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13101
Research note: The critical role of the interaction between Eimeria tenella invasion protein RON2 and host receptor annexin A2 in mediating parasite invasion
Published 2025-02-01“…However, the mechanism by which Eimeria species invade host cells remains unclear. Previous studies have identified rhoptry neck protein 2 (RON2) from Eimeria tenella as a critical factor in host cell invasion, but a comprehensive understanding of the role of EtRON2 in host cell invasion and its relationship with E. tenella invasion is lacking. …”
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13102
<i>Vismia guianensis</i> Improves Survival of <i>Tenebrio molitor</i> and Mice During Lethal Infection with <i>Candida albicans</i>
Published 2025-01-01“…<b>Background/Objectives</b>: <i>Vismia guianensis</i> is a vegetal species popularly used to treat fungal infections. …”
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13103
Exploring the physiological and biochemical mechanisms underlying growth rate variability in Hong Kong oyster (Crassostrea hongkongensis)
Published 2025-03-01“…The Hong Kong oyster (Crassostrea hongkongensis), a key aquaculture species in southern China, has significant potential for enhancing profitability through increased growth rate. …”
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13104
piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1
Published 2025-01-01“…The resultant TSFM loss reduced mitochondrial complex I activity and mitochondrial OXPHOS, leading to mitochondrial dysfunction in OC cells, increased reactive oxygen species levels, and thus, DNA damage and apoptosis in OC cells, thereby inhibiting OC progression. …”
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13105
Stable Isotope Turnover and Fractionation of Different Feed in the Juvenile Scylla paramamosain
Published 2025-02-01“…Since the large range of fractionation factors for stable isotopes in bait materials among consumers in nearshore and estuarine ecosystems, caution should be exercised when citing fractionation factors in related ecological studies, and actual measurements or data from identical or similar species under similar environmental conditions should be used whenever possible. …”
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13106
Basic Molecular Biology, Metabolic and Immunological Mechanisms of Fecal Microbiota Transplantation
Published 2024-12-01“…According to results of 16S rRNA sequencing, the species-specific diversity of fecal microbiota increased significantly, along with decreased relative contents of opportunistic bacteria (Klebsiella, Enterococcus, Streptococcus genera). …”
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13107
Radiosensitizing capacity of fenofibrate in glioblastoma cells depends on lipid metabolism
Published 2025-02-01“…Interestingly, FF (50 μM) significantly radiosensitizes U87 cells by inducing DNA double-strand breaks through oxidative stress and impairing mitochondrial membrane integrity, but radioprotects LN18 cells by reducing the production of reactive oxygen species (ROS) and stabilizing the mitochondrial membrane potential. …”
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13108
E. Coli cytotoxic necrotizing factor-1 promotes colorectal carcinogenesis by causing oxidative stress, DNA damage and intestinal permeability alteration
Published 2025-01-01“…Results CNF1 induces the release of reactive oxidizing species and chromosomal instability in non-neoplastic intestinal epithelial cells. …”
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13109
Flavor Quality of Scomberomorus niphonius
Published 2025-02-01“…In addition, seafood contains essential nutritional lipids, including phospholipids, triglycerides, and essential fatty acids, which is an important feature distinguishing it from other species. In addition, most of the volatile flavor compounds in meat are produced by the Melad reaction and the thermal degradation of lipids (oxidation) and thiamine. …”
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13110
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
Published 2025-01-01“…Abstract Reactive oxygen species exacerbate nonalcoholic steatohepatitis (NASH) by oxidizing macromolecules; yet how they promote NASH remains poorly understood. …”
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13111
