Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells by Liping Mai, Guodong He, Jing Chen, Jiening Zhu, Shaoxian Chen, Xinghua Hou, Hui Yang, Mengzhen Zhang, Yueheng Wu, Qiuxiong Lin, Min Yang, Xiaohong Li

“…The production of reactive oxygen species (ROS) was detected by the fluorescent probe 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA). …”
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Experimental use of mycobacterial antigens in tuberculin skin test on water buffalo by Alessandra Martucciello, Federica Signorelli, Piera Mazzone, Francesco Grandoni, Giovanna Cappelli, Lucia Boccia, Giuseppe Parente, Monica Cagiola, Maria Beatrice Boniotti, Esterina De Carlo, Francesco Napolitano, Giorgio Galiero

“…Therefore,  ESP could be an excellent candidate for further extensive studies in the buffalo species to improve TST Sensitivity and Specificity. …”
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Reduced Glutathione Promoted Growth Performance by Improving the Jejunal Barrier, Antioxidant Function, and Altering Proteomics of Weaned Piglets by Zhimei Tian, Yiyan Cui, Miao Yu, Dun Deng, Zhenming Li, Xianyong Ma, Mingren Qu

“…Through the proteomics analysis of the jejunal mucosa using 4D-DIA, the KEGG pathway enrichment analysis showed that differentiated proteins were significantly enriched in redox homeostasis-related pathways such as glutathione metabolism, cytochrome P450, the reactive oxygen species metabolic pathway, the oxidative phosphorylation pathway, and the phosphatidylinositol 3-kinase-serine/threonine kinase pathway in GSH2 vs. …”
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Hemolymph microbiota and immune effectors’ expressions driven by geographical rearing acclimation of the aquacultured Penaeus stylirostris by Valérie Perez, Viviane Boulo, Julien De Lorgeril, Dominique Pham, Dominique Ansquer, Gwenola Plougoulen, Valentine Ballan, Jean-Sébastien Lam, Océane Romatif, Jeremy Le Luyer, Corinne Falchetto, Caline Basset, Stanley Flohr, Moana Maamaatuaiahutapu, Marc André Lafille, Christophe Lau, Denis Saulnier, Nelly Wabete, Nolwenn Callac

“…Then, understanding the microbiota, its dynamic according to the environmental conditions and its link to the immunity would help to react to potential dysbiosis of aquacultured species. While the gut microbiota is highly studied, in marine invertebrates the hemolymph microbiota is often set aside even if it remains an important actor of the hemolymph homeostasis. …”
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Genotype-environment interactions on growth and inner shell color variation in Hyriopsis cumingii cultured in different iron-level substrates by Xuefeng Lv, Zhiyan Wang, Quanzhi Bao, Changzhi Li, Tingting Lu, Yuyang Wu, Chuntong Liu, Zhiyi Bai

“…Hyriopsis cumingii is a species that naturally inhabits substrates rich in various metal elements. …”
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Identification of a new alphacoronavirus (Coronaviridae: <i>Alphacoronavirus</i>) associated with the greater horseshoe bat (<i>Rhinolophus ferrumequinum</i>) in the south of Europ... by Sergey V. Lenshin, Tatyana V. Vishnevskaya, Alexey V. Romashin, Yulia I. Bulycheva, Oleg I. Vyshemirsky, Sophya A. Solovyeva, Asya K. Gitelman, Alexey S. Pazilin, Dmitry K. Lvov, Ben Hu, Zheng-Li Shi, Sergey V. Alkhovsky

“…Presumably the Kudep virus represents a novel species within the subgenus Decacovirus of the genus Alphacoronavirus. …”
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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity by Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting

“…Increased abundance of Cerox1 cooperatively elevates complex I subunit protein abundance and enzymatic activity, decreases reactive oxygen species production, and protects against the complex I inhibitor rotenone. …”
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Path Analysis of Morphological Traits on Weight Traits of Breeding Mya japonica by Xiaoyan XU, Meirong DU, Tinghao WANG, Zengjie JIANG

