Primary Hairy Cell Leukemia/Lymphoma of the Breast: A Case Report and Review of the Literature by Monika Pilichowska, Ahmad Shariftabrizi, Ian Mukand-Cerro, Kenneth Miller

“…Hairy cell leukemia/lymphoma (HCL) is a rare B-cell neoplasm primarily involving spleen, bone marrow, and blood. However, other sites of primary involvement do occur and can present a diagnostic and therapeutic challenge. …”
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Struggling with a Gastric Volvulus Secondary to a Type IV Hiatal Hernia by Dafnomilis George, Pappas V. Apostolos, Panoutsopoulos Athanasios, Lagoudianakis E. Emmanuel, Koronakis E. Nikolaos, Panagiotopoulos Nikolaos, Seretis Charalampos, Karanikas George, Manouras J. Andreas

“…Type IV hiatal hernias are characterized by herniation of the stomach along with associated viscera such as the spleen, colon, small bowel, and pancreas through the esophageal hiatus. …”
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The endogenous hydrogen gas (H2) drives women’s health: a comment on “Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas” by Shuangling Yang, Jiongshan Zhang, Luyao Xu, Yajie Guan, Chun Fang, Shuhui Zheng, Hongzhi Yang, Haimei Liu, Haimei Liu, Yaxing Zhang, Yaxing Zhang

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Nucleotide-Binding Oligomerization Domain-1 and -2 Play No Role in Controlling Brucella abortus Infection in Mice by Fernanda S. Oliveira, Natalia B. Carvalho, Dario S. Zamboni, Sergio C. Oliveira

“…However, NOD1, NOD2, and Rip2 knockout mice were no more susceptible to infection with virulent B. abortus than wild-type mice. Additionally, spleen cells from NOD1-, NOD2-, and Rip2-deficient mice showed unaltered production of IFN-γ compared to C57BL/6 mice. …”
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Rare Presentation of Hypoglycemia in a Patient with Anaplastic Large-Cell Lymphoma by Raed Aldahash

“…Its presentation by extending into different organs such as the liver, lungs, bones, spleen, and thyroid is rare. Thus, involvement of other organs is very rare as we found in a 54-year-old male patient, a known case of hypertension and end-stage renal disease who was on hemodialysis, who presented to the emergency department with a history of generalized weakness and weight loss of about 20 kg for two months. …”
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Therapeutic effects of epigallocatechin and epigallocatechin gallate on the allergic reaction of αs1-casein sensitized mice by Qianqian Zhang, Xiaofeng Yu, Linghan Tian, Yanjun Cong, Linfeng Li

“…The histopathology results showed that both EGC and EGCG markedly reduced the degree of lesions in the intestine, thymus, spleen, and lung. The conclusions from this study can provide a theoretical basis for the mechanism by which tea polyphenols regulate food allergens.…”
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Case of Solid Pseudopapillary Neoplasm of Pancreas by M. Hamzaçelebioğlu, O. Üreyen, A. Argon, E. İlhan, A. Mert Ateşci

“…In this study, we discuss the case of a 69-year-old woman diagnosed with an SPTP originating from the tail of the pancreas, which had spread to the hilum of the spleen. A radical resection was performed, successfully obtaining negative surgical margins. …”
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Imaging Findings of Gastric Diverticula by Dominik Schramm, Andreas Gunter Bach, Alexander Zipprich, Alexey Surov

“…On CT, GD presented as cystic lesions with a thin wall and an air fluid level, located behind the stomach between spleen, adrenal gland, and crus of the left diaphragm. …”
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Blocking Interleukin-33 Alleviates the Joint Inflammation and Inhibits the Development of Collagen-Induced Arthritis in Mice by Yan Li, Yeqin Fu, Huan Chen, Xiaojin Liu, Mingcai Li

“…Moreover, anti-IL-33 treatment significantly downregulated the production of IFN-γ, IL-6, IL-12, IL-33, and TNF-α in ex vivo-stimulated spleen cells. Together, our results indicate that the IL-33-neutralizing antibody may provide a therapeutic strategy for RA by inhibiting the release of proinflammatory cytokines.…”
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Hemophagocytic lymphohistiocytosis following enteric fever: A rare autopsy case report by Gwendolyn Fernandes, Pooja Mhashete, Pranav Pramod Patwardhan

“…On microscopy, the liver, spleen, bone marrow, and lymph nodes showed characteristic hemophagocytosis. …”
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Juvenile Myelomonocytic Leukemia in a Child: A Case Report of Palliative Chemotherapy and Literature Review Applied to Limited Resources Centers by Natharina Yolanda, Stefanus Gunawan, Max F. J. Mantik, Anjo J. P. Veerman

