Investigating causal relationships between entrepreneurial education and sustainable employment generation in Islamic Azad Universities in Tehran by Sana Abdulali, Mohammad Naghi Imani GelepordesariI, Asghar Sharifi

“…The findings of the research showed that according to the values ​​of the standard coefficients and the significant coefficients of T (above 2.58), it can be said that there are direct relationships between the factors. …”
Get full text

600 meters to VO2max: Predicting Cardiorespiratory Fitness with an Uphill Run by Kübra Stoican, Regina Oeschger

“…Regarding the performance of VO2max estimation, the MLR model achieved an R2 of 0.77 with a standard error of the estimate (SEE) of 3.4 mL·kg-1·min-1, the XGBoost model an R2 of 0.82 with a SEE of 3.0 mL·kg-1·min-1, and the MLP model an R2 of 0.94 with a SEE of 1.6 mL·kg-1·min-1. …”
Get full text

Factors associated with breast lymphedema after adjuvant radiation therapy in women undergoing breast conservation therapy by Summer Sami Yono, Cara Cannella, Madeleine Gonte, Sanjay Rama, Simeng Zhu, Jenna Luker, Maristella S. Evangelista, Jessica Bensenhaver, Eleanor M. Walker, Dunya Atisha

“…Results: A total of 1052 patients were included in the study: 99 (9.6 %) developed BL and 953 (90.6 %) did not develop BL. The mean ± standard deviation age was 62.9 ± 11.1 years and the mean breast volume was 1352.0 ± 744.9 cm3. …”
Get full text

Risk Communication and Community Engagement (RCCE) implementations to control cholera outbreak in Oromia region, Ethiopia by Dabesa Gobena, Esayas Kebede Gudina, Getahun Fetensa, Tizta Tilahun Degfie, Tessema Debela, Afework Tamiru, Zenebu Begna Bayissa, Dereje Diriba, Tarekegn Sarbessa, Daniel Bekele, Natinel Teferi, Achalu Layesa, Abate Zewdie, Dawit Worku Ayele, Meron Debebe Mersha, Chala Bafikadu, Senahara Korsa Wake, Lemi Abebe, Tesfaye Kebebew, Tefera Goshu, Birhanu Kenate, Yadeta Dessie, Zeleke Mekonnen

“…Risk Communication and Community Engagement (RCCE) activities were assessed using standard questionnaires adapted from national cholera guideline later categorized as poor, satisfactory and good. …”
Get full text

Meta-analyses of the effects of high-intensity interval training in elite athletes—part I: mean effects on various performance measures by Hans-Peter Wiesinger, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Thomas Leonard Stöggl, Thomas Leonard Stöggl, Nils Haller, Nils Haller, Julia Blumkaitis, Tilmann Strepp, Francesca Kilzer, Anna Schmuttermair, Will G. Hopkins

“…The heterogeneity of HIIT effects within a given type of setting varied from small to moderate (standard deviations of 1.1%–2.3%) and reduced the evidence of benefit in some settings.ConclusionAlthough athletes in some settings can be confident of the beneficial effects of HIIT on some measures related to competition performance, further research is needed. …”
Get full text

Evaluating the Effectiveness of Cyclin-Dependent Kinase 4/6 Inhibitors in Early- and Very Early-Onset Metastatic Breast Cancer: A Multicenter Study by Akif Doğan, Nurullah İlhan, Goncagül Akdağ, Sedat Yıldırım, Mustafa Seyyar, Zeynep Yüksel Yaşar, Hande Nur Erölmez, Heves Sürmeli, Buğra Öztosun, Özlem Nuray Sever, Hatice Odabaş, Mahmut Emre Yıldırım, Devrim Çabuk, Nedim Turan, Mahmut Gümüş

“…CDK4/6 inhibitors, combined with endocrine therapy (ET) have become the standard for HR+/HER2- metastatic breast cancer, yet younger patients are underrepresented in clinical trials. …”
Get full text

Accuracy of Artificial Intelligence Based Chatbots in Analyzing Orthopedic Pathologies: An Experimental Multi-Observer Analysis by Tobias Gehlen, Theresa Joost, Philipp Solbrig, Katharina Stahnke, Robert Zahn, Markus Jahn, Dominik Adl Amini, David Alexander Back

