and this would even last for 1 year or longer. …”
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  6. 6506

    Quantitative swept-source optical coherence tomography angiography (SS-OCTA) analysis of macular microvascular alterations in Bietti crystalline dystrophy by Shiyi Yin, Jinyuan Wang, Haihan Zhang, Xuan Yang, Jingting Luo, Wenbin Wei

    Published 2025-04-01
    “…From stage 1 to stage 2, VD in all retinal layers decreased significantly (P < 0.05), whereas differences between stages 2 and 3 were not statistically significant (P > 0.05). The FAZ area and perimeter showed no significant difference across the three stages (P > 0.05). …”
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  7. 6507

    Balance Changes in Adult Cancer Survivors Participating in a 16-Week Therapeutic Yoga Program by Mark J. Miller BS, Daniel C. Hughes PhD, Nydia T. Darby DPT, Tim Calderon MS, Darpan I. Patel PhD, Monica C. Serra PhD, Amelie G. Ramirez Dr. PH, Alexis Ortiz PT, PhD, Gustavo J. Almeida PT, PhD

    Published 2025-01-01
    “…Changes in both balance assessment conditions were not statistically significant (eyes opened: 80.06 ± 374.99, p  = .702; eyes closed: −1.82 ± 24.01, p  = .068). …”
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  8. 6508

    Assessment of factors influencing job satisfaction among healthcare workers' in public hospitals in Nairobi County, Kenya by Lifuleze CM, Muhonja FH, Muchiri J

    Published 2025-01-01
    “…Results: The study found that promotions ( p-value<0.001) with OR =1.790 and 95% CI = (1.090, 2.939), Training and development (p-value<0.001) with OR = 1.960 and 95% CI = (1.214, 3.165), Communication (p-value=0.001) with OR = 1.189 and 95% CI = (0.687, 2.059), Supervision (P-Value < 0.001) with OR = 1.380 and 95% CI = (0.805, 2.365), quality of buildings in terms of space (p-value<0.001) with OR = 1.505 and 95% CI = (0.924, 2.453), Equipment adequacy (p-value<0.001) with OR = 2.871 and 95% CI = (1.698, 4.854), Availability of PPEs’ (p-value=0.022) with OR = 2.394 and 95% CI = (1.316, 4.357), and Availability of amenities such as toilets and water (p-value=0.04) with OR = 1.844 and 95% CI = (1.458, 2.556) had a statistically significant effect on satisfaction/dissatisfaction by Healthcare workers. …”
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  9. 6509

    How does residency program reputation influence American shoulder and elbow surgeons fellowship match results? by Alexander Jurayj, BA, Taylor Timoteo, DO, Julio Nerys-Figueroa, BS, Johnny Kasto, MD, Jared M. Mahylis, MD, Stephanie J. Muh, MD

    Published 2025-02-01
    “…Results: There was a statistically significant difference with residency tier and average matched rank by fellowship program (P < .001). …”
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  10. 6510

    Hypothermia during Surgical Treatment of Type A Aortic Dissection: A 16 Years’ Experience by Francesco Macrina, Maria Cristina Acconcia, Luigi Tritapepe, Mizar D’abramo, Wael Saade, Alessandra Capelli, Fabio Miraldi

    Published 2020-01-01
    “…The global incidence of complications was statistically reduced in HT group: we found a statistical significant reduction of intestinal ischemia, and a similar trend also for other complications analyzed, such as infections. …”
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  11. 6511

    Addressing racial and ethnic disparities in premature exits from permanent supportive housing among residents with substance use disorders by Talia J. Panadero, Sonya Gabrielian, Marissa J. Seamans, Lillian Gelberg, Jack Tsai, Taylor Harris

    Published 2025-01-01
    “…Hispanic/Latino residents with at least one SUD had 1.9 times the hazard compared to those without SUDs; however, this association was not statistically significant (95% CI: 0.85–4.37). African American/Black residents with at least one SUD had 1.2 times the hazard compared to those without SUDs (95% CI: 0.85–1.64), indicating no evidence of an association with negative PSH exits. …”
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  12. 6512

    Digital Exclusion and Depressive Symptoms among Older People: Findings from Five Aging Cohort Studies across 24 Countries by Jingjing Wang, Xinran Lu, Sing Bik Cindy Ngai, Lili Xie, Xiaoyun Liu, Yao Yao, Yinzi Jin

