-
1481
RETRACTED ARTICLE: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells
Published 2023-10-01“…Enriched CSCs derived from MG63 and U2OS cells presented upregulated LRPPRC levels compared to parental cells (PCs), and LRPPRC knockdown markedly decreased the sphere-forming capacity. These findings demonstrate that LRPPRC knockdown decreased stemness in CSCs. …”
Get full text
Article -
1482
System of Administrative and Legal Regulation of the Status of the Cabinet of Ministers of Ukraine in the Field of Scientific, Research and Technical Activity in Ukraine
Published 2021-07-01“…Thus, the mechanism of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine can be presented as follows: – administrative and legal norms that determine the administrative and legal status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine, their sources; – principles of the activity of the Cabinet of Ministers of Ukraine in the sphere of administrative relations in the field of science and technology in Ukraine; – interpretation of administrative and legal norms regulating the administrative and legal status of the Cabinet of Ministers of Ukraine in the field of scientific and scientific and technical activities in Ukraine; – the nature of administrative and legal relations in the field of scientific, research and technical activities, the participant of which is the Cabinet of Ministers of Ukraine; – individual acts of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity; – forms of activity of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity as the participant of administrative and legal relations; – methods of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine; – administrative and legal regimes regulating the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine; – administrative procedures of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities; – efficiency of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity.…”
Get full text
Article -
1483
The issue of motivation for foreign languages learning in international research works: Scoping review
Published 2021-05-01“…Within these groups, the existing research trends and the most promising research areas were identified (for instance, the influence of peers on the motivational sphere of students). Amongst the numerous works investigating external (socio-economic) factors of influence, there is insufficient research on the influence of macro-political and macro-economic factors on the motivation for learning languages (for instance, foreign languages learning preferences). …”
Get full text
Article -
1484
DEVELOPMENT OF CLIP THINKING OF HIGHER EDUCATION STUDENTS IN INFORMATION ENVIRONMENT
Published 2024-02-01“…It was concluded that overcoming the cognitive deficit, the dominance of the sphere of abstract and logical thinking is possible under the condition of the appropriate construction of the training organization in the direction of the logical presentation of the educational material, its compliance with practical goals, the introduction of technologies aimed at educational interaction (the use of electronic discussions (forums), electronic mail, conferences, etc.), ensuring an individual approach to the organization of educational and cognitive activities, taking into account the motives, needs and opportunities of higher education seekers, the variability of the selection of IT learning technologies and their combination. …”
Get full text
Article -
1485
PEDAGOGICAL CONTENT THREE-FACTOR MODEL OF EDUCATING HIGH-SCHOOL STUDENTS FOR PROFESSIONAL ACTIVITIES
Published 2016-09-01“…The model described in the paper is considered on the example of the discipline «A foreign language in the professional sphere». The just described model was worked out for effective foreign language education process perceived as a part of professional high-school education. …”
Get full text
Article -
1486
INTRA-REGIONAL DIFFERENTIATION OF ENTREPRENEURSHIP OF MUNICIPALITIES OF THE ŚWIĘTOKRZYSKIE VOIVODESHIP IN TERMS OF SUSTAINABLE DEVELOPMENT IN 2010 AND 2020
Published 2024-12-01“…Municipalities within the sphere of influence of urban centres had favourable conditions for the development of entrepreneurship. …”
Get full text
Article -
1487
Issues of Defining Administrative and Tort Relations as an Object of Legal Research
Published 2020-06-01“…It has been concluded that there is a relatively separate area of relations – administrative and tort sphere among the variety of legal relations in Ukraine. …”
Get full text
Article -
1488
Relationship between motivational climate, anxiety and average mark in pre-service physical education teachers: a cross-sectional study based on structural equation modelling appro...
