TRPV1 Activation Attenuates High-Salt Diet-Induced Cardiac Hypertrophy and Fibrosis through PPAR-δ Upregulation by Feng Gao, Yi Liang, Xiang Wang, Zongshi Lu, Li Li, Shanjun Zhu, Daoyan Liu, Zhencheng Yan, Zhiming Zhu

“…High-salt diet-induced cardiac hypertrophy and fibrosis are associated with increased reactive oxygen species production. Transient receptor potential vanilloid type 1 (TRPV1), a specific receptor for capsaicin, exerts a protective role in cardiac remodeling that resulted from myocardial infarction, and peroxisome proliferation-activated receptors δ (PPAR-δ) play an important role in metabolic myocardium remodeling. …”
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Comprehensive agrobiological assessment and analysis of genetic relationships of promising walnut varieties of the Nikitsky Botanical Gardens by Yu. V. Plugatar, I. I. Suprun, S. Yu. Khokhlov, I. V. Stepanov, E. A. Al-Nakib

“…Furthermore, the presence of two genetically distant groups indicates the presence of two independently formed pools of the autochthonous gene pool of the species Juglans regia L. on the Crimean Peninsula…”
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Carnitine palmitoyltransferase 1C promotes EMT-associated cisplatin resistance in non-small cell lung cancer cells by Renjie Chen, Jiahui Wang, Shuoyu Huang, Xuefeng Hu, Xinran He, Tiange Zhang, Yunhan Hu, Huijun Wei, Sihui Nian, Yushu Huang, Zhihao Wu

“…Immunofluorescence staining was used to determine reactive oxygen species levels. The expression patterns of EMT markers and carnitine palmitoyltransferase 1C (CPT1C) were determined by Western blot analysis. …”
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Aggregation control of anionic pentamethine cyanine enabling excitation wavelength selective NIR-II fluorescence imaging-guided photodynamic therapy by Yibin Li, Fei Qu, Fang Wan, Cheng Zhong, Jingyi Rao, Yijing Liu, Zhen Li, Jintao Zhu, Zhong’an Li

“…Abstract Near-infrared (NIR)-II fluorescence imaging-guided photodynamic therapy (PDT) has shown great potential for precise diagnosis and treatment of tumors in deep tissues; however, its performance is severely limited by the undesired aggregation of photosensitizers and the competitive relationship between fluorescence emission and reactive oxygen species (ROS) generation. Herein, we report an example of an anionic pentamethine cyanine (C5T) photosensitizer for high-performance NIR-II fluorescence imaging-guided PDT. …”
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Molecular detection and genomic characterization of Samak Micromys paramyxovirus-1 and -2 in Micromys minutus, Republic of Korea by Augustine Natasha, Sarah E. Pye, Seung Hye Cho, Haryo Seno Pangestu, Jieun Park, Kyungmin Park, Sara P. Prayitno, Bohyeon Kim, Jong Sun Lee, Jongwoo Kim, Shailesh Budhathoki, Yeonsu Oh, Jin-Won Song, Carolina B. López, Jun Gyo Suh, Won-Keun Kim

“…The overlap in habitats between rodents and humans increases the risk of zoonotic events, underscoring the importance of active surveillance. Rodent species, such as Apodemus agrarius, are natural hosts for Paramyxoviridae in the Republic of Korea (ROK). …”
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Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes by Juraj Vozar, Nikola Hudakova, Natalia Nosalova, Mykhailo Huniadi, Dana Marcincakova, Slavomir Hornak, Lubica Hornakova, Petra Majerova, Dasa Cizkova, Dasa Cizkova

“…These natural antioxidants might help neutralize reactive oxygen species (ROS) and modulate inflammatory responses, which are often linked with chondrocyte damage in osteoarthritis. …”
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Nicotinamide Mononucleotide Restores NAD⁺ Levels to Alleviate LPS-Induced Inflammation via the TLR4/NF-κB/MAPK Signaling Pathway in Mice Granulosa Cells by Mehboob Ahmed, Umair Riaz, Haimiao Lv, Muhammad Amjad, Sohail Ahmed, Shaokat Ali, Muhammad Usman Ghani, Guohua Hua, Liguo Yang

