The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study by Bernhard Winder, Bernhard Winder, Bernhard Winder, Sophia J. Kiechl, Sophia J. Kiechl, Benoît Bernar, Benoît Bernar, Nina Gande, Anna Staudt, Anna K. Stock, Anna K. Stock, Christoph Hochmayr, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Stefan Kiechl, Ursula Kiechl-Kohlendorfer, Michael Knoflach, Michael Knoflach, the Early Vascular Ageing (EVA)-Tyrol Study Group, Carmen Reiter, Christina Schreiner Julia Klingenschmid, Julia Marxer, Martina Kothmayer, Maximilian Pircher, Manuela Bock-Bartl, Mandy Asare, Maximilian Bohl, Raimund Pechlaner

“…PA was rated by an in-person interview on the basis of average minutes of moderate- or vigorous sports per day and by the Baecke questionnaire expressed as Baecke score (BS).ResultsComplete data set was available for 1,001 adolescents with a mean age of 17.8 years (standard deviation ±0.9 years). 558 (55.7%) of participants were female. cIMT was positively associated with both measures of PA in univariate (minutes sports per day: p < 0.001; BS: p < 0.001) as well as multivariable analysis adjusting for established cardiovascular risk factors (minutes sports per day: p = 0.001; BS: p = 0.002). …”
Get full text

Wealth-based inequalities in tuberculosis prevalence among households having children and young adults in India: insights from Indian demographic and health surveys (2015–2021) by Saurabh Singh, Quazi Syed Zahiruddin, Sorabh Lakhanpal, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M Ravi Kumar, Yogesh Kumar Dhandh, Sarvesh Rustagi, Mohammed Alissa, Muhammad A. Halwani, Mohammed Garout, Hayam A Alrasheed, Maha F. Al-Subaie, Nawal A. Al Kaabi, Ali A. Rabaan, Sanjit Sah, Muhammed Shabil, Mahalaqua Nazli Khatib, Prakasini Satapathy

“…This research emphasizes the importance of comprehensive approaches to combat pediatric TB, combining clinical care with enhancements in living standards and access to basic amenities.…”
Get full text

Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation by Théotime Roussel, Cédric Hubas, Sébastien Halary, Mathias Chynel, Charlotte Duval, Jean-Paul Cadoret, Tarik Meziane, Léa Vernès, Claude Yéprémian, Cécile Bernard, Benjamin Marie

“…., 2023), we develop a specific analysis of the metabolomic diversity of 93 strains of Limnospira, grown under standardized lab culture conditions. Overall, this original work showed distinct chemical fingerprints that were correlated with the respective biogeographic origins of the strains. …”
Get full text

Prognostic factors for transplant-free survival in patients with secondary sclerosing cholangitis associated with critical illness by Christoph Schramm, Hartmut Schmidt, Christian Gerges, Alisan Kahraman, Christian M Lange, Jassin Rashidi-Alavijeh, Katharina Willuweit, Georgios Konstantis, Dorsa Ghaffar Loy Moghadam, Alexandra Frey, Nargiz Nuruzade, Moritz Passenberg

“…The C-index was 0.78 (95% CI 0.65, 0.91), surpassing the model of end-stage liver disease score’s prognostic accuracy (Concordance Index at 3 years: 66.2% vs 74.9%).Conclusion These findings provide valuable insights for establishing standard exception criteria for this rare liver disease, which could lead to improved organ allocation. …”
Get full text

Associations of blood-based biomarkers of neurodegenerative diseases with mortality, cardio- and cerebrovascular events in persons with chronic coronary syndrome by Valerie Lohner, Laura Perna, Ben Schöttker, Robert Perneczky, Hermann Brenner, Ute Mons

“…Results: Participants with higher NfL levels had increased rates of all-cause and cardiovascular mortality (Hazard ratio per increase by one standard deviation (95 % confidence interval): all-cause mortality: 1.36 (1.10–1.68); cardiovascular mortality: 1.42 (1.05–1.93)). …”
Get full text

Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…Additionally, telephone assessment at week 4 includes the simplified mRS and PROMIS-10.Safety will be evaluated by standard assessments and occurrence of adverse events over the duration of the study.Discussion Interventions that enhance recovery beyond the acute period of stroke are needed. …”
Get full text

Association of vitamin D deficiency and insufficiency with uncontrolled type 1 diabetes Mellitus among Saudi pediatric patients; a hospital-based retrospective study by Salman Almansour, Abdullrahman Alsalamah, Mohammad Almutlaq, Ahmed Sheikh, Hamdan Z. Hamdan, Abdullah Al-Nafeesah, Ashwaq AlEed, Ishag Adam, Osama Al-Wutayd

