Perceived urban environment elements associated with momentary and long-term well-being: An experience sampling method approach by Yu-Ru Chen, Atsushi Nakagomi, Masamichi Hanazato, Noriyuki Abe, Kazushige Ide, Katsunori Kondo

“…LWB was positively associated with MWB (standardized coefficient=0.24) and urban elements—cafés/restaurants/bars (0.11), cultural/sports/education facilities (0.04), and public spaces (0.11). …”
Get full text

Test-Retest Reliability of Two Computationally-Characterised Affective Bias Tasks by Alexandra C. Pike, Katrina H. T. Tan, Hoda Tromblee, Michelle Wing, Oliver J. Robinson

“…We analysed the reliability of both summary statistics and parameters from computational models using Pearson’s correlations and intra-class correlations. Standard summary statistic measures from these affective bias tasks had reliabilities ranging from 0.18 (poor) to 0.49 (moderate). …”
Get full text

Shared perceptions of flavored cigarette pack design among young adults who smoke in Mexico and the Philippines by Graziele Grilo⁺, Jennifer L. Brown⁺, Joanna E. Cohen, Katherine Clegg Smith

“…These findings also support the implementation of plain and standardized packaging and flavor bans that would also limit product innovation such as capsules.…”
Get full text

Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-... by Sami Jebali, Chaouki Belgacem, Mohamed Radhouen Louhaichi, Senda Bahri, Latifa Latrous El Atarche

“…The described method shows excellent linearity over a range of 30 to 70 μg·mL−1 for all compounds with correlation coefficients higher than 0.995. The standard deviations of the intraday and interday precision were between 0.75 and 1.94%. …”
Get full text

Quantitative analysis and pharmacokinetic study of a novel diarylurea EGFR inhibitor (ZCJ14) in rat plasma using a validated LC-MS/MS method by Zuo Sai-Jie, Cheng Xiao-Liang, Liu Dong-Zheng, Feng Wei-Yi, Cao Yong-Xiao, Zhang San-Qi

“…Chromatographic separation of ZCJ14 and internal standard (IS) [1-phenyl-3-(4-((3-(trifluoromethyl)phenyl)amino) quinazolin-6-yl)urea] was accomplished by gradient elution using the Kromasil C18 column. …”
Get full text

FreshWater Watch: Investigating the Health of Freshwater Ecosystems, from the Bottom Up by Isabel Bishop, Amedeo Boldrini, Wim Clymans, Charlotte Hall, Heather Moorhouse, Stephen Parkinson, Kesella Scott-Somme, Ian Thornhill, Steven Loiselle

“…Herein, we outline the criteria used to develop a citizen science monitoring program for water quality, based on a standardized methodology designed to support the Agenda 2030 indicator 6.3.2 and the EU’s Water Framework Directive. …”
Get full text

A co-registration method to validate in vivo optical coherence tomography in the breast surgical cavity by Rowan W. Sanderson, Renate Zilkens, Peijun Gong, Imogen Boman, Ken Y. Foo, Skandha Shanthakumar, James Stephenson, Wei Ling Ooi, José Cid Fernandez, Synn Lynn Chin, Lee Jackson, Mireille Hardie, Benjamin F. Dessauvagie, Anmol Rijhumal, Saud Hamza, Christobel M. Saunders, Brendan F. Kennedy

“…Breast-conserving surgery accompanied by adjuvant radiotherapy is the standard of care for patients with early-stage breast cancer. …”
Get full text

Assessment of cardio-oncology knowledge and practice among healthcare providers in Saudi Arabia: a comprehensive nationwide survey by Hisham A. Badreldin, Nada Alsuhebany, Lama Alfehaid, Mohammed Alzahrani, Maha Aldoughaim, Abdullah M. Alrajhi, Jumanah Alsufyani, Dania Elsherif, Kanan Alshammari

“…Despite agreement on the need for cardiotoxicity management, only one-third recommended cardioprotective agents as standard care. Conclusion There is a notable deficiency in formal training and resources for cardio-oncology in Saudi Arabia. …”
Get full text

Radial head arthroplasty vs. open reduction and internal fixation in Mason 3 radial head fractures: meta-analysis of prospective trials by Domenico De Mauro, MD, Sami Abou Chakra, Francesco Liuzza, MD, Amarildo Smakaj, MD, Giuseppe Rovere, MD, PhD, Giulio Maccauro, MD, Omar El Ezzo, MD

“…Conclusion: Our findings reveal that the Mason type 3 RHFs treated with open reduction and internal fixation, exhibits a higher risk of complications compared to those patients treated with RHA. Moreover, the standardized mean difference analysis suggests that the ORIF group demonstrates a lower mean Broberg and Morrey Elbow score in comparison to the RHA group, with a higher functional recovery in RHA group.…”
Get full text

Recommendations for developing, documenting, and distributing data products derived from NEON data by Jeff W. Atkins, Kelly S. Aho, Xuan Chen, Andrew J. Elmore, Rich Fiorella, Wenqi Luo, Danica Lombardozzi, Claire Lunch, Leah Manak, Luis X. dePablo, Allison N. Myers‐Pigg, Sydne Record, Tong Qiu, Samuel Reed, Benjamin Ruddell, Brandon Strange, Christa L. Torrens, Kelsey Yule, Andrew D. Richardson