“…NMN supplementation significantly reduced reactive oxygen species ROS and improved steroidogenesis activity by restoring the estradiol (E2) and progesterone (P4) levels in LPS-treated GCs. …”
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Segment-based Volatile Organic Compound Emission Characteristics from Different Types of Coking Plants in China by Rumei Li, Yulong Yan, Lin Peng, Yinghui Li, Zhuocheng Liu, Zhanchun Fan, Huanfeng Li, Yang Xu, Cheng Wang, Dongmei Hu, Zhiyong Li

“…The fugitive emissions were also monitored at the mechanical plant, and the most abundant species leaking from the oven were benzene, toluene, ethane, m-xylene, and ethylene, whereas those leaking from byproducts were benzene, propane, ethane, ethylene, n-pentane, n-butane, isobutene, 1-butene, toluene, and propylene. …”
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Beeswax Alcohol (BWA, Raydel^®) Improved Blood Oxidative Variables and Ameliorated Severe Damage of Zebrafish Kidneys, Testes, and Ovaries Impaired by 24-Week Consumption... by Kyung-Hyun Cho, Ashutosh Bahuguna, Ji-Eun Kim, Yunki Lee, Sang Hyuk Lee, Cheolmin Jeon, Cheol-Hee Kim

“…Also, the intake of BWA affected the morphology of HC+Gal-compromised kidney and induced histological changes by mitigating reactive oxygen species (ROS) production and cellular senescence, which was markedly more effective than the results seen in the CoQ₁₀ group. …”
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Reversible multivalent carrier redox exceeding intercalation capacity boundary by Yuanhe Sun, Rui Qi, Qi Lei, Wei Zhang, Haitao Li, Mengru Lin, Hao Shi, Jianrong Zeng, Wen Wen, Yi Gao, Xiaolong Li, Chunyi Zhi, Daming Zhu

“…Despite plausibility, this high-capacity dream is untenable with the total tolerable redox charge-transfer limit of the host material for all carrier species equally, which is historically assumed to depend on the material rather than the guest carrier itself, and the kinetic hysteresis induced by larger charge/radius ratios induced kinetic hysteresis further enlarges the divide. …”
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Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for eliminat... by Hervé Kengne Fogang, Hugues C. Nana Djeunga, Alvine C. Kengne-Fokam, Murielle C. Tchami Mbagnia, Flobert Njiokou, Dickson S. Nsagha, Emmanuel Yenshu, Joseph Kamgno

“…Of the 154 snails that survived during 30 days of follow-up, 16 (10.4 %; 95 % CI: 6.5–16.2) shed cercariae, the infection rate being quite heterogeneous between snails' species and communities. This study revealed a residual transmission of schistosomiasis in the snail populations, emphasizing the need for snail control to complement current interventions and accelerate schistosomiasis transmission interruption.…”
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Gardnerella vaginalis-binding IgA in the urethra of sexually experienced males by Rachel Liu, R. M. Galiwango, Daniel Park, Sanja Huibner, Maliha Aziz, Aggrey Anok, James Nnamutete, Yahaya Isbirye, John Bosco Wasswa, Deo Male, Godfrey Kigozi, Aaron A. R. Tobian, Jessica L. Prodger, Cindy Liu, Bryan Coburn, Rupert Kaul

“…Results Urethral antibodies binding both bacterial species were readily detectable, with G. vaginalis predominantly bound by IgA, and S. mitis equivalently by IgA and IgG. …”
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Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria by Nahed Fathallah Fahmy, Marwa Mahmoud Abdel-Kareem, Heba A. Ahmed, Mena Zarif Helmy, Ekram Abdel-Rahman Mahmoud

“…Recent studies showcase the effectiveness of various fungi species in nanoparticle synthesis. Mycosynthesized silver nanoparticles (AgNPs) and selenium nanoparticles (SeNPs) using Aspergillus carneus MAK 259 has been investigated and demonstrate antibacterial, antibiofilm and synergistic activities against (MRSA) and (MDR P. aeruginosa). …”
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Voriconazole Pharmacokinetics Administered at 4 mg/kg IM and IV in Nursehound Sharks (<i>Scyliorhinus stellaris</i>) Under Human Care by Daniela Cañizares-Cooz, Daniel García-Párraga, Sonia Rubio-Langre, Teresa Encinas, Pablo Morón-Elorza

