Genotyping-by-sequencing derived SNP markers reveal genetic diversity and population structure of Dactylis glomerata germplasm by Muhammad Tanveer Altaf, Pablo Federico Cavagnaro, Kağan Kökten, Amjad Ali, Andres Morales, Andres Morales, Muhammed Tatar, Mehmet Bedir, Muhammad Azhar Nadeem, Muhammad Aasim, Nafiz Çeliktaş, Sheikh Mansoor, Faheem Shehzad Baloch, Faheem Shehzad Baloch

“…Cluster II revealed higher GD, associated with enhanced biomass production (128 g/plant), the most important agronomic trait in forage species, supporting the notion of heterosis in breeding programs. …”
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Effects of Salt Field Waste-Generated Bio-Organic Fertilizer Application on Bacterial Community Structure in Tea Plantations Rhizosphere Soil by Chengran Yu, Liuting Zhou, Xiaoyun Huang, Xiaofeng You, Jiali Lin, Haidong Han, Xiusheng Huang

“…The results showed that the dominant bacterial species in the rhizosphere soil of tea plants were <i>Chloroflexi</i>, <i>Acidobacteriota</i>, and <i>Proteobacteria</i>. …”
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Dietary citral increase growth and health performance of shrimp Penaeus vannamei by Ricky Hadi Pratama, Julie Ekasari, Muhammad Agus Suprayudi, Ichsan Achmad Fauzi, Wiyoto Wiyoto

“… Phytoadditives have been acknowledged to have some beneficial effects on metabolic processes and health of some aquaculture species. This study aimed to evaluate the effect of dietary citral on carbohydrate utilization, growth  and health performance of vannamei shrimp P. vannamei. …”
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Survey Report Analysis on Parasitic and Microbial Quality of Laboratory Animals in Sichuan Province, 2017-2023 by LIU Lida, CHEN Bing, XIE Na, LIU Li, ZHUANG Siqi, ZOU Yixing

“…Methods Sichuan Province has 31 licensed laboratory animal production units, with the main species including mice, rats, guinea pigs, rabbits, dogs, monkeys, and pigs. …”
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First detection and molecular characterization of Jingmen tick virus with a high occurrence in Rhipicephalus (Boophilus) microplus collected from livestock in Cameroon (2024) by Paloma Kiwan, Eva Lopez, Morena Gasparine, Geraldine Piorkowski, Agathe Colmant, Achille Paguem, Stephanie Mvodo, Laurence Thirion, Xavier de Lamballerie, Remi Charrel, Alessandra Falchi

“…They consisted of five species covering three genera: R. (B.) microplus (472; 75.9%), Amblyomma variegatum (118; 19.0%), Hyalomma truncatum (13; 2.1%), Hyalomma rufipes (2; 0.3%), and other Rhipicephalus spp. (17; 2.7%). …”
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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model by Julian E. Alecu, Veronika Sigutova, Razvan-Marius Brazdis, Sandra Lörentz, Marios Evangelos Bogiongko, Anara Nursaitova, Martin Regensburger, Laurent Roybon, Kerstin M. Galler, Wolfgang Wrasidlo, Beate Winner, Iryna Prots

“…Methods Induced pluripotent stem cell (iPSC)-derived mDANs from PD patients with a monoallelic SNCA locus duplication and unaffected controls were treated with NPT100-18A. αSyn aggregation was evaluated biochemically and reactive oxygen species (ROS) levels were assessed in living mDANs using fluorescent dyes. …”
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Thioredoxin‐interacting protein (TXNIP) is a substrate of the NEDD4‐like E3 ubiquitin‐protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells by Sara Giovannini, Yanan Li, Rosalba Pecorari, Claudia Fierro, Claudia Fiorilli, Federica Corigliano, Valeria Moriconi, Ji Zhou, Anna De Antoni, Artem Smirnov, Sara Rinalducci, Anna Maria Timperio, Massimiliano Agostini, Jinping Zhang, Yufang Shi, Eleonora Candi, Gerry Melino, Francesca Bernassola

