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121
Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture
Published 2013-01-01“…The present study provides insight into the function of CD133 during angiogenesis as well as an explanation for the antiangiogenic effect of statins.…”
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122
The Key to Unlocking the Chemotherapeutic Potential of PPARγ Ligands: Having the Right Combination
Published 2012-01-01“…In spite of this, several groups reported exciting results with therapeutic regimens that combine PPARγ ligands with other compounds: chemotherapeutic agents, retinoid x receptor (RXR)α agonists, statins, or cell-to-cell signaling molecules in preclinical cancer models and human trials. …”
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123
Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue
Published 2018-01-01“…We revised the effects, and underlying mechanisms, of the current approved drugs for dyslipidemia and obesity (fibrates, statins, niacin, resins, ezetimibe, and orlistat; sibutramine; and diethylpropion, phentermine/topiramate, bupropion and naltrexone, and liraglutide) on adipose tissue. …”
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124
Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy
Published 2025-01-01“…Results Germline and somatic mutations mediate the onset and development of CCM through several molecular pathways. Medications such as statins, fasudil, rapamycin, and propranolol can alleviate CCM symptoms or hinder its progression by specifically modulating the corresponding targets. …”
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125
Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Immune-Mediated Necrotizing Myopathy following mRNA SARS-CoV-2 Vaccination
Published 2023-01-01“…The diagnosis of probable post-vaccination IMNM was made due to the absence of other factors that may have led to the development of autoantibodies (medicines; e.g., statins, drugs) and the temporal relationship between exposure and event. …”
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126
Anti-Hyperlipidemic Effect of Zinc complex of Betulinic acid in High Fat Diet- Induced Hyperlipidemia
Published 2023-04-01“…Drugs of first choice, Statins, despite being well tolerable, are accompanied by many adverse effects. …”
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127
Stroke Prevention: Managing Modifiable Risk Factors
Published 2012-01-01“…The use of antiplatelets and statins has been shown to reduce the risk of recurrent stroke and other vascular events. …”
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128
Current Controversies in the Prediction, Diagnosis, and Management of Cerebral Vasospasm: Where Do We Stand?
Published 2013-01-01“…Finally, the recent literature regarding interventions for the prophylaxis and treatment of vasospasm, including hyperdynamic therapy, albumin, calcium channel agonists, statins, magnesium sulfate, and endothelin antagonists is summarized. …”
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129
Telomere Biology: Key to unlocking the fountain of youth…A Systematic Review.
Published 2024-11-01“…As the role of telomere biology is well established in ageing,current research therefore aims to develop means to reduce telomere attrition,thereby reducing ageing & age related diseases.This review will focus on summarising the role of telomere biology in ageing & age related diseases while highlighting the recent advances in research aiming towards enhanced longevity & healthy ageing.This review will further emphasize on telomere targetted therapeutics such as telomerase activators & tankyrase inhibitors while also highlighting the role of antioxidative & antiinflammatory agents alongwith indirectly related approaches such as statins.…”
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130
The Story of CD4+CD28− T Cells Revisited: Solved or Still Ongoing?
Published 2015-01-01“…So far it has been shown that treatment with TNF-α blockers, abatacept, statins, and polyclonal antilymphocyte globulins (ATG) mediates reduction of the CD4+CD28− T cell level. …”
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131
Atorvastatin-Diltiazem Combination Induced Rhabdomyolysis Leading to Diagnosis of Hypothyroidism
Published 2017-01-01“…Statins and hypothyroidism, independently, can rarely cause rhabdomyolysis. …”
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132
The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease
Published 2015-01-01“…Current data suggests that statins might have beneficial effects on renal outcomes. …”
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133
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study
Published 2025-01-01“…Female sex, age > 50 years, and hypertension were associated with worse outcomes, and statins or ACE inhibitors with better outcomes.…”
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134
Anti-inflammatory and immunomodulatory effects of rosuvastatin in patients with low-to-moderate cardiovascular risk
Published 2022-06-01“…Statins have shown anti-inflammatory pleiotropic effects in subjects with/at risk of cardiovascular disease. …”
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135
Treatment advances in Vitiligo: An Updated Review
Published 2025-01-01“…A comprehensive search of the literature was carried out through the PubMed electronic database from inception to 31 December 2023 using the following search terms “vitiligo” AND “JAK inhibitors”, “vitiligo” AND “prostaglandin”, “vitiligo” AND “afamelanotide”, “vitiligo” AND “antioxidants”, “vitiligo” AND “vitamin D3”, “vitiligo AND “statins”, “vitiligo” AND “TNF-alpha”, “vitiligo” AND “interleukin”, “vitiligo” AND “light therapy”. …”
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136
Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future
Published 2015-01-01“…Other drugs have been studied such as metformin, ursodeoxycholic acid, statins, pentoxiphylline, and orlistat with only partially positive results. …”
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137
Features of conservative therapy of benign prostatic hyperplasia in patients with metabolic syndrome: " Treat to Target "
Published 2020-12-01“…The use of combination therapy with metformin, ACE inhibitors / ARA and statins in combination with tamsulosin showed efficacy after 6 and 12 months of the study compared with tamsulosin monotherapy. …”
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138
Burden of Coronary Artery Disease and Peripheral Artery Disease: A Literature Review
Published 2019-01-01“…Use of medication to control modifiable CV risk factors was variable by country (lower in France than in Canada); statins and aspirin were the most widely used therapies in patients with chronic disease. …”
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139
Coronary Artery Spasm: New Insights
Published 2020-01-01“…However, the prevalence of CAS tends to decrease in correlation with the increasing use of medicines such as calcium channel blockers, angiotensin converting enzyme inhibitor, and statins, the controlling management of atherosclerotic risk factors, and the decreased habitude to perform a functional reactivity test in highly active cardiac catheterization centers. …”
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140
Outcomes of Hospitalized COVID-19 Patients by Risk Factors: Results from a United States Hospital Claims Database
Published 2020-09-01“…Patients with hypertension (OR 0.77, 95% CI, 0.70–0.86; P < 0.001) and those administered statins were less likely to die (OR 0.54, 95% CI, 0.49–0.60; P < 0.001). …”
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