Reconstruction and computer analysis of the structural and functional organization of the gene network regulating cholesterol biosynthesis in humans and the evolutionary characteri... by A. D. Mikhailova, S. A. Lashin, V. A. Ivanisenko, P. S. Demenkov, E. V. Ignatieva

“…Humans and other animal species can absorb cholesterol from food. Cholesterol is also syn­thesized de novo in the cells of many tissues. …”
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RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells by Nan Zhang, Jie Yang, Yuan Zhao, Wenhong Li, Bo Zhao, Rongxian Li, Zuoshun He, Shiyan Gu

“…Proteomic assay revealed that in passage 40 cells, 350 proteins showed differentially expressed in comparison to control, and these proteins were primarily enriched in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of “pathways in cancer” and “Chemical carcinoma-reactive oxygen species”. Moreover, the mRNAs of Nuclear factor kappa B (NF-κB) p65 and NAD(P)H: quinone oxidoreductase 1 (NQO1), the key signaling molecules in these two signaling pathways, were predicted to contain m6A modification sites with high confidence. …”
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Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (<i>Z</i>)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5<i>H</i>)-one Analogs: In Vitro and In Vivo Insight... by Hee Jin Jung, Hye Jin Kim, Hyeon Seo Park, Hye Soo Park, Jeongin Ko, Dahye Yoon, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon

“…Compounds <b>8</b> and <b>10</b> exhibited strong antioxidant capacities, scavenging 2,2-diphenyl-1-picrylhydrazyl, (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid)⁺ radicals, and reactive oxygen species. Hybrid compounds <b>10</b> and <b>15</b> are potential therapeutic agents for skin hyperpigmentation disorders.…”
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Landscape connectivity alters the evolution of density-dependent dispersal during pushed range expansions by Dahirel, Maxime, Bertin, Aline, Calcagno, Vincent, Duraj, Camille, Fellous, Simon, Groussier, Géraldine, Lombaert, Eric, Mailleret, Ludovic, Marchand, Anaël, Vercken, Elodie

“…As human influence reshapes communities worldwide, many species expand or shift their ranges as a result, with extensive consequences across levels of biological organization. …”
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Structural characterization and anti-inflammatory activities of novel polysaccharides obtained from Pleurotus eryngii by Han Wang, Sai Ma, Alfred Mugambi Mariga, Qiuhui Hu, Qian Xu, Anxiang Su, Ning Ma, Gaoxing Ma

“…Natural polysaccharides named PEP-0.1-1, PEP-0-1 and PEP-0-2 from edible mushroom species Pleurotus eryngii were obtained in the present study. …”
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Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells by Qi Zhao, Qi Zhao, Qi Zhao, Yan Zhang, Yan Zhang, Jieyu Liu, Peipei Chen, Annabeth Onga, Namki Cho, Ri Cui, Chenguo Zheng

“…Consequently, the search for anti-cancer components with high efficacy and low cytotoxicity has become a significant focus in recent years.MethodsThe anti-tumor effects of PD, OXA or their combination were assessed by cell viability, colony formation, and wound-healing assays. Reactive oxygen species (ROS) generation was measured by flow cytometry and DNA damage was assessed by immunofluorescence assay. …”
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Typologie et caractéristiques des pâturages de la commune urbaine de Téra dans l'ouest du Niger by Hamza Seydou Korombé, Idrissa Soumana, Abdoul Aziz Maman Lawal, Ibrahim Djibo, Sanoussi Atta

“…Les espèces caractéristiques des pâturages ont été identifiées à travers l’Indicator Species Analysis (ISA) avec le logiciel PCORD 5. Les différences entre les pâturages et l’homogénéité de la flore au sein de chaque pâturage ont été analysées. …”
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Apportioning and Locating PM2.5 Sources Affecting Coastal Cities: Ulsan in South Korea and Dalian in China by Eunhwa Choi, Kwonho Jeon, Young Su Lee, Jongbae Heo, Ilhan Ryoo, Taeyeon Kim, Chuanlong Zhou, Philip K. Hopke, Seung-Muk Yi

“…Abstract PM2.5 mass and its constituent species were analyzed in two coastal cities (Ulsan, South Korea, and Dalian, China) between July 13, 2018, and September 20, 2019. …”
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Effects of different microplastics on the physicochemical properties and microbial diversity of rice rhizosphere soil by Sheng Lai, Sheng Lai, Sheng Lai, Cunzhong Fan, Ping Yang, Ping Yang, Yuanyuan Fang, Yuanyuan Fang, Lanting Zhang, Lanting Zhang, Minfei Jian, Guofei Dai, Guofei Dai, Jutao Liu, Jutao Liu, Huilin Yang, Liqin Shen, Liqin Shen

“…Furthermore, microplastics reduced the soil bacterial diversity index and altered the community structure of dominant bacterial species, with DOC content and FDA hydrolase being the main factors influencing the soil bacterial community. …”
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Analysis of the CHS Gene Family Reveals Its Functional Responses to Hormones, Salinity, and Drought Stress in Moso Bamboo (<i>Phyllostachys edulis</i>) by Shiying Su, Xueyun Xuan, Jiaqi Tan, Zhen Yu, Yang Jiao, Zhijun Zhang, Muthusamy Ramakrishnan

“…However, its molecular functions remain largely unknown in <i>Phyllostachys edulis</i>, which is one of the most economically and ecologically important bamboo species and the most widely distributed one in China. …”
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Whole-genome sequencing and secondary metabolite exploration of the novel Bacillus velezensis BN with broad-spectrum antagonistic activity against fungal plant pathogens by Yanli Zheng, Tongshu Liu, Ziyu Wang, Xu Wang, Haiyan Wang, Ying Li, Wangshan Zheng, Shiyu Wei, Yan Leng, Jiajia Li, Yan Yang, Yang Liu, Zhaoyu Li, Qiang Wang, Qiang Wang, Yongqiang Tian