“…In an effort to elucidate the molecular basis of WWP1 oncogenic activities, we identified WWP1 as a previously unknown negative regulator of thioredoxin‐interacting protein (TXNIP)‐mediated reactive oxygen species (ROS) production in AML cells. TXNIP inhibits the disulfide reductase enzymatic activity of thioredoxin (Trx), impairing its antioxidant function and, ultimately, leading to the disruption of cellular redox homeostasis. …”
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Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections by Ryosuke Yamamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Keiichi Yamamoto, Koki Matsushita, Miho Shimamura, Akihiro Kunisawa, Korin Sakakida, Takeshi Chujo, Masataka Adachi, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masashi Mukoyama, Kazuhito Tomizawa

“…Under normal culture conditions, bacteria did not actively release most modified nucleoside species, but robustly released nucleosides, including m2A, following addition of antibiotics or immune cells. …”
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Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Further research is required to clarify the direct effects of rhGH on specific lipid species and batokines, potentially addressing metabolic disturbances linked to obesity and aging.…”
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Evidences of the Low Implication of Mosquitoes in the Transmission of Mycobacterium ulcerans, the Causative Agent of Buruli Ulcer by Rousseau Djouaka, Francis Zeukeng, Jude Daiga Bigoga, David N’golo Coulibaly, Genevieve Tchigossou, Romaric Akoton, Sylla Aboubacar, Sodjinin Jean-Eudes Tchebe, Clavella Nantcho Nguepdjo, Razack Adeoti, Innocent Djegbe, Manuele Tamo, Wilfred Fon Mbacham, Solange E. Kakou-Ngazoa, Anthony Ablordey

“…In this study, mosquito species collected in endemic villages in Benin were screened for the presence of MU. …”
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Black carp RNF115 restricts IRF3/7-mediated antiviral signaling in innate immunity by Yixuan He, Qun Wang, Lili Xiao, Hui Wu, Jun Xiao, Jun Zou, Hao Feng

“…The C-terminal RING domain of RNF115 is highly conserved among various homologous species. Immunofluorescence assays revealed the cytoplasmic and nuclear distribution of RNF115 in the presence or absence of spring viremia of carp virus (SVCV) infection. …”
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Identification of ecological security pattern in the Qinghai-Tibet Plateau by Wangping Li, Yadong Liu, Qingrun Lin, Xiaodong Wu, Junming Hao, Zhaoye Zhou, Xiuxia Zhang

“…The study highlights the vulnerability of these corridors due to their narrow dimensions, which hinder the movement of species and ecological processes. Furthermore, critical ecological zones such as ecological expansion and conservation areas cover 66.9 % of the region, while ecological protection areas occupy only 10.4 %. …”
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Production and bioactivity test of recombinant protein common carp growth hormone by Deny Sapto Chondro Utomo, . Alimuddin, Agus Oman Sudrajat, Irvan Faizal

“…This result indicated that rGH produced in E. coli BL21 possessed biological activity and it may be useful to improve growth of aquaculture species. Key words: growth hormone, recombinant protein, common carp   ABSTRAK Penelitian ini bertujuan menghasilkan protein rekombinan hormon pertumbuhan (growth hormone, GH) dari ikan mas (Cyprinus carpio) dan menguji bioaktivitasnya. …”
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Inhibition of Mitochondrial Fission Reverses Simulated Microgravity-Induced Osteoblast Dysfunction by Enhancing Mechanotransduction and Epigenetic Modification by Qiusheng Shi, Yaxin Song, Jingqi Cao, Jing Na, Zhijie Yang, Xinyuan Chen, Ziyi Wang, Yubo Fan, Lisha Zheng

