Validation of In-field Calibration for Low-Cost Sensors Measuring Ambient Particulate Matter in Kolkata, India by Siddharth Nobell, Arnab Majumdar, Shovon Mukherjee, Sukumar Chakraborty, Sanjoy Chatterjee, Soumitra Bose, Anindita Dutta, Sandhya Sethuraman, Daniel M. Westervelt, Shairik Sengupta, Rakhi Basu, V. Faye McNeill

“…The LCS data after cross-calibration correctly identified days as being in or out of attainment with the 24h National Ambient Air Quality Standard of 60 µg m−3 91% of the time. The corrected data accurately identifies days with an India scale Air Quality Index of “poor” or worse 94% of the time. …”
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Progress and insights from worldwide deep coalbed methane exploration and development by Jiaqi ZHANG, Zengqin LIU, Baojian SHEN, Shihu ZHAO, Xinjun CHEN, Jincheng YE

“…Increasing exploration efforts for different types of deep CBM, strengthening theoretical and technological research, accelerating the construction of standard systems, and enhancing industry support policies will help foster high-quality exploration and efficient development of deep CBM in China.…”
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Comparative reducing and carbohydrate enzyme inhibitory activities of the root, leaf, and seed of Picralima nitida by Erwin Osiele Onyekachukwu, Aishat Mary Osagie, Sylvia Oghogho Omage, Kingsley Omage, Marshall Arebojie Azeke

“…Methods: The antioxidant reducing power of P. nitida as well as its ability to inhibit selected enzymes of carbohydrate hydrolysis were evaluated using standard experimental methods. Results: Methanol extract of P. nitida leaves exhibited the strongest reducing power (653.52 mgASC/g) followed by the seed extract (620.11 mgASC/g). …”
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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…The PretoxTM Corpus is a gold standard corpus of preclinical treatment-related findings annotated by toxicology experts. …”
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Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial by Liv Mathiesen, Jeanette Schultz Johansen, Kjerstin Havnes, Kjell H. Halvorsen, Stine Haustreis, Lillann Wilsgård Skaue, Elena Kamycheva, Kirsten K. Viktil, Anne Gerd Granås, Beate H. Garcia

“…This paper presents the study protocol to explore the effects of the intervention with regard to healthcare use, health-related quality of life (HRQoL) and medication appropriateness in elderly patients.Methods and analysis A total of 500 patients aged ≥70 years will be included and randomised to control (standard care) or intervention group (1:1). The intervention comprises five steps mainly performed by pharmacists: (1) medication reconciliation at admission, (2) medication review during hospital stay, (3) patient counselling about the use of medicines, (4) a comprehensible and patient-friendly medication list with explanations in discharge summary and (5) postdischarge phone calls to the primary care level. …”
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Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels by Junyuan Du, Junyuan Du, Zhiyi Wu, Zhiyi Wu, Chunyang Zhu, Chunyang Zhu, Heng Yang, Heng Yang, Feike Zhao, Feike Zhao, Binghu Fang, Binghu Fang

“…The metabolic differences in Salmonella enterica Typhimurium standard strain ATCC 14028 with or without the addition of cystine were analyzed via untargeted metabolomics. …”
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Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019 by Saeid Safiri, Jessica A. Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J. M. Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh, Gary S. Collins, Ali-Asghar Kolahi

“…For adults, EBW was defined as a body mass index (BMI) exceeding 25 kg/m2, while for children aged 1 to 19 years, EBW was determined according to the standards set by the International Obesity Taskforce. …”
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Accumulation conditions and target area evaluation of coalbed methane in eastern uplift of Junggar Basin by Qixiang YU, Mi TIAN, Yu LUO, Fan YANG, Yan'e CHEN, Feng WANG, Yuqiao GAO, Tao GUO

“…The combustible gas (CH4) content is low relative to the total gas content in coal rocks. ④ CBM enrichment and accumulation models include piedmont fault depression, deep depression, and open slope gas escape models. ⑤ Evaluation parameters and classification standards were established. The Wucaiwan, Wutongwozi, Jimusaer, and Jinan sags are favorable areas for CBM exploration. …”
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Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial by Fumio Otsuka, Michael Højby Rasmussen, Takaaki Endo, Claus Sværke, Shigeyuki Tahara, Gudmundur Johannsson

“…Insulin-like growth factor I standard deviation score values were used for dose titration.ResultsIn total, 36 Japanese individuals were included (18 and 18 in the somapacitan and daily GH group, respectively). 35 completed the main period (34 weeks). …”
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Assessment of Atmospheric PM2.5 and PCDD/Fs Collected by Different High-volume Ambient Air Sampling Systems by Shih Yu Pan, Hung Wei Chen, Shih Chieh Hsu, Charles C.-K. Chou, Yu Chi Lin, Yuan Wu Chen, Kai Hsien Chi

“…Abstract To evaluate the difference in hazardous air pollutants in PM2.5 between reference method (National Institute of Environmental Analysis; NIEA A205) and high-volume air sampler (European standard:EN14907 and Japan method), we set up a sampling station on the campus of National Yang-Ming Chiao Tung University, northern Taiwan, during 2014–2015. …”
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Contribution of Aerosol Species to the 2019 Smoke Episodes over the East Coast of Peninsular Malaysia by Nur Nazmi Liyana Mohd Napi, Maggie Chel Gee Ooi, Mohd Talib Latif, Liew Juneng, Mohd Shahrul Mohd Nadzir, Andy Chan, Li Li, Samsuri Abdullah

