Effects of cardiac contractility modulation on autophagy and apoptosis of cardiac myocytes in rabbits with chronic heart failure. by Qingqing Hao, Shilin Lv, Jing Zhang, Huiliang Liu

“…However, the expression of ALDH2 mRNA in the CCM group was not statistically significant. The expression of Bcl-2, ALDH2 protein and mRNA increased after CCM intervention, and the expression of Bax, Caspase-3 protein and mRNA decreased (P<0.05). 3) The apoptosis situation in the Sham group was similar to that of normal myocardium, compared with the Sham group, the number of apoptotic bodies increased, and the apoptosis percentage of cardiomyocytes increased significantly (P<0.05). …”
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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…Biomarker evaluation showed a statistically significant reduction in blood claudin-5 and a trend toward reduction of blood homocysteine. …”
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Estimation of Knowledge, Attitude and Prevalence of Female Sex Dysfunction in Elderly Pakistani Women by Khola Noreen, Farah Ayyaz, Lubna Meraj, Tabinda Khalid, Javara Malik, Muhammad Akram Randhawa

“…Data was analysed using SPSS version 26 and a p-value less than 0.05 was taken as statistically significant. Results: A total of 150 middle-aged and elderly women were randomly included in the study.The females reporting with some medical or gynaecological problem at the teaching hospital of RMU, willing to participate and gave informed written consent where recruited. …”
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Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3 by Han Chu, Qi-Fei Deng, Yuan Fang

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P &lt; 0.05).ConclusionsThis is the first time we found the expression of NLRP3 in cryptorchidism. …”
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Interventional effects of different track and field sports on human cardiovascular function indicators and physiological energy metabolism by Ruibin Jing, Zhengwei Wang, Choi Mee-Seong

“…Result The weight, systolic blood pressure, and diastolic blood pressure of different populations were not statistically significant in a quiet state (p > 0.05). The waist to hip ratios of the short-distance and long-distance running teams were 0.75 ± 0.03 and 0.76 ± 0.03, respectively, which showed significant differences compared to ordinary students (p < 0.05). …”
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Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

“…With respect to renal function, there was a statistically significant difference in serum creatinine (SCr) (lowest in the low-risk group and highest in the high-risk group) but no such difference in estimated glomerular filtration rate (eGFR) among the three groups. …”
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Exploring effects of a booster workshop on progression and retention of resuscitation skills of residents when added to regular low-dose simulation by Hui-Wen Chen, Hung-Wei Tsai, Yi-Chun Chen, Yu-Jui Chiu, Enoch Yi-No Kang, Yi-Ting Hsu, S. Barry Issenberg, Jen-Chieh Wu

“…Results Outcome measures in medical task performance and team leader behavior showed statistically significant improvement in both groups (p < 0.05) from pre-test to mid-test. …”
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Minimally invasive internal splinting technique for acute closed Achilles tendon rupture by Songlin Liu, Liang Ma

“…Furthermore, the range of motion (ROM) was measured at (44.27 ± 1.08), significantly surpassing the preoperative value of (26.91 ± 2.09), with all differences being statistically significant (p < 0.05). Conclusion The procedure is simple. …”
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Mind at rest, mind at risk: A prospective population-based study of sleep and subsequent mental disorders by Mari Hysing, Allison G. Harvey, Ann Kristin Skrindo Knudsen, Jens C. Skogen, Anne Reneflot, Børge Sivertsen

“…Although the associations were attenuated after adjustment, they remained statistically significant. Conclusion: Sleep disturbances, including insomnia and abnormal sleep durations, predict mental health issues in young adults, even after accounting for baseline mental health and somatic health. …”
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Does Anemia Have a Potential Effect on Type 2 Hepatorenal Syndrome? by Sondes Bizid, Haythem Yacoub, Ghanem Mohamed, Bahaa Ben Slimane, Khouloud Boughoula, Hatem Ben Abdallah, Riadh Bouali, Nabil Abedelli

“…Logistic regression analysis showed that lower hemoglobin levels and higher MELD and CTP scores were statistically significant for an onset of type 2 HRS. Conclusion. …”
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Can integrated care interventions strengthen primary care and improve outcomes for patients with chronic diseases? A systematic review and meta-analysis by Yuqi Zhang, Jonathan Stokes, Laura Anselmi, Peter Bower, Jin Xu

