Association of ambient temperature with social isolation among the community-dwelling Chinese older adults: A cross-sectional study in Hong Kong by Eliza Lai-Yi Wong, Hong Qiu, Kin-Fai Ho, Annie Wai-Ling Cheung, Hera Leung, Frank Youhua Chen, Eng-Kiong Yeoh

“…Meanwhile, we observed statistically significant associations of sunshine exposure, gender, health status, marital status, living alone, religion, and housing type with LSNS-6 score or social isolation. …”
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Acute enteritis with pelvic SBRT: Influence of bowel delineation methods by Akshay Dinesan, Maneesh Singh, Prachi Mehta, Priyamvada Maitre, Vedang Murthy

“…Objectively, the volume of the bowel structures receiving 7 Gy, 14 Gy, and 25 Gy did not show any statistically significant difference between cases and controls. …”
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Prostate cancer incidence and mortality linked to metalworking fluid exposure: a systematic review and meta-analysis by Zahra Moradpour, Amin Barik, Goljamal Jorjani, Mohammad Reza Taherian, Sepideh Tousizadeh, Sepideh Tousizadeh, Aram Halimi, Aram Halimi, Yaser Soleimani, Mobina Karimian, Tina Khavari, Fateme Azizi Kalankari, Fatemeh Asadipour, Mojtaba Azari, Niloofar Yousefzadeh Shakouri, Saeideh Karamian, Nasser Bahari, Alireza Mosavi Jarrahi

“…Meta-analysis revealed an overall RR of 1.06 (95% CI: 1.01-1.11) for prostate cancer incidence and an overall SMR of 1.20 (95% CI: 1.09-1.31) for prostate cancer mortality, indicating a statistically significant increased risk and mortality among MWF-exposed workers.ConclusionsThese findings carry significant implications for workplace safety regulations. …”
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Dietary diversity and its associated factors among school children in conflict affected communities of southern Ethiopia by Tagese Yakob, Eskinder Israel, Begidu Yakob, Mekdes Meshesha, Endale Jambo, Tadewos Utalo, Awoke Abraham

“…A p-value less than 0.05 on multivariate logistic regression indicated a statistically significant association.ResultsThe overall response rate of this study was 98.5%. …”
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Comparing physician associates and foundation year two doctors-in-training undertaking emergency medicine consultations in England: a mixed-methods study of processes and outcomes by Simon de Lusignan, Mary Halter, Carly Wheeler, Laura Nice, Sally Brearley, James Ennis, Jonathan Gabe, Heather Gage, Phil Begg, Chao Wang, Jim Parle, Vari Drennan

“…If seen by a physician associate, patients were more likely receive an X-ray investigation (OR 2.10, 95% CI 1.72 to 4.24), p<0.001), after adjustment for patient characteristics, triage severity of condition and statistically significant clinician intraclass correlation. …”
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Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study by Daijiro Kabata, Ayumi Shintani, Masanori Akira, Masahiko Hara, Hideo Ishikawa, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Yukio Nagasaka, Kouji Yamamoto

“…Although not statistically significant by the adjusted analysis of variance with multiple imputation of missing variables, cryptogenic haemoptysis tended to show the most favourable outcome and non-tuberculous mycobacterium showed the worst outcome (adjusted p=0.250).Conclusions We demonstrated the safety and long-term efficacy of elective ssBAE using platinum coils and established that it can be a valuable therapeutic option for treating patients with haemoptysis.…”
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Optic nerve sheath diameter/eyeball transverse diameter ratio by ultrasound in prediction of increased intracranial pressure in children with viral encephalitis by Chun Zhao, Peng-Cheng Sun, Ke-Jie Fang, Hui-Hui Fu, Li-Feng Wei, Yin-Yun Miao, Xin-Xin Guo, Xiao-Ling Weng