“…These data products include both field and remote sensing data collected using standardized protocols and sampling schema, with centralized quality assurance and quality control (QA/QC) provided by NEON staff. …”
Get full text

Refined methodology for quantifying Pseudomonas aeruginosa virulence using Galleria mellonella by Christopher M. R. Axline, Travis J. Kochan, Sophie Nozick, Timothy Ward, Tania Afzal, Issay Niki, Sumitra D. Mitra, Ethan VanGosen, Julia Nelson, Aliki Valdes, David Hynes, William Cheng, Joanne Lee, Prarthana Prashanth, Timothy L. Turner, Nathan B. Pincus, Marc H. Scheetz, Kelly E. R. Bachta, Alan R. Hauser

“…For this reason, some groups have used time-to-death as a measure of P. aeruginosa virulence, but methodologies have not been standardized. We provide a detailed protocol for using the time at which 50% of larvae have died (LT50) at a particular inoculum as a measure of P. aeruginosa virulence. …”
Get full text

Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

“…During manuscript preparation, the Standards for Reporting Qualitative Research will be followed. …”
Get full text

Tailoring the electron redistribution of RuO2 by constructing a Ru-O-La asymmetric configuration for efficient acidic oxygen evolution by Cong-Hui Li, Cheng-Zong Yuan, Xiaolei Huang, Hongrui Zhao, Fuling Wu, Lei Xin, Xiaomeng Zhang, Shufeng Ye, Yunfa Chen

“…Specifically, the as-prepared optimal La0.1Ru0.9O2 shows a low overpotential of 188 ​mV at 10 ​mA ​cm−2, a high mass activity of 251 A gRu−1 at 1.6 ​V vs. reversible hydrogen electrode (RHE), and a long-lasting durability of 63 ​h, far superior to the 8 ​h achieved by standard RuO2. Experiments and density functional theory calculations jointly reveal that the Ru-O-La asymmetric configuration could trigger electron redistribution in RuO2. …”
Get full text

Efficacy of Trimebutine Maleate (Trimedat®) in the Treatment of Patients with Functional Dyspepsia: Results of the “TREND” Observational Study by S. S. Kardasheva, I. M. Kartavenko, N. B. Maksimova, E. Yu. Yurieva, I. R. Popova, Ch. S. Pavlov, V. T. Ivashkin

“…The treatment was performed using trimebutine (Trimedat®) in a standard dosage of 200 mg × 3 times a day for 28 days.Results. …”
Get full text

Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent by Korfmann, Kevin, Sellinger, Thibaut Paul Patrick, Freund, Fabian, Fumagalli, Matteo, Tellier, Aurélien

“…The reproductive mechanism of a species is a key driver of genome evolution. The standard Wright-Fisher model for the reproduction of individuals in a population assumes that each individual produces a number of offspring negligible compared to the total population size. …”
Get full text

Recovering Pulsar Periodicity from Time-of-arrival Data by Finding the Shortest Vector in a Lattice by Dotan Gazith, Aaron B. Pearlman, Barak Zackay

“…We discuss the assumptions of the standard lattice techniques and quantify their performance and limitations.…”
Get full text

Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

“…Nowadays, targeted therapies remain the gold standard for many patients, but still they suffer from many adverse effects, including unexpected toxicity and intrinsic acquired resistance mutations, which lead to relapse. …”
Get full text

CDPMF-DDA: contrastive deep probabilistic matrix factorization for drug-disease association prediction by Xianfang Tang, Yawen Hou, Yajie Meng, Zhaojing Wang, Changcheng Lu, Juan Lv, Xinrong Hu, Junlin Xu, Jialiang Yang

“…Extensive cross-validation experiments on three standard datasets show that CDPMF-DDA achieves an average AUC of 0.9475 and an AUPR of 0.5009, outperforming existing models. …”
Get full text

In Vivo Magic Angle Magnetic Resonance Imaging for Cell Tracking in Equine Low-Field MRI by Carolin Horstmeier, Annette B. Ahrberg, Dagmar Berner, Janina Burk, Claudia Gittel, Aline Hillmann, Julia Offhaus, Walter Brehm

“…Six horses with induced tendinopathy in their forelimb superficial digital flexor tendons were injected locally either with superparamagnetic iron oxide-labelled multipotent mesenchymal stromal cells or serum. MRI included standard and magic angle image series in T1- and T2∗-weighted sequences performed at regular intervals. …”
Get full text

Vial-coated thin film microextraction for perfluoroalkyl carboxylic acids (PFCAs) determination in water by GC–MS by J․Mabel Luna-Díaz, Luz O․ Leal-Quezada, Laura Ferrer, Edwin Palacio

“…Intra- and inter-assay relative standard deviations (% RSD) were 4.9–2.2 % and 4.8–2.3 %, respectively, with a linear working range of 10–1000 ng L⁻¹ for the TFME-coated device. …”
Get full text