Synthesis and characteristics of Fe/Ni/Cr oxide nanoparticles/PLA hybrid composite coatings on Mg–Zn–Ca alloy by Prakash Kumar, Aditya Kudva S, AnilKumar T, Ramesh S, M.R. Ramesh, Ashwini Prabhu, Gajanan Anne

“…The corrosion characteristics of developed samples were measured by electrochemical corrosion in standard simulation body fluid (SBF) at 37 °C. Furthermore, cytocompatibility of the PLA hybrid composites on osteoblast cells and apoptosis detection using acridine orange-ethidium bromide. …”
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Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination by Yue Zhang, Xia Lei, Hongdan Xu, Guoliang Liu, Yeqiu Wang, Huifeng Sun, Fang Geng, Ning Zhang

“…A rapid and validated UPLC-MS/MS method for simultaneous determination of the seven analytes including neoeriocitrin, luteolin-7-O-β-D-glucoside, astragalin, naringin, eriodictyol, naringenin, and kaempferol in rats’ various tissues (heart, liver, spleen, lung, kidney, stomach, brain, uterus, ovary, and small intestine) using quercetin as the internal standard (IS) was developed after oral administration of TFDR to rats. …”
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First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies by Peter Ellmark, Jeffrey Yachnin, Ana Carneiro, Lena Schultz, Amanda Hahn, Sumeet Ambarkhane, Karin Enell Smith, Gustav J. Ullenhag

“…ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.Methods In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to patients with advanced, unresectable solid tumors having received multiple standard-of-care treatments. The study used single patient cohorts for rapid dose escalation up to 40 mg; thereafter a modified 3+3 design up to 900 mg. …”
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Prospective study of the association between chronotype and cardiometabolic risk among Chinese young adults by Tingting Li, Yang Xie, Shuman Tao, Liwei Zou, Yajuan Yang, Fangbiao Tao, Xiaoyan Wu

“…The cardiometabolic (CM)-risk score was the sum of standardized Z scores based on gender for the 5 indicators: waist circumference (WC), mean arterial pressure (MAP), triglyceride (TG), homeostasis model assessment for insulin resistance (HOMA-IR), and high-density lipoprotein cholesterol (HDL-C), where the HDL-C is multiplied by-1. …”
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Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy by D. A. Rozenko, A. I. Shikhlyarova, L. N. Vaschenko, N. N. Popova, Yu. Yu. Arapova, A. Yu. Ardzha, A. A. Korobov

“…For the final assessment of the physiological and psychological state of the patients, a standardized questionnaires of the quality of life – ESAS, MOS-SF‑36, were used. …”
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From Pioneering Discoveries to Innovative Therapies: A Journey Through the History and Advancements of Nanoparticles in Breast Cancer Treatment by Basingab FS, Alshahrani OA, Alansari IH, Almarghalani NA, Alshelali NH, Alsaiary AH, Alharbi N, Zaher KA

“…The technical challenges include efficient and targeted delivery to tumor sites without affecting healthy tissue; biological, such as potential toxicity, immune system activation, or resistance mechanisms; economic, involving high production and scaling costs; and regulatory, requiring rigorous testing for safety, efficacy, and long-term effects to meet stringent approval standards. Finally, we have explored emerging trends, the potential for personalized medicine, and the ethical and social implications of this transformative technology. …”
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Typical Forms of Plans for Certain Investigative (Search) Actions by O. O. Khan

“…Taking into account the individual features of investigative (search) actions of certain types, the author has offered standard forms of interrogation plans, simultaneous interrogation of two or more already interrogated persons (face-to-face interrogation) and search in case of its conduct in the presence of the searched person. …”
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Improving timing resolution of BGO for TOF-PET: a comparative analysis with and without deep learning by Francis Loignon-Houle, Nicolaus Kratochwil, Maxime Toussaint, Carsten Lowis, Gerard Ariño-Estrada, Antonio J. Gonzalez, Etiennette Auffray, Roger Lecomte

“…For $${2 \times 2 \times 3}\,\hbox {mm}^{3}$$ 2 × 2 × 3 mm 3 crystals, implementing TWC results in a CTR of 129 ± 2 ps FWHM, while employing the CNN yields 115 ± 2 ps FWHM, marking improvements of 18 % and 26 %, respectively, relative to the standard LED estimator. For $${2 \times 2 \times 20}\,\hbox {mm}^{3}$$ 2 × 2 × 20 mm 3 crystals, both methods yield similar CTR (around 240 ps FWHM), offering a $$\sim$$ ∼ 15 % gain over LED. …”
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Neuroimaging predictors of malignant brain oedema after thrombectomy in ischemic stroke: a systematic review and meta-analysis by Linrui Huang, Xindi Song, Jingjing Li, Yanan Wang, Xing Hua, Meng Liu, Ming Liu, Simiao Wu

“…We estimated effect size for the association between predictors and MBE by odds ratios (ORs) or standardized mean differences (SMDs), and pooled results using random-effects modelling.Results We included 19 studies (n = 6007) with 17 neuroimaging factors and 5 models. …”
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Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications by Nick Boyne, Alison Duke, Jack Rea, Adam Khan, Alec Young, Jared Van Vleet, Matt Vassar