“…Based on the estimation provided by the doctors and the individual symptom checker apps, the percentage of correct diagnoses and appropriate assessments of treatment urgency was calculated in mean and standard deviation [SD] in [%]. Data were analyzed statistically for accuracy and correlation between the apps and physicians using a nonparametric Spearman’s correlation test (<i>p</i> < 0.05). …”
Get full text

CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…Viability findings were compared with colony-forming units (CFU/mL), a standard microbial viability measure.ResultsCAM/TMA-DPH staining demonstrated strong positive correlations with CFU counts across all bacterial species (r = 0.59 - 0.91), accurately reflecting biofilm vitality. …”
Get full text

Cyberinfrastructure for machine learning applications in agriculture: experiences, analysis, and vision by Lucas Waltz, Sushma Katari, Chaeun Hong, Adit Anup, Julian Colbert, Anirudh Potlapally, Taylor Dill, Canaan Porter, John Engle, John Engle, Christopher Stewart, Hari Subramoni, Scott Shearer, Raghu Machiraju, Osler Ortez, Laura Lindsey, Arnab Nandi, Sami Khanal

“…These components included (1) a UAS imagery pipeline that reduced processing time and improved image quality over standard methods, (2) a tabular data pipeline that aggregated data from multiple sources and temporal resolutions and aligned it with a common temporal resolution, (3) an approach to adapting the model architecture for a vision transformer (ViT) that incorporates agricultural domain expertise, and (4) a data visualization prototype that was used to identify outliers and improve trust in the data.DiscussionFurther work will be aimed at maturing the CI components and implementing them on high performance computing (HPC). …”
Get full text

Investigation of vitamin D deficiency in girls with growth and development variations—a single center study by Panwang Huang, Panwang Huang, Beilei Zeng, Beilei Zeng, Feng Ren, Yuan Zhou, Yuan Zhou, Ye Li, Ye Li, Yinyin Huang, Yinyin Huang, Xingyu Liu, Xingyu Liu, Jiaxiu Zhou, Jiaxiu Zhou, Yaping Ma, Yaping Ma

“…The 25(OH)D &lt;20 ng/ml was used as the standard for vitamin D deficiency.ResultsThe levels of vitamin D in the early puberty group, menarche group, obesity group, short stature group, and control group were as follows: 20.23 ± 5.90 ng/ml, 17.85 ± 5.69 ng/ml, 21.31 ± 8.99 ng/ml, 27.90 ± 12.27 ng/ml, and 29.42 ± 12.65 ng/ml, respectively. …”
Get full text

Investigating variability of craft microbreweries spent grains for classification and incorporation into precision diet formulation through multivariate analyses by Arturo Macias Franco, Aghata E.M. Silva, Tio Brody, Graham Holton, Macy Rockwell, Nelcino F. De Paula, Leilson R. Bezerra, Mozart A. Fonseca

“…Regarding gas and volatile fatty acids (VFA) production, clusters exhibited significant differences (P < 0.05) compared to an alfalfa standard, highlighting the diverse fermentation characteristics of BSG. …”
Get full text

Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…Secondary outcomes included changes in standardized measures of quality-of-life (QOL) and anxiety/depression during the 3-month follow-up. …”
Get full text

Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey by Hong-jin Liu, Yong Lin, Wang Li, Hai Yang, Wen-yue Kang, Pei-lei Guo, Xiao-hui Guo, Ning-ning Cheng, Jie-chao Tan, Yi-na He, Si-si Chen, Yan Mu, Xian-wen Liu, Hui Zhang, Mei-fang Chen

“…Methods The survey covered various aspects, including respondent demographics, the establishment and maintenance of OLV, intraoperative monitoring standards, and complications associated with OLV. Results Five hundred forty-three valid responses were collected from all provinces in mainland China. …”
Get full text

Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans by Muhammad Sadiq Khan, Ayesha Akter, Ismail Khan, Luis Carlos Ramos Aguila, Lina Akter, Mengmeng Yang, Xu Li, Yuelin Li

“…We used long-term MODIS-NDVI data (2000−2020) alongside major climatic factors to analyze greenness trends, while also utilizing Landsat data (1989–2020) to assess human-induced disturbances in the Sundarbans landscape through standard land cover monitoring techniques. The results revealed a significant annual increase in greenness (0.0021/year, p = 0.01), with a more pronounced improvement in the wet season (0.0026/year, p = 0.001) compared to the dry season (0.0016/year, p = 0.05). …”
Get full text

