Epidemiological characteristics of elderly osteoporosis fractures and their association with air pollutants: a multi-center study in Hebei Province by Guangzhao Hou, Qian Xiao, Zhipeng Ye, Shihang Liu, Shuai Zhou, Yan Wang, Wenjing Li, Yingze Zhang, Hongzhi Lv

“…The single-day lag effect of SO2 was statistically significant from day 9 to day 12, reaching its maximum at day 11 (RR = 1.054, 95% CI: 1.032, 1.71). …”
Get full text

<i>Cannabis sativa</i> L. Extract Increases COX-1, COX-2 and TNF-α in the Hippocampus of Rats with Neuropathic Pain by Joanna Bartkowiak-Wieczorek, Małgorzata Jamka, Radosław Kujawski, Marcin Hołysz, Agnieszka Bienert, Kamila Czora-Poczwardowska, Michał Szulc, Przemysław Mikołajczak, Anna Bogacz, Anna-Maria Wizner, Karolina Wielgus, Ryszard Słomski, Edyta Mądry

“…The effects of different doses (5.0–40.0 mg/kg) of two <i>Cannabis sativa</i> L. extracts (B and D) on COX-1, COX-2, TNF-α, and NF-κB mRNA and protein levels were examined in the rat hippocampus, cerebral cortex, and blood lymphocytes. There were statistically significant differences in COX-1, COX-2, and TNF-α mRNA and protein expression in the hippocampus and cerebral cortex, with significant differences in COX-2 and TNF-α in the lymphocytes. …”
Get full text

Impact of the severe acute respiratory syndrome coronavirus 2 pandemic on the incidence of type 1 diabetes mellitus in children in Yamanashi, Japan by Tomohiro Saito, Mie Mochizuki, Kisho Kobayashi, Hiromune Narusawa, Daisuke Watanabe, Koichi Makino, Hideaki Yagasaki, Kazumasa Sato, Tomoaki Sano, Masanori Ohta, Hiroshi Yokomichi, Shin Amemiya, Koji Kobayashi

“…These findings suggest that there was no statistically significant change in the incidence of T1D attributable to the COVID-19 pandemic in Yamanashi Prefecture. …”
Get full text

Association of dietary decanoic acid intake with diabetes or prediabetes: an analysis from NHANES 2005–2016 by Huangxin Zhu, Huangxin Zhu, Qingan Fu, Ruxin Chen, Linfei Luo, Miao Yu, Yue Zhou

“…However, the relationship between DDA intake and the risk of prediabetes was not statistically significant in the fully adjusted model (OR = 0.95, 95% CI: 0.84–1.07, p = 0.404).ConclusionThis study found that higher DDA intake may be associated with lower prevalence of diabetes among prediabetic population, and high education level strengthen this relationship.…”
Get full text

Effect of Proinflammatory Cytokines (IL-6, TNF-α, and IL-1β) on Clinical Manifestations in Indian SLE Patients by Vinod Umare, Vandana Pradhan, Milind Nadkar, Anjali Rajadhyaksha, Manisha Patwardhan, Kanjaksha K. Ghosh, Anita H. Nadkarni

“…Mean level of TNF-α was 44.76±68.32 pg/mL for patients with active disease while it was 25.97±22.03 pg/mL for those with inactive disease and this difference was statistically significant (P=0.0161). Similar results were obtained for IL-1β (P=0.0002). …”
Get full text

The Effectiveness of &#147;Improvement of Driver-Behavior Program&#148; on Self-Control of Individuals Whose Driving Licenses Have Been Seized due to Drinking and Driving. by &Yacute;brahim Taymur, Veli Duyan, Kadir &Ouml;zdel, Ersin Budak, Buket Belk&yacute;z G&uuml;ng&ouml;r

“…Therefore, the alteration in Self-Control Scale Scores during the program was statistically not significant ( F=1,434; p=0.236).Further pair-wise comparison revealed that only the difference between the SCL scores at 6&#146;th and 12&#146;th weeks was statistically significant (p:0,005).Besides, ANCOVA analysis revealed that the age had significant effect on the difference between the SCL scores at the 6&#146;th and 12&#146;th weeks (F=3,858; p:0.027). …”
Get full text