“…Inconsistent reporting poses risks to clinical decision-making and patient safety. Adopting standardized reporting guidelines, such as CONSORT Harms, and ensuring transparent updates in publications could enhance the accuracy and trustworthiness of safety data. …”
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Social Media Potential and Impact on Changing Behaviors and Actions in Skin Health Promotion: Systematic Review by Justyna Martyna Brzozowska, Joanna Gotlib

“…In health sciences, a standardized tool is needed to assess the quality of social media digital interventions. …”
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An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine by Alex Elswick, Amanda Fallin-Bennett, Karen L. Roper, Evan Batty, Christopher J. McLouth, William Stoops, Hilary L. Surratt, Carrie B. Oser

“…Abstract Background In the United States, complete abstinence persists as the standard for demonstrating recovery success from substance use disorders (SUDs), apart from alcohol use disorder (AUD). …”
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Trends in initial pharmacological COPD treatment in primary care (2010–2021): a population-based study using the PHARMO Data Network by Guilherme Rodrigues, Joana Antão, Qichen Deng, Brenda N. Baak, Alda Marques, Frits M. E. Franssen, Martijn A. Spruit

“…The annual proportions of individuals receiving a specific treatment among those diagnosed were calculated and directly standardized by age and sex according to the 2021 Dutch population structure. …”
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DADmax/NADmax Ratio: Criterion for the Production and Selection of Demolition Aggregates with Low-Water Absorption by Kamel Akroum, Bouzidi Mezghiche

“…Seven ordinary concretes served as parent concretes (PCs), and after 28 days of maturation, the PC specimens were divided with a metal mass and then separated into ten different subfractions using standardized sieves. Three representative samples per subfraction were subjected to a twenty-minute water absorption evaluation, resulting in seventy arithmetic averages over 210 trials. …”
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Global Insights into Cultured Meat: Uncovering Production Processes, Potential Hazards, Regulatory Frameworks, and Key Challenges—A Scoping Review by Renata Puppin Zandonadi, Maíra Catharina Ramos, Flavia Tavares Silva Elias, Nathalia Sernizon Guimarães

“…Cultured meat production presents some potential hazards (chemical, biological, and physical) that require food safety considerations: (i) genetic stability of cells/cell lines; (ii) microbiological hazards related to cell lines; (iii) exposure to substances used in the production process; (iv) toxicity and allergenicity of the product or its component for the population; (v) post-harvest microbiological contamination; (vi) chemical contamination/residue levels; and (vii) nutritional aspects/risks. Currently, no standardized testing approach exists for cultured meat. …”
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Effectiveness and cost-effectiveness of a web-based routine assessment with integrated recommendations for action for depression and anxiety (RehaCAT+): protocol for a cluster rand... by Reinhold Kilian, Harald Baumeister, Yannik Terhorst, Johannes Knauer, Paula Philippi, Selina Kallinger, Sandro Eiler, Tamara Waldmann, Morten Moshagen, Martina Bader

“…This study aims to evaluate the effectiveness and cost-effectiveness of such a platform for depression and anxiety (RehaCAT+) compared with the standard diagnostic system (RehaCAT) in cardiological and orthopaedic health clinics in routine care.Methods and analysis A two-arm, pragmatic, cluster-randomised controlled trial will be conducted. …”
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Lateral Decubitus 360° Capsular Release for Treatment of Recalcitrant End-Stage Adhesive Capsulitis by Juan Bernardo Villarreal-Espinosa MD, Rodrigo Saad Berreta BA, Richard Danilkowicz MD, Udit Dave BS, Melissa Carpenter BS, Jorge Chahla MD, PhD, Nikhil N. Verma MD

“…The shoulder’s bony landmarks are identified for proper placement of the arthroscopic portals. A standard posterior portal is first established followed by an anterior portal in the rotator interval. …”
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Improvement of a MALDI-TOF database for the reliable identification of Candidozyma auris (formally Candida auris) and related species by Hui-Hui Zhu, Miao-Miao Liu, Teun Boekhout, Qi-Ming Wang

“…This method will play a crucial role in accurately diagnosing infectious agents of the genus Candidozyma in clinical practice.IMPORTANCEImportance Candidozyma auris, also known as Candida auris, has quickly spread across the world, and prompt identification of C. auris from infected individuals is critical. However, a standard identification method is lacking for the identification of C. auris in clinical and public health laboratories. …”
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UKRAINIAN ENTREPRENEURSHIP IN POLAND: CHALLENGES AND OPPORTUNITIES by Valentyna Smachylo, Olha Rudachenko, Oleh Kulinich, Dmytro Simonov

“…As a result of the expert interview, a problem area was formed for Ukrainian business projects entering the Polish market: • lack of business analytics for successfully starting and running a business; • misunderstanding of internal market processes of the Polish market; • problems with financing; • lack of understanding of the legislation of Polish and European standards in general, peculiarities of taxation and accounting; • low efficiency and quality of conducting business processes; • mistrust of Ukrainian brands, the need to build a brand on the Polish market from “0”; • recruitment and work with personnel; • language problems. …”
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Predictive value of lymphocyte-associated inflammation index in post-stroke cognitive impairment: a systematic review and meta-analysis by Feng-le Mao, Xia He, Xia-lian Huang, Yue-ming Cheng, Fu-li Qin, Yan-qiu Wang

“…Combined effect sizes were calculated using weighted mean difference (WMD) or standardized mean difference (SMD) with 95% confidence intervals (CIs). …”
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