Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes by Peter Vo, Denise M. Imai-Leonard, Benjamin Yang, Andrew Briere, Andy Shao, M. Isabel Casanova, David Adams, Takanori Amano, Oana Amarie, Zorana Berberovic, Lynette Bower, Robert Braun, Steve Brown, Samantha Burrill, Soo Young Cho, Sharon Clementson-Mobbs, Abigail D’Souza, Mary Dickinson, Mohammad Eskandarian, Ann M. Flenniken, Helmut Fuchs, Valerie Gailus-Durner, Jason Heaney, Yann Hérault, Martin Hrabe de Angelis, Chih-Wei Hsu, Shundan Jin, Russell Joynson, Yeon Kyung Kang, Haerim Kim, Hiroshi Masuya, Hamid Meziane, Steve Murray, Ki-Hoan Nam, Hyuna Noh, Lauryl M. J. Nutter, Marcela Palkova, Jan Prochazka, Miles Joseph Raishbrook, Fabrice Riet, Jennifer Ryan, Jason Salazar, Zachery Seavey, John Richard Seavitt, Radislav Sedlacek, Mohammed Selloum, Kyoung Yul Seo, Je Kyung Seong, Hae-Sol Shin, Toshihiko Shiroishi, Michelle Stewart, Karen Svenson, Masaru Tamura, Heather Tolentino, Uchechukwu Udensi, Sara Wells, Jacqueline White, Amelia Willett, Janine Wotton, Wolfgang Wurst, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Louise Lanoue, K. C. Kent Lloyd, Brian C. Leonard, Michel J. Roux, Colin McKerlie, Ala Moshiri

“…Methods 8,707 knockout mouse lines phenotyped by the International Mouse Phenotyping Consortium were queried for genes associated with statistically significant (P < 0.0001) abnormal cornea morphology to identify candidate CD genes. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…Results The study showed that eight weeks of supplementation with various collagen types had statistically significant effects on pain, quality of life, kinesiophobia, and foot function scale scores in patients with meniscopathy (p < 0.05). …”
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Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: a systematic revi... by Tilahun Degu Tsega, Sintayehu Simie Tsega, Asaye Alamneh Gebeyehu, Getaneh Atikilt Yemata, Rahel Mulatie Anteneh, Almaw Genet Yeshiwas, Getasew Yirdaw, Chalachew Yenew, Anley Shiferaw Enawgaw, Amare Genetu Ejigu, Ahmed Fentaw Ahmed, Zeamanuel Anteneh Yigzaw, Berhanu Abebaw Mekonnen, Meron Asmamaw Alemayehu, Abathun Temesgen, Abebaw Molla, Habitamu Mekonen, Assefa Andargie Kassa, Gashaw Melkie Bayeh

“…There was not statistically significant association of gender with viral load suppression rate of third line antiretroviral therapy. …”
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Clinical teaching practice and effect research of newly recruited nurses in the Department of Stomatology (口腔科新入职护士临床教学实践及效果研究) by LIANG Yu (梁宇), LI Jiahui (李嘉慧), CAI Shuang (蔡爽), SUO Shuai (索帅), ZHI Shengrui (只升睿), LIU Xuewei (刘学伟)

“…Results Through stratified teaching, the teaching results showed that the daily performance and examination results of nurses in the undergraduate group, the junior college group and the technical secondary school group after practice were better than those before practice, with a statistically significant difference (P＜0. 05). The performance of nurses in the undergraduate group was better than that in the junior college group and the technical secondary school group, with a statistically significant difference (P＜0. 05). …”
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Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retin... by Samir El Baha, Mahmoud Leila, Ahmed Amr, Mohamed M. A. Lolah

“…The difference in visual outcome between each study group and its respective control was statistically significant between Groups II-IIA and III-IIIA, p=0.03, but not between Groups I-IA, p=0.07. …”
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Tailored BEST Exercise Protocol in Heart Failure Rehabilitation by Kevin Triangto, Basuni Radi, Bambang Budi Siswanto, Tresia Fransiska Ulianna Tambunan, Teuku Heriansyah, Alida Rosita Harahap, Aria Kekalih, Ade Meidian Ambari, Bambang Dwiputra, Dwita Rian Desandri, Hajime Katsukawa, Anwar Santoso

“…However, the lack of statistically significant NT-proBNP reduction suggests further studies on cardiac biomarkers are needed. …”
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Behavioral risk factors and socioeconomic inequalities in ischemic heart disease mortality in the United States: A causal mediation analysis using record linkage data. by Yachen Zhu, Laura Llamosas-Falcón, William C Kerr, Jürgen Rehm, Charlotte Probst

