Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells by Na Tian, Cui Yang, Yu Du, Miao Chen, Bin Li, Bin Li, Bin Li, Bin Li, Bin Li, Dan Li, Sheng-Ming Dai

“…AIA mice were treated with HU-308 or vehicle, and effects on paw swelling, spleen index, histopathology, and immune cell profiles were evaluated. …”
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Granulocyte Colony Stimulating Factor (G-CSF) Induced Splenic Infarction in Breast Cancer Patient Treated with Dose-Dense Chemotherapy Regimen by Majed A. Alshamrani, Meteb Al-Foheidi, Ahmed H. Abdulrahim

“…It is considered an effective and relatively safe supportive care medication; however, it can cause rare and serious side effects such as spleen rupture or infarction. Case Presentation. We are reporting a case of a 27-year-old female with breast cancer who has been treated with dose-dense chemotherapy and received colony-stimulating factor as primary prevention of febrile neutropenia that was complicated halfway through with splenic infarction. …”
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Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso by A. P. Duzanski, A. D. Ortiz, H. B. Fêo, M. W. Fonseca, M. M. Flórez, L. T Rodrigues, F. Michelon, N. S. Rocha

“…We describe herein a genital mixed TVTC case with metastases at spleen and failure at vincristine sulfate chemotherapeutic treatment in a five years old Australian Cattle Dog female. …”
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TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease by Sara Jarmakiewicz-Czaja, Aneta Sokal, Jacek Tabarkiewicz, Rafał Filip

“…It demonstrates the ability to accumulate in some internal organs, like spleen, liver, and kidneys, depending on its size and structure. …”
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Poète en morceaux, morceaux de poète by Amalia Dragani

“…As regards the former there is talk of “bodies in pieces, boiling, explosion” and emotional disorders that affect the internal organs such as the liver, heart, spleen and bowels. Moreover for “flesh-and-blood” poets, creation is essentially reflected in effects on the skin (e.g. goose bumps) and “small hairs and downs” (bristling), therefore on external organs. …”
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Isolated Splenic Hydatid Disease by Alper Dilli, Idil Güneş Tatar, Umit Yasar Ayaz, Baki Hekimoglu

“…The involvement of the spleen in HD is rare, and isolated splenic involvement is even less common. …”
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Free Radical Scavenging Capacities and Alleviating Actions of Polysaccharides Extract of Termitomyces le-testui on Methylprednisolone-Induced Immunodepression in Rats by Foncham Evans Ngwenah, Kada Sanda Antoine, Salah Martin, Tume Christopher, Oumar Mahamat

“…The result of the study showed that the polysaccharide T. le-testui increases the phagocytic index, energy metabolism of macrophages, spleen index, and nitric oxide in a concentration-dependent manner in immunosuppressed animals. …”
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Transient Complete Recovery of Chronic Refractory Idiopathic Thrombocytopenic Purpura after Treatment with Monoclonal Antibody Targeting SARS-CoV-2 Spike Protein by Pooja Gogia, Yiqing Xu

“…Therapy for ITP relies on competing and inhibiting the autoantibody binding and destruction (intravenous immunoglobulin and anti-D immunoglobulin and spleen tyrosine kinase (Syk) inhibitor fostamatinib), augmenting platelet production (thrombopoietin receptor agonists), immunosuppression to reduce the autoantibody production, as well as splenectomy. …”
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The Discovery of Novel Experimental Therapies for Inflammatory Arthritis by Charles J. Malemud

“…Over the past few years, sphingosine-1-phosphate, interleukin-7 receptor, spleen tyrosine kinase, extracellular signal-regulated kinase, mitogen-activated protein kinase 5/p38 kinase regulated/activated protein kinase, micro-RNAs, tumor necrosis factor-related apoptosis inducing ligand and the polyubiquitin-proteasome pathway were identified as promising novel targets for potential antiarthritis drug development. …”
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The determination of the selenium levels in the blood and tissues of mice given selenium by İbrahim Pirinçci, Ahmet Ateşşahin, İzzet Karahan, İrfan Demirbaş

“…Whereas, when it was intraperitoneal^ given, the selenium levels were defined to reach to the maximum levels in blood at 10 and 30th min; in liver at 30th min and 2 nd hours; in kidney at 1st hour; in spleen at 15 and 30th min; in heart at 10 and 15th min; in muscle at 24 and 8th hours according to doses, respectively. …”
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Histopathological and Immunohistochemical Evaluation of African Swine Fever Pigs in Bali Province by Monica Septiani, Vetnizah Juniantito, Bambang Pontjo Priosoeryanto

