A generic and dynamic measure of health-related quality of life across a variety of health and disease conditions: insights from healthy individuals and patients with a variety of... by Mohamad Adam Bujang, Wei Hong Lai, Xun Ting Tiong, Alex Ren Jye Kim, Masliyana Husin, Yvonne Yih Huan Jee, Nurul Fatma Diyana Ahmad, Clare Hui Hong Tan, Khoo Sing Yee, Yoon Khee Hon, Cheng Hoon Chew, Eileen Pin Pin Yap, Fazalena Johari, Alan Yean Yip Fong

“…Results Comparisons between healthy and non-healthy participants revealed statistically significant differences (p < 0.001) in the mean overall HRQOL score as well as across all its nine domains. …”
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Comparative Analysis of the Marginal Fit and Internal Adaptation of CAD-CAM-Fabricated Versus Conventionally Fabricated Ceramic Crowns: A Systematic Review by Mohammed Ibrahim Mathar

“…Overall, CAD-CAM-fabricated crowns exhibited smaller marginal discrepancies and better internal adaptation, although the differences were not statistically significant. The findings suggest that CAD-CAM technology may improve the fit of ceramic crowns and FDPs, but variations in study outcomes emphasize the impact of factors like material choice and fabrication methods.…”
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Collagen Fibril Diameter in Relation to Bone Site and to Calcium/Phosphorus Ratio by Panagiotis Berillis, Dimitris Emfietzoglou, Margaret Tzaphlidou

“…In most cases, statistically significant differences in mean fibril diameter values between different bone sites were detected. …”
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Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment by Zhan Zhang, Xiaonan Zong, Zhaohui Liu, Xiaoyu Dong, Huihui Bai, Linyuan Fan, Ting Li

“…Notably, the lowest alpha diversity was recorded six months to one year after initiating anti-tuberculosis treatment, with this decline being statistically significant (P = 0.023). The dominance of Lactobacillus iners in the vaginal microbiota was more common in women with genital tuberculosis than that of Lactobacillus crispatus. …”
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The Relationship Between Serum Levels of Total IgE, IL-18, IL-12, IFN-<mml:math> <mml:mi>&#x03B3;</mml:mi> </mml:math> and Disease Severity in Children With Atopic Dermatitis

“…There was no statistically significant difference between patients and controls in respect of serum levels of IL-12/p40 <mml:math> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mn>.227</mml:mn> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:math>. …”
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Effect of Extracorporeal Shock Wave combined with Occupational Therapy on Forearm Pronation Disorder in Children with Spastic Cerebral Palsy by Hezeng LIU, Yong ZHAO, Bingxu JIN, Chuntao ZHANG, Yang YANG, Miaotao WU, Xiaoli WANG, Jixiang CHENG

“…Objective:To observe the effect of extracorporeal shock wave combined with occupational therapy therapy on forearm pronation disorder in children with spastic cerebral palsy(SCP).Methods:A total of 42 children with SCP were randomly divided into the control group and the observation group, with 21 cases in each group in the children rehabilitation department of the affiliated Nanhai maternity and children's Hospital of Guangzhou university of traditional Chinese medicine from January to December 2019.The control group was given targeted occupational therapy, including upper limb forearm pronator stretching therapy, neurophysiological therapy(Bobath technology), proprioceptive neuromuscular facilitation therapy(PNF); game type occupational training including placing objects in forearm supination position, supination grasping stick, supination fetching game, palm and back game, etc..The above training was conducted once a day, 30 minutes per time, six times a week, three months as a course of treatment, continuous treatment for two courses.The observation group was given extracorporeal shock wave therapy on the basis of the control group.The child with SCP was in a comfortable position and the forearms of the upper limbs were placed on the plane so that it could free its own gravity.The abdomen of pronator teres muscle was impacted with the probe of shock wave therapeutic instrument(pressure intensity: 1.0-1.5 bar;frequency: 8-10 Hz;impact times: 1 000-2 000 times).Three to five minutes each time, once every three days, twice a week, three months as a course of treatment, continuous treatment for two courses.Before treatment, after treatment for three months and six months, the modified Ashworth scale(MAS)was used to evaluate the spasticity of forearm pronator muscles;the active range of motion(AROM)of forearm supination was measured by joint range of motion protractor;and the fine motor quotient(FMQ)of hands was evaluated by Peabody development motor scale-fine motor(PDMS-FM).Results:Before treatment, there was no significant difference in MAS score, AROM angle and FMQ score between two groups(<italic>P</italic>&gt;0.05).Compared with before treatment, the MAS scores of the two groups decreased significantly after treatment for three and six months, and the AROM angle and FMQ score increased significantly, the difference was statistically significant(<italic>P</italic>&lt;0.05).Compared with the control group at the same time after treatment, MAS score of the observation group was significantly lower, AROM angle and FMQ score were significantly higher, the difference was statistically significant(<italic>P</italic>&lt;0.05).Conclusion:Extracorporeal shock wave combined with occupational therapy therapy can effectively improve the degree of upper limb spasticity and forearm supination joint activity in children with spastic cerebral palsy, and improve the fine motor function of hands.…”
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Association between some environmental risk factors and attention-deficit hyperactivity disorder among children in Egypt: a case-control study by Riham Abdelhamid Hussein, Rania Hussein Refai, Aleya Hanafy El-zoka, Hanan Galal Azouz, Mohamed Fakhry Hussein

