Rapid microcystin-LR detection using antibody-based electrochemical biosensors with a simplified calibration curve approach by Samuel Adjei-Nimoh, Lance-Nicolas Rances, Maha A. Tony, Hossam A. Nabwey, Woo Hyoung Lee

“…The simplified calibration curve was developed and used to predict unknown MC-LR concentrations in several lake water samples with a relative standard deviation (RSD) of 1.0–4.4% and a recovery of 75–112%, indicating the suitability of the developed biosensor and a streamlined calibration curve for rapid MC-LR measurements for different water bodies with similar water quality. …”
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Clinical, laboratory and histopathologica investigation of the protective effect of dimethylsulfoxide (dmso) on experimentally induced various types of intestinal strangulation obs... by Cengiz Ceylan, Yılmaz Koç

“…Moreover, intestinal mucosal damage was also determined based on Chiu's standard scale. One hour after reperfusion, statistically significant improvements were observed (P<0,05) on pH. …”
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Ultrastructure of Mauthner Cells in Fish Adapted to Long-Duration Vestibular Stimulation and the Effect of Ethanol by Nadezhda R. Tiras, Georgy V. Zherdev, Dmitry A. Moshkov

“…As training alone leads to the formation of additional desmosome-like contacts of standard length, it is possible that although a sufficient amount of such structures cannot be formed in the M-cells of ethanol-exposed trained fish, the existing contacts can be elongated. …”
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PoWBWM: Proof of work consensus cryptographic blockchain-based adaptive watermarking system for tamper detection applications by P. Aberna, L. Agilandeeswari

“…The algorithms built for standard images may affect the watermark visibility when it is applied to HDR images as this produces high perceptual variations in the image compared to the original. …”
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Insights From Diverse Perspectives on Social Media Messages to Inform Young Adults With Cancer About Clinical Trials: Focus Group Study by Melissa P Beauchemin, Desiree Walker, Allison Rosen, Maria Frazer, Meital Eisenberger, Rhea K Khurana, Edward Bentlyewski, Victoria Fedorko, Corey H Basch, Grace C Hillyer

“… Abstract BackgroundLow rates of adolescent and young adult (YA; aged 15-39 y) clinical trial enrollment (CTE), particularly among underserved groups, have resulted in a lack of standardized cancer treatments and follow-up guidelines for this group that may limit improvement in cancer treatments and survival outcomes for YAs. …”
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Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study by Jin Xiong, Lei Xia, Lei Xia, Lei Xia

“…IntroductionPatients with extensive-stage small cell lung cancer (ES-SCLC) have a poor Q6 prognosis and there is no standard protocol for maintenance treatment. Anlotinib as a third-line or beyond therapy for ES-SCLC was proved to be effective.MethodsWe retrospectively screened of patients with ES-SCLC who started receiving anlotinib as first-line or second-line therapy at the Second Affiliated Hospital of Chongqing Medical University from November 2018 to December 2022. 30 patients treated with anlotinib based combination therapy and subsequent maintenance therapy were included. …”
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Physiology‐based pharmacokinetic model with relative transcriptomics to evaluate tissue distribution and receptor occupancy of anifrolumab by Pradeep Sharma, David W. Boulton, Lynn N. Bertagnolli, Weifeng Tang

“…Results of phase IIb and phase III trials led to the approval of intravenous anifrolumab 300 mg every 4 weeks (Q4W) alongside standard therapy in patients with moderate‐to‐severe SLE. …”
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Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patien... by Rahul Soangra, Marybeth Grant-Beuttler, Harriet Chang, Raymond Y. Wang

“…Ambulatory CLN2 patients typically receive standard of care treatment through biweekly intracerebroventricular (ICV) enzyme replacement therapy (ERT) involving recombinant human tripeptidyl peptidase 1, known as cerliponase alfa (Brineura®, Biomarin Pharmaceuticals). …”
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Influence of Dry Beach on the Dynamic Stability of Ash Storage Field: A Numerical Analysis by Fangtao She, Chang Liu, Xiangang Zhou, Changjun Qi, Jiulong Ding

“…In this study, an in situ standard penetration test was carried out on a constructed ash storage site in Northwest China to evaluate the potential for liquefaction of alluvial fly ash within the site, and the results show that dynamic liquefaction can occur within a newly constructed three-stage subdam. …”
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Healthcare Resource Utilization and Cost Comparisons of High-Protein Enteral Nutrition Formulas Used in Critically Ill Patients by Matthew C. Bozeman, Laura L. Schott, Amarsinh M. Desai, Mary K. Miranowski, Dorothy L. Baumer, Cynthia C. Lowen, Zhun Cao, Krysmaru Araujo Torres

“…Options include immunonutrition formulas of various compositions and standard high-protein formulas (StdHP). Additional research is needed on the health economic value of immunonutrition in a broad cohort of severely ill hospitalized patients. …”
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Energy Efficiency of Using Hybrid Heating Points in Conditions of Integration of Electrical and Thermal Networks of Urban Neighborhoods. Part 1. Justification of the Feasibility of... by A. V. Sednin, M. I. Pozdnyakova

