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12161
Genomic insights into multidrug-resistant Acinetobacter baumannii strains isolated from Dhaka, Bangladesh
Published 2025-03-01“…Multidrug-resistant (MDR) A. baumannii is a growing concern to the healthcare system in Bangladesh, necessitating the elucidation of the genetic characteristics of this species. Five MDR, biofilm-forming A. baumannii strains isolated from clinical samples in Dhaka, Bangladesh, underwent a comprehensive whole-genome shotgun sequencing. …”
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12162
Microbiota Landscape of Gut System of Guppy Fish (Poecilia reticulata) Plays an Outstanding Role in Adaptation Mechanisms
Published 2019-01-01“…., Enterobacter spp, and Acinetobacter spp. are part of guppy gut microbiota. Some representative species are able to degrade and/or tolerate gasoline and/or diesel fuel hydrocarbons. …”
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12163
Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning
Published 2025-01-01“…Comparison of cellular evolution across species revealed that most lamprey cell types are homologous to those in jawed vertebrates. …”
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12164
Biomass Potentials and Carbon Storage of Wooden Plants in the Community Forest of Nglanggeran Village, Gunungkidul Regency, Yogyakarta
Published 2012-02-01“…The research result showed that there were 25 species of perennial woods, which cultivated by the community forest’s farmers in Nglanggeran Village, most of which is mahagony. …”
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12165
Anti-Inflammatory and Prebiotic Potential of Ethanol Extracts and Mucilage Polysaccharides from Korean Yams (<i>Dioscorea polystachya</i> and <i>Dioscorea bulbifera</i>)
Published 2025-01-01“…Among the extracts, the 95% ethanol extract exhibited the most potent inhibition of reactive oxygen species (ROS) and nitric oxide (NO) production, warranting further exploration of its mechanisms of action. …”
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12166
Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy
Published 2025-01-01“…Additionally, we identified novel recombination events, positive selection targets, and refined dating estimates for key events in the species’ history. Conclusions This study highlights the importance of considering methodological implications and reference genome bias in high-throughput sequencing-based whole-genome analysis of T. pallidum, especially of ancient or low-coverage samples, contributing to a deeper understanding of the treponemal pathogen and its subspecies.…”
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12167
TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes
Published 2025-02-01“…Methods In this study, we generated a TAB2 compound heterozygous knockout cell line in induced pluripotent stem cells (iPSCs) derived from a healthy individual using CRISPR/Cas9 technology. IPSCs are not species-dependent, are readily accessible, and raise fewer ethical concerns. …”
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12168
Unraveling nitrogen metabolism, cold and stress adaptation in polar Bosea sp. PAMC26642 through comparative genome analysis
Published 2025-01-01“…The average Nucleotide Identity (ANI) value is found to be below the threshold of 94-95%, indicating this bacterium might be a potential new species. This study is very helpful in determining the diversity of thiosulfate-oxidizing nitrate-reducing bacteria, as well as their ability to adapt to extreme environments. …”
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12169
New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels
Published 2025-02-01“…These findings enhance our understanding of how eelgrass adapts to the marine environment.DiscussionAs a marine monocotyledon, eelgrass is helpful to find conserved salt tolerance mechanisms by cross-species comparison. By examining the transcriptional responses of homologous genes in eelgrass, rice, and maize, we identified several groups of genes that are conserved in their response to salt stress. …”
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12170
The impact of dietary patterns on gut microbiota for the primary and secondary prevention of cardiovascular disease: a systematic review
Published 2025-01-01“…Changes in the relative abundance of the gut microbiome were summarized at various taxonomic levels, including phylum, class, order, family, genus, and species. Random-effects meta-analysis was conducted to analyze the mean difference in cardiometabolic parameters pre- and post-intervention. …”
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12171
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice
Published 2025-01-01“…This study investigates the effects of aminoguanidine hemisulfate (AGH), an inhibitor of reactive oxygen species (ROS), on mitochondrial autophagy, oxidative stress, and muscle force in mdx mice. …”
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12172
Exploring the capacity of microorganism treatment for fermentation and glycosidic aroma bioconversion from rose oil distillation wastewater
Published 2024-12-01“…The Damask rose (Rosa damascena Mill.) is a valuable species of aromatic rose that is grown in specific floriculture regions of Iran for the extraction of essential oils or preparation of rose water. …”
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12173
The Campylobacter jejuni BumS sensor phosphatase detects the branched short-chain fatty acids isobutyrate and isovalerate as direct cues for signal transduction
Published 2025-02-01“…ABSTRACT Two-component signal transduction systems (TCSs) are nearly ubiquitous across bacterial species and enable bacteria to sense and respond to specific cues for environmental adaptation. …”
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12174
Moxibustion Regulates the BRG1/Nrf2/HO-1 Pathway by Inhibiting MicroRNA-222-3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis-Associat...
Published 2024-01-01“…With changes in reactive oxygen species (ROS), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and inflammatory cytokines interleukin (IL)-1β and tumor necrosis factor (TNF)-α), we verified that HPM protects against oxidative stress and inflammation in IECs of UC and CAC mice. …”
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12175
Structure of a Sulfated Capsular Polysaccharide from the Marine Bacterium <i>Cobetia marina</i> KMM 1449 and a Genomic Insight into Its Biosynthesis
Published 2025-01-01“…Comparative analysis of the CPS BGCs from available <i>Cobetia</i> genomes showed the presence of KMM 1449-like CPS BGC among strains of all three <i>Cobetia</i> species. The study of new natural sulfated polysaccharides, as well as the elucidation of the pathways of their biosynthesis, provides the basis for the development of potential anticancer drugs.…”
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12176
Evaluation of chitinase production ability to antagonize Pyricularia Oryzae of bacteria and actinomycete strains isolated from rice root soil in Kien Giang Province
Published 2024-09-01“…The mechanism of the infection is directing penetration through the plasma membrane, secreting cytotoxins, and forming infectious cells specialized for causing disease in rice plants in some species (Muni & Nadarajah, 2014). Therefore, biological products containing microorganisms that can antagonize fungal pathogens and are environmentally friendly, are promising measure to control this disease. …”
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12177
Synergistic Antimicrobial Effect of Raspberry (Rubus idaeus L., Rosaceae) Preparations and Probiotic Bacteria on Enteric Pathogens
Published 2021-02-01“…The combined action of LAB (lactic acid bacteria) and raspberry preparations on the pathogenic species was also evaluated. The results of our study showed no or weak antibacterial effect of raspberry preparations on the pathogenic bacteria tested. …”
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12178
Dissecting the role of single nucleotide polymorphism of lymphotoxin beta gene during pig domestication using bioinformatic and experimental approaches
Published 2016-01-01“…The rs340283541 SNP occurs in a DNA motif highly conservative among 11 mammalian species; thus, it may be of functional significance. …”
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12179
Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction
Published 2024-12-01“…Results In vitro, irisin mitigated HSC activation and reduced reactive oxygen species associated with the TGF-β1/Smad signaling pathway. …”
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12180
<i>Botrytis cinerea</i> PMT4 Is Involved in <i>O</i>-Glycosylation, Cell Wall Organization, Membrane Integrity, and Virulence
Published 2025-01-01“…Using bioinformatics analysis within the <i>Botrytis cinerea</i> genome database, an ortholog to <i>Saccharomyces cerevisiae</i> Pmt4 and other fungal species was identified. The aim of this study was to assess the relevance of the <i>bcpmt4</i> gene in <i>B. cinerea</i> glycosylation. …”
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