Phytochemical and toxicological evaluation of aqueous leaf extract of Premna integrifolia L. in male balb/c mice by Suman, Pratibha Gaurav, Rajesh Saini, Kavindra Nath Tiwari, Gautam Geeta Jiwatram

“…Safety evaluation of these herbal medications is necessary, so acute and sub-acute toxicity of plant leaf extract Premna integrifolia has been performed to standardize its dose regarding its therapeutic application in male fertility. …”
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Effectiveness of a personal health coaching intervention (diabetescoach) in patients with type 2 diabetes: protocol for an open-label, pragmatic randomised controlled trial by Oliver Faude, Fiona Streckmann, Lukas Zahner, Markus Gerber, Vivien Hohberg, Jan-Niklas Kreppke, Jan Kohl, Eleonora Seelig, Daniel König

“…All enrolled patients (n=90) will receive the standard medical treatment for T2D. The intervention group will receive personal health coaching by telephone and access to a smartphone and web application for 1 year. …”
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Copper Super-Dosing Improves Performance of Heat-Stressed Broiler Chickens through Modulation of Expression of Proinflammatory Cytokine Genes by Sudipto Haldar, Amrita Kumar Dhara, Sayantani Sihi Arora, Arpana Verma Mukherjee, Arup Nayak

“…Copper (Cu), an active component of a number of antioxidative defence components, should arrest these changes to take place although that may not be possible under the standard dosing regimen followed by the industry. To ascertain the optimum dose response that may be beneficial in sustaining the performance of chickens under heat stress (HS), broiler chickens (n = 400) were exposed to high ambient temperature (between 27.2°C and 35.3°C) during 1–35 d. …”
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Cyto-histological correlation of salivary gland lesions according to the Milan reporting system by Shireen Hamid, Muhammad Mudassar, Nida Hamid, Muhammad Sarwar Zia, Tariq Mehmood, Sadia Hameed

“… Objective: The objective of this study is to correlate FNAC outcomes according to the Milan Salivary Gland Cytology Reporting System (MSRSGC)system with histopathological findings of salivary gland lesions, taking as the gold standard. Study Design: Descriptive Retrospective study. …”
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Improving the Biostability of Extra Virgin Olive Oil with Olive Fruit Extract During Prolonged Deep Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…The PV did not exceed the standard limit in HTyr-EVOO at 210 °C/24 h; however, in non-supplemented EVOOs, it remained within the limits only up to 210 °C/18 h. …”
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Anterior Knee Pain Evaluation Following Anterior Cruciate Ligament (ACL) Reconstruction Using Anterior Half of The Peroneus Longus (AHPL) Autograft by Pontoh LAP, Dilogo IH, Kamal AF, Rhatomy S, Putra A, Fiolin J, Herdiman JA, Pontoh EW

“…ACL reconstruction is a standard treatment option, with various autograft sources available. …”
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Virtual online consultations: advantages and limitations (VOCAL) study by Trisha Greenhalgh, Joe Wherton, Sara Shaw, Charles Gutteridge, Emma Byrne, Isabel Hodkinson, Shanti Vijayaraghavan, Desirée Campbell-Richards, Satya Bhattacharya, Philippa Hanson, Seendy Ramoutar, Anna Collard, Joanne Morris

“…Data will be analysed and synthesised using a sociotechnical framework developed from structuration theory.Ethics approval City Road and Hampstead NHS Research Ethics Committee, 9 December 2014, reference 14/LO/1883.Planned outputs We plan outputs for 5 main audiences: (1) academics: research publications and conference presentations; (2) service providers: standard operating procedures, provisional operational guidance and key safety issues; (3) professional bodies and defence societies: summary of relevant findings to inform guidance to members; (4) policymakers: summary of key findings; (5) patients and carers: ‘what to expect in your virtual consultation’.Discussion The research literature on video consultations is sparse. …”
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Low-Temperature Preservation of Cherries by Batuch M. Guseynova, Ragima T. Musaeva

“…The nutritional profile was determined by standard methods of chemical analysis. The amount of juice lost during defrosting was assessed by the difference in weight before and after defrosting. …”
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Emissions and Chemical Components of PM2.5 from Simulated Cooking Conditions Using Traditional Cookstoves and Fuels under a Dilution Tunnel System by Colleen Marciel F. Rosales, Jinsang Jung, Mylene G. Cayetano

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Grisel’s Syndrome in Children: Two Case Reports and Systematic Review of the Literature by Nicole Pini, Martina Ceccoli, Patrizia Bergonzini, Lorenzo Iughetti