Application of Anchoring Technique in Unilateral Percutaneous Vertebroplasty for Neurologically Intact Kümmell’s Disease by Rongqing Qin, Xing Zhang, Hongpeng Liu, Bing Zhou, Pin Zhou, Chuanliang Hu

“…Significantly statistical differences were observed in both BP-VAS and ODI scores at each time point of follow-up when compared with the preoperative condition (P<0.05). Besides, statistically significant improvement in radiographic measurements such as kyphotic angle and the height of the anterior border of the involved vertebral body between the preoperative and postoperative assessments was also observed (P<0.05) and asymptomatic leakage of cement occurred in 7 of 29 cases (24.1%). …”
Get full text

Classification of female MDD patients with and without suicidal ideation using resting-state functional magnetic resonance imaging and machine learning by Morteza Fattahi, Milad Esmaeil-Zadeh, Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Reza Rostami, Jamil Mansouri, Gholam-Ali Hossein-Zadeh, Gholam-Ali Hossein-Zadeh

“…Further analysis revealed three features that demonstrated statistically significant differences between these three, resulting in a 90.00% accuracy rate. …”
Get full text

Machine Learning for Lung Cancer Subtype Classification: Combining Clinical, Histopathological, and Biophysical Features by Aiga Andrijanova, Lasma Bugovecka, Sergejs Isajevs, Donats Erts, Uldis Malinovskis, Andis Liepins

“…<b>Results:</b> The integration of biophysical features improved classification accuracy from 86.49% to 89.19% using a data-driven Bayesian Network model, though this improvement was not statistically significant (<i>p</i> = 1.0). Four key features were identified as highly predictive: sex, vascular invasion, perineural invasion, and ALK mutation. …”
Get full text

Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials by Zanfeng Cao, Zhanzheng Yang, Zijing Liang, Qingyan Cen, Zuopeng Zhang, Hengrui Liang, Rong Liu, Liangbo Zeng, Yubao Xie, Youping Wang

“…The risk of mortality in patients who received prone position ventilation was 13% lower than for those who received supine ventilation, but this effect was not statistically significant (RR: 0.87; 95% CI: 0.75–1.00; P = 0.055). …”
Get full text

Spatial genetic characterization of the red fox (Vulpes vulpes) in the area between the Alps and the Central Dinaric Mountains by A. Devedžić, F. F. Urzi, B. Pokorny, G. Vengušt, D. Ž. Vengušt, F. Janžekovič, L. Velić, T. Eterović, B. K. Stroil, E. Bužan

“…However, it is noteworthy that statistically significant differences in estimates of genetic differentiation were only apparent when comparing the populations between the two countries. …”
Get full text

Physicians’ and patients’ perceived risks of chronic pain medication and co-medications in Quebec, Canada: a cross-sectional study by Gwenaëlle De Clifford-Faugère, Anaïs Lacasse, Hermine Lore Nguena Nguefack, Marimée Godbout-Parent, Aline Boulanger, Nancy Julien

“…For eight subclasses, the difference in the mean perceived risk score was > 2 points and statistically significant (p < 0.05): non-specific oral NSAIDs, acetaminophen in combination with an opioid, short-acting opioids, long-acting opioids, tricyclic antidepressants, antipsychotics, benzodiazepines, and medical cannabis. …”
Get full text

Prevalence of Dental Caries in Schoolchildren from the Galapagos Islands: ESSO-Gal Cohort Report by Ana Armas-Vega, Juan Marcos Parise-Vasco, María Cristina Díaz-Segovia, David Alejandro Arroyo-Bonilla, María José Cabrera-Dávila, María Christel Zambrano-Bonilla, Ingrid Ordonez-Romero, Andrea Caiza-Rennella, Andrea Zambrano-Mendoza, Celia Ponce-Faula, Andrés Viteri-García

“…The caries prevalence rates based on ICDAS II codes 1–6, 1–2, and 3–6 were 98.01%, 96.9%, and 85%, respectively. A statistically significant difference was observed among the different islands regarding the cutoff point for ICDAS II codes 3–6 (p≤0.001). …”
Get full text

Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients by Yan Lv, Xiangying He, Eryi Zhao, Yidong Deng, Yingliu Huang, AC Chen, Shixiong Huang, Qi Qin, Tao Liu, Guoqiang Wen