“…Identification revealed that this strain belongs to the species Bacillus velezensis and exhibits significant inhibitory effects against various fungal plant pathogens. …”
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Identification of Salvia miltiorrhiza germplasm resources based on metabolomics and DNA barcoding by Gaojie He, Jinhui Man, Ying Chen, Xiaoqin Zhang, Xin Wang, Kelu An, Laha Amu, Wenqin Chen, Baowei Wang, Yue Shi, Yue Shi, Xiaohui Wang, Xiaohui Wang, Shengli Wei, Shengli Wei

“…Chloroplast genome was used to distinguish intra-genus species and DNA barcoding was used to identify germplasm sources.ResultsThe fingerprinting analysis proved that there is no chemical composition consistency between S. miltiorrhiza radix and its adulterants. …”
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Trade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostase... by Min Zhou, Yuting Wu, Yuchen Yang, Yan Yuan, Junnan Lin, Long Lin, Zhou Li

“…These organic metabolites helped to maintain osmotic adjustment, energy supply, reactive oxygen species homeostasis, and cellular metabolic homeostasis with regard to salt stress. …”
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Dietary supplementation with Epimedium contributes to the improvement of hormone levels, gut microbiota, and serum metabolite composition in the Chinese forest musk deer (Moschus b... by Shan Xie, Shan Xie, Qinlin Yang, Zaixiang Ying, Zaixiang Ying, Mingcheng Cai, Wenqiao Fan, Hanyu Gao, Hanyu Gao, Xiaolan Feng, Yongjiang Wu

“…It is listed as a National Level I key protected species in China. However, these animals are prone to stress responses in captive environments. …”
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Serum metabolic profiles in quails: Effects of age, breed, and sex by Qin He, Hanle Shang, Yizhong Huang, Lizhi Li, Zhuomin Wu, Huihui Ran, Jiguo Xu, Xinwei Xiong

“…Over the past decade, metabolomic research in livestock and poultry has gained considerable momentum; however, quail metabolomics still lags behind that of livestock species such as chickens, pigs, and cattle. Quails are important models due to their low-cost protein sources—both eggs and meat—and practical benefits such as minimal space requirements, high egg production, disease resistance, and rapid reproduction. …”
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Solar Modulation of Low-energy Cosmic-Ray Nitrogen and Its Comparison with Oxygen by Yun Li, Xiaoping Zhang, Shuai Fu, Zhenning Shen, Yi Xu, Haoyu Lu, Jinbin Cao, Tianle Zhu

“…Further model results indicate that GCR nitrogen and oxygen undergo comparable modulation processes within the heliosphere and the slight difference between the observed power-law indices of nitrogen and oxygen spectrum is due to the distinct local interstellar spectrum of the two species. Besides, an analysis is made to explain the observed more flattened ACR spectrum of nitrogen than oxygen caused by the slightly different charge-to-mass ratio Z / A .…”
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Tigers and Their Prey in Bukit Rimbang Bukit Baling: Abundance Baseline for Effective Wildlife Reserve Management by Febri Anggriawan Widodo, Stephanus Hanny, Eko Hery Satriyo Utomo, Zulfahmi Zulfahmi, Kusdianto Kusdianto, Eka Septayuda, Tugio Tugio, Effendy Panjaitan, Leonardo Subali, Agung Suprianto, Karmila Parakkasi, Nurchalis Fadhli, Wishnu Sukmantoro, Ika Budianti, Sunarto Sunarto

“…We estimated density for tigers and calculated trap success rate (TSR; independent pictures/100 trap nights) for main prey species. Three blocks in the reserve were sampled from 2012 to 2015 accumulating a total of 8,125 effective trap nights. …”
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Modeling the tropical fish community related to land uses and environmental determinants by N. Takarina, O. Chuan, M. Afifudin, L. Tristan, I. Arif, A. Adiwibowo

“…The intact site had higher fish diversity and made a greater contribution to conservation by providing habitats for fish species with the least concern and vulnerability statuses, according to the International Union for Conservation of Nature Red List. …”
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Nutritional Properties, Antioxidant and Antihaemolytic Activities of the Dry Fruiting Bodies of Wild Edible Mushrooms Consumed by Ethnic Communities of Northeast India by Merilin Kakoti, Dibya Jyoti Hazarika, Assma Parveen, Samim Dullah, Alokesh Ghosh, Dipankar Saha, Madhumita Barooah, Robin Chandra Boro

“…In the present study, the 32 wild edible mushroom samples of 11 species collected from different parts of Northeast India were evaluated for their proximate composition, mineral and vitamin (ascorbic acid and riboflavin) contents, antioxidant and antihaemolytic activity, and profiles of organic and phenolic acids. …”
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First note of QTL mapping of low vigor traits using the updated F2 ‘Koroneiki’ linkage map of olive by Irene Granata, Aparna S. Balan, Aparna S. Balan, Claudio Di Vaio, Antonino Ioppolo, Tiziano Caruso, Silvia Fretto, Jubina Benny, Antonio Giovino, Daniel James Sargent, Francesco Paolo Marra, Annalisa Marchese

“…Although genome editing is still a future possibility due to the complexity of olive genetics and the species’ recalcitrance to transformation, our study lays a foundational understanding to guide future breeding programs. …”
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