Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…Objective Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). …”
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Feasibility and accuracy of continuous intraabdominal pressure monitoring with a capsular device in human pilot trial by Chien-Hung Liao, David A. Spain, Chih-Chi Chen, Chi-Tung Cheng, Wei-Cheng Lin, Dong-Ru Ho, Heng-Fu Lin, Fausto Catena

“…In the summarized data, the mean IAPdot is 0.6 mmHg lower than the IAPivp, with a standard deviation of 1.68 mmHg. However, capsule measurements showed excellent correlation with intravesical IAP measurements, with an intraclass correlation coefficient of 0.916 (95% CI: 0.8821–0.9320). …”
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Radiographic Evaluation of The Bone Density Around Tooth-Anchored One-Piece Immediate-Loading Dental Implant by Bangen Mohammed Karam, Bahar Jaafar Selivany, Huda Jameel Qasim, Rafah Hussein Mohammed

“…Grayscale values and texture parameters, including mean, standard deviation (SD), and coefficient of variation (CV), were analyzed in regions of interest (ROIs) around the implants. …”
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Reliability, Objectivity, Validity and Reference Levels of the Austrian Balance Check (ABC)—A Novel Balance Field Test for Children, Adolescents and Young Adults to Assess Static B... by Gerald Jarnig, Reinhold Kerbl, Mireille N. M. van Poppel

“…Objectivity was excellent in both groups (RSC (ICC_2.1 = 0.99, 95% CI 0.98 to 0.99); ESC (ICC_2.1 = 0.98, 95% CI 0.96 to 0.99)). A gold standard comparison using an electronic force plate showed a strong negative correlation: participants with high overall ABC scores showed less movement on the force plate (parameters of the center of pressure: surface area (ρ = −0.61), mean velocity (ρ = −0.65) and path length (ρ = −0.65). …”
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Nurses retention: the impact of transformational leadership, career growth, work well-being, and work-life Balance by Eman Sameh AbdELhay, Samah Mohamed Taha, Mona Metwally El-Sayed, Sahar Hassan Helaly, Islam Sameh AbdELhay

“…Work-life balance was found to be a strong predictor, with an unstandardized coefficient (B) of 0.255 (p < 0.001) and a standardized coefficient (β) of 0.426, indicating a positive relationship with retention, transformational leadership also significantly influenced retention, with a B of 0.082 (p = 0.002) and a β of 0.171. …”
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Psychometric Validation of the German Version of the Rapid Assessment of Physical Activity (RAPA): A Secondary Analysis of Cross‐Sectional Survey Data by Hannah McGowan, Rik Crutzen, Tari Topolski, Stefan Tino Kulnik

“…These initial findings lend themselves to future dedicated psychometric validation studies of the German RAPA (against gold‐standard physical activity questionnaires or direct physical activity measures) to further explore the potential of this tool for use in German‐speaking geriatrics healthcare.…”
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Large language models for accurate disease detection in electronic health records: the examples of crystal arthropathies by Kim Lauper, Denis Mongin, Nils Bürgisser, Samia Mehouachi, Clement P. Buclin, Delphine S. Courvoisier, Etienne Chalot

“…All paragraphs were manually reviewed and classified by two healthcare professionals into disease (true gout) and non-disease (gold standard). The LLM’s accuracy was tested using few-shot and chain-of-thought prompting and compared with a regular expression (regex)-based method, focusing on the effects of model parameters and prompt structure. …”
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Influence of human settlements factors on the spatial distribution patterns of traditional villages in Liaoning province by Guiqiao Tao, Xueming Li, Shenzhen Tian, Hang Li, Yishan Song

“…At the municipal scale, the distribution is relatively uneven and primarily located in the cities of Chaoyang, Jinzhou, Huludao, Panjin, Anshan, and Dalian. (3) The majority of traditional villages are distributed along the southwest–northeast axis of the standard deviation ellipse, which corresponds with the main mountain ranges of Liaoning. (4) The distribution density features a western continuous clustering, central and eastern scattered clustering, and edge clustering pattern. (5) The spatial distribution patterns of traditional villages in Liaoning are influenced by various human settlements factors, with spatial variation in the nature and intensity of the effects of these factors. (6) The natural factors of human settlements are the dominant factors in the spatial distribution patterns of traditional villages, while the humanistic factors of human settlements have a dual impact on these patterns. …”
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BMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals by Hirokazu Taniguchi, Miho Ueda, Yukiko Kobayashi, Takatomo Shima

“…Multivariable-adjusted logistic regression analyses using the rate of change per year with standardized values found that BMI gain was strongly associated with the onset of MASLD for both men (OR: 1.90, 95% CI: 1.64–2.19) and women (OR: 1.95, 95% CI: 1.72–2.21). …”
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Responsiveness Index versus the RASS-Based Method for Adjusting Sedation in Critically Ill Patients by Johanna E. Wennervirta, Mika O. K. Särkelä, Markus M. Kaila, Ville Pettilä

“…Patients received propofol and oxycodone, if possible. The following standardized sedation protocol was utilized in both groups to achieve the predetermined target sedation level: either RI 40–80 (RI group) or RASS −3 to 0 (RASS group). …”
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The combined manifestations of dramatically sore throat, congested and edematous mucosa, no-swelling tonsil are specific in acute Omicron pharyngitis by Lei Zhou, Lineng Zhang, Feng Xu