“…For wider outcomes, the only statistically significant effect was found on costs (effect size: 0.02, 95% CI 0.02–0.03). …”
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Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience) by I. Yu. Pirogova, N. B. Kovaleva, E. P. Patlusov, E. S. Radchenko

“…In 83,7% of the patients included in the analysis no statistically significant dynamics of liver tissue density was noted. …”
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Practice on Metered Dose Inhaler Techniques and Its Associated Factors among Asthmatic Patients at Debre Markos Comprehensive Specialized Hospital, East Gojjam, Ethiopia: A Prospec... by Tadele Asmare, Anteneh Belayneh, Bekalu Dessie

“…P values less than 0.05 were considered to be statistically significant in all cases. Results are presented in tables, figures, numbers, and percentages. …”
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Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients by Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras

“…However, there was no statistically significant difference genotype distribution between the type 2 diabetes patients and control group for IGF2BP2 rs4402960 (G/T) gene polymorphisms. …”
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<i>Toxoplasma gondii</i> and Rabies—The Parasite, the Virus, or Both? by Ragan Wilson, Shannon Caseltine, Edith Will, Jeremiah Saliki, Ruth C. Scimeca

“…Analysis among <i>T. gondii</i>-positive hosts revealed a statistically significant difference in dogs when comparing neutered vs. intact males, with 7.94% (5/63) <i>T. gondii</i>-positive neutered males and 1.61% (3/186) <i>T. gondii</i>-positive intact males (<i>p</i> = 0.02). …”
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Risk Factors of Upper Limb Lymphedema after Breast Cancer Surgery in Women by Jinghui HUANG, Feng HUANG, Pei ZHU, Shuainan SHEN, Kefan CAO, Cheng LIU, Fanfu FANG, Bai LI

“…In the univariate analysis of the influencing factors of BCRL, there were 9 factors including BMI, hypertension, postoperative chemotherapy, postoperative radiotherapy, postoperative endocrine therapy, number of lymph node dissection, positive lymph nodes and age of diagnosis, which were statistically significant differences between the edema group and the non-edema group. …”
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The Effect of Exercise Intervention on Non-Specific Neck Pain and Head and Neck Angles Among Adult Smartphone Users by Sara Tabanfar, Seyvan Sobhani, Ali Safari Variani, Sakineh Varmazyar

“…Additionally, CVA showed a statistically significant increase in the experimental group (t=-11.75, P=0.004).Conclusion: Over half of the experimental group reported reduced neck pain severity after the exercise intervention. …”
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Autonomic Nervous System Activity before Atrial Fibrillation Onset as Assessed by Heart Rate Variability by Jean-Marie Grégoire, Cédric Gilon, François Marelli, Pascal Godart, Hugues Bersini, Stéphane Carlier

“…We measured a statistically significant increase in very-low-frequency (VLF), low-frequency (LF), high-frequency (HF), RMSSD and pNN50 between 35 minutes and 5 minutes before AF onset. …”
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Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study by Parsa Mohammadi, Hesam Aldin Varpaei, Alireza Khafaee pour khamseh, Mostafa Mohammadi, Mojgan Rahimi, Amirhossein Orandi

“…There was a statistically significant association between chronic kidney disease (CKD) and mNUTRIC risk (OR = 13.5, 95% CI (1.89–16.05), P=0.002), diabetes mellitus (DM) and MNA risk (OR = 2.82, 95% CI (1.01–7.83), P=0.041), hypertension (HTN) and MNA risk (OR = 5.63, 95% CI (2.26–14.05), P<0.001), and malignancy and mNUTRIC risk (P=0.048). …”
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Dynamically triggered seismicity in Japan following the 2024 M w 7.5 Noto earthquake by Like An, Bogdan Enescu, Zhigang Peng, Masatoshi Miyazawa, Hector Gonzalez-Huizar, Yoshihiro Ito

“…The analysis of a longer-term (1 month) seismicity pattern, based on the JMA catalog, revealed a statistically significant increase of seismicity in the remote Akita–Yakeyama (Tohoku region) volcanic area, following the Noto earthquake. …”
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