“…In both males and females, clear socioeconomic gradients in IHD mortality were observed, with low- and middle-education people bearing statistically significantly higher risks compared to high-education people. …”
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Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke by SUN Jie, CHEN Guijuan, XU Han, ZHANG Tianyu, DING Yi, WANG Shurui, LI Li

“…Surface electromyography (sEMG) was used to measure the median frequency (MF) and integrated electromyography (iEMG) of the patients' bilateral erector spinae and multifissure muscles.ResultsBefore treatment, there was no statistically significant difference in PASS, BBS, FMA-LE, MBI scores, or bilateral erector spinae and multifidus MF and iEMG values between the two groups (<italic>P</italic>&gt;0.05). …”
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Comparative Assessment of 0.5% Levobupivacaine and 0.5% Ropivacaine for Anaesthetic Potency in Mandibular Third Molar Extractions: A Randomised Controlled Trial by Prachi Surolia, Rajanikanth Kambala, Nitin Bhola, Anchal Agarwal

“…Both Levobupivacaine and Ropivacaine showed similar efficacy in achieving the depth of anaesthesia during surgery, with no statistically significant difference observed (p=1.00). The Levobupivacaine group exhibited a longer time to rescue analgesia (656.50 minutes) compared to the Ropivacaine group (501.83 minutes), with a statistically significant difference (p=0.0001). …”
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Correlations of Cancer-Related Fatigue with Clinicopathological Features and Quality of Life in Gastric Cancer by Dong Liu, A-Dong Xia, Yue-Long Xing, Kai Zhang, Dan Chen

“…Relevant data were collected and compared. Results. Statistically significant differences were found between the two groups in age ratio (χ2=41.671, P<0.001), T stage ratio (χ2=9.973, P=0.019), N stage ratio (P<0.001), PS score (P<0.001), and the degree of gastric cancer thickening (14.21±3.32 vs. 12.12±3.81 mm, t=4.572, P<0.001). …”
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Effect of Meridian Massage combined with Swallowing Rehabilitation Training on Elderly Patients with Dysphagia after Stroke by Hui FAN, Zhongqin XU, Chunxia MA, Lei DONG, Yao ZHOU

“…Before treatment, four weeks after treatment and 12 weeks after follow-up, the Gugging swallowing screen(GUSS)was used to assess the swallowing function; the Barthel index scale was used to evaluate the activities of daily living; the incidence of aspiration and aspiration pneumonia, successful removal rate of gastric tube and indwelling time of gastric tube were compared between the two groups.Results:Before treatment, there was no significant difference in GUSS score and Barthel score between the two groups(<italic>P</italic>&gt;0.05).Compared with the control group, the GUSS score and Barthel score of the observation group after treatment for four weeks and follow-up for 12 weeks were significantly improved, and the difference was statistically significant(<italic>P</italic>&lt;0.05).Compared with the control group, the success rate of gastric tube removal in the observation group after treatment for four weeks was significantly higher and the indwelling time of gastric tube was significantly shorter, the difference was statistically significant(<italic>P</italic>&lt;0.05).There was no significant difference in the incidence of aspiration and aspiration pneumonia between the two groups(<italic>P</italic>&gt;0.05).Conclusion:Meridian massage combined with swallowing rehabilitation training can effectively improve the success rate of gastric tube removal, shorten the indwelling time of gastric tube, and improve the swallowing function and activities of daily living of elderly patients with dysphagia after stroke.…”
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Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study by Yilmaz Karaduman, Arzu Muz, Azize Serçe, Servi Yildirim, Ismail Eren Durmus, Suna Akin Takmaz

“…Increases in HHS scores and decreases in VAS values for stages 2-3 were statistically significant in both groups (p-value <0.001). …”
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Functional Near-Infrared Brain Network Characteristics Analysis in Patients with Cognitive Impairment after Stroke by JIN Tao, LI Haozheng, BAO Chunrong, ZHUANG Min, CAI Weiqiang, HU Ruiping, WU Yi

