Resiquimod induces a mixed Th1 and Th2 response via STAT1 and STAT3 signalling in chickens by Deepthi Kappala, Saravanan Ramakrishnan, Patel Nikunjkumar Prakashbhai, Abinaya Kaliappan, Prasad Thomas, Jörg Linde, Mithilesh Singh, Sohini Dey, Madhan Mohan Chellappa

“…These insights provide a foundation for optimizing R-848 as an immunomodulatory agent in avian species.…”
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In vitro inhibition of Xanthomonas vasicola pv. musacearum, the causal agent of banana Xanthomonas Wilt, using medicinal plant extracts from North Kivu, Eastern Democratic Republic... by Franchement Mukeshambala, Angele Ibanda, Ludivine Lassois, Gakuru Semacumu, Dhed’a Djailo, Leon Nabahungu, Guy Blomme, Godefroid Monde

“…Of the thirteen plant species identified as effective against the pathogen, the Myrtaceae and Euphorbiaceae families were the most represented. …”
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Gross soil N transformations and microbial communities in Luxembourg beech forest (Fagus sylvatica L.) soils along a pH gradient by Mengru Jia, Annemieke Kooijman, Roland Bol, Wim W. Wessel, Kathrin Hassler, Albert Tietema

“…Net N release was restricted to the mineral topsoil, shifting from low ammonium and nitrate release in acidic soils, to substantial nitrate release in calcareous soils, potentially supporting greater plant species richness at high pH. Our results demonstrate that soil N supply mechanisms differ markedly along the pH gradient, from low immobilization at low pH to high nitrification at high pH, driven by shifts in fungal versus bacterial dominance and their distinct N demands. …”
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Pharmacokinetics of Immediate and Sustained Release Cephalexin Administered by Different Routes to Llamas (Lama glama) by Verónica Kreil, Luis Ambros, Ana Paula Prados, Lisa Tarragona, Agustina Monfrinotti, Guillermo Bramuglia, Marcela Rebuelto

“…We investigate the pharmacokinetics of two different cephalexin formulations administered to llamas by the intravenous (IV), intramuscular (IM), and subcutaneous (SC) routes, the minimum inhibitory concentration (MIC) of cephalexin against some Escherichia coli and staphylococci isolated from llamas, and we apply the PK/PD modelling approach, so that effective dosage recommendations for this species could be made. Six llamas received immediate (10 mg/kg, IV, IM, and SC) and sustained (8 mg/kg IM, SC) release cephalexin. …”
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Phytochemical and toxicological evaluation of aqueous leaf extract of Premna integrifolia L. in male balb/c mice by Suman, Pratibha Gaurav, Rajesh Saini, Kavindra Nath Tiwari, Gautam Geeta Jiwatram

“…The parameters studied included total reactive oxygen species (ROS) production, apoptosis, cell viability percentage, and cellular morphology. …”
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POPULATION GENETICS STUDY OF THE WHEAT LEAF RUST AGENT PUCCINIA TRITICINA IN DAGESTAN by E. I. Gultyaeva, E. L. Shaydayuk, K. M. Abdullaev

“…Germplasm collections of bread wheat and other Triticum and  Aegilops species are studied every year in the experimental field at  the Dagestan Experimental Station of VIR (DES VIR), and evaluated  for leaf rust resistance. …”
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Characteristics, location, and usage patterns of resting burrows in Chinese pangolins: Insights from radio-telemetry tracking by Nick Ching-Min Sun, Jing-Shiun Lin, Kurtis Jai‑Chyi Pei

“…These results provide valuable insights into the usage patterns of resting burrows, thus enriching the understanding of pangolin behavior, ecological requirements and conservation strategies for this endangered species.…”
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Molecular identification of the stem rust resistance genes in the introgression lines of spring bread wheat by O. A. Baranova, S. N. Sibikeev, A. E. Druzhin

“…The lines were obtained with the participation of CIMMYT synthetics, durum wheat cultivars, direct crossing with Agropyron elongatum (CI-7-57) and have introgressions from related species of bread wheat, namely translocations from Ag. elongatum (7DS-7DL-7Ae#1L), Aegilops speltoides (2D-2S), Ae. ventricosum (2AL-2AS-2MV#1), Secale cereale (1BL-1R#1S), 6Agi (6D) substitution from Ag. intermedium and triticale Satu. …”
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Adipokines regulate the development and progression of MASLD through organellar oxidative stress by Ke Zhao, Heng Zhang, Wenyu Ding, Xiaoshuai Yu, Yanli Hou, Xihong Liu, Xinhua Li, Xiaolei Wang

“…This review examines recent data, underscoring the critical interplay of oxidative stress, reactive oxygen species, and redox signaling in adipokine-mediated mechanisms. …”
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<i>o</i>-Halogenation and -Alkoxylation of Phenylglycine Derivatives by Pd-Mediated C-H Functionalization: Scope and Limitations by Eduardo Laga, Sonia Nieto, Carlos Cativiela, Esteban P. Urriolabeitia