“…High ambient PM2.5 concentration in the year 2019 based on New Malaysia Ambient Air Quality Standard (NMAAQS) was identified as high pollution episodes, HP1 and HP2 on the east coast Peninsular Malaysia (ECPM). …”
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Virtual online consultations: advantages and limitations (VOCAL) study by Trisha Greenhalgh, Joe Wherton, Sara Shaw, Charles Gutteridge, Emma Byrne, Isabel Hodkinson, Shanti Vijayaraghavan, Desirée Campbell-Richards, Satya Bhattacharya, Philippa Hanson, Seendy Ramoutar, Anna Collard, Joanne Morris

“…Data will be analysed and synthesised using a sociotechnical framework developed from structuration theory.Ethics approval City Road and Hampstead NHS Research Ethics Committee, 9 December 2014, reference 14/LO/1883.Planned outputs We plan outputs for 5 main audiences: (1) academics: research publications and conference presentations; (2) service providers: standard operating procedures, provisional operational guidance and key safety issues; (3) professional bodies and defence societies: summary of relevant findings to inform guidance to members; (4) policymakers: summary of key findings; (5) patients and carers: ‘what to expect in your virtual consultation’.Discussion The research literature on video consultations is sparse. …”
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Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease: a retrospective cohort study from the MIMIC-IV database by Yuwen Chen, Jian Xu, Fan He, An’an Huang, Jie Wang, Bingchen Liu, Qucheng Wei

“…Cox regression analysis revealed that SHR was independently associated with both in-hospital mortality (per standard deviation (SD) increase: hazard ratio (HR) 1.35, 95% confidence interval (CI) 1.23–1.48) and ICU mortality (per SD increase: HR 1.37, 95% CI 1.21–1.54). …”
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Multiple use of preservative-free single dose unit dexamethasone 0.1% eye drops is safe within 24 hours by Marco Rossi, Michael A Thiel, Frank Bochmann, Philipp B Baenninger, Claude Kaufmann, Fabienne C Fierz, Silvan Locher, Lucas Bachmann, Irena Mitrovic, Jeremy P Howell

“…Contamination rate was assessed with a standard clinical culturing protocol without introducing a positive control.Results 110 eyes of 109 patients were evaluated. …”
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miR-182 promoter hypermethylation predicts the better outcome of AML patients treated with AZA + VEN in a real-world setting by Yilan Xu, Danyang Li, Na Wang, Bei Ge, Chen Meng, Min Zhao, Zihan Lin, Min Li, Yigang Yuan, Yue Cai, Liuzhi Shi, Shenmeng Gao, Haige Ye

“…Abstract Background 5-Azacytidine (AZA) combined with the BCL2 inhibitor Venetoclax (VEN) is the standard treatment for elderly acute myeloid leukemia (AML) patients or those who are unfit for intensive chemotherapy (elderly or unfit AML). …”
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Lithological and geochemical characterization of ‘adinole’ artefacts from cave deposits in southwest Wales: A material of choice during the late Middle to Upper Palaeolithic by Richard Bevins, Elizabeth A. Walker, Nick Pearce, Duncan Pirrie, Rob Ixer, Ian Saunders, Matthew Power

“…Twenty-three artefacts previously identified as being manufactured from adinole, a fine-grained metasomatic rock, from late Middle to Upper Palaeolithic cave sites in southwest Wales have been re-examined in terms of their petrology and geochemistry. Standard petrography has been combined with automated SEM-EDS analysis for a single artefact to determine the mineralogy and textures of that artefact, while portable XRF and μXRF have been combined to establish the geochemical characteristics of all twenty-three artefacts analysed. …”
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Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study by Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Luana Madalena Sousa, Luana Madalena Sousa, Luana Madalena Sousa, Patrícia Couceiro, Patrícia Couceiro, Patrícia Couceiro, Patrícia Couceiro, António Martinho, Joana Rodrigues, Ruben Fonseca, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Paulo Freitas-Tavares, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova

“…Soft tissue sarcomas (STS) encompass over 50 histologic subtypes, representing more than 1% of solid tumors. Standard treatments include surgical resection and therapies such as anthracyclines or trabectedin for advanced cases, though challenges persist due to the tumor microenvironment’s complexity and limited immune profiling data. …”
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In vitro Antibacterial Efficacy of Bidens pilosa, Ageratum conyzoides and Ocimum suave Extracts against HIV/AIDS Patients’ Oral Bacteria in South-Western Uganda by Joseph Obiezu, Chukwujekwu Ezeonwumelu, Muhammad, Ntale, Steve, Okwudili Ogbonnia, Ezera, Agwu, Julius, Kihdze Tanayen, Keneth Iceland, Kasozi, Okonkwo, Chukwudi Onyeka, Anthonia, Shodunke, Ambrose, Amamchukwu Akunne, Onokiojare, Ephraim Dafiewhare, Jennifer, Chibuogwu Ebosie, Frederick, Byarugaba

“…The susceptibility, MIC and MBC of each extract were determined using standard protocols. The bacteria had significant (p < 0.05) respective total susceptibilities of 35 [28.7%] to BPA; 42 [34.4%] to BPE; 61 [50.0%] to ACA; 45 [36.9%] to ACE; 38 [31.1%] to OSA; 32 [26.3%] to OSE; 105 (86.0%)] to ceftriaxone. …”
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Chronic Myeloid Leukemia: Part II—Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin

“…**Background:** Tyrosine kinase inhibitors (TKIs) are the standard-of-care treatment for chronic myeloid leukemia in chronic phase (CML-CP). …”
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Survival and risk factors for metastatic colorectal cancer patients with a history of prior malignancy by Yiwen Qiu, Nida Cao, Dan Meng, Jian Yuan, Yingjie Zhu

“…Therefore, we advocate for active standardized treatment for these patients and propose expanding the range of prior malignancies included in clinical trials based on publication timelines, primary tumour locations, and genetic testing results. …”
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