“…Their 25(OH)D levels and thyroid function were measured using standard methods.ResultsOf the 218 children in this study, 182 (83.5%) had uncontrolled T1DM, while only 36 (16.5%) had controlled T1DM. …”
Get full text

Laryngeal recurrence sites in patients previously treated with transoral laser microsurgery for squamous cell carcinoma by P. Horwich, M. H. Rigby, C. MacKay, J. Melong, B. Williams, M. Bullock, R. Hart, J. Trites, S. M. Taylor

“…The Kaplan-Meier estimate for overall survival at 36 months was 40% post TL with a standard error (SE) of 13.6%. DSS was 47% (SE 14.2%), and locoregional control was 55% (SE 14.5%) post TL. …”
Get full text

Association between occupational exposure to gasoline and anemia: a retrospective cohort study in China by Lan Lin, Hongmei Cao, Beining Wu, Jin Wang, Lin Song, Weiling Chan, Geyang Li, Li Zhou, Jing Xiao, Lejia Zhu, Yulong Lian

“…Occupational exposure concentration of gasoline was measured based on the Chinese national standard (GBZ-T300.62-2017). Logistic regression was conducted to analyze the associations of occupational exposure to gasoline and anemia. …”
Get full text

Bulk and single-cell transcriptome revealed the metabolic heterogeneity in human glioma by Yong Xiao, Mengjie Zhao, Ran Wang, Liang Liu, Chong Xiang, Taiping Li, Chunfa Qian, Hong Xiao, Hongyi Liu, Yuanjie Zou, Xianglong Tang, Kun Yang

“…Cell-cell communication analysis was performed at single-cell resolution using the R package CellChat and at spatial resolution using the standard stLearn pipeline. Results: Glioma samples were stratified into two prognostic subtypes. …”
Get full text

The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach by Irena Markova, Denisa Miklankova, Martina Hüttl, Petr Kacer, Jelena Skibova, Jan Kucera, Radislav Sedlacek, Tereza Kacerova, Ludmila Kazdova, Hana Malinska

“…Male Wistar control rats and HHTg rats were fed a standard diet and observed over the course of ageing at 3, 12, and 20 months of age. …”
Get full text

Fetal Hemoglobin as a Predictive Biomarker for Retinopathy of Prematurity: A Prospective Multicenter Cohort Study in Portugal by Mariza Fevereiro-Martins, Laura Aguiar, Ângela Inácio, Carlos Cardoso, Ana Carolina Santos, Carlos Marques-Neves, Hercília Guimarães, Rui Pinto, Manuel Bicho

“…Clinical data were collected during hospitalization, and HbF fractions were measured from blood samples in the first four weeks of life using standardized methods. Infants were stratified by ROP presence and treatment requirement. …”
Get full text

Effect of Fish Meal Substitution with Black Soldier Fly (Hermetia illucens) on Growth Performance, Feed Stability, Blood Biochemistry, and Liver and Gut Morphology of Siamese Fight... by Zulhisyam Abdul Kari, Guillermo Téllez-Isaías, Noor Khalidah Abdul Hamid, Nor Dini Rusli, Khairiyah Mat, Suniza Anis Mohamad Sukri, Muhammad Anamul Kabir, Ahmad Razali Ishak, Nazri Che Dom, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Martina Irwan Khoo, Faizuan Abdullah, Md Shahjahan, Md Fazle Rohani, Simon J. Davies, Lee Seong Wei

“…After 60 days, the fish fed with 13% BSFL had the highest final length, final weight, net weight gain, specific growth rate, weight gain, and gastrointestinal weight, with mean and standard deviation values of 3.97±0.43 cm, 3.95±0.1 g, 2.78±0.1 g, 4.63±0.17, 4.65±0.13, 237.26±7.9%, and 0.04±0.01 mg, respectively. …”
Get full text

Evaluation of naturally occurring IgG anti-Vi antibody titers as predictors and correlates of typhoid fever in Dhaka, Bangladesh by Farhana Khanam, Natasha Y. Rickett, Faisal Ahmmed, Md Taufiqul Islam, Cecilia Kathure Mbae, Justin Im, Asma Binte Aziz, Beatrice Ongadi, Fahima Chowdhury, Ashraful Islam Khan, Afroza Akter, Md Golam Firoj, Sadia Isfat Ara Rahman, Kassa Haile, Se Eun Park, Martin Bundi Mwebia, Moses Mwangi, Benjamin Ngugi, Meseret Gebre Behute, Kelvin Kering, Suneth Agampodi, Suman Kanungo, Xinxue Liu, Andrew J. Pollard, K. Zaman, Deok Ryun Kim, Samuel Kariuki, Firdausi Qadri, John D. Clemens

