Investigation of Crinum solapurense leaves extract for antidiabetic activity and histopathological evaluation in an in-vivo experimental model by Sunayana Mali, Gaurav Jain, Jyotiram Sawale, Audumbar Mali

“…Results: After inducing diabetes in rats by using dexamethasone, various groups of rats were treated with distilled water, a standard antidiabetic drug used as a Glibenclamide (GLC), and lower, medium, and higher doses of C. solapurense leaf extracts like 100.00 mg/kg, 200.00 mg/kg & 400.00 mg/kg respectively. …”
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Presence of distinct operant phenotypes and transient withdrawal-induced escalation of operant ethanol intake in female rats by Joseph R Pitock, Shannon R Wheeler, Arleen Perez Ayala, Shikun Hou, Nathaly M Arce Soto, Elizabeth J Glover

“…Rats underwent three weeks of intermittent-access two-bottle choice home cage drinking before being trained to lever press for ethanol in standard operant chambers equipped with contact lickometers. …”
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Benchmarking LLM chatbots’ oncological knowledge with the Turkish Society of Medical Oncology’s annual board examination questions by Efe Cem Erdat, Engin Eren Kavak

“…This study aims to evaluate and compare the oncological knowledge of four LLMs using standardized board examination questions. Methods We assessed the performance of four LLMs—Claude 3.5 Sonnet (Anthropic), ChatGPT 4o (OpenAI), Llama-3 (Meta), and Gemini 1.5 (Google)—using the Turkish Society of Medical Oncology’s annual board examination questions from 2016 to 2024. …”
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Side Effects and Patient Tolerance with the Use of Blood Flow Restriction Training after ACL Reconstruction in Adolescents: A Pilot Study by Jennifer Prue, Dylan P Roman, Nicholas G Giampetruzzi, Arthur Fredericks, Adel Lolic, Allison Crepeau, J. Lee Pace, Adam P Weaver

“…Patients utilized an automatic personalized tourniquet system and followed a standardized BFRT exercise protocol over 12 weeks starting 8.72 ± 3.32 days post-op. …”
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Estimation of Non-Marine Fractions of Ions in Rainwater at Three Sites of Different Characteristics in Haryana State (India) by Yogender Singh, Ankita Katoch, Sudesh Yadav, Saurabh Dhakad, Umesh Chandra Kulshrestha

“…Calculation of ratios of major ions to Na+ to compare the standard Na+ ratios of seawater at all the sites indicated a significant influence of non-marine sources. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Statistical Analysis: Mean, standard deviation, frequencies, and percentages were calculated for baseline characteristics. …”
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Impact of tourist and recreational activities on the indicators of soil-ecological monitoring of the adjacent territory of Lake Teletskoe (Altai Mountains) by Olga A. Elchininova

“…The content of nutrients and lead were within the background and did not exceed the standardized values. The detected high concentrations of arsenic were not associated with the influence of tourist and recreational activities. …”
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Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

“…Therefore, we planned a study with an objective of evaluating safety, tolerability, pharmacodynamics and pharmacokinetics of a novel thienopyridine antiplatelet agent AT-10 in healthy Indian subjects compared with standard dosage regimen of clopidogrel based on their CYP2C19 genotyping.Methods Two CYP2C19 genotype–based groups were identified, that is, poor metabolisers and extensive metabolisers, with 20 subjects in each group (n=40) for participating in a randomised, two-period, crossover study. …”
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Characteristics and outcomes of the screening program of autism spectrum disorder in Primary Healthcare Centers in Bahrain by Muna A. Almohri, Mahmood A. Alawainati, Zahra A. Ayoob, Nayla A. Nasser, Noof A. Abdulaal, Ahmed A. Aldailami, Donya A. Aldailami

“…SPSS version 25.0 was used for data analysis; mean and standard deviation were calculated for continuous variables, and categorical variables presented as frequency and percentage. …”
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Analytical Approach to the Selection of Research Topics for Gallstone Disease and Acute Cholecystitis (an Overview of Cochrane Reviews) by S. I. Panin, T. V. Nechay, A. V. Sazhin, A. V. Puzikova

“…In the context of bile duct injury between early and delayed laparoscopic cholecystectomy, number of complications between early and delayed laparoscopic cholecystectomy, small-incision cholecystectomy and laparoscopic cholecystectomy, single-port and standard four-ports cholecystectomy and low-pressure laparoscopy the required size of meta-analysis information is unlikely to be achieved — in current versions of Cochrane library DARIS is less than 1 % of required. …”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…The qPCR-based methods displayed 100% agreement with the standard genotyping outcomes. When the PCR-electrophoresis method was used, approximately 15% of the samples required re-examination to obtain conclusive results. …”
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The effect of magnesium supplementation on serum concentration of lipid profile: an updated systematic review and dose-response meta-analysis on randomized controlled trials by Mitra Hariri, Masoudreza Sohrabi, Ali Gholami