“…Immunohistochemistry consistently showed p54 viral antigen distribution in mononuclear cells/macrophages across various organs, with the spleen and lymph nodes being dominant sites in 12 pigs (100%). …”
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Primary Pleomorphic Liposarcoma of Liver: A Case Report and Review of the Literature by P. R. Thippeswamy Naik, Prem Kumar, P. Vinod Kumar

“…CT abdomen showed a heterogenous enhancing mass from left lobe of liver with multiple cystic and necrotic areas compressing the stomach and spleen with no evidence of metastasis. Differential diagnosis included adenoma and primary malignancy. …”
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The effects of the varying filling degrees of the stomach on the topographies of the kidneys in cat by Emrullah Eken, Memduh Gezici

“…This investigation is different from that of Deniz and Klesty in that transversal cross sectiones of the abdominal cavity were done alter the materials were deep Ireezed; the topographies of the left and right kidneys, and their relations with the other organs were determined; following dissection the photographes of mentioned organs were taken: it was detected that the kidneys were retroperitoneally situated, yellow-red and bean shaped: generally, the right kidney was in front of the left one, but it was contrary to this stuation in one material, the kidneys were displaced aboul one vertebrae lenght in caudal, cranial and dorsal direction depending on the filling degrees ol the stomach, the left kindney was adjacent to the descendent colon and left pancreatic lobe ventromedially, the spleen cramally. the psoas muscles dorsally, the left ovary (in female) caudally, the right kidney was ad|acent to the caudal process and rigt lateral hepatic lobe craniatly, the psoas muscles dorsally, the beginning portion of descendent part of duodenum ventromedial^ and the right ovary caudally.…”
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Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model by Ngoc Buu Tran, Sook-Jeong Lee

“…The results demonstrated that increasing intracellular Zn2+ levels ameliorate deficits in motor behavior, as well as inflammation in the paw, spleen, and thymus. Furthermore, intracellular Zn2+ was crucial in regulating oxidative stress markers (glutathione, superoxide dismutase, catalase, and malondialdehyde) and inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, in MT3 knockout mice induced with CFA. …”
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Partial Ureteropelvic Junction Disruption after Blunt Trauma: Case Report by Jalal Eddine El Ammari, Youness Ahallal, Mohammed Jamal El Fassi, M. Hassan Farih

“…Emergency celiotomy was performed for massive hemoperitoneum and shattered spleen which led to splenectomy. The diagnosis of partial UPJ disruption was missed preoperatively and suspected in CT scan after appearance of flank tender mass. …”
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The effectiveness of inactive arcanobacterium pyogenes vaccines in mice by Hasan Hüseyin Hadimli*, Zafer Sayın, Yasemin Pınarkara, Aslı Sakmanoğlu, M. Seyyide Temimhan, Osman Erganiş

“…Death animals were necropsied and microbiological examination were made from internal organs (liver, spleen, lungs, heart and kidney). Blood samples were collected before vaccination and at 15th day after vaccination. …”
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Clinicopathologic profile of intra-abdominal follicular dendritic cell sarcoma: A study of three cases with a literature review by Jianhong Yan, Qi Wu, Yuchang Hu, Ting Nai

“…The mesentery of the small intestine and colon was involved in case 1, spleen in case 2, and retroperitoneal tissues in case 3. …”
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Emergency Splenectomy in a patient with primary immune thrombocytopenia and hemoperitoneum by Liermis Michael Dita Salabert, José Eduardo Consuegra Díaz, Carlos Jaime Geroy

“…An early clamping of the splenic artery, evacuation of the hemoperitoneum, left adnexectomy, splenectomy and resection of accessory spleen were performed. The patient progressed satisfactorily.…”
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Secondary Hemophagocytic Syndrome: The Importance of Clinical Suspicion by Cristina Oliveira, Sérgio Chacim, Isabel Ferreira, Nelson Domingues, José Mário Mariz

“…Clinically, patients present signs of severe inflammation, with unremitting fever, cytopenias, spleen enlargement, phagocytosis of bone marrow elements, hypertriglyceridemia, and hypofibrinogenemia. …”
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A rapid change in virulence gene expression during the transition from the intestinal lumen into tissue promotes systemic dissemination of Salmonella. by Sebastian E Winter, Maria G Winter, Ivan Godinez, Hee-Jeong Yang, Holger Rüssmann, Helene L Andrews-Polymenis, Andreas J Bäumler

“…TviA-mediated flagellin repression enabled bacteria to evade sentinel functions of human model epithelia and resulted in increased bacterial dissemination to the spleen in a chicken model. Collectively, our data point to PAMP repression as a novel pathogenic mechanism to overcome the mucosal barrier through innate immune evasion.…”
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