“…Four weeks after receiving 6-mercaptopurine, the white blood cell count decreased to 10.6 × 103/μL and the spleen size was half of the original size. The patient continued chemotherapy until week 15, chemotherapy was stopped, but 16 weeks after the diagnosis of JMML, he developed severe thrombocytopenia, endophthalmitis, and sepsis and passed away. …”
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Laparoscopic Resection of Pancreatic Tail Solid Pseudopapillary Tumour in a Young Male by W. G. P. Kanchana, R. A. A. Shaminda, K. B. Galketiya, V. Pinto, D. Walisinghe, S. Wijetunge, R. Heendeniya

“…He underwent laparoscopic resection of distal pancreatic tumour en bloc with spleen. Large tumour was noted originating from the body and tail of the pancreas with dilated veins surrounding the tumour. …”
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THERAPY LOW BACK PAIN WITH SWEDISH MASSAGE, ACUPRESSURE AND TURMERIC by Dyah Ayu Rhomandhoni Putri, Ario Imandiri, Rakhmawati Rakhmawati

“…Acupressure at the points of Shenshu (BL23), Dachangshu (BL25), Taixi (KI3), Taibai (SP3), Fenglong (ST40) with the principle of therapy of kidney and spleen tonification and elimination of cold moist pathogens. …”
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Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice by Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser

“…This was accompanied by a significant increase in relative monocyte and neutrophil counts and in spleen cellularity. Lamotrigine significantly inhibited ConA-induced splenocyte proliferation in vitro and it significantly inhibited IL-2 and TNF-α secretion in ConA-stimulated splenocytes. …”
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Study of african swine fevervirus reproduction in porcine primary bone marrow cell culture before and after cryopreservation by I. Yu. Zhukov, I. V. Shevchenko, N. N. Vlasova, A. A. Varentsova, B. L. Manin, O. S. Puzankova, V. L. Gavrilova, A. S. Igolkin

“…This paper presents data on the preparation of cells from porcine bone marrow, spleen, lymph nodes, kidneys and testicles used for African swine fever virus reproduction. …”
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Immunomodulatory effects of Lactiplantibacillus plantarum CCFM8661 + stachyose on cyclophosphamide-induced immunosuppression mice by Weiwei Ma, Hang Sun, Lian Lian, Lidong Guo, Yanyan Wang, Lili Huang

“…On day 28, 30 minutes after the final administration, the mice were euthanized to collect the thymus, spleen, serum, ileum, and feces for subsequent analysis of immune indicators, intestinal barrier function, serum cytokines, and intestinal microbiota.ResultsThe combination significantly improved immune organ atrophy, restored intestinal morphology, and normalized cytokine levels in immunosuppressed mice, indicating enhanced immune function. …”
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Peripherally Embolizing Aortic Thrombus: The Work-Up, Management, and Outcome of Primary Aortic Thrombus by Ramy Mando, Robert Gemayel, Ashish Chaddha, Julian J. Barbat, Elvis Cami

“…Computed tomography (CT) revealed an intraluminal polypoid filling defect arising from the isthmus of the aorta projecting into the proximal descending aorta and findings consistent with infarction of the spleen and right kidney. Infectious, autoimmune, hematologic, and oncologic work-up were all unyielding. …”
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Research note: Genetically diverse avian hepatitis E virus identified in chickens with hepatitis-splenomegaly syndrome in Guangdong Province, China by Xue-Lian Zhang, Yu-Qian Zhang, Chun-Hong Liu, Yan Ma, Shu-Jian Huang, Jian-Wei Shao

“…Avian hepatitis E virus (HEV) is recognized as the primary causative agent of big liver and spleen disease, hepatitis-splenomegaly syndrome, and hepatic rupture hemorrhage syndrome, resulting in substantial economic losses within the global poultry industry. …”
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miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response by Yuxiao Li, Ran An, Mingjin Wu, Jiayan He, Xiaoguang He

“…RT-qPCR was used to determine the level of miR-224-5p; western blot analysis was used to determine GATA3; ELISA was used to determine the levels of OVA-specific IgE, IFN-γ, IL-4, IL-5, and IL-13; flow cytometry was used to determine the differentiation of Th1 and Th2 cells; and HE and PAS staining was used to observe the histopathological alterations in the mouse nasal mucosa and spleen. Results. miR-224-5p was downregulated in nasal mucosa from mice with AR and an AR cell model. …”
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F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo by Heather L. Thompson, Nico van Rooijen, Bryce T. McLelland, Jennifer O. Manilay

“…In vivo depletion of host macrophages using clodronate-loaded liposomes improved the ESHP-derived hematopoietic chimerism in the spleen but not in the BM. F4/80+ macrophages demonstrated a striking propensity to phagocytose ESHP targets in vitro. …”
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