“…The data on the 7th day of treatment in increased ICP group was significantly lower than the data before treatment (p < 0.01), but not statistically significant compared to the data on the 3rd day of treatment (p = 0.650). …”
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Single-nucleotide polymorphisms in dizygotic twin ovine fetuses are associated with discordant responses to antenatal steroid therapy by Erin L. Fee, Haruo Usuda, Sean W. D. Carter, Hideyuki Ikeda, Tsukasa Takahashi, Yuki Takahashi, Yusaku Kumagai, Michael W. Clarke, Demelza J. Ireland, John P. Newnham, Masatoshi Saito, Sebastian E. Illanes, Binny Priya Sesurajan, Liang Shen, Mahesh A. Choolani, Gokce Oguz, Adaikalavan Ramasamy, Sara Ritchie, Andrew Ritchie, Alan H. Jobe, Matthew W. Kemp

“…Results ANS-exposed female fetuses had lower arterial partial pressure of carbon dioxide (PaCO2) values than male fetuses (76.5 ± 38.0 vs. 97.2 ± 42.5 mmHg), although the observed difference was not statistically significant (p = 0.1). Only 52% of ANS-treated twins were concordant for lung maturation responses. …”
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The state of combined thoracoabdominal triple-organ transplantation in the United States by Emily G. Dunbar, BS, Ye In Christopher Kwon, BA, Matthew Ambrosio, MS, Inna F. Tchoukina, MD, Keyur B. Shah, MD, David A. Bruno, MD, Walker A. Julliard, MD, Josue Chery, MD, Vigneshwar Kasirajan, MD, Zubair A. Hashmi, MD

“…There were no statistically significant differences in long-term survival between TOTs (p = 0.13). …”
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Predictive role of modifiable factors in stroke: an umbrella review by Yue Wang, Lu Wen, Xiaotong Wang, Man Liang, Fanxin Zeng, Yuetian Yang, Fangfang Nie, Mengke Shang, Na Ta, Lanxin Ou, Zhibin Yang, Wanyang Liu

“…Excess significance test was used to investigate whether the observed number of studies (O) with nominally significant results (‘positive’ studies, p<0.05) was larger than the expected number of significant results (E). Statistically significant (p<0.05) associations were rated into five levels (strong, highly suggestive, suggestive, weak and no) using specific criteria. …”
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Lymphatic leaks – success of intranodal lymphangiogram first strategy by Alan Campbell, Diana Velazquez-Pimentel, Matthew Seager, Richard Hesketh, Julian Hague, Jowad Raja, Jocelyn Brookes, An Ngo, Miles Walkden, Anthie Papadopoulou, Daron Smith, Borzoueh Mohammadi, Ravi Barod, Mohammed Rashid Akhtar, Jimmy Kyaw Tun, Deborah Elise Low, Ian Daniel Renfrew, Tim Fotheringham, Conrad von Stempel

“…Overall clinical success of all lymphatic interventions was 69% (22 of 32 patients) at a median of 11 days (IQR 5–34). No statistically significant correlation between the site of leakage, aetiology or embolisation technique correlated with clinical success. …”
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Comparing efficacy and safety of low-dose versus standard-dose antiplatelet therapy in stroke patients: a meta-analysis by Zhao Ren, Chunxing Li, Xin Zhang, Lichaoyue Sun, Hui Zhu, Dongxiao Wang, Yumin Wang, Shuo Liang, Guanchun Wang

“…Low-dose clopidogrel and low-dose prasugrel reduce the risk of bleeding compared to standard-dose clopidogrel, but there is no statistically significant difference. Low-dose aspirin significantly reduces the risk of bleeding compared to standard-dose aspirin.ConclusionIn patients with stroke in Asia, low-dose antiplatelet therapy significantly reduces the risk of bleeding compared to standard doses, with consistent risks of stroke, MI, ACD, major bleeding, and discontinuation due to bleeding.…”
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The Influence of Overnight Orthokeratology on Ocular Surface and Meibomian Gland Dysfunction in Teenagers with Myopia by Xiu Wang, Jing Li, Rui Zhang, Na Li, Yi Pang, Yan Zhang, Ruihua Wei

