Sonic hedgehog restrains the ubiquitin-dependent degradation of SP1 to inhibit neuronal/glial senescence associated phenotypes in chemotherapy-induced peripheral neuropathy via the... by Ying Zou, Shu Wu, Qian Hu, Haoxian Zhou, Yuanlong Ge, Zhenyu Ju, Shengkang Luo

“…To assess cellular senescence, we performed a senescence-associated β-galactosidase (SA-β-gal) assay, measured reactive oxygen species (ROS) levels, and examined the expression of P16, P21, and γH2AX. …”
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Effects of nitrogen fertilizer basal-to-top-dressing ratios on maize straw decomposition, soil carbon and nitrogen, and bacterial community structure in different soil textures on... by Jingyu Li, Jingyu Li, Xiaonan Yang, Rui Hou, Yujie Ma, Yanqun Wang, Yang Ma, Wenchao Zhen, Yuanyuan Huang, Xin Fu, Zhengping Peng, Zhengping Peng, Mingxin Men

“…Both soil textures had the same dominant bacterial phyla, but species abundance differed significantly. Loam had a significantly higher relative abundance of Proteobacteria and lower relative abundances of Gemmatimonadetes, Actinobacteria, and Chloroflexi than clay loam. …”
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Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway by Yihan Lai, Yihan Lai, Mingkang Li, Mingkang Li, Juan Zhan, Juan Zhan, Lin Jiang, Lin Jiang, Yuan Wu, Zhiyi Fang, Jianhan Zhou, Jianhan Zhou, Yujie Ma, Yisen Shao, Yisen Shao, Wei Wang, Wei Wang

“…At the same time, the expression of oxidative phosphorylation markers increased, the expression of glycolytic markers decreased, and glycolysis-mediated decomposition of reactive oxygen species decreased, and H2O2 and oxygen levels decreased.In addition, when MTFR2 expression increased or decreased, SOD2/H2O2 expression also increased or decreased.DiscussionIn this study, we concluded through in vitro and in vivo experiments that BJO may affect the SOD2/H2O2 signaling pathway by down-regulating MTFR2-mediated aerobic glycolysis, thereby inhibiting cell proliferation, Migration, and Invasion. …”
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Identification of serotype O3b and high-risk clone ST37 of Klebsiella pneumoniae revealed by comparative genomic analysis by Sivaraman Gopalan Krishnan, Sudha Sajeev, Visnuvinayagam Sivam, Raja Swaminathan T., Rakshit Ojha, Bibek Ranjan Shome, Mark Holmes, Thanigaivel Sundaram, Ramesh M. D., Saranya Vinayagam, Suseela Meesala, Tabarak Malik, Tabarak Malik, Pavan Kumar Dara

“…Moreover, K. pneumoniae has several species complexes (KpSC) and is very difficult to differentiate using routine microbiological methods. …”
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Injectable Autocatalytic Hydrogel Triggers Pyroptosis to Stimulate Anticancer Immune Response for Preventing Postoperative Tumor Recurrence by Zhiping Rao, Yutong Zhu, Zhuang Chen, Yi Luo, Zuo Yang, Weijing Liu, Chaoqiang Qiao, Yuqiong Xia, Peng Yang, Dong‐Man Ye, Zhongliang Wang

“…Following injection of the CP@Gel, the sustained release of CP leads to the autocatalytic generation of reactive oxygen species, resulting in caspase‐3 activation, and the pre‐administered DAC inhibits the methylation of Gsdme to elevate the GSDME protein levels, leading to intense pyroptosis and anti‐tumor immune responses. …”
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ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2 by Dan Li, Wenjie Zhang, Ruiheng Wang, Shufeng Xie, Yixin Wang, Wanxin Guo, Zixuan Huang, Chaoqun Lu, Liang Shan, Han Liu, Lifang Ma, Xumin Hou, Zhenshu Xu, Jiayi Wang

“…Ferroptosis indicators, including levels of reactive oxygen species, were used to detect the combined effect of CAR-T cells and ferroptosis-inducing drugs. …”
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Isolation and Characterization of Indigenous <i>Acetobacter</i> Strains from Cashew Apple and Their Potential Use in Vinegar Production by Yaya Anianhou Ouattara, Doudjo Soro, Kouakou Romain Fossou, Ahou Cinthia Ines Yebouet, Ismael Abraham Cissé, Dogbo Marius Akissi, Adolphe Zézé, Emmanuel Assidjo, Kouassi Benjamin Yao