“…CT scan with 3D reconstruction is the gold standard for diagnosis, allowing the identification of the subluxation and the classification according to the Fielding–Hawkins grading system. …”
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Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial by Marina Reznik, MD, MS, Florinda Islamovic, MD, Jill S. Halterman, MD, MPH, Cheng-Shiun Leu, PhD, Jiaqing Zhang, PhD, Philip O. Ozuah, MD, PhD

“…Results: We included 107 children (53% male participants, 82% Hispanic, mean [standard deviation] age 9.0 [1.0] years, 76% with persistent or uncontrolled asthma). …”
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Participatory epidemiological approaches for risk assessment of bed bug (Insecta: Hemiptera: Cimicidae) infestation in public hospitals in the city of Faisalabad, Punjab, Pakistan by Arzoo Ashraf, Muhammad Sohail Sajid, Hafiz Muhammad Rizwan, Kashif Hussain, Muhammad Asif Mahmood, Muhammad Imran Arshad, Zain ul Abdin, Shumaila Ashraf, Malcolm K. Jones, Dalia Fouad, Farid S. Ataya

“…Bed bugs were collected and morphologically identified through a standard taxonomic key. A descriptive cross-sectional survey of patients using a pre-designed questionnaire containing open-ended and closed-ended questions was conducted for six months between January 2023 and June 2023. …”
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Effectiveness of cupping therapy for musculoskeletal pain: an umbrella review by Mohamed Magdy ElMeligie, Amr M. Yehia, Mahmoud Hamada Mohamed, Manna Mahmoud, Mohamed N. AlKholui, Ghada I. Mohamed

“…Conclusions Considering the standards, this umbrella review showed that most systematic reviews and meta-analyses using cupping therapy for musculoskeletal pain present low methodological quality. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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Novel transparent high-entropy sesquioxide ceramics with high physicochemical plasma etching resistance by Yu-Bin Shin, Su Been Ham, Ha-Neul Kim, Mi-Ju Kim, Jae-Woong Ko, Jae-Wook Lee, Young-Jo Park, Jung-Hyung Kim, Hyo-Chang Lee, Young Hwa Jung, Jung Woo Lee, Ho Jin Ma

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Verification of the Reliability of an Automated Urine Test Strip Colorimetric Program Using Colorimetric Analysis: Survey Study by Keigo Inagaki, Daisuke Tsuriya, Takuya Hashimoto, Katsumasa Nakamura

“…The agreement rate of the results of this program was investigated using the results of an automatic urine analyzer as the gold standard. ResultsCompared with the judgments of an automatic urine analyzer, the average agreement rate for 12 items (protein, glucose, urobilinogen, bilirubin, ketone bodies, specific gravity, occult blood, pH, white blood cells, nitrite, creatinine, and albumin) was 78.6%. …”
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Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease: a retrospective cohort study from the MIMIC-IV database by Yuwen Chen, Jian Xu, Fan He, An’an Huang, Jie Wang, Bingchen Liu, Qucheng Wei

“…Cox regression analysis revealed that SHR was independently associated with both in-hospital mortality (per standard deviation (SD) increase: hazard ratio (HR) 1.35, 95% confidence interval (CI) 1.23–1.48) and ICU mortality (per SD increase: HR 1.37, 95% CI 1.21–1.54). …”
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Corneal endothelial dysfunction: etiology, pathogenesis, and current treatment approaches by S.V. Trufanov, E.P. Salovarova

“…Previously, penetrating keratoplasty has been the gold standard surgical procedure for corneal endothelial failure. …”
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Targeted generative data augmentation for automatic metastases detection from free-text radiology reports by Maede Ashofteh Barabadi, Xiaodan Zhu, Wai Yip Chan, Amber L. Simpson, Richard K. G. Do

“…We also compare metastasis identification accuracy between models utilizing institutionally standardized reports vs. non-structured reports, which complicate the extraction of relevant information, and show how including patient history with a customized model architecture narrows the gap between those two setups from 7.3 to 4.5 points on F1-score under LoRA tuning. …”
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Attitudes of German General Practitioners Toward eHealth Apps for Dementia Risk Reduction: Qualitative Interview Study by Adrian Schultz, Melanie Luppa, Markus Bleckwenn, Steffi G Riedel-Heller, Andrea Zuelke

“…GPs stated that they only addressed dementia once abnormalities were already present or less frequently when a patient or relative expressed a direct wish, while individual dementia risk or standardized diagnostic during routine check-ups were mentioned much less frequently. …”
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