“…The meibomian gland lipid secretion scores after wearing OOK were higher than those of the prewearing level, however, without statistically significant difference (P>0.05). No significant differences of the degree of difficulty of lipid excretions were detected after the initiation of OOK (P>0.05). …”
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Carotid Artery Stenting Outcomes by Neurointerventional Surgeons (CASONI) by Mohamad Ezzeldin, Ameer E. Hassan, Ali Kerro, Maria Martucci, Muhammad Shazam Hussain, Osman Mir, Faheem G. Sheriff, Peter Kan, Chizoba Ezepue, Nazli A. Janjua, Kaiz S. Asif, Ramesh Grandhi, Ali Alaraj, Muhammad Niazi, Ossama Yassin Mansour, Michael Chen, Saif Bushnaq, Omar Tanweer, Adnan H. Siddiqui, Adam Delora, Rime Ezzeldin, Bains Navpreet, Varun Chaubal, Mohammad Ammar Abdulrazzak, Hamzah Saei, Gustavo J. Rodriguez, Mohammad AlMajali, Gautam Edhayan, Amer Al Shekhlee, Christopher Hadjialiakbari, Musaab Froukh, Walid K. Salah, Elsa Nico, Adrusht Madapoosi, Yazan Radiaideh, Darko Quispe‐Orozco, Oz Haim, Noel Garza, Alberto Maud, Morgan Rolon‐Newton, Benan Barakat, Tejas Gowda, Muhammad Monk, Zuhair Ali, Tunmi Anwoju, Osama O. Zaidat, Farhan Siddiq

“…The primary outcomes occurred in 26 (1.8%) cases, with 13 (0.9%) death, 8 (0.55%) symptomatic ischemic stroke, 4 (0.28%) symptomatic intracranial hemorrhage, and 1 (0.07%) myocardial infarction. A statistically significant increase in all outcomes correlated with advanced age (P = 0.001), women (P = 0.013), aortic arch type 3 (P = 0.01), and higher preprocedural modified Rankin score (P = 0.006). …”
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Ultrasound super-resolution imaging for non-invasive assessment of microvessel in prostate lesion by Xin Huang, Huarong Ye, Yugang Hu, Yumeng Lei, Yi Tian, Xingyue Huang, Jun Zhang, Yao Zhang, Bin Gui, Qianhui Liu, Ge Zhang, Qing Deng

“…Results The tumor markers of prostate in the malignant group were all higher than those in the benign group, and the differences were statistically significant (P < 0.001). The TIC parameters of CEUS revealed that the PKI, AS, DS, and AUC were significantly higher in the malignant group than in the benign group (P < 0.001), whereas the RT, TTP and FT in the malignant group were significantly lower (P < 0.001). …”
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Risk analysis of cardiovascular toxicity in patients with lymphoma treated with CD19 CAR T cells by Yang Liu, Xiaoshuang Yuan, Xu Yang, Bo Yang, Guangyang Liu, Xiao Xu, Sanbin Wang, Zhixu He, Feiqing Wang, Yanju Li

“…The incidence of CV events in the elderly was higher than that in adults, and it was statistically significant. Furthermore, the incidence of CV events and hypotension is strongly associated with patients with CRS. …”
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Seasonal fluctuation of total water intake and hydration status among young men and women: a prospective cohort study by Jianfen Zhang, Jianfen Zhang, Na Zhang, Na Zhang, Junbo Lu, Junbo Lu, Shufang Liu, Yongwei Lin, Guansheng Ma, Guansheng Ma

