A Blueprint for the Problem Formulation Phase of EPA-Type Ecological Risk Assessments for 316(b) Determinations by Webster Van Winkle, William P. Dey, Steve M. Jinks, Mark S. Bevlhimer, Charles C. Coutant

“…Regardless of how the generic analysis plan is modified to develop a facility-specific analysis plan, the resulting plan should be viewed as a tool for comparing representative species and alternative CWIS options by focusing on relative changes (i.e., proportional or percent changes) in various measures. …”
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A gut-derived Streptococcus salivarius produces the novel nisin variant designated nisin G and inhibits Fusobacterium nucleatum in a model of the human distal colon microbiome by Garreth W. Lawrence, Enriqueta Garcia-Gutierrez, A. Kate O’Mahony, Calum J. Walsh, Paula M. O'Connor, Máire Begley, Caitriona M. Guinane, Paul D. Cotter

“…Here, we describe this nisin variant produced by S. salivarius, a species that is frequently a focus for probiotic development. …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…Administration of YNJ-containing mouse serum increased cell viability and decreased malondialdehyde and reactive oxidative species contents in LPS-stimulated MLE-12 cells. YNJ-containing serum also decreased the secretion of tumor necrosis factor-α, IL-6, and IL-1β in LPS-stimulated RAW264.7 macrophages, and promoted macrophage polarization toward an M2 phenotype. …”
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Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation by Ruixin Li, Xiaochen Jia, Hongguo Xie, Xueran Wang, Jinxuan Wen, Guanglu Yu, Chunlai Zhang, Yeqing Sun, Heng Yin

“…In this study, we developed a novel intelligent response‐controlled release nano‐pesticide, Vali@mPEG‐TK‐COS, by coupling chitosan oligosaccharide (COS), a plant immunity regulator, and methoxy polyethylene glycols (mPEG) at either end of thioketal (TK), a material responsive to reactive oxygen species (ROS), and incorporating validamycin (Vali) for controlled release. …”
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Safety of vancomycin-loaded cement spacers for treating gram-positive periprosthetic joint infections in two-stage resection arthroplasty among patients with renal insufficiency by Yu-Chih Lin, Chih-Hsiang Chang, Chih-Chien Hu, Yung-Chieh Liang, Pang-Hsin Hsieh, Sheng-Hsun Lee, Sheng-Hsuan Lin

“…The infection-free interval, aseptic revision rates, and bacterial profiles specific to gram-positive species showed no significant differences between the groups. …”
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<i>Cannabis sativa</i> L. Extract Increases COX-1, COX-2 and TNF-α in the Hippocampus of Rats with Neuropathic Pain by Joanna Bartkowiak-Wieczorek, Małgorzata Jamka, Radosław Kujawski, Marcin Hołysz, Agnieszka Bienert, Kamila Czora-Poczwardowska, Michał Szulc, Przemysław Mikołajczak, Anna Bogacz, Anna-Maria Wizner, Karolina Wielgus, Ryszard Słomski, Edyta Mądry

“…The increased expression of COX-1, COX-2, and TNF-α (in comparison to groups receiving NaCl, vincristine, and gabapentin) in the rat hippocampus and COX-1 in the cerebral cortex suggests that <i>Cannabis</i> may have a pro-inflammatory effect. Due to species specificity, the results of our research based on rats require confirmation in humans. …”
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Responses of Phospholipase D and Antioxidant System to Mechanical Wounding in Postharvest Banana Fruits by Li Li, Xuemei He, Jian Sun, Changbao Li, Dongning Ling, Jinfeng Sheng, Fengjin Zheng, Guoming Liu, Jiemin Li, Yayuan Tang, Ping Yi, Ming Xin, Zhichun Li, Zhugui Zhou

“…The concentrations of reactive oxygen species (ROS) such as superoxide anion (O2•-) and hydrogen peroxide (H2O2) in fruits increased under mechanical wounding. …”
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Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis by Jing Ni, Lirong Ren, Ying Liang, Ying Ma, Hejian Xiong

“…However, their effects on the metabolome of aquatic species have not yet been identified. This study evaluated the in vitro effects of our previous synthesized SeNPs, coated with abalone visceral polysaccharide-protein complexes (PSP-SeNPs), on the proliferation of probiotics and common aquatic pathogens, and the in vivo effects on the gut microbiome and metabolome of tilapia. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

“…Antimicrobial photodynamic therapy (APDT) is based on using of photosensitizers (PS), which generate reactive oxygen species when exposed to visible or infrared light. …”
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Serological, phenotypic and molecular characterization of brucellosis in small ruminants in northern Algeria by Ibrahim Nabi, Rachid Achek, Rachid Achek, Abdelkadir Karim, Falk Melzer, Hanka Brangsch, Mandy C. Elschner, Heinrich Neubauer, Hosny El-Adawy, Hosny El-Adawy

“…Whole genome sequencing (WGS) was used for genomic analysis of isolated Brucella species. The results of this study showed that anti-Brucella antibodies were detected in 46 (83.6%) and 52 (54.2%) milk and serum samples, respectively. …”
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Effects of different water and fertilizer treatments on the matrix properties and plant growth of tailings waste by Yanchen Li, Yang Yang, Jialin He, Shan Guo, Xuejing An, Yan Li, Rui Guo, Yipeng Lin, Ruipeng Zhang