“…The mean ± SD hair lead level in ADHD children was 2.58 ± 1.95, while in controls was 1.87 ± 0.92, with a statistically significant difference (p < 0.001). The mean ± SD hair manganese level in ADHD children was 2.10 ± 1.54, while in controls was 1.11 ± 0.69, with a statistically significant difference (p < 0.001). …”
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Comparative effects of methamphetamine, cannabis, and polysubstance use on oral health by Osman Hasan Tahsin Kılıç, Duygu Kürklü Arpaçay, Onur Çağdaş Gezen, Zehra Nur Bayram, Aysel Başer

“…A p-value of &lt; 0.05 was considered statistically significant.ResultsThe study revealed significant differences in oral health among substance users compared to the control group. …”
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Work loss in patients with rheumatoid arthritis treated with abatacept, rituximab, tocilizumab or TNF inhibitors: a nationwide direct drug-to-drug comparison by Ulf Lindström, Johan Askling, Katerina Chatzidionysiou, Lotta Ljung, Lars Klareskog, Martin Neovius, Nils Feltelius, Eva Baecklund, Christopher Sjöwall, Helena Forsblad-d’Elia, Carl Turesson, Elisabet Lindqvist, Thomas Frisell, Alf Kastbom, Helena Forsblad-d'Elia, Jonas Söderling, Ann Knight, Gerd-Marie Alenius, Gustaf Magnus Bruze

“…Following IPTW, at 3 years before starting the treatment, there were no statistically significant differences in the mean annual adjusted work loss days between rituximab, abatacept or tocilizumab vs TNFi (mean difference vs TNFi: rituximab 1.1 days, 95% CI −4.5 to 6.7; abatacept 3.3, 95% CI −2.6 to 9.2; tocilizumab 1.2, 95% CI −4.9 to 7.3). …”
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Does providing atrial fibrillation patients, after pulmonary vein isolation, with a 1-lead ECG device relieve the emergency department?-A historically controlled prospective trial. by Jasper L Selder, Mark J Mulder, Willem R van de Vijver, Philip M Croon, Leontine E Wentrup, Stéphanie L van der Pas, Jos W R Twisk, Igor I Tulevski, Albert C Van Rossum, Cornelis P Allaart

“…<h4>Conclusion</h4>Providing patients with AF following PVI with a 1-lead ECG device did not result in a statistically significant reduction in ED visits during the first year. …”
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Exploring Motor Recovery Differences in Paretic Upper and Lower Extremity after Stroke: A Cross-sectional Analytical Study by Rathinasabapathy Sampath Pulimoot, CKV Bhuvaneswari, Annadurai Kabilan

“…Gender differences were statistically significant for lower-limb recovery (p-value =0.024), with males showing a mean score of 24.73±5.59, indicating greater recovery. …”
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The Effectiveness of Mindfulness-Based Stress Reduction Therapy on Disease signs and Symptoms and Psychological Distress in Women with Oral Lichen Planus by Fatemeh Sarebannezhad, Abdollah Omidi, Zahra Zanjani, Elaheh Ghasemzadeh Hoseini, Narges Gholizadeh