Published 2025-01-01“…Within the motivational sphere, the motivational climate determines whether a task is performed with an intrinsic or extrinsic. …”
Get full text
Article -
1489
Psychological and pedagogical readiness of a guide to work with disabled people
Published 2020-01-01“…The pedagogical aspects of such activities are not presented in the theory and practice of vocational training/retraining of personnel for the tourism sphere. The conclusion was reached that the methods of education in higher education institutions and the system of advanced training for specialists-guides need to be further developed and improved in order to maximise the implementation of pedagogical function of culture-oriented sightseeing tourism. …”
Get full text
Article -
1490
STABILITY OF DEVELOPMENT OF FUTURE PROFESSIONALS’ EMOTIONAL INTELLIGENCE
Published 2018-09-01“…The authors proved the importance of the high level of emotional intelligence for the modern person irrespective of the sphere of professional employment. The main zones of this type of intelligence and their structural components which should be developed in future experts were highlighted. …”
Get full text
Article -
1491
Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells
Published 2019-01-01“…To verify that our sphere cultures were enriched in CSC, we evaluated the double staining of CD49f and ALDH activity for HeLa cells by flow cytometry. …”
Get full text
Article -
1492
Microplastics in freshwaters: Comparing effects of particle properties and an invertebrate consumer on microbial communities and ecosystem functions
Published 2025-01-01“…In freshwater microcosms, we quantified variation in microbial communities and ecosystem functions and compared effects of MP concentration (0, 1000, 50000 particles/kgsediment), shape (sphere, fragment, fibre), and polymer (polyethylene, polyethylene terephthalate, polypropylene, polystyrene) with those of a model invertebrate consumer (Chironomus riparius). …”
Get full text
Article -
1493
-
1494
pH-Dependent preferential adsorption and stability of humic substances on goethite: The dual role of aromatic and aliphatic moieties
Published 2025-02-01“…These particles enriched in aromatic moieties and carboxylic groups (-COOH), which enhanced the stability of HS by facilitating the formation of inner-sphere complexes. Conversely, at pH levels exceeding 9.2, large particles (> 50 kDa) and those rich in aliphatic moieties were preferentially adsorbed for both HA and FA, attributed to the increased significance of hydrophobic interactions. …”
Get full text
Article -
1495
REGIONAL FACTORS OF MECHANISMS TRANSFORMATION FOR STRENGTHENING THE ECONOMIC SECURITY OF ENTREPRENEURIAL ACTIVITY IN THE INDUSTRIAL SECTOR OF UKRAINE
Published 2024-12-01“…It is evident that the most promising industrial sectors for enhancing the economic security of entrepreneurial activity at the regional level are energy, agri-food, extraction of critical minerals, processing industry, and IT sphere. It is important to note that these sectors are set to develop in parallel with the support for entrepreneurial initiatives and the implementation of the "green transition" in industry. …”
Get full text
Article -
1496
Le corps féminin à Casablanca : un reflet mouvant des rôles de genre ?
Published 2024-12-01“…Fulfilling male demands regarding sexuality evokes a traditional erotic image; however, the public sphere demands a toning down of this image to adhere to social norms. …”
Get full text
Article -
1497
"Russiana gloriatur ecclesia" and the issue of St. Bruno's of Querfurt missions
Published 2009-12-01“…Rex russorum, mentioned in the same hagiography, might have meant not the "Russian" king, who lived in Lithuania, and who allegedly belonged to the sphere of Kiev Russian geopolitical influence, but the leader of the tribe, who lived in Lithuania, turned into such "king" due to a more familiar name of Russia. …”
Get full text
Article -
1498
Advertising in Lithuanian Periodicals in 1918-1940: Characteristics of its Quantitative and Qualitative Developement
Published 2007-12-01“…Large manufacturers who published adverts in periodicals were wholesalers from abroad; the local market mostly offered the press or the sphere of services. Advertising of warehouses, shops, and goods contained therein rather than that of separate trademarks or brand products was much more common. 2) 1921-1926 - it did not take long for advertising to come to life again following economic and political disturbances. …”
Get full text
Article -
1499
Luminescence Nanothermometry Based on Pr3+ : LaF3 Single Core and Pr3+ : LaF3/LaF3 Core/Shell Nanoparticles
Published 2019-01-01“…Core Pr3+ : LaF3 (CPr = 1%) plate-like nanoparticles (nanoplates), core/shell Pr3+ : LaF3 (CPr = 1%)/LaF3 nanoplates, core Pr3+ : LaF3 (CPr = 1%) sphere-like nanoparticles (nanospheres), and core/shell Pr3+ : LaF3 (CPr = 1%)/LaF3 nanospheres were synthesized via the coprecipitation method of synthesis. …”
Get full text
Article -
1500
MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo
Published 2019-01-01“…Herein, we use a genetically engineered mouse model of pancreatic cancer and primary pancreatic cancer cells were derived from this model to demonstrate that small-molecule MEK inhibitors functionally abrogate cancer stem cell populations as demonstrated by reduced sphere and organoid formation capacity. Furthermore, we demonstrate that MEK inhibition suppresses TGFβ-induced epithelial-to-mesenchymal transition and migration in vitro and ultimately results in a highly significant reduction in circulating tumor cells in mice.…”
Get full text
Article