“…Following fulfilling the first aim, their mean differences and standard deviations were calculated to conduct the meta-analysis. …”
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Attitudes towards transjugular intrahepatic portosystemic shunt (TIPS) in Australia: a national survey of TIPS centres by Jacob George, Avik Majumdar, Golo Ahlenstiel, Stuart K Roberts, Scott Read, Eric Kalo

“…This study aimed to address this gap in knowledge and benchmark the current landscape of TIPS services in Australia against international guidelines.Methods We designed a 42-item questionnaire according to practice-based recommendations and standards of international guidelines to investigate current landscape of TIPS service across four key domains: (1) service provision, (2) patient selection and indications, (3) best procedure practice, and (4) postoperative care.Results Gastroenterologist/hepatologists from 23 major liver centres (67.6%) across Australia currently performing TIPS completed the questionnaire. …”
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Automatic three-dimensional reconstruction of the oesophagus in achalasia patients undergoing POEM: an innovative approach for evaluating treatment outcomes by Alanna Ebigbo, Helmut Messmann, Vivian Grünherz, Miriam Elia, Alessandra Brunner, Tamara Krafft, Leo Pöller, Pia Schneider, Fabian Stieler, Bernhard Bauer, Anna Muzalyova, Sandra Nagl

“…Background and aims Peroral endoscopic myotomy (POEM) is a standard treatment option for achalasia patients. Treatment response varies due to factors such as achalasia type, degree of dilatation, pressure and distensibility indices. …”
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Gasoline Direct Injection Engine Emissions of OC and EC: Laboratory Comparisons with Port Fuel Injection Engine by Jie Zhang, John Liggio, Tak W. Chan, Lin Huang, Jeffrey R. Brook

“…Abstract To better understand carbonaceous aerosol emissions from gasoline vehicles, a gasoline direct injection (GDI) vehicle with and without a gasoline particle filter (GPF) installed and a port fuel injection (PFI) vehicle were tested on a chassis dynamometer using standard emission drive cycles. Carbonaceous particles emitted from the vehicles were collected on quartz filters and analyzed using three different thermal optical protocols to assess the sensitivity of organic carbon (OC) and elemental carbon (EC) emission estimates to the methods, showing OC obtained by the IMPROVE and EC by the NIOSH protocol was the lowest. …”
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Cardiopulmonary fitness in children/adolescents with chronic kidney disease and the impact of exercise training: a systematic review and meta-analysis of observational study and ra... by Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong

“…The studies found that the mean cardiopulmonary fitness was 1.82 standardized mean differences (SMDs) units (95% confidence interval (95% CI) 1.43–2.20) lower in children/adolescents with CKD than in healthy controls or reference values. …”
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The language use Inventory-Persian: report of the psychometric properties by Mahbubeh Nakhshab, Ali Asgary, Akram Ahmadi

“…We pursued the steps of translation and adaptation of this questionnaire into Persian according to a standard guideline. Then, 348 parents/caregivers of three groups of children consisting of typically developing (TD), late-talking children, and ones with autism spectrum disorders (ASD) 18-47-month-old Persian-speaking children completed the adapted version of the LUI. …”
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Expected annual minima from an idealized moving-average drought index by J. H. Stagge, K. Sung, K. Sung, I. F. Munyejuru, M. A. I. Haidar

“…<p>Numerous drought indices originate from the Standardized Precipitation Index (SPI) and use a moving-average structure to quantify drought severity by measuring normalized anomalies in hydroclimate variables. …”
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Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center by Rhodri Saunders, Carlo Calabrese, Dania Gelli, Jason Davis, Rafael Torrejon Torres

“…**Objective:** To validate a Crohn's disease model estimating the budget impact of VCE compared with the standard of care (SOC) in Italy. **Methods:** A patient-level, discrete-event simulation was developed to estimate the budget impact of VCE compared with SOC for Crohn's disease surveillance over 5 years in the Italian setting. …”
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Worth the effort? A practical examination of random effects in hidden Markov models for animal telemetry data by Brett T. McClintock

“…I generally found mixed HMMs did not improve state assignment relative to standard HMMs. Reliable estimation of random effects required larger sample sizes than are often feasible in telemetry studies. …”
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