Multiparametric MRI and artificial intelligence in predicting and monitoring treatment response in bladder cancer by Yuki Arita, Thomas C. Kwee, Oguz Akin, Keisuke Shigeta, Ramesh Paudyal, Christian Roest, Ryo Ueda, Alfonso Lema-Dopico, Sunny Nalavenkata, Lisa Ruby, Noam Nissan, Hiromi Edo, Soichiro Yoshida, Amita Shukla-Dave, Lawrence H. Schwartz

“…The Vesical Imaging Reporting and Data System (VI-RADS), a multiparametric MRI (mpMRI)-based consensus reporting platform, allows for standardized preoperative muscle invasion assessment in BCa with proven diagnostic accuracy. …”
Get full text

c-MET-positive circulating tumor cells and cell-free DNA as independent prognostic factors in hormone receptor-positive/HER2-negative metastatic breast cancer by Jieun Park, Eun Sol Chang, Ji-Yeon Kim, Chaithanya Chelakkot, Minjung Sung, Ji-Young Song, Kyungsoo Jung, Ji Hye Lee, Jun Young Choi, Na Young Kim, Hyegyeong Lee, Mi-Ran Kang, Mi Jeong Kwon, Young Kee Shin, Yeon Hee Park, Yoon-La Choi

“…Methods Ninety-seven patients with HR+ mBC were prospectively enrolled during standard treatment at Samsung Medical Center. CTCs were isolated from blood using GenoCTC® and EpCAM or c-MET CTC isolation kits. …”
Get full text

Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Abstract Background The current standard of care (SoC) for patients with extensive-disease small-cell lung cancer (ED-SCLC) is chemo-immunotherapy. …”
Get full text

Abuse of patent rights for pharmaceuticals in wartime conditions by A.O. Kodynets, O.F. Doroshenko, I.P. Volynets, G.K. Dorozhko, V.O. Petrenko, V.V. Belitsky

“…Exclusion criteria included sources unrelated to the legal regulation of pharmaceutical patents, materials not directly connected with patent rights, and publications that did not meet scientific standards and credibility. It has been determined that patent monopolies can lead to higher drug prices, the prevention of generic drug production, import dependency, reduced competitiveness, and other consequences. …”
Get full text

Integrative computational analysis of anti-influenza potential in Caesalpinia mimosoides Lamk hydroethanolic extract by Anuwatchakij Klamrak, Shaikh Shahinur Rahman, Napapuch Nopkuesuk, Jaran Nabnueangsap, Jaraspim Narkpuk, Piyapon Janpan, Yutthakan Saengkun, Thananya Soonkum, Supawadee Sriburin, Samaporn Teeravechyan, Poramet Sitthiwong, Nisachon Jangpromma, Sirinan Kulchat, Kiattawee Choowongkomon, Rina Patramanon, Arunrat Chaveerach, Jureerut Daduang, Sakda Daduang

“…The C. mimosoides hydroethanolic extract exhibited potent antioxidant activity in the DPPH assay, with an IC50 value of 15.01 µg/mL, comparable to authentic quercetin (IC50 = 12.72 µg/mL) and approximately 4.91 times greater than standard gallic acid (IC50 = 3.06 µg/mL). Through untargeted metabolomic analyses (UPLC-ESI(±)-QTOF-MS/MS) and subsequent stepwise computational metabolomics analyses, we identified the extract as primarily containing simple phenolics (e.g., gallic acid, ellagic acid, shikimic acid, and chlorogenic acid), flavonoid derivatives (e.g., quercetin, taxifolin, myricitrin, and afzelin), and other bioactive components, including dicarboxylic acids and germacrone. …”
Get full text

Seasonal distribution and cercarial shedding of Bulinus spp. snails: Implications for urogenital schistosomiasis control in the Simiyu Region, northwestern Tanzania by Nyanda C. Justine, Humphrey D. Mazigo, Antje Fuss, Bonnie L. Webster, Eveline T. Konje, Klaus Brehm, Andreas Mueller

“…Snails were collected using a standard scoop- and handpicking technique by two people for 15 min at each site. …”
Get full text