“…Serum brain-derived neurotrophic factor did not show statistically significant changes during groups. Conclusion: Electroencephalogram default mode network provided a functional aspect of left vertebral artery stenting patients, and the beta-1 band power and distribution alterations could be candidate measurements for the plasticity alterations and prognosis evaluation.…”
Get full text

Advanced mandibular reconstruction with fibular free flap and alloplastic TMJ prosthesis with digital planning by Justin M. Pyne, Clayton M. Davis, Ryan Kelm, Claudine Bussolaro, Walter Dobrovolsky, Hadi Seikaly

“…There was a median perioperative MIO increase of 15.0 mm, and this was statistically significant (p  =  0.027). Conclusions This study highlights the complexities involved in mandibular reconstruction with involvement of the TMJ. …”
Get full text

Exploring Spatio-Temporal Variations in Water and Land Resources and Their Driving Mechanism Based on the Coupling Coordination Model: A Case Study in Western Jilin Province, China by Lujuan Zhang, Guzailinuer Aihemaitijiang, Zihao Wan, Mingtang Li, Jiquan Zhang, Feng Zhang, Chunli Zhao

“…The results indicate the following: (1) From a temporal perspective, the coupling coordination degree of WLR in WJP has shown a year-on-year increase from 2006 to 2020, transitioning from a moderate imbalance to intermediate coordination, reflecting a trend of continuous improvement. (2) Regarding spatial distribution, the overall center of gravity of water and land resource coupling coordination remained relatively stable between 2006 and 2020; however, the direction of distribution gradually shifted from the northeast to the southwest and then from the northwest to the southeast. (3) The AAT, PD, and RR from 2006 to 2020 were all statistically significant at <i>p</i> < 0.01. Notably, the RR positively influences the CCD of WLR, whereas the AAT and PD exert a negative impact. …”
Get full text

Effects of Different Taping Techniques in Individuals with Myofascial Pain Syndrome with a Trigger Point in the Trapezius Muscle: A Sham-controlled Randomized Study by Kubra KARDES, Pinar VAN DER VEER, Yunus Emre TUTUNEKEN, Hale Nur AYKAC, Esra ARSLAN, Aysenur AKSOY, Yasemin BURAN CIRAK

“…There was a significant difference in the pain score between the groups after treatment (p&lt;0.05). A statistically significant difference was found in the cervical flexion ROM of all groups after treatment (p&lt;0.05). …”
Get full text

Development of Korean Teaching Model for Surgical Procedures in Trauma -Essential Surgical Procedures in Trauma Course- by Hohyun Kim, Chan-Yong Park, Hyun-Min Cho, Kwang-Hee Yeo, Jae Hun Kim, Byungchul Yu, Seung-Je Go, Oh Sang Kwon

“…The differences in self-efficacy score according to career stage (<1 year, 1–3 years, 3–5 years, and >5 years) were also statistically significant (p<0.001). Conclusions The data of the ESPIT participants indicated that they felt that the ESPIT course improved their self-efficacy with regard to essential surgical procedures in trauma. …”
Get full text

Association between weight-adjusted waist index and cognitive impairment in Chinese older men: a 7-year longitudinal study by Jie Lin, Hongchen Shen, Wenjuan Yang, Guojun Zhang, Jie Sun, Wenqin Shen, Li Huang, Huajian Chen

“…After controlling for all potential confounding variables, our analysis showed a statistically significant positive association between WWI and cognitive decline. …”
Get full text

Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial by Nick Shortt, Alex Semprini, Mark Weatherall, Richard Beasley, Irene Braithwaite, Angela Liu, Melanie McConnell, Joseph Singer, Darmiga Thayabaran, Abbie Copinga, Abigail Cadwallader, Ahmad Zareh, Aidan Kortegast, Al-Sheibani Saif, Alaina van Zyl, Alex Graham, Alice Liu, Alice Manch, Alison van Wyke, Amanda Barkley, Amy Zhuang, Andrew Mcglashen, Androulla Kotrotsos, Angela Blackwood, Angeline Day-Mesuré, Annabel Turley, Anne Lim, Anne Marie-Nimmo, Anstey Harsant, Anthony Roberts, Ashley Cronin, Barbara Mcrae, Blair Finlayson, Bob Kim, Brandon, Brendon Mcintosh, Brian Johnston, Carina Soeteman, Carla Mcinness, Carrol Newman, Cassie Butler, Catherine Hosler, Cathy Hight, Chantel Kissick, Charlotte Schimanski, Chau Ly, Cheryl Mabbett, Chris Wrapson, Christy Biju, Chuck Varghese, Claire Livingston, Corry Bezems, Danielle Stewart, Daryl Sayer, David Postlewaight, Deb Lawrence, Debora Ngny, Deborah Ellison, Debra Clutterback, Delphine Destrez, Diana Montelli, Dipika Parmar, Dixie Howard, Donnie Loh, Eddie See, Elda Lubbe, Eric Li, Evan Tan, Fiona Mclachlan, Fiona Srush, Fran Chen, Garth Mitchinson, Gina Azer-Iskander, Glenn Summerville, Grace O’conner, Grant Bell, Hayley Garvin, Helen Jarvie, Henriette Meyer, Ingrid Nickson, Ingrid Reed, Irene Nicks, Jackie Jamieson, Jacqui Brus, Jacqui Craw, James Westbury, Jan Green, Janet Downing, Jayne Lewis, Jenna Ludlow, Jenni Puckley, Jennifer Gerbes, Jenny Sparks, Jenny Wu, Jess Barton, Jessica Ensor, Jilly Alexander, Jim Sherborne, Joanna Topliss, Jordan Jeffray, Jordon Hinton, Joseph Tsou, Joy Birch, Julia Mcdonald, Julie Earwaker, Julie Lamb, Julie Summers, Kadyn Lowe, Kaleigh Mackel, Karen Rich, Karen Chen, Karen Wainman, Karena Hall, Kate Adams, Kate Griffin, Kayleigh Mackel, Kelly Burgess, Kelly Harvey, Kelly Shearer, Kelsi Burns, Kerry Dean, Kerry Oxenham, Kritika Singh, Lara Blaikie, Leanne Hall, Leanne Herbert, Leanne Hosking, Leanne Steele, Leigh Vaughan, Lesley Robertson, Levi Bian, Linda Herman, Linda Joe, Linda Southby, Lisa Josephs, Lisa Mitchell, Lorina Lu, Lorraine Brunton, Lucy Armstrong, Lynda Bell, Malinda Ouk, Malli Kotali, Marcus Liddle, Margaret Helms, Marion Gray, Mark Arundel, Mark Webster, Martin Boyle, Maryanne Smyth, Mate Hegedus-Gaspar, Matthew Grey, Maureen Raju, Melanie Wong, Michelle Hwang, Michelle Nawisielski, Michelle Speirs, Natascha Roughton, Navjot Kaw, Neha Chand, Nehad Kamel, Neville Puckey, Nicholas Tee, Nimmi Gnanasekaran, Nolan Mcrae, Noor Al-Rawe, Oliver Rew, Olivia Haslam, Outi Kolju, Palak Mehta, Patrick Lim, Peter Neal, Rachael Gerretzen, Rachael Munns, Rachel Yang, Rachelle Smith, Raksha Goundar, Rav Singh, Ravniel Singh, Rebecca Coley, Rebecca Hesom, Rebekah Beard, Reece Olsen, Renee Belling, Robyn Morrison, Roseanna Mcdonald, Ruby Willing, Saif Al-Sherbeni, Sally Purdie, Sam Betty, Sam Appleford, Samantha Fordham, Samit Patel, Sara Preston, Sarah Wallace, Sascha Ion, Shahlaa Al Salih, Sharon Sullivan, Shazeel Rauf, Sheryl Montgomerie, Shilpa Narain, Shirin Namjou, Shuji Zhang, Simerjeet Singh, Sjaani Stanley, Sonia Schwaum, Steve Jo, Sultana Zannat, Tanya Baker, Tyler Pornchaisuksiri, Utsav Sharma, Vicki Douglas, Victoria Rameke, Vincent Ho, Vioky Usher, Violet Harley, Vishwatej Gangapuri, Warren Greene, Wendy Parkes, William Gia, Wilma Gordon, Yalun Weng, Yasmin Razoki, Yolanda Savage, Zheng Li

“…There were no statistically significant differences between treatments for all secondary outcome variables. …”
Get full text