Autosplenectomy in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) by Ethan Burns, Kartik Anand, Gonzalo Acosta, Malcolm Irani, Betty Chung, Abhishek Maiti, Ibrahim Ibrahim, Lawrence Rice

“…Splenic ultrasonography demonstrated an atrophic spleen with multifocal scarring, and absent splenic uptake of liver-spleen scintigraphy, consistent with AS. …”
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Indications, Surgical Technique and Outcomes of Laparoscopic Splenectomy: A Retrospective Descriptive Study from Srinagar, India by Mushtaq Chalkoo, Mudasir Habib, Ashiq Hussain Raina, Firdous Hamid, Sajad Nazir Malla, Imtiyaz Ahmad Malik

“…Aim: To assess the indications and outcomes of laparoscopic splenectomy across a range of spleen sizes, from normal to massively enlarged spleens, in a tertiary care hospital. …”
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Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2 by Jiaqi Sheng, Depei Wu, Jingzhe Shang, Xiaodan Fu, He Gao, Jianjie Rong, Jun Wang, Jiancheng Hu, Xiaofei Qi

“…Our findings indicated that Usp11−/− mice exhibited improved survival rates following TBI, with the spleen playing a pivotal role. HE staining revealed a wider marginal zone in the spleen of Usp11+/+ mice post-irradiation. …”
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Regulatory Role of rno-miR-30b-5p in IL-10 and Toll-like Receptor 4 Expressions of T Lymphocytes in Experimental Autoimmune Uveitis In Vitro by Yuanyuan Sun, Dadong Guo, Bin Liu, Xuewei Yin, Huixia Wei, Kai Tang, Hongsheng Bi

“…Meanwhile, the levels of rno-miR-30b-5p in eye tissues, spleen, and lymph nodes were measured using quantitative PCR (Q-PCR). …”
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Simultaneous Huge Splenic and Mesenteric Hydatid Cyst by Mostafa M. Abdelmaksoud, Alaa Jamjoom, Mohamed T. Hafez

“…After performing imaging studies, he was diagnosed with a simultaneous huge spleen and pelvic mesentery hydatid cyst that was managed surgically by splenectomy, pelvic mesenteric cyst deroofing, and partial cystectomy.…”
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

“…Results At baseline [11C]NES uptake was found in the bone marrow, spleen and liver. The uptake in the bone marrow was markedly increased two hours into the sepsis, whereas in spleen and liver the uptake was not as markedly changed compared to baseline. …”
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Gambaran Kadar Trombosit, Besar Limpa dan Kadar Albumin Serum pada Pasien Sirosis Hati dengan Varises Esofagus by Vella Paraditha, Saptino Miro, Eti Yerizel

“…There was no significant difference in spleen size between patients with first, second, or third degree esophageal varices. …”
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Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan... by Mohamed A. Lebdah, Amal A. M. Eid, Reham M. ElBakrey, Abd Elgalil. El-Gohary, Mohamed G. Seadawy, Mohamed R. Mousa, Hagar F. Gouda, Nehal I. A. Goda, Mostafa F. El-Hosseny, Ahmed S. El-tahlawy, Rokayya Sami, Rasha A. Al-Eisa, Sarah S. Helal

“…For this purpose, 99 ducks (25 flocks) of different breeds, aged 14–75 days, were clinically examined, and 75 tissue pools from the thymus, bursa of Fabricius, and spleen were submitted for virus detection and identification. …”
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Splenic Stromal Cells from Aged Mice Produce Higher Levels of IL-6 Compared to Young Mice by Jihyun Park, Takuya Miyakawa, Aya Shiokawa, Haruyo Nakajima-Adachi, Masaru Tanokura, Satoshi Hachimura

“…We compared IL-6 production in spleen cells from both young and aged mice and isolated several types of cells from spleen and investigated IL-6 mRNA expression and protein production. …”
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Endometrial Regenerative Cell-Derived Conditioned Medium Alleviates Experimental Colitis by Chenglu Sun, Jingpeng Hao, Hong Qin, Yanglin Zhu, Xiang Li, Baoren Zhang, Yafei Qin, Guangming Li, Hongda Wang, Hao Wang

