Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage by Shan Tian, Ruixue Li, Jiao Li, Jinhui Zou

“…Compared to the normal control group, mice in the PS-NPs group exhibited more tumor nodes and reactive oxygen species (ROS), higher expression of pan-CK and Ki-67, and more severe DNA damage. 16S rRNA sequencing revealed that exposure to PS-NPs altered the abundance of Allobaculum and Lactobacillus, whereas metabolic analysis showed that the most significant metabolites were enriched mostly in fatty acid metabolism. …”
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Accumulation of advanced oxidative protein products exacerbate satellite glial cells activation and neuropathic pain by Chen Tu, Shi-Cheng Wang, Meng-Xuan Dai, Si-Qi Lai, Zhi-Wei Huang, Yong-Peng Yu, Yun-Biao Chen, Ji-Huan Zeng, Liang Wang, Zhao-Ming Zhong

“…Exogenous AOPPs activated SGCs, increased reactive oxygen species and inflammatory response, upregulated the RAGE, and activated NF-κB signaling. …”
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The Association of Mitochondrial tRNACys G5783A Mutation with Major Depressive Disorder in Two Han Chinese Families by Jing P, Yu H, Sun W, Liang M, Xia T, Yang H, Chen P, Li J, Zhang X

“…This mutation was found at a highly conserved cytosine at position 50 (C50) in the TΨC stem of tRNACys, with a conserved coefficient of 100% across 17 species. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.Conclusion: The identification of the tRNACys G5783A mutation in two unrelated individuals with depression strongly suggests that this mutation may play a role in the development of major depressive disorder (MDD). …”
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Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK‐fusion‐positive lung cancer... by Koh Furugaki, Takaaki Fujimura, Narumi Sakaguchi, Yasutaka Watanabe, Ken Uchibori, Eisaku Miyauchi, Hidetoshi Hayashi, Ryohei Katayama, Shigeki Yoshiura

“…GPX4 was found to be upregulated in DTP cells and to promote cell survival by suppressing reactive oxygen species (ROS) accumulation; GPX4 inhibitors blocked this upregulation and facilitated ROS‐mediated cell death. …”
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Targeting Nrf2/KEAP1 signaling pathway using bioactive compounds to combat mastitis by Muhammad Zahoor Khan, Liangliang Li, Yandong Zhan, Huang Binjiang, Xiaotong Liu, Xiyan Kou, Adnan Khan, Abdul Qadeer, Qudrat Ullah, Khalid J. Alzahrani, Tongtong Wang, Changfa Wang, Muhammad Zahoor

“…Elevated reactive oxygen species (ROS) followed by oxidative stress, apoptosis, inflammatory changes and suppressed immunity are considered the key biomarkers observed during mastitis. …”
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Identification of compounds against atherosclerosis induced by ox-LDL based on cell extraction/UPLC–MS/MS from mulberry twigs and their mechanistic analysis by Zhihui Jin, Wei Xiang, Xiaowen Shi, Fenglin Jiang, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Xianzhi Huang, Li Xu

“…Protective effects were assessed by measuring cell viability, malondialdehyde (MDA), and superoxide dismutase (SOD) levels, along with detecting intracellular reactive oxygen species (ROS) using 2, 7-dichlorodihydrofluorescein diacetate (DCFH-DA) and dihydroethidine (DHE) probes. …”
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First Molecular Identification of <i>Entamoeba</i> spp. in Sheep, Beef Cattle, and Dairy Cattle in Shanxi Province, North China by Ze-Xuan Wu, Han-Dan Xiao, Yuan-Hui He, Shi-Bo Huang, Jing Li, Yu Kang, Wen-Bin Zheng, Xing-Quan Zhu

“…According to the obtained SSU rRNA sequences, several <i>Entamoeba</i> species, namely <i>Entamoeba bovis</i>, <i>Entamoeba</i> Ribosomal Lineage (RL) 2, <i>Entamoeba</i> RL4, and <i>Entamoeba</i> RL8, were identified. …”
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SNX30 inhibits lung adenocarcinoma cell proliferation and induces cell ferroptosis through regulating SETDB1 by Xinjie Fan, Qichu Zhu, Chengzhuo Du, Jinlai Chen, Yingming Su

“…The intracellular levels of total iron and Fe2+ were detected using Iron Assay Kits. Reactive oxygen species (ROS) levels were evaluated using a DCFH-DA probe and flow cytometry. …”
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Evaluation of the Urine POC-CCA Test Accuracy in the Detection of Schistosoma mansoni Infection: A Systematic Review and Meta-Analysis by Getaneh Alemu, Endalkachew Nibret

“…Schistosomiasis is a common public health problem throughout the world and Schistosoma mansoni is the most prevalent species in Africa. Most endemic countries use the Kato–Katz (KK) stool smear examination for diagnosis, mapping, and monitoring of intervention programs. …”
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Gross and Histopathology of Goats Feeding on Opuntia stricta in Laikipia County, Kenya by Jackson M. Ncebere, Paul G. Mbuthia, Robert M. Waruiru, Peter K. Gathumbi