“…With regard to district heating systems of electrical and thermal networks of urban neighborhoods, the use of hybrid heating points is achieved, which, unlike standard solutions, are equipped with electric boilers, thermal accumulators and heat pumps. …”
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Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 5 (Fr... by EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Jen Banach, Bin Zhou, Maria Teresa daSilva Felício, Laura Martino, Winy Messens, Angela Botteon

“…Food business operators should set up and validate a tailored WMP to identify physico‐chemical parameters, as well as microbial indicators and their threshold levels as performance standards for maintaining the fit‐for‐purpose microbiological quality of the process water during post‐harvest handling and processing operations.…”
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Value of dual-energy CT quantitative parameters combined with clinical features in diagnosis of stages T2 and T3 colorectal cancer by FANG Ni, WEI Xin, CHEN Weijuan

“…According to the pathological T staging criteria of Chinese Colorectal Cancer Diagnosis and Treatment Standard （2020 Edition）， they were divided into T2 group （n=43） and T3 group （n=48）. …”
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Establishing consensus on nutrition competencies for medicine: a Delphi study by Sumantra Ray, Breanna Lepre, Kylie J Mansfield, Eleanor J Beck

“…There remains a need to establish an accepted benchmark on nutrition competencies for medicine, as without consensus standards there is little likelihood of uniform adoption.Objective This study aimed to establish consensus on nutrition competencies using a Delphi process to inform a framework for nutrition education in medicine.Methods A three-round modified online Delphi survey of experts in healthcare practice, education and training, and experts by experience (service users) was conducted to provide a comprehensive consensus on nutrition competencies for medical practice.Results Fifty-two experts (15.1% response rate) participated in Round 1, 42 completed Round 2 and 47 completed Round 3. …”
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The influence of childhood trauma on social media-induced secondary traumatic stress among college students: the chain mediating effect of self-compassion and resilience by Xiqin Liu, Ye Yao, Siyu Zhu, Qiyong Gong

“…The purpose of this study was to explore the complex relationship linking childhood trauma to social media-induced STS in a large sample of college students.Methods: A total of 1151 Chinese college students from Chengdu, Sichuan Province of China completed a web-based cross-sectional survey, which included standard assessments of childhood trauma, self-compassion, resilience and social media-induced STS, as well as sociodemographic questionnaires. …”
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Organization of the regional cancer service to improve the detection of malignant new formations during the COVID-19 pandemic by S. V. Golubev, V. Yu. Startsev, Yu. V. Samsonov

“…To increase the detection of malignant neoplasms, it’s necessary to provide examination rooms in the districts of the MagO; drawing up a "map of contamination of the territory"; assessment of the conditions of human production activity and population density; introduction of the standard of examination of patients with cancer; increasing the alertness and qualifications of primary outpatient medical personnel.…”
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Design and maintenance of medical oxygen concentrators in Sub-Saharan Africa: a systematic review by Nahimiya Husen Ibrahim, James Wallace, Davide Piaggio, Leandro Pecchia

“…It highlighted a pressing need for improved healthcare infrastructure investment, context-aware OC design and novel standards and regulatory frameworks to support frugal innovation.…”
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Unhealthy alcohol use and risk of coronary heart disease among young and middle-aged adults by Jamal S. Rana, Felicia W. Chi, Isaac Acquah, Stacy A. Sterling

“…Results: The cohort comprised 44 % women, mean age (standard deviation) of 43.5 years (±13.1). Weekly alcohol intake above limits was associated with higher prevalence of cardiovascular risk factors, and a 26 %, 19 % and 43 % higher risk on the overall, men- and women-specific risk of CHD after adjusting for these risk factors (hazard ratio [95 % confidence interval] = 1.26[1.13 -1.40], 1.19[1.04–1.35] and 1.43[1.20–1.71], respectively). …”
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Sexual Health Advocacy for Guys (SHAG): a randomized trial of the impact of a text-messaging program on HIV incidence and STI testing among a national sample of sexual minority cis... by M. L. Ybarra, D. J. Feaster, R. Garofalo, S. Bull

“…Mediation will be assessed based on a product of coefficients approach with bootstrapped standard errors. Discussion This is the first randomized controlled trial (RCT) with a national sample of cisgender sexual minority adolescent boys and young men 13-22 years of age exploring the efficacy of a text messaging-based intervention in increasing HIV and STI testing, and PReP and PEP use. …”
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Measuring Digital Health Literacy in Older Adults: Development and Validation Study by SungMin Kim, Choonghee Park, Sunghyeon Park, Dai-Jin Kim, Ye-Seul Bae, Jae-Heon Kang, Ji-Won Chun

“…The model fit indices indicated excellent structural validity (Tucker-Lewis Index=0.924, comparative fit index=0.916, root-mean-square error of approximation=0.088, standardized root-mean-square residual=0.044). High convergent validity (average variance extracted>0.5) and reliability (composite reliability>0.7) were observed within each factor. …”
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