“…The information available related to the treatment of fungal diseases in elasmobranchs is limited and is frequently based on the empirical knowledge provided by the professionals and clinicians working with these species. The use of azole antifungal drugs, especially voriconazole, has shown promise as a potential treatment option for fungal infections in elasmobranchs, with favorable outcomes in some registered cases. …”
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Effects of poultry by-product meal and complete replacement of fish oil with alternative oils on growth performance and gut health of rainbow trout (Oncorhynchus mykiss): a FEEDNET... by Imam Hasan, Simona Rimoldi, Biagina Chiofalo, Marianna Oteri, Micaela Antonini, Rosangela Armone, Violeta Kalemi, Laura Gasco, Genciana Terova

“…Abstract Background Aquaculture, traditionally a form of biotechnology, has evolved to integrate innovative biotechnological applications, such as advanced feed formulations, aimed at improving the growth performance and health of farmed fish species. In the present study, the effects of feeding rainbow trout with novel feed formulations were investigated. …”
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Comparative evaluation of various DNA extraction methods and analysis of DNA degradation levels in commercially marketed Chestnut rose juices and beverages by Yongchao Ren, Yunlong Ma, Yanqi Li, Yun Song, WeiWei Zhao, Xuncai Huang, Danmin Yu, Jian Li, Zuogang Xu, Wenjun Zhao

“…The utilization of DNA-based methods for species identification is a valuable instrument in the field of food inspection and regulation. …”
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Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagans PV989 by Lei Xu, Min Yin, Tingyuan Zhu, Yabo Liu, Yuanyuan Ying, Junwan Lu, Chaoqing Lin, Jianchao Ying, Teng Xu, Liyan Ni, Qiyu Bao, Shunfei Lu

“…Homologues of R4′ were found in other plasmids or chromosomes, suggesting that horizontal gene transfer (HGT) occurred among different bacteria of various species or genera. The acquired functional genes may play important roles in the adaptation of bacteria to different hosts or environmental conditions.…”
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Phylogenetic and Comparative Genomics Study of <i>Cephalopina titillator</i> Based on Mitochondrial Genomes by Huaibing Yao, Wanpeng Ma, Zhanqiang Su, Yuanyuan Yan, Yang Li, Weidong Cui, Jie Yang, Faqiang Zhan, Min Hou

“…The phylogenetic analysis clustered this species with the Oestrinae, showing that the subfamily did not exhibit monophyly. …”
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Development and Evaluation of Photoprotective O/W Emulsions Containing Hydroalcoholic Extract of Neoglaziovia variegata (Bromeliaceae) by Raimundo Gonçalves de Oliveira-Júnior, Grasielly Rocha Souza, Christiane Adrielly Alves Ferraz, Ana Paula de Oliveira, Camila de Souza Araújo, Sarah Raquel Gomes de Lima-Saraiva, Silvio Alan Gonçalves Bomfim Reis, Talita Mota Gonçalves, Larissa Araújo Rolim, Pedro José Rolim-Neto, Francine Celise Siqueira César, Jackson Roberto Guedes da Silva Almeida

“…Neoglaziovia variegata is a Bromeliaceae plant species widely found in Brazil with several pharmacological properties, including photoprotective activity. …”
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Anti-Inflammatory, Antioxidant and Antibacterial Properties of Tomato Skin and Pomegranate Peel Extracts: A Sustainable Approach for Oral Health Care by Alessia Silla, Angela Punzo, Francesca Bonvicini, Matteo Perillo, Marco Malaguti, Antonello Lorenzini, Ismaela Foltran, Dario Mercatante, Mara Mandrioli, Maria Teresa Rodriguez-Estrada, Silvana Hrelia, Cristiana Caliceti

“…Lastly, the antibacterial activity was assessed against <i>Streptococcus mutans</i> and <i>Streptococcus sanguinis</i> by the broth microdilution method and agar cup diffusion test for the extracts and the mouthwash, respectively, demonstrating strong effectiveness against both oral streptococcus species. Results demonstrate the potential of HP and PPE in reducing oxidative stress, inflammation, and bacterial proliferation within oral mucosa, highlighting food waste up-cycling as a resource for human health.…”
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