Methotrexate and Valproic Acid Affect Early Neurogenesis of Human Amniotic Fluid Stem Cells from Myelomeningocele by Vardine Sahakyan, Enrico Pozzo, Robin Duelen, Jan Deprest, Maurilio Sampaolesi

“…Myelomeningocele (MMC) is a severe type of neural tube defect (NTD), in which the backbone and spinal canal do not close completely during early embryonic development. …”
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MRSA Spinal Epidural Abscess as a Neurosurgical and Infectious Disease Emergency with Unresolved Antimicrobial Solution by James Ebot, W. D. Freeman, Robert Wharen, Mark Anthony Diaz, Claudia Libertin

“…We present the case of a 74-year-old man who hematogenously seeded his entire epidural spinal canal from C1 to sacrum with MRSA bacteria and remained infected even after maximal treatment with vancomycin and daptomycin. …”
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Spinal Nerve Root Haemangioblastoma Associated with Reactive Polycythemia by Eric K. C. Law, Ryan K. L. Lee, James F. Griffith, Deyond Y. W. Siu, Ho Keung Ng

“…The extramedullary spinal canal is an uncommon location for these tumours. …”
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Safety assessment of microwave ablation in sheep vertebral bodies by Hendricus Nijland, Jinwen Zhu, Thomas Kwee, Ding-Jun Hao, Paul Jutte

“…Since cortical insulation appears insufficient to protect the spinal canal from excess heat, MWA involves a risk of paralysis.…”
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UNSTABLE LUMBAR FRACTURE-DISLOCATION TREATED BY LONG SEGMENT POSTERIOR PEDICLE SCREW INSTRUMENTATION by Ferdiansyah Danang, Primadenny Ariesa Airlangga

“…Conclusion: Thoracolumbar fracture and dislocation fixation aim to restore alignment and stability, to reduce kyphotic deformity, and to decompress the spinal canal. The long segment pedicle screw instrumentation can resist the deforming force of thoracolumbar fractures and dislocations that will inevitably collapse into further kyphosis, resulting in a better outcome.…”
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Promising horizons in achondroplasia along with the development of new drugs by Keiichi Ozono, Takuo Kubota, Toshimi Michigami

“…Along with severe short stature, foramen magnum stenosis and spinal canal stenosis are major complications: the former leads to sleep apnea, breathing disorders, myelopathy, hydrocephalus, and sudden death, and the latter causes pain in the extremities, numbness, muscle weakness, movement disorders, intermittent claudication, and bladder-rectal disorders. …”
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An Unusual Case of Radicular Pain Caused by Bilateral Lumbar Synovial Cyst: A Case Report and Review of the Literature by David Ruiz-Picazo, José Ramírez-Villaescusa, Ana Verdejo-González

“…There are different treatment options that range from conservative management to interventions like image-guided epidural steroid injection or direct cyst puncture and finally to open or endoscopic spinal canal decompression and spinal bone fusion with/without instrumentation. …”
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The effectiveness of posterior Schanz screw system in the anatomical restoration of thoracolumbar vertebral burst fractures: A 10-year single-institution experience by Pietro Domenico Giorgi, Simona Legrenzi, Ye Youchen, Bove Federico, Giuseppe Rosario Schirò

“…Clinical outcomes (Oswestry Disability Index [ODI] and Visual Analog Scale [VAS]) and radiological parameters (sagittal alignment and spinal canal dimensions) were assessed with a minimum 2-year follow-up. …”
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Differential Gene Expression Analysis in a Lumbar Spinal Stenosis Rat Model via RNA Sequencing: Identification of Key Molecular Pathways and Therapeutic Insights by Jin Young Hong, Wan-Jin Jeon, Hyunseong Kim, Changhwan Yeo, Hyun Kim, Yoon Jae Lee, In-Hyuk Ha

“…Background/Objectives: Lumbar spinal stenosis (LSS) is a degenerative condition characterized by the narrowing of the spinal canal, resulting in chronic pain and impaired mobility. …”
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Prevalence and natural development of thoracolumbar kyphosis in achondroplasia: A systematic review and meta-analysis by Chady Omara, Rania A. Mekary, Carmen L.A. Vleggeert-Lankamp