“…ERC-CM increased the percentage of Tregs in the spleen and colon but decreased the percentages of M1 macrophages and Th1 and Th17 cells in the spleen and decreased the population of Th17 cells in the colon. …”
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Diagnosis of Splenic Lymphoma by Endoscopic Ultrasound Guided Fine Needle Aspiration: A Case Report and Review of the Literature by Umar Darr, Zubair Khan, Muhammad Ali Khan, Anas Renno, Turki Alkully, Sehrish Kamal, Tariq Hammad, Yaseen Alastal, Muhammad Imran Khan, Ali Nawras

“…She underwent CT scan of abdomen which revealed approximately 5 cm × 5 cm mass in spleen. EUS-FNA of the spleen revealed a large hypoechoic, heterogeneous, well-demarcated mass measuring 54.7 mm × 43.0 mm. …”
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Gambaran Kadar Trombosit, Besar Limpa dan Kadar Albumin Serum pada Pasien Sirosis Hati dengan Varises Esofagus by Vella Paraditha, Saptino Miro, Eti Yerizel

“…<br />Keywords: platelet count, spleen size, albumin level, esophageal varices degree…”
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Splenorenal Manifestations of Bartonella henselae Infection in a Pediatric Patient by Taylor Rising, Nicholas Fulton, Pauravi Vasavada

“…Subsequent ultrasound imaging demonstrated multiple hypoechoic foci within the spleen. A contrast-enhanced CT of the abdomen and pelvis was also obtained which showed hypoattenuating lesions in the spleen and bilateral kidneys. …”
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Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness by Qiufang Ouyang, Ziyang Huang, Zhenhua Wang, Xiaoqing Chen, Jingqin Ni, Ling Lin

“…And the expression of T-bet/GATA-3 and IL-12/IL-10 mRNA in spleen were analyzed by real-time PCR. We found that pristane treatment for a period of 12 or 24 weeks triggered macrophage activation syndrome, characterized by hemophagocytosis in spleen and peripheral blood, enhanced lipid phagocytosis by peritoneal macrophages in vitro, erythropenia and leucopenia, increased anti-Smith, lactic dehydrogenase, triglyceride, and ferritin, as well as hypercytokinemia of IFN-γ, TNF-α, IL-4, and IL-6. …”
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Cytokine Detection and Modulation in Acute Graft vs. Host Disease in Mice by A. C. Knulst, G. J. M. Tibbe, C. Bril-Bazuin, E. G. Breedland, A. van Oudenaren, R. Benner, H. F. J. Savelkoul

“…Lethally irradiated (C57BL × CBA)F1 mice were reconstituted either with 107 allogeneic BALB/c spleen cells or with a similar number of syngeneic cells, as a control. …”
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Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs by Murat Köse, Ersida Buraniqi, Timur Selçuk Akpinar, Seyit Mehmet Kayacan, Tufan Tükek

“…In addition to renal failure, anemia, hypercalcemia, lytic bone lesions, and immunodeficiency, it also affects multiple organ system, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, lymph nodes, and bone. To raise awareness of the variable presentations of this disease, we report a 53-year-old male patient, with multiple myeloma in his first remission who relapsed with extramedullary plasmacytomas (EMPs) involving multiple organs, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, and lymph nodes.…”
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Portable devices for periodic monitoring of bioelectrical impedance along meridian pathways in healthy individuals by Yu-Chen Xu, Xiu-Yan Cao, Shuai Liu, Bo Liu, Hao Chen, Min Cheng, Wei-Hua Ye

“…The spleen meridian, in particular, appears to play a crucial role in influencing these bioelectrical fluctuations, as posited in TCM theory. …”
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Seventy-Day Toxicity Study in Juvenile Sprague-Dawley Rats with Semicarbazide (SEM) from Weaning to Sexual Maturity by Vijaykumar Malashetty, Raghunandan Deshpande, Somnathreddy Patil

“…Increased absolute and relative liver and spleen weight in both sexes were observed. Male rats had lower thymus and testes weights, whereas female rats had lower uterine weights. …”
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Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy by Beni Adegoke Adeniji, Moses Fallas, Marc Incerpi, Solomon Hamburg, Robert Katz, Dotun Ogunyemi

“…We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. …”
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Pathological Study of Blood Parasites in Rice Field Frogs, Hoplobatrachus rugulosus (Wiegmann, 1834) by Achariya Sailasuta, Jetjun Satetasit, Malinee Chutmongkonkul

“…Pathological examination of the liver, lung, spleen, and kidney of the frogs that were apparently infected with one of these blood parasites were collected and processed by routine histology and subsequently stained with haematoxylin and eosin. …”
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