“…Chinese recommendations for TWI were met by 13.9% to 22.8% of participants, and recommendations for total fluid intake were met by 10.1% to 16.5%, but these differences were not statistically significant (p &gt; 0.05). Urinary and plasma biomarkers differed significantly among the four seasons (p &lt; 0.05), with osmolality and urine specific gravity (USG) being significantly higher in summer than in other seasons (p &lt; 0.05). …”
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Echo- and B-Type Natriuretic Peptide-Guided Follow-Up versus Symptom-Guided Follow-Up: Comparison of the Outcome in Ambulatory Heart Failure Patients by Gani Bajraktari, Nicola Riccardo Pugliese, Andreina D’Agostino, Gian Marco Rosa, Pranvera Ibrahimi, Luan Perçuku, Mario Miccoli, Gian Giacomo Galeotti, Iacopo Fabiani, Roberto Pedrinelli, Michael Henein, Frank L. Dini

“…Survival curves exhibited statistically significant differences using Mantel–Cox analysis. …”
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Conduction system pacing using electro-anatomical mapping-guided system vs. fluoroscopy: a systematic review, meta-analysis and economic evaluation by Beatriz León-Salas, Beatriz León-Salas, Beatriz León-Salas, Beatriz León-Salas, Diego Infante-Ventura, Diego Infante-Ventura, Diego Infante-Ventura, Aránzazu Hernández-Yumar, Aránzazu Hernández-Yumar, Aránzazu Hernández-Yumar, Renata Linertová, Renata Linertová, Renata Linertová, Renata Linertová, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Himar González-Pacheco, Himar González-Pacheco, Himar González-Pacheco, Himar González-Pacheco, Analía Abt-Sacks, Analía Abt-Sacks, Analía Abt-Sacks, Analía Abt-Sacks, Javier García-García, Raúl Quirós-López, Raúl Quirós-López, María M. Trujillo-Martín, María M. Trujillo-Martín, María M. Trujillo-Martín, María M. Trujillo-Martín

“…A budget impact analysis was also conducted with a five-year horizon.ResultsSeven comparative observational studies (N = 231), analyzing the use of EAM versus fluoroscopy were selected. Statistically significant differences were observed in total fluoroscopy time: −9.87 minutes (95%CI:−14.20, −5.53, p &lt; 0.01; I2 = 95%; k = 7; n = 231); His-lead fluoroscopic time: −8.08 minutes (95%CI:−10.36, −5.81, p &lt; 0.01; I2 = 0%; k = 2; n = 50); and His-lead radiation dose: −17.21 mGy (95%CI:−24.08, −10.34, p &lt; 0.01; k = 1; n = 20). …”
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Discovery and Spectroscopic Confirmation of Aquarius III: A Low-mass Milky Way Satellite Galaxy by W. Cerny, A. Chiti, M. Geha, B. Mutlu-Pakdil, A. Drlica-Wagner, C. Y. Tan, M. Adamów, A. B. Pace, J. D. Simon, D. J. Sand, A. P. Ji, T. S. Li, A. K. Vivas, E. F. Bell, J. L. Carlin, J. A. Carballo-Bello, A. Chaturvedi, Y. Choi, A. Doliva-Dolinsky, O. Y. Gnedin, G. Limberg, C. E. Martínez-Vázquez, S. Mau, G. E. Medina, M. Navabi, N. E. D. Noël, V. M. Placco, A. H. Riley, I. U. Roederer, G. S. Stringfellow, C. R. Bom, P. S. Ferguson, D. J. James, D. Martínez-Delgado, P. Massana, D. L. Nidever, J. D. Sakowska, L. Santana-Silva, N. F. Sherman, E. J. Tollerud, DELVE Collaboration

“…Based on calcium-triplet metallicities of the six brightest red giant members, we find that Aquarius III is very metal-poor ([Fe/H]= − 2.61 ± 0.21) with a statistically significant metallicity spread ( ${\sigma }_{[\mathrm{Fe}/{\rm{H}}]}={0.46}_{-0.14}^{+0.26}$ dex). …”
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