“…Introduction: Thoracolumbar kyphosis (TLK) is a frequently reported spinal deformity in achondroplasia, which in combination with the characteristic narrow spinal canal in achondroplasia predisposes for symptomatic spinal stenosis. …”
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Traumatic Fracture: Dislocation of Cervicothoracic Junction—Grand Round Presentation of C7-T1 Instabilities and Different Instrumentation Techniques by Mohammad A. Alsofyani, Soufiane Ghailane, Sultan Alsalmi, Sreenath Jakinapally, Louis Boissière, Ibrahim Obeid, Jean-Marc Vital

“…Initial CT scan shows vertebral body fracture of T1 with retropulsion into the spinal canal and anteroposterior dislocation of cervicothoracic junction type C according to AOSpine subaxial injury. …”
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Hidden cause of paralysis: tight filum terminale in spinal cord injury without radiographic abnormality by Yi Yuan, Yi Yuan, Zong Jian An, Fei Gao, Zhi Hui Li, Wei Li Xu, Yong Sun

“…All four pediatric patients underwent laminectomy for spinal canal decompression along with resection of the filum terminale. …”
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Semi-vertebral column resection with preservation of posterior ligament complex for Kümmell’s disease: a case report by Tong-Hao Wang, Zhi Liu, Yong-Gang Tian, Guo-Yue Yang, Li-Qiang Han

“…Conclusion This new spine surgery could completely decompress the spinal canal and reduce the iatrogenic destruction of spinal stability, which might be helpful for the reconstruction and maintenance of spinal stability.…”
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Profile of Lumbar Spinal Stenosis Patients at Dr. M. Djamil Central Public Hospital from 2018-2022 by Inasa Faiza Akbar, Roni Eka Sahputra, Eka Fithra Elfi, Rizki Rahmadian, Dina Arfiani Rusjdi, Nelmi Silvia

“…Background: Lumbar Spinal Stenosis (LSS) is a pathological condition characterized by narrowing of the spinal canal in the lower back. In Indonesia, comprehensive data on LSS is currently unavailable. …”
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Impact of titanium mesh cage slotting width on anterior cervical corpectomy and fusion for compression cervical spondylosis with MRI T2WI hyperintensity: a one-year follow-up study by Rongguo Yu, Xiurong Yuan, Kangkang Huang, Tingkui Wu, Hong Wang, Chen Ding, Beiyu Wang, Hao Liu

“…Radiological outcomes included cervical lordosis (CL), functional spinal unit (FSU) height, transverse decompression range (TDR), spinal canal area (SCA), TMC alignment, and subsidence and fusion rates. …”
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Comparison of anterior versus posterior approach for the treatment of cervical compressive myelopathy due to ossification of the posterior longitudinal ligament by Amr A. A Gaber, Mohamad Alaa El-Din Habib, Mohamed AR AbdelFatah, Mostafa K. Ghobashy

“…It frequently occurs due to constriction of the cervical spinal canal. Cervical spondylotic myelopathy is the primary reason for spinal cord impairment in older individuals. …”
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Efficacy Analysis of Percutaneous Endoscopic Lumbar Discectomy Combined with PEEK Rods for Giant Lumbar Disc Herniation: A Randomized Controlled Study by Xiang Gao, Kaiying Tang, Yu Xia, Xun Zhang, Keran Wang, Zhengjian Yan, Yu Du, Liang Chen

“…This study describes a randomized controlled trial that assesses percutaneous endoscopic lumbar discectomy (PELD) combined with a polyetheretherketone (PEEK) rod in patients with GLDH (herniation affecting 50% of the sagittal diameter of the spinal canal) and reports the 2-year follow-up outcome. …”
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Mid- to long-term clinical outcomes of modified technique skip-level titanium plate fixation in cervical laminoplasty compared to continuous fixation by Shuo Feng, QiRui Zhu, Yang Sun, ZiYao Ding, Zhe Zhuang, Heng-Heng Yu, Ma-Ji Sun, Feng Yuan

“…The sagittal diameter of the spinal canal from C3 to C7 significantly increased (P < 0.05), but there were no significant differences in the improvement of C3, C5, and C7 between the two groups (P > 0.05). …”
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Bilateral synchronous UBE for unilateral laminotomy and bilateral decompression as a potentially effective minimally Invasive approach for two-level lumbar spinal stenosis by Yulin Zhao, Yingjun Guo, Xin Pan, Hao Li, Xianlei Gao, Haipeng Si, Wanlong Xu

“…Postoperative lumbar CT showed that the spinal canal and bilateral nerve roots were fully decompressed. …”
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