Quantification of Cerenkov Luminescence Imaging (CLI) Comparable With 3-D PET Standard Measurements by Frezghi Habte PhD, Arutselvan Natarajan PhD, David S. Paik PhD, Sanjiv Sam Gambhir MD, PhD

“…After applying tissue attenuation correction and unit conversion to the in vivo animal study, an average quantification difference of 10% for spleen and 35% for liver was obtained compared to PET measurements. …”
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Synergistic Therapeutic Effects and Immunoregulatory Mechanism of Maxing Shigan Decoction Combined with Sijunzi Decoction on Viral Pneumonia in Mice by Huimin Huang, Huanhua Yang, Zurong Zhang, Yunlong Song, Li Li, Ke Li, Junjie Zhang, Xiaoyu Qi, Ying Wu

“…Si Jun Zi Tang (SJZD) is recognized as one of the “Fu Zheng” formulas for strengthening the spleen and nourishing the stomach, with immunomodulatory effects. …”
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The systemic immune state of super-shedder mice is characterized by a unique neutrophil-dependent blunting of TH1 responses. by Smita Gopinath, Andrew Hotson, Jennifer Johns, Garry Nolan, Denise Monack

“…Compared to moderate shedders, super-shedder mice had an active inflammatory response in both the gastrointestinal tract and the spleen but a dampened T(H)1 response specific to the secondary lymphoid organs. …”
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Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats by P. O. Yusuf, G. Ada, D. B. Nuhu, S. Dahiru, P. M. Ameh, M. Mamman, M. U. Kawu, M. Bisallah, S. J. Enam

“…These findings suggest the venom of Echis ocellatus induces significant hematotoxicity, with pathological involvement of the heart, liver, kidneys, and spleen. …”
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ALLERGIC RHINITICAL THERAPY WITH ACUPUNCTURE, LEGUNDI AND TEMULAWAK HERBS by Maya Septriana, Novita Purnamasari, Herra Studiawan

“…Acupuncture therapy was carried out at Yintang point (EXHN 3), Yinxiang (LI 20), Zusanli (ST 36), Taibai (SP 3) with the principle of eliminating hot humidification and toning of the spleen. In herbal therapy, patients are given herbal legundi (Vitex trifolia) and ginger (Curcuma xanthorrhiza). …”
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Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout by Mari Raudstein, Ma. Michelle D. Peñaranda, Erik Kjærner-Semb, Søren Grove, H. Craig Morton, Rolf Brudvik Edvardsen

“…Gene expression analyses demonstrated significantly reduced membrane-bound IgM mRNA levels in head kidney and spleen tissues. Flow cytometry revealed a 78% reduction in IgM+ B cells in peripheral blood, and Western blot analyses showed decreased IgM protein levels in serum. …”
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BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens by Amanda Contreras, Darin L. Wiesner, Brock Kingstad-Bakke, Woojong Lee, John P. Svaren, Bruce S. Klein, M. Suresh

“…However, Bach2 deficiency in Tregs led to augmented expressions of IRF4, BATF, and GATA3 and a significant increase in the accumulation of ST2 (IL-33R)+ve effector Tregs in the spleen and visceral adipose tissue (VAT) but not in the lungs. …”
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An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…A group of D-gal-treated mice treated at 400 mg/kg/day UP360 was kept without vaccination. Whole blood, serum, spleen homogenate, and thymus tissues were used for analysis. …”
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Effect of Quercetin on Bone Mineral Status and Markers of Bone Turnover in Retinoic Acid-Induced Osteoporosis by Oršolić Nada, Jeleč Željko, Nemrava Johann, Balta Vedran, Gregorović Gordana, Jeleč Dražen

“…We analysed changes in body and uterine weight of animals, femoral geometric characteristics, calcium and phosphorus content, bone weight index, bone hystology, bone mineral density (BMD), markers of bone turnover, lipid peroxidation, glutathione levels and SOD, CAT activity of liver, kidney spleen, and ovary as well as biochemical and haematological variables. …”
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Construction and Evaluation of a Subcutaneous Splenic Injection Port for Serial Intraportal Vein Cell Delivery in Murine Disease Models by Toshio Miki, Chika Takano, Irving M. Garcia, Brendan H. Grubbs

“…Here, we propose a surgical model that utilizes the spleen as a subcutaneous injection port. Mouse spleens were translocated under the skin with intact vascular pedicles. …”
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Maltoma of Thyroid: A Rare Thyroid Tumour by Navisha Latheef, Vijendra Shenoy, M. Panduranga Kamath, Mahesh Chandra Hegde, A. Raghavendra Rao