“…Phenotypic and phylogenetic analysis revealed that four of them, namely OYA2, OYA6, OYA9, and OYA10, belong to the <i>A. tropicalis</i>/<i>A. senegalensis</i> species complex with 99.7% or 100% similarity. The fifth strain, OYA7, being similar (99.7%) to <i>A. syzygii</i>. …”
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Comparative evaluation of sensititre YeastOne and VITEK2 antifungal susceptibility tests with CLSI broth microdilution method of clinical Cryptococcus isolates in Taiwan by Tzu-Ping Weng, Shin-Wei Wang, Shih-Ting Lo, Shu-Li Su, Ming-I Hsieh, Pei-Jane Tsai, Pei-Fang Tsai, Chi-Jung Wu, Nan-Yao Lee, Wen-Chien Ko, Po-Lin Chen

“…However, the updated Sensititre YeastOne (SYO) version YO10C excluded Cryptococcus species for susceptibility testing. Uncorrelation of antifungal susceptibility patterns by SYO and therapeutic outcomes had been recently reported. …”
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The chiisanoside derivatives present in the leaves of Acanthopanax sessiliflorus activate autophagy through the LRP6/GSK3β axis and thereafter inhibit oxidative stress, thereby cou... by Wenxin Zhang, Wenxin Zhang, Hongbo Teng, Hongbo Teng, Tianyi Zhao, Tianyi Zhao, Roberts I. Eglitis, Xv Wang, Xv Wang, Zhengxuan Yu, Shurong Qu, Shurong Qu, Haijing Wang, Haijing Wang, Yaru Zhao, Yaru Zhao, Bowen Fan, Bowen Fan, Shuangli Liu, Shuangli Liu, Yan Zhao, Yan Zhao

“…Compound 19 treatment increased autophagy levels, thereby alleviating mitochondrial dysfunction and reducing the accumulation of reactive oxygen species (ROS).In-depth studies have found that the autophagy inhibitor 3-methyladenine (3-MA) weakens the regulatory effect of compound 19 on autophagy and inhibits the clearance of damaged cells, resulting in oxidative stress damage, apoptosis and necrosis. …”
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Characterization of Shigella flexneri serotype 6 strains from geographically diverse low- and middle-income countries by Caitlin E. Gabor, Charlotte E. Chong, Jose M. Lemme-Dumit, Tracy H. Hazen, Kate S. Baker, Karen L. Kotloff, Irene N. Kasumba, Sharon M. Tennant, Henry Badji, M. Jahangir Hossain, Richard Omore, Benjamin Ochieng, Alex O. Awuor, Billy Ogwel, Jane Juma, Eileen M. Barry, David A. Rasko

“…Comparisons of S. flexneri species level antibiotic susceptibility highlighted that clinical Sf6 isolates from Africa in the Global Enteric Multicenter Study (GEMS) and Vaccine Impact on Diarrhea in Africa (VIDA) study demonstrated geographic, serotype-specific susceptibility pattern. …”
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Comparative Study of the Chemical Composition Disparities Between Fast-twitch and Slow-twitch Muscles in Marine Teleost Fishes by Huan WANG, Shufang LIU

“…Potassium was identified as the most abundant constant element, magnesium exhibited minimal content fluctuation across diverse species, and calcium was the most abundant metallic element. …”
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Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere by R. Jin, W. Hu, W. Hu, P. Duan, M. Sheng, D. Liu, Z. Huang, M. Niu, L. Wu, J. Deng, P. Fu, P. Fu

“…Here, we cultured typical bacterial and fungal species isolated from the urban atmosphere using tryptic soy broth (TSB) and Sabouraud dextrose broth (SDB), respectively, and investigated their exometabolites to elucidate their potential roles in biogeochemical cycles. …”
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The novel H10N3 avian influenza virus acquired airborne transmission among chickens: an increasing threat to public health by Xiaoquan Wang, Huiyan Yu, Yahao Ma, Pinghu Zhang, Xiyue Wang, Jianyu Liang, Xiuling Zhang, Ruyi Gao, Xiaolong Lu, Wenhao Yang, Yu Chen, Min Gu, Jiao Hu, Xiaowen Liu, Shunlin Hu, Daxin Peng, Xian Qi, Changjun Bao, Kaituo Liu, Xiufan Liu

“…These data further emphasize the growing threat to public health posed by zoonotic H10N3 subtype AIVs.IMPORTANCEExposure to poultry in live poultry markets (LPMs) is strongly associated with human infection with avian influenza viruses (AIVs), with chickens being the most common species found in these markets in China. The prevalence of AIVs in chickens, therefore, increases the risk of human infection. …”
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Stability Analysis of Dry Yield of Z. multiflora Boiss. under Drought Stress and Mycorrhizal Fungi Symbiosis by Ashraf Aghababapoor Dehkordi, Sadollah Houshmand, Shahram Mohammady