“…Compared with the normal group, there were significant differences in the strength of functional connectivity of the in the SEN and FPN regions of the HbO₂-based homologous brain network in the severe group (<italic>P</italic>&lt;0.05), but there were no significant differences in the regions of interest of the HbR-based homologous brain network in the three groups (<italic>P</italic>&gt;0.05). (3) Functional connectivity strength of heterologous brain networks: compared with the normal group, the functional connectivity of SEN-VAN, SEN-DMN, SEN-FPN, VAN-FPN and DMN-FPN in the severe group decreased significantly, and the differences were statistically significant (<italic>P</italic>&lt;0.05). Compared with the mild to moderate group, the functional connectivity of SEN-DAN and SEN-FPN in the severe group decreased significantly, and the differences were statistically significant (<italic>P</italic>&lt;0.05). …”
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Role of Sling Tuina Exercise Technique in Improving Paraspinal Muscle Asymmetry in Patients with Adolescent Idiopathic Scoliosis by LIU Min, MA Zhaoshui, XU Qiangqiang, LI Li

“…The intra-group comparison results showed that the improvement of PMSI value and Cobb's angle in the experimental group was better than that in the control group after treatment, and the PMSI value was closer to 1 in the experimental group (<italic>P</italic>&lt;0.05), and the Cobb's angle was significantly lower (<italic>P</italic>&lt;0.05); however, there was no statistically significant difference of the ATR value between the two groups after treatment (<italic>P</italic>&gt;0.05).Conclusiontechnique of sling exercise with Tuina therapy can effectively improve the asymmetry of paravertebral muscles and achieve the orthopedic purpose of reducing the Cobb's angle and trunk rotation angle of patients, which is recommended for clinical application.…”
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Prospective multi-centre analysis of rural trauma team development training for medical trainees and traffic law enforcement professionals in Uganda: an interrupted time series stu... by Herman Lule, Micheal Mugerwa, Robinson Ssebuufu, Patrick Kyamanywa, Jussi P. Posti, Michael Lowery Wilson

“…The median MCQ scores (IQR) were compared before and after training at 95% CI, regarding p < 0.05 as statistically significant. Triangulation with open-ended questions was obtained. …”
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Clinical Efficacy of Cervical Core Strengthening Exercise in the Treatment of Cervicogenic Headache by PEI Qian, GUO Xianfeng, HUANG Qiang

“…Specifically, at 3 months of treatment, the scores of the treatment group were VAS (2.96±1.11), HAMD-17 (25.95±5.91), PSQI (4.55±0.81), and PGIC (4.87±1.47), while the scores of the control group were VAS (5.86±1.31), HAMD-17 (36.97±7.62), PSQI (6.97±1.21), and PGIC (2.36±0.74), and the difference was statistically significant respectively (<italic>P</italic>&lt;0.05). …”
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Hemodynamics Change and Clinical Efficacy on Cervical Spondylosis of Vertebral Artery Type Treated by Hot Compress Therapy with Medicinal Salt Pillow by Li CHEN, Lijun YAO, Li ZHAO, Chunqiao FU, Xiaoyu XU

“…The ESCV scores were both improved after treatment for the two groups (<italic>P</italic>&lt; 0.05), with the scores of observation group (23.13±3.15) higher than the control group (21.73±3.39), however, the difference was not statistically significant (<italic>P</italic>&gt; 0.05). There was no statistically significant difference of clinical efficacy between the two groups (<italic>P</italic>&gt; 0.05), and no adverse reactions were observed in either groups.Conclusion:The effect of hot compress therapy with medicinal pillow filled with salt can significantly improve the blood flow of bilateral vertebro-basilar artery, effectively relieve the symptoms of cervical spondylosis of vertebral artery type and improve the function of cervical vertebra.…”
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Structure of mycoses of the skin and its appendices in HIV-infected patients by V.D. Moskaliuk, I.I. Kravchuk, Yu.O. Randiuk, I.V. Balaniuk

“…In the absence of antiretroviral therapy, a statistically significant direct relationship was established between the presence of fungal lesions of the skin and its appendages and indicators of HIV load in the blood, as well as the duration of HIV infection.…”
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Prevalence and Determinants of Diarrheal Diseases among Under-Five Children in Horo Guduru Wollega Zone, Oromia Region, Western Ethiopia: A Community-Based Cross-Sectional Study by Kefalew Alemayehu, Lemessa Oljira, Melake Demena, Abdi Birhanu, Dasselegn Workineh

“…A P value of ≤0.05 was considered statistically significant Results. The prevalence of diarrhea among under-five children was 149 (24%) (95% CI: 20.8, 27.3). …”
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Factors influencing preformed metal crowns and prefabricated zirconia crowns by Shuman Deng, Weiwei Dou, Ying Chen, Zhixiao Chen, Ning Song, Qi Gao, Li Zhang, Jing Xie

“…In terms of discomfort symptoms, 105 (76.7%) and 102 (76.1%) cases were reported after PMC and ZC placement respectively; however, there was no statistically significant difference between the two groups (P > 0.05). …”
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