“…Pathway analysis to guide selective breeding of aquatic organisms was achieved for many species using the morphological traits of body mass and soft weight; however, pathway analysis of soft body and gonad wet weights, which are not readily available, was not reported. …”
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Contaminant-degrading bacteria are super carriers of antibiotic resistance genes in municipal landfills: A metagenomics-based study by Fang-Zhou Gao, Wei-Li Jia, Bing Li, Min Zhang, Liang-Ying He, Hong Bai, You-Sheng Liu, Guang-Guo Ying

“…Klebsiella pneumoniae, Acinetobacter nosocomialis and Escherichia coli were abundant multidrug-resistant pathogenic species in raw leachate (∼10.2 % of total microbiomes), but they rarely carried contaminant-degradation genes. …”
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Impact of bariatric surgery on liver fibrosis indices among type 2 diabetes patients in a national cohort by Arsalan Seyedi, Soghra Rabizadeh, Sahar Karimpour Reyhan, Sara Hobaby, Samira Amin Afshari, Mostafa Shomalzadeh, Seyed Ali Nabipoorashrafi, Nasrin Asgari Soran, Amirhossein Yadegar, Fatemeh Mohammadi, Fatemeh Moosaei, Elahe Saffari, Sajedeh Riazi, Fatemeh Sarv, Manouchehr Nakhjavani, Abdolreza Pazouki, Alireza Esteghamati

“…Abstract Obesity is related to liver fibrosis, a condition marked by the collection of scar tissue in the liver due to the development of a profibrotic environment, which includes increased hepatocellular death and elevated reactive oxygen species production. The aim of study is to evaluate the effect of bariatric surgery on the association between liver fibrosis indices and obesity. …”
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Quality Evaluation of Fresh Cayenne Pepper for Chili Sauce from Different Origins by Jinge XU, Zhuoqi ZHENG, Pengjie HOU, Gaoxing MA, Yandi XIONG, Zhuang MA, Meng LIU, Liang ZHAO, Xiaojun LIAO

“…The peppers from different regions exhibit slight variations in quality, which make it necessary to evaluate the raw materials before sauce using species selection. This study will provide scientific guidance for the breeding and the selection of chili pepper varieties for sauce processing.…”
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Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

“…Heynh.]. Among these species, wheat is most closely related to barley, followed by rice and maize. …”
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Understanding the Molecular Mechanisms of Incomptine A in Treating Non-Hodgkin Lymphoma Associated with U-937 Cells: Bioinformatics Approaches, Part I by Fernando Calzada, Normand García-Hernández, Elihú Bautista, José Manuel Sánchez-López, Miguel Valdes, Claudia Velázquez, Elizabeth Barbosa

“…<b>Background</b>: Incomptine A (<b>IA</b>) has been reported to have cytotoxic activity in non-Hodgkin lymphoma cancer cell lines and have effects on U-937 cells, including the induction of apoptosis, the production of reactive oxygen species, and the inhibition of glycolytic enzymes. …”
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Growth performance and survival of snakehead Channa striata juvenile with different stocking density reared in recirculation system by Adang Saputra, Tatag Budiardi, Reza Samsudin, Naufal Dwi Rahmadya

“…ABSTRACT Snakehead Channa striata is a local specific fish species and has high economic value. Until now the production of snakehead still reelies on the catch of nature because cultivation of snakehead is still underdeveloped. …”
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Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity by Yaqin Yuan, Wenqing Ning, Junjie Chen, Jiquan Li, Tianqi Xue, Cuihong An, Lingling Mao, Guangzhi Zhang, Shizhong Zhou, Jiabo Ding, Xiaowen Yang, Jianqiang Ye

