Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy by Nathan G. DeRon, Francis Fischer, Dylan Lopez, Elizabeth C. Brewer

“…Clinicians should also be aware that statin-induced myopathy can occur at any time during statin therapy. …”
Get full text

Statins and the incidence of post-stroke depression: a systematic review and meta-analysis by Chaohua Cui, Jue Li, Weicong Chen

Subjects: Get full text

Markers of inflammation before and after coronary artery bypass grafting and the effectiveness of statins by O.J. Zharinov, O.A. Yepanchintseva, I.V. Shklianka, A.I. Kurchenko, B.M. Todurov

“…The use of statins before and after revascularization surgery reduces the risk of acute coronary syndrome and the level of perioperative mortality by 30–42 %, and is effective for the prevention of complications within one year after CABG surgery.…”
Get full text

Protocol for a systematic review and meta-analysis of the combination of ezetimibe and statins for hyperlipidemia. by Tianfu Yang, Weijuan Li, Weiwei Chen, Donghong Zhu, Yuxi Ren, Xiongfeng Huang

“…<h4>Introduction</h4>Hyperlipidemia is increasingly recognized as a significant global health issue, often associated with conditions such as hypertension, diabetes, and obesity. While statins are frequently prescribed to manage lipid levels, recent studies indicate that reliance solely on statin therapy may present certain disadvantages, including prolonged treatment durations, the potential for drug resistance, and various adverse effects. …”
Get full text

Is ChatGPT an Accurate and Reliable Source of Information for Patients with Vaccine and Statin Hesitancy? by Cundullah TORUN, Abdurrahman SARMIS, Aytekin OGUZ

“…The mean scores of ChatGPT were 3.85+-0.34 for vaccination and 3.68+-0.35 for statin use. The mean scores of physicians were 3.73+-0.51 for vaccination and 3.58+-0.61 for statin use. …”
Get full text

Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective by Abdullah Qamar, Hammad Gul Khan, Muhammad Marghoob Khan, Muhammad Rizwan Bashir Kiani, Hina Kundi, Fareeha Mushtaq

Get full text

The protective effect and experimental research progress of pleotropic statins in intervertebral disc degeneration by Xianxu Zhang, Shicheng Li, Xin Liu, Zhong Ma, Qiang Zhang, Yuji Zhang, Jiangdong An, Zhiqiang Luo

Subjects: Get full text

Association between statin administration and outcome in patients with sepsis: A retrospective study by Zhou Jianzhu, Feng Zeying, Qiu Hui, Li Tong, Huang Xin, Ye Ling, Huang Longjian, Guo Chengjun, Guo Chengxian, He Li

Subjects: Get full text

Statin-Associated Necrotizing Autoimmune Myositis Complicated by an Uncommon Adverse Effect to Treatment by Brian M. Fung, Emil R. Heinze, Andrew L. Wong

“…Unlike self-limited statin myopathy, this condition usually requires aggressive immunomodulation therapy to assist recovery and prevent future disability. …”
Get full text

&beta;-Caryophyllene and Statins in Bone Fracture Healing &ndash; A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…Both BCP and statins have shown promising results in preclinical studies, enhancing bone density and promoting fracture healing. …”
Get full text

Statin prescriptions and progression of advanced fibrosis risk in primary care patients with MASLD by Andrew D Schreiner, William P Moran, Jingwen Zhang, Patrick D Mauldin, Justin Marsden, Mulugeta Gebregziabher, Chelsey A Petz, David G Koch, Chloe Bays

“…In the adjusted Cox model with statin prescription as the primary exposure, statins were associated with a lower risk (HR 0.60; 95% CI 0.45 to 0.80) of progressing to a FIB-4≥2.67. …”
Get full text

Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review by Magdalena Maria Pietrzko, Maciej Pietrzko, Wojciech Niemczyk, Dariusz Skaba, Rafał Wiench

“…In recent years, studies have emerged suggesting additional clinical benefits from the use of statins as an adjunct to classical periodontal disease treatment. …”
Get full text

Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures by Stolarczyk Mariusz, Apola Anna, Maślanka Anna, Kwiecień Anna, Opoka Włodzimierz

“…Applicability of derivative spectrophotometry for the determination of valsartan in the presence of a substance from the group of statins was checked. The obtained results indicate that the proposed method may be effective by using appropriate derivatives: for valsartan and fluvastatin - D1, D2 and D3, for valsartan and pravastatin - D1 and D3, for valsartan and atorvastatin - D2 and D3. …”
Get full text

Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner by &#xC9;ric Toussirot, Fabrice Michel, Nicolas Meneveau

Get full text

Association of Statin, Metformin, and Aspirin Use With Hepatocellular Carcinoma in the All of Us Research Program by Erik Almazan, Raymond T. Chung

Get full text

Correspondence on 'Is ChatGPT an Accurate and Reliable Source of Information for Patients with Vaccine and Statin Hesitancy?' by Hinpetch DAUNGSUPAWONG, Viroj WIWANITKIT

Subjects: Get full text

Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models by Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt

“…Emerging data suggest that manipulation of cholesterol may enhance some aspects of antitumor immunity.Methods We used syngeneic murine models (mouse oral cancer, MOC1 and TC-1) to investigate our hypothesis that a subset of statin drugs would enhance antitumor immunity and delay tumor growth.Results Using an ex vivo coculture assay of murine cancer cells and tumor infiltrating lymphocytes, we discovered that all seven statin drugs inhibited tumor cell proliferation. …”
Get full text

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

“…Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). Statins through their pleiotropic properties may modify inflammation, lipid profile, and cardiovascular outcomes in OSA. …”
Get full text

Statins Increase the Frequency of Circulating CD4+FOXP3+ Regulatory T Cells in Healthy Individuals by Ana Lucía Rodríguez-Perea, Carlos J. Montoya, Sven Olek, Claire A. Chougnet, Paula A. Velilla

“…Statins have been shown to modulate the number and the suppressive function of CD4+FOXP3+ T cells (Treg) in inflammatory conditions. …”
Get full text

Integrated Antihypertensive and Statin Treatment Protocols for Cardiovascular Disease Prevention in Low- and Middle-Income Countries by Andrew E. Moran, Obehi Aimiosior, Reena Gupta, Anupam Pathni, Swagata Kumar Sahoo, Girma Dessie, Kufor Osi, Xiulei Zhang, Bolanle Banigbe, Renu Garg, Thomas R. Frieden

Subjects: Get full text