Study on the protective effect of mitochonic acid-5 on septic acute kidney injury and the underlying mechanism
Published 2025-01-01“…方法细胞实验:将肾小管细胞分为正常组、MA-5(10 µmol/L)组、LPS(10 mg/L)刺激组和LPS+MA-5治疗组,通过细胞计数试剂盒8法评估细胞活力、流式细胞术评估细胞凋亡率;活性氧(reactive oxygen species,ROS)检测试剂盒检测ROS含量;三磷酸腺苷(adenosine triphosphate,ATP)检测试剂盒检测ATP水平;蛋白质印迹法(western blot,Wb)检测沉默信息调节因子3(silence information regulator 3,SIRT3)蛋白、线粒体动力学相关蛋白[动力相关蛋白1(dynamin-related protein 1,DRP1)、视神经萎缩因子1(optic atrophy 1,OPA1)]和细胞凋亡相关蛋白[B细胞淋巴瘤2(B-cell lymphoma-2,Bcl-2)、Bcl-2相关X蛋白(Bcl-2 associated X protein,Bax)]的表达水平。…”
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13112
Effects of Density Stress on Growth and Physiology of Epinephelus fuscoguttatus ♀×Epinephelus lanceolatus ♂
Published 2025-02-01“…The pearl gentian grouper (Epinephelus fuscoguttatus ♀×Epinephelus lanceolatus ♂) is the main cultured species of marine fish in factory recirculating aquaculture system (RAS). …”
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13113
First Detection of <i>Alphacoronavirus</i> in Bats from the World’s Largest Wetland, the Pantanal, Brazil
Published 2025-01-01“…They represent 40% of the total number of mammal species in the Pantanal, a biodiversity hotspot in South America. …”
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13114
Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
Published 2025-02-01“…Mechanistic studies indicated that QCT and Mn2+ exhibited excellent peroxidase-like (POD-like) activity, catalysing the conversion of endogenous hydrogen peroxide into highly toxic hydroxyl radicals through a Fenton-like reaction, depleting glutathione (GSH), promoting reactive oxygen species (ROS) generation in mitochondria and endoplasmic reticulum, and inducing ferroptosis. …”
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13115
Contribution à l’histoire de la boulangerie romaine : étude de « pains/galettes » découverts en Gaule
Published 2021-12-01“…The major shift from hulled towards free-threshing cereals was motivated more by technical constraints weighing on the product intended for sale, than by new dietary habits: free-threshing wheat species could be directly processed. The demand for “ready-to-use” grains has sometimes been coupled with a demand for semi-processed ingredients: in Northern Gaul, we know of certain sites from the late La Tène period documenting milling activities largely exceeding the needs of their occupants, probably partly oriented towards the supply of ground or crushed products. …”
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13116
Soil smoldering in temperate forests: a neglected contributor to fire carbon emissions revealed by atmospheric mixing ratios
Published 2025-01-01“…This type of combustion was associated with specific fire characteristics, such as long-lasting thermal fire signals, and affected ecosystems encompassing needle leaf species, peatlands, and superficial lignite deposits in the soils. …”
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13117
Post sleeve gastrectomy-enriched gut commensal Clostridia promotes secondary bile acid increase and weight loss
Published 2025-12-01“…We performed shotgun metagenomic sequencing in obese subjects before and longitudinally after sleeve gastrectomy (SG), and found a significant enrichment in microbial species in Clostridia and bile acid metabolizing genes after SG treatment. …”
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13118
Rewilding beech-dominated temperate forest ecosystems: effects on carbon stocks and biodiversity indicators
Published 2025-02-01“…We emphasise that forest heterogeneity, encompassing factors such as tree age and diameter, canopy layer, species composition, and growth patterns, are important for enabling managed forests to reach peak carbon storage capacity. …”
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13119
New Horizons In The Treatment Of Metastatic Castrate Resistant Prostate Cancer
Published 2023-06-01“…-trained anatomists are now an almost extinct species in the country adding to the multitude of challenges already faced in anatomy teaching. …”
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13120
Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials
Published 2024-03-01“…Abstract Ebola virus disease (EVD) is a filoviral infection caused by virus species of the Ebolavirus genus including Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV). …”
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