“…Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. A case of maltoma of thyroid is presented for its rarity and diagnostic dilemmas. …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. …”
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The Nod2 Agonist Muramyl Dipeptide Cooperates with the TLR4 Agonist Lipopolysaccharide to Enhance IgG2b Production in Mouse B Cells by Sang-Hoon Lee, Jong-Hwan Park, Seok-Rae Park

“…In the present study, we examined the effect of the Nod2 agonist muramyl dipeptide (MDP) in combination with the TLR4 agonist lipopolysaccharide (LPS), a well-known B cell mitogen, on B cell viability, proliferation, and activation, and Ab production by in vitro culture of purified mouse spleen resting B cells. MDP combined with LPS to reinforce B cell viability, proliferation, and activation. …”
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RESULTS OF EXPERIMENTAL INFECTION OF TURKEYS WITH A/DUCK/ALTAI/469/14 H5N1 STRAIN OF AVIAN INFLUENZA VIRUS by V. Yu. Sosipatorova, D. A. Altunin, I. A. Chvala, N. S. Mudrak, D. B. Andreychuk

“…Inflammatory and necrotic lesions of varying severity are detected in the preparations of the trachea, lung, muscular stomach, glandular stomach, small intestine, large intestine, pancreas, brain, cerebellum, heart, kidneys, liver and spleen of turkeys. Immunohistochemical analysis showed the greatest distribution of the influenza virus antigen in the cerebral endothelium, cerebellar Purkinje neurons, acinar cells of the pancreas and in myocardiocytes of the heart. …”
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Radix Codonopsis: a review of anticancer pharmacological activities by Cai-Yue Liu, Zheng Li, Fan-E. Cheng, Yi Nan, Yi Nan, Wei-Qiang Li, Wei-Qiang Li

“…It is renowned for its pharmacological effects, including tonifying the middle qi, invigorating the spleen, benefiting the lungs, enhancing immunity, and nourishing the blood. …”
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Nursing of a lung cancer patient with insomnia treated with five-element energy cupping therapy (1例肺癌伴失眠患者行五行能量罐疗法的护理体会) by YAN Kang (严康), LIU Shuhong (刘书红), ZHAO Yanan (赵亚楠)

“…This paper reviewed the clinical effect of five-element energy cupping therapy in the treatment of heart-spleen deficiency type insomnia in a lung cancer patient, and summarized related nursing measures. …”
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Characterization of Human Colorectal Cancer MDR1/P-gp Fab Antibody by Xuemei Zhang, Gary Guishan Xiao, Ying Gao

“…Phage-displayed antibody library prepared from mice spleen tissues was selected against the recombinant protein P-gp21 with five rounds of panning. …”
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Point of Care Perioperative Coagulation Management in Liver Transplantation and Complete Portal Vein Thrombosis by Cristiano Piangatelli, Lucia Faloia, Claudia Cristiani, Ilaria Valentini, Marco Vivarelli

“…Macroscopic liver and spleen adherences with collateral circulation were evident. …”
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ANALYSIS OF THE INTRAOPERATIVE ULTRASOUND RESULTS IN THE SURGICAL TREATMENT OF RENAL TUMORS by A. D. Karnin, A. A. Kostin, S. O. Stepanov, N. V. Vorobyev, P. D. Bespalov, V. O. Dimitrov

“…The frequency of damage to the spleen and the transition to open surgery did not differ. …”
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ABNORMAL BLOOD LIPIDS LEVELS (DYSLIPIDEMIA) TREATMENT WITH ACUPUNCTURE METHOD by Anissa Maulina Rinjani, Lilik Herawati, Maya Septriana

“…The result there were 20 journals consisting of studies that used several acupuncture methods, manual acupuncture (AM), electroacupuncture (EA), moxa (MOK), auricular acupuncture (AA), Cupping (CUP), and found additional interventions such as nutritional interventions, and exercise; body points often used are Zusanli (ST 36), Fenglong (ST 40), Quchi (LI 11), Daheng (SP15), Zhongwan (CV 12), Qihai (CV 6), Guanyuan (CV 4), Sanyinjiao (SP 6), Shenque (CV 8), Tianshu (ST 25), and therefore for AA are Spleen (CO 13), Stomach (CO 4), Shenmen (TF 4), and hunger point. …”
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