“…Additionally, TK exhibited a positive correlation with the growth status of all five plant species. Moreover, the water and fertilizer substrate displayed a positive association with the growth status of Pennisetum alopecuroides (L.) …”
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A novel synthetic synovial fluid model for investigating biofilm formation and antibiotic susceptibility in prosthetic joint infections by Amber De Bleeckere, Frits van Charante, Thibault Debord, Stien Vandendriessche, Michiel De Cock, Marte Verstraete, Fabien Lamret, Bram Lories, Jerina Boelens, Fany Reffuveille, Hans P. Steenackers, Tom Coenye

“…The SSF2 medium allowed isolates to grow and form biofilm-like aggregates varying in size and shape between different species. For most isolates cultured in SSF2, a reduced susceptibility to the tested antibiotics was observed when compared to susceptibility data obtained in general media. …”
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Gully mitigation and rehabilitation measures have varying effects on soil macrofauna abundance and diversity in semi-arid lands by Harrison Churu, Solomon Kamau, Wilson Ng’etich, Keziah Magiroi, Bonface Alkamoi, James Mutio, Syphyline Kebeney, Fred Wamalwa

“…Thus, this study evaluated the influence of gully erosion mitigation and rehabilitation measures on soil macrofauna abundance, diversity and species richness in semi-arid lands with severe degradation and where restoration efforts are being put in place. …”
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Remote-sensing-based forest canopy height mapping: some models are useful, but might they provide us with even more insights when combined? by N. Besic, N. Picard, C. Vega, J.-D. Bontemps, L. Hertzog, J.-P. Renaud, J.-P. Renaud, F. Fogel, M. Schwartz, A. Pellissier-Tanon, G. Destouet, F. Mortier, F. Mortier, M. Planells-Rodriguez, P. Ciais

“…Moreover, we observed that the forest stand vertical structure, the dominant tree species, and the type of forest ownership systematically emerge as statistically significant factors influencing the model divergences. …”
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Population Dynamics of Bullet Tuna (Auxis rochei Risso 1881) from the Indian Ocean, West Nusa Tenggara, Indonesia by Evron Asrial, Ruly Isfatul Khasanah, Fathurriadi Fathrurriadi, Yasir Arapat, Usma Kurniawan Hadi, Lalu Achmad Tan Tilar Wangsajati Sukmaring Kalih, Lalu Samsul Rizal, Mita Ayu Liliyanti, Erwin Rosadi, Daduk Setyohadi, Muhammad Junaidi, Ishani Nelunika Rathnayake

“…. • The length at first maturity (Lm) of bullet tuna (Auxis rochei) was analyzed • The eligibility status of bullet tuna (Auxis rochei) has been analyzed and estimated • The LWR curve can be used to estimate age groups of fish compared to the sigmoid curve • The CF cannot be automatically used to estimate fish worth selling   Abstract The bullet tuna (Auxis rochei), BLT or tongkol lisong (Indonesian) is a species of neritic tuna which is one of the target fish for small scale fishers. …”
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The ontogenic study of early life stages of culture-bred Nomorhamphus sp. (Zenarchopteridae) from Lindu, Central Sulawesi by Muh Herjayanto, Odang Carman, Dinar Tri Soelistyowati, Alimuddin, Aryo Wenang Wicaksono, Harton Arfah

“…This fish is unique as an endemic species with a halfbeak-like jaw and orange color on the caudal fin. …”
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The gut–kidney axis is regulated by astragaloside IV to inhibit cyclosporine A-induced nephrotoxicity by Cong Han, Ran-ran Gao, Le Zhou, Wei Li

“…The gut microbiota, renal transcriptome, and urine metabolome were separately detected to construct a gut–transcriptome–metabolome coexpression network. The target species, target genes, and target metabolites of AS-IV were evaluated.ResultsCsA led to increased proteinuria and a deterioration of kidney function, accompanied by increased inflammation and oxidative stress, whereas AS-IV improved kidney damage. …”
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The role of manganese in CoMnOx catalysts for selective long-chain hydrocarbon production via Fischer-Tropsch synthesis by Hao Chen, Zan Lian, Xiao Zhao, Jiawei Wan, Priscilla F. Pieters, Judit Oliver-Meseguer, Ji Yang, Elzbieta Pach, Sophie Carenco, Laureline Treps, Nikos Liakakos, Yu Shan, Virginia Altoe, Ed Wong, Zengqing Zhuo, Feipeng Yang, Ji Su, Jinghua Guo, Monika Blum, Saul H. Lapidus, Adrian Hunt, Iradwikanari Waluyo, Hirohito Ogasawara, Haimei Zheng, Peidong Yang, Alexis T. Bell, Núria López, Miquel Salmeron

“…Employing TEM and in-situ X-ray spectroscopies (XRD, APXPS, and XAS), we determine the catalyst’s atomic structure, chemical state, reactive species, and their evolution under FTS conditions. …”
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Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets by Yijiang Bei, Linqiang He, Jin Jing, Xiaoming Chen, Fan Yuan, Gaohua Yao, XueYan Ding, Lei Wang, Fan Zhou

“…The Chinese hook snout carp (Opsariichthys bidens) is a newly developed economic fish species for its good taste, high nutritional content, and suitability for aquaculture in southeastern China, but its dietary protein requirement has not been investigated. …”
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Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm by Amjad Riaz, Ghulam S. Khan, Muhammad Zahid Tahir, Muhammad Yasir Zahoor, Hifz-ul-Rahman Hifz-ul-Rahman

“…Crocin is a carotenoid known for its antioxidant potential through scavenging reactive oxygen species. The current study investigated the effect of crocin addition in the semen extender on the post-thaw quality, fertility- associated gene expression, and fertilization potential of buffalo bull sperm. …”
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