“…The mean intensity of pain or burning sensation in the experimental group during the post-test phase was 2.94±1.85, compared to 3.65±1.69 in the control group; however, this difference was not statistically significant. Similarly, there was no statistically significant difference in the frequency of lesions between the experimental and control groups (P>0.05). …”
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Level of physical activity of students from the police force academy in Bratislava by Gabriel Bujdos, Štefan Adamčák, Michal Marko, Anna Kozaňáková

“…Moderate intensity physical activity difference was even bigger (23,09 minutes a week) in favour of male students, these results have proven to be also statistically significant at the level of significance p < 0.01. …”
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Investigation of the Influence of Deletional and Non-Deletional Hemoglobin H Disease on Pregnancy Outcomes by Zhao KS, Pan QA, Yang HY, Su JY, Deng L

“…Moreover, the deletional group exhibited a significantly lower mean corpuscular volume (MCV) during early and late pregnancy and mean corpuscular hemoglobin (MCH) during late pregnancy, with statistically significant differences (p< 0.05) compared to the non-deletional group. …”
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Lasater clinical judgment rubric in nursing education: a Turkish validity and reliability study by Esra Sezer, Hilal Yıldız Çelik, Ükke Karabacak, Kathie Lasater

“…The intraclass correlation coefficient values ranged between 0.70 and 0.90 and were statistically significant for all the items. The Cronbach’s alpha value of the rubric was 0.91 and ranged between 0.80 and 0.84 in its subdimensions. …”
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p16 expression in patient with Loop Electrosurgical Excision Procedure (LEEP) by Putu Erika Paskarani, I Gede Sastra Winata, Elisa Laura Oktrinita Sitohang, Felyanto Felyanto, Sang Ayu Putu Yuliantini

“…Meanwhile, a statistically significant association was found between p16 expression and histopathologic diagnostic (p = 0.02, 95% CI 1.4 – 38.3). …”
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Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells by Burak Durmaz, Latife Merve Oktay Çelebi, Ayşe Çekin, Ayshan Ahadova, Nur Selvi Günel, Hatice Kalkan Yıldırım, Ali Mert Özgönül, Eser Yıldırım Sözmen

“…When we compared the healthy cell lines to cancer cell lines, a statistically significant increase in caspase-3 (3.62-fold) and in TRAIL (4.38-fold) was observed in the SW-620 cell line after the application of propolis. …”
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The Clinical Impact of Tumor Grade Heterogeneity in Nonmuscle- invasive Urothelial Carcinoma of the Bladder by Meftun Culpan, Ferhat Keser, Ayberk İplikci, Gözde Kır, Gökhan Atış, Asif Yıldırım

“…Patients with mixed-grade tumors had worse PFS and CSS outcomes than those with low-grade tumors (199.84±23.22 vs. 214.94±15.92 for PFS and 202.07±19.86 vs. 233.61±9.84 for CSS, respectively) and better PFS and CSS outcomes than those with highgrade tumors (199.84±23.22 vs. 163.28±16.18 for PFS and 202.07±19.86 vs. 180.81±15.89 for CSS, respectively), although these comparisons were not statistically significant. Conclusions: Patients with mixed-grade tumors had worse PFS and CSS outcomes than patients with low-grade tumors and better PFS and CSS outcomes than patients with high-grade tumors, although these comparisons were not statistically significant. …”
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Level of Satisfaction Among Patients Using Insulin Administered by Pen vs Vial/Syringe. An Observational Prospective Study by Valladales-Restrepo LF, Delgado-Araujo AC, Oyuela-Gutiérrez MC, Ospina-Arzuaga HD, Machado-Alba JE

“…The mean DTSQ-s score was 26.6± 5.3 points, and 38.7% presented high satisfaction, without statistically significant differences between pen and vial/syringe. …”
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Effect of Cross-Sectional Designs of Different Ni-Ti Files on Shaping Ability After Repeated Usage in Simulated Root Canals. by Fikrat Shawqi Qaddori, Raid Fahim Salman

“…Results: In the first, second, third, and fourth variables a statistically non-significant difference (P > 0.05) was found between One curve and 2Shape, a statistically significant difference (P < 0.05) was found between One Curve, K3-i File, E3 Azure, and Neolix. …”
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