“…A partial loss of the enantiomeric excess is observed when the starting phenylglycine is enantiomerically pure, this arising from the formation of bridging azavinylidene (<b>6</b>) and imine intermediate species (<b>7</b>), which were characterized by X-ray diffraction methods.…”
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Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine by Shiqi Zhang, Emmanouil Ntasis, Sarah Kabtni, Jaap van den Born, Gerjan Navis, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

“…Iron has been suggested to affect the clinical course of type 2 diabetes (T2DM) as accompanying increased intracellular iron accumulation may provide an alternative source for reactive oxygen species (ROS). Although carnosine has proven its therapeutic efficacy in rodent models of T2DM, little is known about its efficacy to protect cells from iron toxicity. …”
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Rose cultivars for biomonitoring of air quality by Wanjala Sylvia Nafula, László Orlóci, Szilvia Kisvarga, Gábor Boronkay, Béla Tóthmérész, Stewart Ajele, Vanda Éva Abriha-Molnár, Edina Simon

“…Planting rose cultivars in urban green spaces alongside established species that are tolerant to polluted air provides a good opportunity for bioindication. …”
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Development of a colloidal gold immunochromatographic assay utilizing dual-antibody sandwich method for detecting Orientia tsutsugamushi by Qingyu Lu, Shiyin Yu, Sibo Wang, Min Cao, Liuxin Li, Miao Xin, Weilong Tan, Yong Qi, Yichen Lu, Xiaohui Xiong

“…The assay also exhibited exceptional specificity, with no false positives observed against other bacterial species, including Escherichia coli, Salmonella, Staphylococcus aureus, and Listeria monocytogenes. …”
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Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

“…Here, we collect roots and rhizosphere soils from nine Populus species belonging to four sections (Leuce, Aigeiros, Tacamahaca, and Turanga), generate metabolite and transcription data for roots and microbiota data for rhizospheres, and conduct comprehensive multi-omics analyses. …”
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Antibacterial activity and impact on keratinocyte cell growth of Cutibacterium acnes bacteriophages in a Cutibacterium acnes IA1- colonized keratinocyte model by Juan C Farfán-Esquivel, María Victoria Gutiérrez, Alejandro Ondo-Méndez, John M González, Martha J Vives-Flórez

“…Phage therapy has been proposed as an alternative treatment for acne, given its species-specificity to kill bacteria, its relative innocuity, and its potential to manage antibiotic-resistant pathogens. …”
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Cold-induced metabolic adaptations in the large yellow croaker Larimichthys crocea by Yang Gao, Huirong Lv, Chengzhang Huang, Xiaoyu Qu, Zhangjie Chu, Weiye Li, Xiaolong Yin, Jungyeol Park, Dejun Feng, Junwook Hur

“…Large yellow croaker is one of the most important marine aquaculture species in China. However, due to its intolerance to low temperatures, overwintering often results in deaths, causing significant economic losses. …”
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Tear Film Proteome of Healthy Domestic Cats by Jéssica Fontes Veloso, Paula Elisa Brandão Guedes, Luciana Carvalho Lacerda, Juliano Oliveira Santana, Irma Yuliana Mora-Ocampo, Carlos Priminho Pirovani, Arianne Pontes Oriá, Alexandre Dias Munhoz, Renata Santiago Alberto Carlos

“…Others were considered novel in tear film samples of all species: cyclin-dependent protein kinase, serine/arginine repetitive matrix protein, apelin receptor, secretory protein related to C1q/TNF, Wee1, α-1,4 glucan phosphorylase, and WD repeat domain 1. …”
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Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity by Wassim Daher, Vincent Le Moigne, Yara Tasrini, Shweta Parmar, Danielle L. Sexton, John Jairo Aguilera-Correa, Valentin Berdal, Elitza I. Tocheva, Jean-Louis Herrmann, Laurent Kremer

“…Five subtypes (ESX-1 to ESX-5) exist, each with specific roles and well-characterized secretion profiles in various mycobacterial species. Mycobacterium abscessus, encodes only ESX-3 and ESX-4. …”
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ROS-mediated M1 polarization-necroptosis crosstalk involved in Di-(2-ethylhexyl) phthalate-induced chicken liver injury by Guangxing Li, Menglin Wu, Kaiting Chen, Yue Xu, Xiandan Zhang, Yang Chen, Hong Zhang, Ruili Zhang, Xiaodan Huang

“…Further studies revealed the increase of reactive oxygen species (ROS) level and malonaldehyde (MDA) content, and the decrease of total antioxidant capacity (T-AOC) level, total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px) activities, which led to excessive oxidative stress in the liver. …”
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Thermal performance analysis capturing variable liquid characteristics based on chemically reactive rheological liquid with diffusive-thermo and thermo-diffusive effect by Attia Boudjemline, M. Waqas, Nurnadiah Zamri, Mohammed Jameel, Hala A. Hejazi, Saidani Taoufik, Meznah M. Alanazi, Oqila Ganiyeva

“…Such reaction can considerably affect the diffusion together with flow aspects within boundary-layer, influencing factors like species concentrations and temperature. Such interactions are indispensable in distinct engineering utilizations, containing environmental engineering and chemical reactors scenarios. …”
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