“…These findings demonstrate that the STPK gene mediates resistance by regulating sulfur metabolism to counteract the reactive oxygen species induced by rifampicin. Furthermore, the approaches developed in this study provide a platform for screening new resistance genes in Brucella spp., and the identified STPK or its pathway can serve as a potential target for new drug development against rifampicin-resistant Brucella spp.IMPORTANCENew rifampicin resistance gene in Brucella melitensis is identified via bioinformatics predictions and a whole-genome transposon mutant library, new mechanisms of rifampicin resistance in B. melitensis, and new function of serine/threonine protein kinase gene and its interaction proteins.…”
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Characterization of feeding damage by tea mosquito bug, Helopeltis theivora Waterhouse (Hemiptera: Miridae) on Hainan Dayezhong tea cultivar by Qi Yao, Qi Yao, Qi Yao, You-Ze Lin, You-Ze Lin, You-Ze Lin, Shuang Qin, Shuang Qin, Shuang Qin, Zhu-Feng Lin, Zhu-Feng Lin, Zhu-Feng Lin, Xun-Cong Ji, Xun-Cong Ji, Xun-Cong Ji

“…The results indicated that the morphological features of eggs, nymphs, and adults of H. theivora in the Hainan tea region were similar to those of the same species reported in other tropical tea regions. Nymphs and adults of H. theivora primarily fed on tender leaves and produced a subcircular spot within 2 to 4 minutes. …”
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The chromosome-level genome provides insights into the adaptive evolution of the visual system in Oratosquilla oratoria by Daizhen Zhang, Xiaoli Sun, Lianfu Chen, Lianyu Lin, Chijie Yin, Wenqi Yang, Jun Liu, Qiuning Liu, Huabin Zhang, Senhao Jiang, Yongxin Li, Boping Tang, Gang Wang

“…Conclusions Our study established the first chromosome-level genome for Stomatopoda species, providing a valuable genomic resource for studying the molecular mechanisms underlying the developed visual system of O. oratoria.…”
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Therapeutic potential of the neutralizing monoclonal antibody 45G3 against encephalomyocarditis virus by Yanfang Zhang, Zhiying Wang, Yaohui Fang, Qiong Zhu, Jie Fu, Sijing Hu, Jiayin Jin, Min Zhou, Xijia Liu, Danna Zhang, Shouwei Huang, Yali Deng, Lingling Xie, Shu Shen, Jing Ye, Fei Deng, Shengbo Cao

“…Abstract Encephalomyocarditis virus (EMCV), a potential zoonotic pathogen, poses significant socioeconomic and public health challenges across various host species. Although EMCV rarely triggers severe clinical symptoms in humans, its widespread prevalence and unique biological characteristics underscore the need for continuous surveillance and the development of effective therapeutics and prophylactics. …”
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Identification and expression analysis of c-type and g-type lysozymes genes after Aeromonas hydrophila infection in African catfish by Hasan Nasrullah, Yanti Inneke Nababan, Dwi Hany Yanti, Dian Hardiantho, Sri Nuryati, Muhammad Zairin Junior, Julie Ekasari, Alimuddin Alimuddin

“…Catalytic and other conserved residues were identified by multiple sequences alignment and they showed high similarity with other teleost fish species. mRNA levels of the genes were analyzed by using qPCR method and their expressions in the spleen, liver, and head kidney were rapidly modulated after Aeromonas hydrophila injection, with different patterns were observed in each organ. …”
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Field-based evidence for the prevalence of soil antibiotic resistomes under long-term antibiotic-free fertilization by Yuhao Fu, Fang Hu, Fang Wang, Min Xu, Zhongjun Jia, Wulf Amelung, Zhi Mei, Xiaozeng Han, Marko Virta, Xin Jiang, James M. Tiedje

“…However, when antibiotic-free manure and chemical fertilizer were combined, a significant increase in nutrients (such as available nitrogen and organic matter) and MGEs occurred, leading to the enrichment of soil microbial populations, especially in certain resistant species, and Rank Ⅰ and Ⅱ ARGs. Despite the influence of various factors like bacterial communities, soil properties, heavy metals, and MGEs, the MGEs had the most significant standardized effects on shaping ARGs through both direct and indirect pathways. …”
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