“…When compared with the gold standard measurement of Sars-Cov-2 virus antigen or nucleic acid, the diagnostic panel has a sensitivity of 66.7% and a specificity of 91.7%. …”
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UK policymaker and expert perspectives on the smoke-free generation policy: a qualitative study by Rachael L Murray, Joanne Morling, Nathan Davies, Tessa Langley, Manpreet Bains

“…This study explores the context in which UK may be the first country to introduce SFG, identifies potential barriers and facilitators to SFG implementation and outlines possible approaches to SFG policy design.Methods We conducted 19 qualitative semistructured interviews with policymakers and health leaders in England, Scotland and Wales, including politicians, public health experts, academics, trading standards experts (responsible in UK for enforcing age restrictions on products), clinicians and civil society (charity sector) representatives. …”
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Predictive Factors of Concerns about Falling in People with Parkinson’s Disease: A 3-Year Longitudinal Study by Magnus Lindh-Rengifo, Stina B. Jonasson, Niklas Mattsson, Susann Ullén, Maria H. Nilsson

“…The strongest (according to the standardized regression coefficient, β) predictor of concerns about falling was walking difficulties (β = 0.378), followed by age (0.227), problems maintaining balance while dual tasking (0.172), and needing help in daily activities (0.171). …”
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Sonochemical Microstructuring of Sodium Alginate to Increase its Effectiveness in Bakery by Anastasia V. Paymulina, Irina Yu. Potoroko, Natalia V. Naumenko, Oleg K. Motovilov

“…The quality assessment of bakery products followed State Standard 58233-2018. The process of sonochemical microstructuring depolymerized large particles of sodium alginate into shorter ones: 5670 nm – 30.6%, 502 nm – 53.4%, 56.1 nm – 16%. …”
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Immunogenicity, Efficacy, and Effectiveness of Two-Dose and Shorter Schedules of Hepatitis E Vaccine: A Systematic Review by Bilal Azam, Melanie Marti, Amit Goel, Rakesh Aggarwal

“…In these studies, following administration of the HEV 239 vaccine in two doses at 0 and 1 month or a three-dose rapid (0, 7, and 21 days) schedule, anti-HEV antibody seroconversion rates were similar to and geometric mean concentrations of anti-HEV antibody were only slightly lower than those following the standard three-dose schedule. In individuals who were seropositive for anti-HEV antibodies at baseline, the antibody response persisted for several years irrespective of the number of vaccine doses, and in those who were seronegative at baseline, administration of two vaccine doses induced antibodies whose level remained substantially high till at least 13 months of follow-up. …”
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Association between ethylene oxide exposure and cognitive function in older adults from NHANES data by Meng Sun, Meng Cai, Sisi Sun, Huan Liu, Guo Chen

“…Weighted linear regression analysis, weighted logistic regression analysis, and restricted cubic spline models were employed to assess the association between HbEO and standardized z-scores of four cognitive tests. Firstly, analysis of variable characteristics across the different log10-transformed HbEO groups revealed that HbEO was higher in males, non-Hispanic whites, and smokers and that Z scores for Delayed Recall Test (DRT), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST) decreased as HbEO increased (p < 0.05). …”
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Continuous Patient-Independent Estimation of Respiratory Rate and Blood Pressure Using Robust Spectro-Temporal Features Derived From Photoplethysmogram Only by Muhammad Ahmad Sultan, Wala Saadeh

“…Similarly, BP approach has been validated on a large dataset derived from MIMIC-II (<inline-formula><tex-math notation="LaTeX">$\sim$</tex-math></inline-formula>1700 records) which has errors (mean absolute, standard deviation) of 5.0(6.3) and 3.0(4.0) for systolic and diastolic BP, respectively. …”
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Neovascular Glaucoma from Ocular Ischemic Syndrome Treated with Serial Monthly Intravitreal Bevacizumab and Panretinal Photocoagulation: A Case Report by Hassaan Asif, Zhuangjun Si, Steven Quan, Pathik Amin, David Dao, Lincoln Shaw, Dimitra Skondra, Mary Qiu

“…We term this treatment protocol the Salvaging Conventional Outflow Pathway in Neovascular Glaucoma (SCOPING) Protocol, and this is our (MQ and DS) standard of care for all NVG patients presenting with partially or completely open angles. …”
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Magnitude, risk factors and economic impacts of diabetic emergencies in developing countries: A systematic review. by Halefom Kahsay Haile, Teferi Gedif Fenta

“…The estimations of direct cost expenditure were standardized to 2023 USD.<h4>Result</h4>A comprehensive examination was conducted on the 40 eligible studies, with the majority originating from African sources. …”
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Investigation on inherent angle ventilation control of residential kitchen range hoods by Zhilin Guo, Huixing Li, Guohui Feng, Kailiang Huang, Tengfei Yu

“…When windows can be opened, setting a baffle on the range hood, the simulation results revealed that with a baffle angle of 120° and a length of 0.3 m, the particle concentration capture efficiency in the breathing zone increased by 34.59 %. This achieved the standard limit requirement of 50 µg/m3, thus meeting the indoor air quality requirements.…”
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