“…Zataria multiflora Boiss. is an important medicinal plant species in the Lamiaceae family, native to Iran, Pakistan, and Afghanistan. …”
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The process of nitrogen-adaptation root endophytic bacterial rather than phosphorus-adaptation fungal subcommunities construction unveiled the tomato yield improvement under long-t... by Xiaoxia Li, Xiaoxia Li, Xiaoxia Li, Muhammad Awais, Muhammad Awais, Muhammad Awais, Shuang Wang, Shuang Wang, Shuang Wang, Shuang Wang, Zhu Zhang, Zhu Zhang, Zhu Zhang, Shuning Zhao, Shuning Zhao, Shuning Zhao, Yufeng Liu, Yufeng Liu, Yufeng Liu, Zhouping Sun, Zhouping Sun, Zhouping Sun, Hongdan Fu, Hongdan Fu, Hongdan Fu, Tianlai Li, Tianlai Li, Tianlai Li

“…We employed 16S rRNA and fungal ITS region amplicon sequencing to investigate the assembly mechanisms of abundant and rare endophytic subcommunities, network correlations, core subcommunity structures, and key species that enhance crop yield. The results indicated that organic manure and phosphorus fertilizers significantly increased the rhizosphere soil nitrogen content, phosphorus content, and phosphorus availability (labile P, moderately labile P, and non-labile P). …”
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Ovarian stimulation alternatives for in vitro production of embryos in water buffaloes by Alexis Bandeo, José Luis Konrad, Natalia Vallejos, Pablo Ponce, Marina J. Sansinena, Gustavo Crudeli, Pablo Maldonado-Vargas

“…One of these limitations is the reduced number and low competence of oocytes obtained from transvaginal follicular aspiration in this species. It has been found that ovarian stimulation with follicle- stimulating hormone (FSH) before aspiration improves the technique’s efficiency, primarily due to the increased competence of the obtained oocytes. …”
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Significant role of biomass burning in heavy haze formation in Nanjing, a megacity in China: molecular-level insights from intensive PM_2.5 sampling on winter hazy days by M. Kang, M. Kang, M. Bao, M. Bao, M. Bao, W. Song, W. Song, A. Abulimiti, A. Abulimiti, C. Wu, C. Wu, F. Cao, F. Cao, S. Szidat, Y. Zhang, Y. Zhang

“…Results show that organic matter was the predominant species, followed by nitrate (NO<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M5" display="inline" overflow="scroll" dspmath="mathml"><mrow><msubsup><mi/><mn mathvariant="normal">3</mn><mo>-</mo></msubsup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="9pt" height="16pt" class="svg-formula" dspmath="mathimg" md5hash="8c72af1edd6d67ed562efcaf5163d22b"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-73-2025-ie00001.svg" width="9pt" height="16pt" src="acp-25-73-2025-ie00001.png"/></svg:svg></span></span>). …”
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Genomic insights into the specialisation and selection of the Jinding duck by H. Chen, Y. Huang, J. Xue, K. luo, H. Tang, S. Zheng, Y. Xiong, Y. Wu, J. Li, R. Xuan, R. Xiong, Y. Gong, X. Fang, L. Wang, J. Miao, J. Zhou, H. Tan, Y. Wang, L. Wu, J. Ouyang, Y. Shen, X. Yan

“…The domestication of ducks represents a pivotal evolutionary shift from the unguided propagation of wild species to deliberate human-mediated selection, culminating in distinct behavioural, morphological, and physiological traits that differentiate domesticated ducks from their wild counterparts. …”
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Selection of suitable reference lncRNAs for gene expression analysis in Osmanthus fragrans under abiotic stresses, hormone treatments, and metal ion treatments by Yingting Zhang, Yingting Zhang, Qingyu Yan, Hui Xia, Xiangling Zeng, Xiangling Zeng, Xiangling Zeng, Jie Yang, Jie Yang, Jie Yang, Xuan Cai, Xuan Cai, Xuan Cai, Zeqing Li, Zeqing Li, Hongguo Chen, Hongguo Chen, Hongguo Chen, Jingjing Zou, Jingjing Zou, Jingjing Zou

“…This study represents the first comprehensive evaluation of lncRNA RG stability in O. fragrans, significantly enhancing the accuracy and depth of lncRNA expression analyses in this species, contributing to advancements in plant stress resistance breeding and improving environmental adaptability.…”
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BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function by Zhiming Ding, Huilei Chen, Huiru Cheng, Caiyun Wu, Hongzhen Ruan, Bingjing Zhu, Ping Zhou, Zuying Xu, Huifen Xiang

“…Consequently, BPZ-exposed embryos exhibit elevated levels of reactive oxygen species, superoxide anions, and oxidative DNA damage. …”
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