“…Plasma IgG anti-Vi antibodies were measured using a standard enzyme-linked immunosorbent assay in random serosurveys of a population that had not previously received typhoid vaccination. …”
Get full text

Development and effectiveness evaluation of an interactive e-learning environment to enhance digital health literacy in cancer patients: study protocol for a randomized controlled... by Lukas Lange-Drenth, Hellena Willemer, Mirjam Banse, Anke Ernst, Anne Daubmann, Anja Holz, Christiane Bleich, Susanne Weg-Remers, Holger Schulz

“…Additionally, patients’ often limited ability to find and evaluate cancer-related online information can lead to misinformation.ObjectiveAn interactive e-learning environment to promote digital health literacy will be developed and evaluated for effectiveness.Primary hypothesisCancer patients who use the e-learning environment (IG1.1–IG1.3) or the content of the environment as a non-interactive PDF file (IG2) will show greater improvement in their digital health literacy from baseline to 8 weeks after baseline compared to patients who receive no such intervention, but are referred to a standard information brochure.MethodsThe hypothesis will be tested in a stratified randomized controlled superiority trial with five parallel groups and the primary endpoint of digital health literacy. …”
Get full text

Transcatheter Closure of Perimembranous and Intracristal Ventricular Septal Defects Using Amplatzer Duct Occluder II in Children by Shenrong Liu, Wenqian Zhang, Junjie Li, Shushui Wang, Mingyang Qian, Jijun Shi, Yumei Xie, Zhiwei Zhang

“…We retrospectively analyzed all children, who presented to our hospital consecutively between March 2014 and June 2020 for attempted transcatheter closure of pmVSD or icVSD with the ADO II device. Standard safety and last-follow-up outcomes were assessed and compared. …”
Get full text

Radiation knowledge and anxiety levels among residents proximity to the world’s first AP1000 nuclear power unit by Jiadi Guo, Zhiqiang Xuan, Cuiping Lei, Taotao Zheng, Zhongjun Lai, Xiaoji Hao, Shunfei Yu, Yiyao Cao

“…Respondents were surveyed face-to-face by investigators who received standardized training. The results of the survey were collated and analysed to assess the RRK and NERK levels of the respondents from both subjective and objective perspectives, and the anxiety levels were assessed using the Likert Scale. …”
Get full text

Stature estimation and sex determination from contemporary Northeastern Thai clavicles using discriminant function and linear regression analyses by Chanasorn Poodendaen, Poonikha Namwongsakool, Sitthichai Iamsaard, Nareelak Tangsrisakda, Rarinthron Samrid, Chadaporn Chaimontri, Worrawit Boonthai, Suthat Duangchit

“…Materials and method: Four hundred dry clavicles (200 males, 200 females) identified for sex and height before body donation were measured for six standardized parameters including maximum length of clavicle (MaxL), anterior-posterior width at the acromion end surface (APA), anterior-posterior width at the sternal end surface (APS), superior-inferior width at the acromion end surface (SIA), superior-inferior width at the sternal end surface (SIS), and circumference at the mid-shaft of clavicle (CirMid), respectively. …”
Get full text

Disease burden of biliary tract cancer in 204 countries and territories, 1990–2021: A comprehensive demographic analysis of the Global Burden of Disease Study 2021 by Xuheng Sun, Jiangmei Liu, Wei Zhang, Yijun Wang, Yan Jiang, Lijun Wang, Yixin Zou, Yuxuan Xiao, Yongbing Xiang, Maolan Li, Maigeng Zhou, Yingbin Liu, Sihan Zhou, Xiuyuan Hao

“…However, the average global age-standardized rates (ASRs) of incident cases, deaths, and DALYs shrunk by −11.46% (95% UI: −21.91 to 3.35%), −24.09% (95% UI: −33.19 to 16.88%), and −26.25% (95% UI: −35.53 to 18.36%), respectively, from 1990 to 2021. …”
Get full text

A Regional Gravimetric and Hybrid Geoid Model in Northern Greece from Dedicated Gravity Campaigns by Georgios S. Vergos, Dimitrios A. Natsiopoulos, Elisavet G. Mamagiannou, Eleni A. Tzanou, Anastasia I. Triantafyllou, Ilias N. Tziavos, Dimitrios Ramnalis, Vassilios Polychronos

“…., after the stochastic treatment of the adjusted residuals, gave a std of the difference to the GNSS/leveling data of 1.1 cm, with 99.8% and 99.9% of the height difference being smaller than the 1 cm and 2 cm standard errors, thus achieving a 1 cm accuracy regional geoid.…”
Get full text