    Published 2025-01-01
    “…This association remained statistically significant in the MSAS-adjusted model across all cohorts: HRS [incidence rate ratio (IRR), 1.37; 95% confidence interval (CI), 1.28 to 1.47], ELSA (IRR, 1.32; 95% CI, 1.23 to 1.41), SHARE (IRR, 1.30; 95% CI, 1.27 to 1.33), CHARLS (IRR, 1.62; 95% CI, 1.38 to 1.91), and MHAS (IRR, 1.31; 95% CI, 1.26 to 1.37); all Ps < 0.001. …”
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  13. 6513

    Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets by Yuling Chen, Yan Li, Yuan Xu, Qing Lv, Yuanchun Ye, Jieruo Gu

    Published 2025-12-01
    “…Statistical analysis was conducted using the R software package, and a p-value of less than 0.05 was considered statistically significant.Results Pathways enrichment analysis revealed the involvement of NK cell-mediated immune pathways and regulation of the innate immune response, indicating the crucial role of innate immunity, especially NK cells, in AS pathogenesis. …”
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  14. 6514

    The hydraulic performance and clogging characteristics of a subsurface drip irrigation system operating for five years in the North China plain by Li Zaiyu, Mo Yan, Gao Hao, Gong Shihong, Zhang Yanqun, Li Guangyong, Wu Feng

    Published 2025-02-01
    “…The results revealed that Dra and Cu significantly decreased (p < 0.05) with increasing nitrogen application, whereas the changes in irrigation and aeration were not statistically significant. The average Dra and Cu for the entire system were 88.3 % and 91.2 %, respectively, indicating good uniformity of the water distribution in the SDI system. …”
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  15. 6515

    Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece by Petros Galanis, Aglaia Katsiroumpa, Irene Vraka, Katerina Kosiara, Olga Siskou, Olympia Konstantakopoulou, Theodoros Katsoulas, Parisis Gallos, Daphne Kaitelidou

    Published 2023-10-01
    “…Anxiety and depressive symptoms were worse after the post-COVID-19 syndrome (p<0.001 in both cases). A statistically significant reduction in quality of life was observed among patients after the post-COVID-19 syndrome (p<0.001 for both EQ-5D-3L index value and EQ-5D-3L VAS). …”
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  16. 6516

    Simulation of the heat mitigation potential of unsealing measures in cities by parameterizing grass grid pavers for urban microclimate modelling with ENVI-met (V5) by N. Eingrüber, A. Domm, W. Korres, K. Schneider

    Published 2025-01-01
    “…On temporal average for the 3 d heat event, statistically significant mean temperature differences of <span class="inline-formula">−5.8</span> K for surface temperature and <span class="inline-formula">−1.1</span> K for air temperature were simulated. …”
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  17. 6517

    Role of Cardiac Magnetic Resonance Imaging in Detecting Myocardial Viability in Patients with Chronic Ischaemic Heart Disease: A Prospective Observational Study by Subhosree Dey, Parul Dutta, Bornali Dutta, Baloy Jyoti Talukdar, Sushant Agarwal, Dhiraj Baruah

    Published 2025-01-01
    “…A p-value (using Chi-square test) of less than 0.05 was considered statistically significant. Results: The mean age was 52±14 years. …”
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  18. 6518

    Late blight resistant potato hybrid clones in the VIR collection of plant genetic resources by E. V. Rogozina, N. A. Chalaya, M. A. Kuznetsova, V. N. Demidova, A. N. Rogozin, T. I. Smetanina, M. P. Beketova, O. A. Fadina, E. Е. Khavkin

    Published 2019-01-01
    “…The relationship between rAUDPC values in different years of study was statistically significant for hybrids and potato varieties (r = 0.87-0.94). …”
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  19. 6519

    Impact of healthcare-associated infections on in-hospital outcomes during the COVID-19 era: a multicenter comparative study of 20,942 isolated microorganisms from ICU patients by Armin Khavandegar, Zeinab Siami, Aziz Rasouli, Pershang Nazemi, Anoosha Gull

    Published 2025-02-01
    “…There was a statistically significant difference in UTI, PMEU, BSI, and others, with an increase in PMEUs (13.5% vs. 17.1%) and BSI (22.7% vs. 24.5%) and a decrease in UTIs (24.5% vs. 22.2%) and others (4.2% vs. 2.6%) in COVID-19 era compared to pre-COVID-19. …”
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  20. 6520

    Comparison of Placental Doppler Ultrasound indices in Pregnant Women with Iron Deficiency Anemia, Minor Beta-Thalassemia and Healthy Pregnant in first half of pregnancy by Zahra Rahmani, Maryam Abdi Valikchali, Tahere Gelini Moghaddam, Shahabodin Gharahveysi

    Published 2024-12-01
    “…Results: The results indicated a statistically significant difference in the mean resistance index of the placental spiral artery among the three groups. …”
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