“…Various plant species such as Opuntia stricta have developed defensive measures, namely, spines, thorns, and other sharp pointed structures to protect themselves from herbivores and other animals feeding on them. …”
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1-Methylcyclopropene Delays Browning and Maintains Aroma in Fresh-Cut Nectarines by Rui Zhang, Ze Miao, Shuang Xie, Jiao Li, Sheng Tao, Yuqian Jiang, Lingling Pang, Lihua Duan, Xihong Li

“…Compared with the control, 1-MCP pre-cutting treatment maintained the ultrastructural integrity of the cell wall in fresh-cut nectarines, which also showed reduced malondialdehyde (MDA) content and reactive oxygen species (ROS) and enhanced the 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) radical scavenging activities. …”
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Variability in Morphological Traits and Nutritional Profiles of Adult <i>Eriocheir sinensis</i> in Different Aquacultural Regions by Wenrong Feng, Qinghong He, Jianlin Li, Jun Zhou, Guoan Hua, Yuanfeng Xu, Gang Jiang, Yongkai Tang

“…<i>Eriocheir sinensis</i> is a species of significant economic importance in China’s aquaculture industry. …”
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Synthetic Hydrogel Dilutes <i>Serratia plymuthica</i> Growth— Promoting Effect on <i>Brassica napus</i> L. Under Drought Conditions by Grażyna B. Dąbrowska, Daniel Krauklis, Milena Kulasek, Magdalena Nocny, Marcel Antoszewski, Agnieszka Mierek-Adamska, Beata Kaliska

“…The seed viability test, reactive oxygen species accumulation, and SOD activity showed no adverse effects of applying hydrogel to canola seeds. …”
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Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A... by Hasan H. Bahjat, Raid A. Ismail, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohsen Al-Omar, Salman A. A. Mohammed, Riaz A. Khan

“…The NPs showed antimicrobial activities against the pathogenic species: Escherichia coli and Staphylococcus aureus. …”
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Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway by Xiaoyu Zhang, Ping Zhu, Xiuying Zhang, Yina Ma, Wenguang Li, Ji-Mei Chen, Hui-Ming Guo, Richard Bucala, Jian Zhuang, Ji Li

“…Isoliquiritigenin (ISL), a simple chalcone-type flavonoid, is derived from licorice compounds and is mainly present in foods, beverages, and tobacco. Reactive oxygen species (ROS) is a critical factor involved in modulating cardiac stress response signaling during ischemia and reperfusion. …”
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Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization by Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, Fuyuki Tokumasu

“…Abstract The rapid intraerythrocytic replication of Plasmodium falciparum, a deadly species of malaria parasite, requires a quick but constant supply of phospholipids to support marked cell membrane expansion. …”
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Systematic identification of the chemical components of leaves and roots of Didymocarpus heucherifolius Hand.-Mazz. based on UHPLC Q-Exactive Orbitrap MS technology coupled with mo... by Liangyin Shu, Shunli Xiao, Kailin Li, Huibin Luo, Meng Li, Qingrui Yang, Bowen Gao, Jiaxin Li, Fang Yan, Wei Cai

“…-Mazz. is plant of the genus Didymocarpus wall. (Gesneriaceae). Species in this genus have long been used in folk medicine to treat various illnesses, including wounds, kidney stones, inflammations, asthma, influenza, etc. …”
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Correlation Between <i>Cryptococcus</i> Infection and the Nasal Mycobiota in a Population of Free-Ranging Koalas (<i>Phascolarctos cinereus</i>) in New South Wales, Australia by Andrew S. McPherson, Sophie L. Haworth, Alex Kan, Luisa Monteiro de Miranda, Mark B. Krockenberger

“…Cryptococcosis is a fungal disease in humans and animals, caused by the <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i> species complexes. Clinical cryptococcosis primarily manifests as upper respiratory tract disease; however, dissemination to other organs, particularly the brain, can occur. …”
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Determination of Carbapenemase-Producing OXA- 48 and KPC Genes in Antibiotic-Resistant Gram-Negative Bacilli Isolated from Infectious Samples of Cardiovascular Patients Hospitalize... by Mina Owrang, Ebrahim Taheri Hossein Abad, Shakiba Shafaie

“…In contrast, the KPC gene was not detected in any of the isolates. Among the bacterial species analyzed, the highest frequency of the OXA-48 gene was observed in Enterobacter isolates. …”
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Evolutionary analysis of genes associated with the sense of balance in semi-aquatic mammals by Yuehuan Dong, Qinguo Wei, Guolei Sun, Xiaodong Gao, Tianshu Lyu, Lidong Wang, Shengyang Zhou, Xibao Wang, Yongquan Shang, Lupeng Shi, Honghai Zhang

“…Results We selected 42 mammal species across 20 orders, 38 families, and 42 genera for analysis. …”
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