“…These mitochondrial alterations are linked to elevated reactive oxygen species levels, a decrease in ΔΨm, and a metabolic shift from oxidative phosphorylation to glycolysis, resulting in decreased adenosine triphosphate production, which are all indicative of mitochondrial dysfunction. …”
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SRC enhanced cisplatin resistance in bladder cancer by reprogramming glycolysis and pentose phosphate pathway by Yuwen Gong, Dongyang Gao, Yibo Shi, Guangrui Fan, Xiaoquan Yu, Enguang Yang, Hui Cheng, Junqiang Tian, Hui Ding, Shanhui Liu, Shengjun Fu, Yan Tao, Yuan Shui, Liang Cheng, Lanlan Li, Zhiping Wang

“…SRC activates hexokinase2 which up-regulates glycolysis and especially the pentose phosphate pathway that leading to increased nucleotide synthesis and NADPH production which can neutralize reactive oxygen species (ROS) induced by cisplatin, thereby protecting bladder cancer cells from cisplatin-induced DNA damage. …”
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Evaluation of the WRF-CMAQ Model Performances on Air Quality in China with the Impacts of the Observation Nudging on Meteorology by Jiali Li, Shaocai Yu, Xue Chen, Yibo Zhang, Mengying Li, Zhen Li, Zhe Song, Weiping Liu, Pengfei Li, Min Xie, Jia Xing

“…Abstract Accurate meteorological fields are imperative for correct air quality modeling through their influence on the various chemical species in the atmosphere. In this study, the simulations from the Community Multiscale Air Quality (CMAQ) model were conducted with meteorological fields generated by the Weather Research and Forecasting (WRF) using the original and observation nudging approaches to investigate if the better model performances for PM2.5, O3, and their related precursors in China were produced from the latter. …”
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Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice by Wenhong Yang, Tao Li, Shixiang An, Rong Chen, Yuxin Zhao, Jiaxian Cui, Mingyu Zhang, Jingkun Lu, Yunpeng Tian, Lili Bao, Pengwei Zhao

“…The abundance and diversity of the intestinal microbiota were enhanced, especially the beneficial bacterial species maintaining the balance of the intestinal flora such as Bifidobacterium and Lactobacillus. …”
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Effects of Microbial Fertilizer Application on Soil Ecology in Saline–Alkali Fields by Xingguo Tian, Xiu Zhang, Guoping Yang, Yu Wang, Qianru Liu, Jingjing Song

“…Alpha diversity analysis demonstrated that the Ace, Chao1, and Sobs indices for both bacteria and fungi were significantly higher at NS3 than before sowing, indicating the highest species richness at this stage. The Shannon index exhibited an ascending trend, and the difference in the Simpson index was not significant. …”
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Tritordeum, barley landraces and ear photosynthesis are key players in cereal resilience under future extreme drought conditions by Ander Yoldi-Achalandabaso, Aitor Agirresarobe, Artūrs Katamadze, Giulia Burini, Omar Vergara-Díaz, Mariana Mota, Cristina Oliveira, Usue Pérez-López, Rubén Vicente

“…., landraces) or ii) developing novel species (e.g., crop hybrids). Our study aimed to identify key functional traits and stress-tolerant germplasm to contribute to designing drought-resilient crops under future Mediterranean climatic conditions. …”
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Antimicrobial peptide Hs02 with rapid bactericidal, anti-biofilm, and anti-inflammatory activity against carbapenem-resistant Klebsiella pneumoniae and Escherichia coli by Deyi Zhao, Miran Tang, Panjie Hu, Xiaowei Hu, Weijun Chen, Zhexiao Ma, Huanchang Chen, Haifeng Liu, Jianming Cao, Tieli Zhou

“…Further mechanistic studies demonstrated that Hs02 specifically targeted and bound to bacterial outer membrane lipopolysaccharides (LPS), disrupted membrane permeability and integrity, which led to intracellular reactive oxygen species (ROS) accumulation. Furthermore, Hs02 neutralized LPS, thereby suppressing the production of pro-inflammatory cytokines TNF-α, IL-6, and IL-1β in murine macrophage RAW 264.7 cells. …”
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