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Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins
Published 2025-01-01Subjects: “…Statin…”
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Inflammatory Bowel Disease and Statins
Published 2020-04-01Subjects: “…statins…”
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Statins as Modulators of Regulatory T-Cell Biology
Published 2013-01-01“…Statins are pharmacological inhibitors of the activity of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR), an enzyme responsible for the synthesis of cholesterol. …”
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GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study
Published 2025-02-01Subjects: “…Statins…”
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Challenges in Treating Statin-Associated Necrotizing Myopathy
Published 2021-01-01“…Myalgia and mild elevation in muscle enzymes are common side effects of statin therapy. While these symptoms are generally self-limited, in rare cases, statin use is associated with an immune-mediated necrotizing myopathy caused by development of autoantibodies against HMG-CoA reductase. …”
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Statins for Renal Patients: A Fiddler on the Roof?
Published 2012-01-01“…Consequently, the use of statins in the general population with dyslipidaemia is not controversial. …”
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Statins in Asthma: Potential Beneficial Effects and Limitations
Published 2015-01-01“…In light of this, this review analyzes the ways by which statins could benefit in asthma via their pleiotropic anti-inflammatory properties and explain some of the queries raised in the previous studies and provide recommendations for future studies in this field.…”
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Contribution of Statins towards Periodontal Treatment: A Review
Published 2019-01-01“…Herein, the adjunctive use of statins in periodontal therapy in vitro, in vivo, and in clinical trials was reviewed. …”
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Monacolin K as a Natural Alternative for Synthetic Statins
Published 2025-01-01“…Summary: Monacolin K is considered to be natural statin contained in fermented red rice or oyster mushroom. …”
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An Overview of the Impact of Statin Therapy on Cardiac Incident Risk
Published 2025-02-01Subjects: Get full text
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A Meta-Analysis of Statin Use and Risk of Hepatocellular Carcinoma
Published 2022-01-01“…Background. The use of statins is a potential protective factor against the development of hepatocellular carcinoma. …”
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Unveiling the Antibacterial Properties of Statins: An In Vitro Study on Helicobacter pylori
Published 2024-01-01“…This in vitro study investigated the direct antibacterial effects of three clinically approved statins, simvastatin, atorvastatin, and rosuvastatin, against H. pylori isolates. …”
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A Case of Recalcitrant Plantar Warts Associated with Statin Use
Published 2015-01-01“…Following a patient initiated decision to discontinue their statin medication, we observed rapid clearance of plantar warts without change to standard therapy or their environment. …”
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A Systematic Review Uncovering Modifiable Influences on Statin Adherence
Published 2025-01-01“…This study combines findings from previous studies to understand why many people do not take statins as prescribed.Common barriers to taking statins included not thinking being at risk of strokes and heart attacks, believing statins are harmful, experiencing side effects and poor communication and trust with healthcare professionals.Common things encouraging statin taking included thinking statins have benefits, having cholesterol levels checked, routines and methods to remember statin intake and having ways of dealing with side effects. …”
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Statin Improves Flow-Mediated Vasodilation in Chronic Kidney Diseases
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The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published 2021-01-01“…Guidelines recommend that subjects with high and very high ASCVD risk should be treated with high-intensity statins or a combination of high-intensity statins and ezetimibe. …”
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Expanding perspectives on the relationship between statin potency and lipophilicity in Alzheimer's disease management
Published 2025-02-01Subjects: “…Statin…”
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The efficacy and safety of peroperative statin treatment during coronary artery bypass grafting
Published 2018-03-01Subjects: Get full text
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Impact of Chronic Statins Use on the Development of Esophagitis in Patients with Gastroesophageal Reflux Disease
Published 2019-01-01“…We aimed to assess whether chronic statins used (> 6 months) were protective of the development of esophagitis in patients with gastroesophageal reflux disease. …”
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