ICOS Potenza (Italy) Atmospheric Station: A New Spot for the Observation of Greenhouse Gases in the Mediterranean Basin by Emilio Lapenna, Antonella Buono, Alessandro Mauceri, Isabella Zaccardo, Francesco Cardellicchio, Francesco D’Amico, Teresa Laurita, Davide Amodio, Canio Colangelo, Gianluca Di Fiore, Antonella Gorga, Ermann Ripepi, Francesco De Benedictis, Silvana Pirelli, Liborio Capozzo, Vincenzo Lapenna, Gelsomina Pappalardo, Serena Trippetta, Lucia Mona

“…The Integrated Carbon Observation System (ICOS) is the reference Research Infrastructure (RI) for the observation of greenhouse gases (GHGs) across Europe, providing standardised, long-term and high-precision measurements of the most relevant species (CO₂, CH₄, CO, etc.). …”
Get full text

An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

“…Furthermore, QM-DMAC effectively generates reactive oxygen species (ROS) under white light irradiation, which precisely induces ROS-mediated lysosomal membrane permeabilization (LMP) and lysosome rupture. …”
Get full text

Pathogenic potential of ornithogenic <i>Escherichia coli</i> strains detected in the Earth's polar regions by Batyrbek I. Aslanov, Daniil V. Azarov, Maria A. Makarova, Elizaveta G. Marysheva, Lyudmila A. Kraeva, Aleksey S. Mokhov, Ekaterina A. Lebedeva, Nikita E. Goncharov, Natalya V. Lebedeva, Dmitry A. Starikov, Victoria V. Kolodzhieva, Dmitry E. Polev, Artemy E. Goncharov

“…Migratory bird colonies and high latitude avian colonies may be points of active intraspecies and interspecies contact between different animal species, accompanied by the spread of pathogens. At the same time, the phylogeography of E. coli in relation to the presence of natural foci of colibacillosis in polar regions remains virtually unstudied. …”
Get full text

ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation by Li-Quan Huang, Ting-Xuan Yan, Bao-Sheng Wang, Hao Li, Nai-Bao Zhou

“…Subsequently, we made a novel discovery that ZC3H15 knockdown mice with BCP displayed improved neuronal oxidative stress and reactive oxygen species (ROS) generation in spinal cord tissues, which was confirmed in H2O2-treated mouse spinal cord neurons primarily through mediating the kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor, erythroid 2-like transcription factor 2 (NRF2) pathway. …”
Get full text

Modeling Seed Longevity and Percentile Prediction: A Sigmoidal Function Approach in Soybean, Maize, and Tomato by Felipe Souza Carvalho, Brunna Rithielly Rezende, Amanda Rithieli Pereira dos Santos, Maria Márcia Pereira Sartori

“…Modeling seed longevity using sigmoidal models can significantly contribute to determining various viability percentiles, supporting storage practices and providing valuable insights for strategic decision-making in seed management, proving useful in both commercial and species conservation contexts.…”
Get full text

Development of a set of monosomic alien addition lines from Gossypium raimondii in Gossypium hirsutum toward breeding applications in cotton by Zhenzhen Xu, Xiaoxi Lu, Wenjie Ding, Wei Ji, Wuzhimu Ali, Heyang Wang, Shan Meng, Qi Guo, Peng Xu, Xianglong Chen, Liang Zhao, Huan Yu, Xinlian Shen

“…These MAALs will provide important genetic bridge materials for gene transfer from G. raimondii as well as for the study of Gossypium species genomes and their evolution. Conclusions A set of Gossypium hirsutum - Gossypium raimondii MAALs were developed and they showed abundant variation in morphological, agronomic, yield, and fiber quality traits, as well as in drought and salt resistance at seedling stage.…”
Get full text

Construction of Multi-level Ecological Corridor System for National Parks: A Case Study of the Proposed Nanling National Park by Yi DENG, Zeyu HUANG, Ziyi MAO, Jinling HUANG

“…At the park level, ecological source areas are identified based on species habitat suitability. The method of future scenario simulation is introduced in the identification of ecological source areas, and the future environmental data are obtained through two climate models (ssp126 and ssp585) and related plans. …”
Get full text

Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immun... by Qian Yang, Ruijing Zhang, Peng Tang, Yu Sun, Candice Johnson, Jason Saredy, Susu Wu, Jiwei Wang, Yifan Lu, Fatma Saaoud, Ying Shao, Charles Drummer, Keman Xu, Daohai Yu, Rongshan Li, Shuping Ge, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We made the following findings: (1) LIUS upregulates proinflammatory IGs and downregulates metastasis genes in cancer cells, and LIUS upregulates adaptive immunity pathways but inhibits danger-sensing and inflammation pathways and promote tolerogenic differentiation in bone marrow (BM) cells. (2) LIUS upregulates IGs encoded for proteins localized in the cytoplasm, extracellular space, and others, but downregulates IG proteins localized in nuclear and plasma membranes, and LIUS downregulates phosphatases. (3) LIUS-modulated IGs act partially via several important pathways of reactive oxygen species (ROS), reverse signaling of immune checkpoint receptors B7-H4 and BTNL2, inflammatory cytokines, and static or oscillatory shear stress and heat generation, among which ROS is a dominant mechanism. (4) LIUS upregulates trained immunity enzymes in lymphoma cells and downregulates trained immunity enzymes and presumably establishes trained tolerance in BM cells. (5) LIUS modulates chromatin long-range interactions to differentially regulate IGs expression in cancer cells and noncancer cells. …”
Get full text

Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosisResearch in context by Stylianos Papadopoulos, David Hardy, Frédérique Vernel-Pauillac, Magali Tichit, Ivo G. Boneca, Catherine Werts

“…Humans are susceptible to leptospirosis; infection with Leptospira interrogans species can cause severe disease in humans, with multi-organ failure, mainly affecting kidney, lung and liver function, leading to death in 10% of cases. …”
Get full text

Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation by S.H. Larekeng, M. Nursaputra, M.F. Mappiasse, S. Ishak, M. Basyuni, E. Sumarga, V.B. Arifanti, A.A. Aznawi, Y.I. Rahmila, M. Yulianti, R. Rahmania, A. Mubaraq, S.G. Salmo III, H. Ali, I. Yenny

“…Field surveys were conducted to determine the species composition of each mangrove stand and measure their diameter at breast height. …”
Get full text

Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids by Shelley Barnhart, Masami Shimizu-Albergine, Eyal Kedar, Vishal Kothari, Baohai Shao, Melissa Krueger, Cheng-Chieh Hsu, Jingjing Tang, Jenny E. Kanter, Farah Kramer, Danijel Djukovic, Vadim Pascua, Yueh-Ming Loo, Lucrezia Colonna, Sadie J. Van den Bogaerde, Jie An, Michael Gale, Jr., Karen Reue, Edward A. Fisher, Sina A. Gharib, Keith B. Elkon, Karin E. Bornfeldt

“…Taking advantage of a myeloid cell-targeted ACSL1-deficient mouse model and a series of lipidomics, proteomics, metabolomics and functional analyses, we show that IFN-I leverages induction of ACSL1 to increase accumulation of fully saturated phosphatidic acid species in macrophages. Conversely, ACSL1 induction is not needed for IFN-I’s ability to induce the prototypical IFN-stimulated protein signature or to suppress proliferation or macrophage metabolism. …”
Get full text

BP-3 exposure at environmentally relevant concentrations induced male developmental reproductive toxicity via ER/CCL27/ROS pathway in mice by Hong-Mei Li, Yan-Rong Gao, Qing Chang, Xiu-Ying Pei, Jia-He Sun, Yu-Jia Lin, Ya-Nan Tian, Qiang-Wang, Bin Zhao, Heidi Qunhui Xie, Hui-Ming Ma, Hai-Ming Xu

“…Mechanistically, BP-3 directly interacted with ER, which boosted CCL27 expression, reactive oxygen species (ROS) accumulation, and BTB and cytoskeleton impairment. …”
Get full text

Deep application of controlled-release urea increases the yield and saponin content of Panax notoginseng by regulating soil nitrate distribution by Yun-xia Su, Yun-xia Su, Yun-xia Su, Ping Zhao, Li-jie Jia, Li-jie Jia, Li-jie Jia, Yuan-feng Cao, Guan-ze Liu, Guan-ze Liu, Jun-wen Chen, Jun-wen Chen, Sheng-chao Yang, Sheng-chao Yang, Yan-li Zhou, Guang-qiang Long, Guang-qiang Long, Guang-qiang Long

Get full text

Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…Introduction: The white shrimp, Litopenaeus vannamei has become a popular species for aquaculture worldwide due to its euryhaline nature and commercial importance. …”
Get full text

Vingt années de recherches à Oedenburg (Biesheim et Kunheim, Haut-Rhin) : un bilan by Michel Reddé

“…Faunal studies revealed the role of wild species (birds and fish) in the meat diet, which are rarely brought to light without wet sieving.The departure of the troop, during the conquest of the “Agri decimates”, at the beginning of the reign of Vespasian, did not mark the end of the civil agglomeration. …”
Get full text

A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

“…Methods: We developed the bioinformatics pipeline diphtOscan (available at https://gitlab.pasteur.fr/BEBP/diphtoscan) to extract from genomes of Corynebacteria of the diphtheriae species complex, medically relevant features including tox gene presence and disruption. …”
Get full text

Infection Frequency and Allelic Variants of <em>Toxoplasma gondii</em> in Wildlife from the Panama Canal Zone by Evelyn Henríquez-Carrizo, Hector Cruz, Alessandra Jurado, Diorene Smith, Delba Villalobos-Cerrud, Lorena Fábrega, Carolina de la Guardia, Ryan Cano, Ricardo Correa, Edy Frías, Anabel Argelis García, Nivia Ríos, Nidia Sandoval, Alex O. Martínez Torres, Armando Castillo-Pimentel, Zuleima Caballero E.

“…Panama has a large number of wild animal species, which could host a highly diverse amount of genetic variants of <i>Toxoplasma gondii</i> (<i>T. gondii</i>). …”
Get full text

The use of antimicrobials in Italian buffalo farms by Gabriele Di Vuolo, Federico Scali, Claudia Romeo, Valentina Lorenzi, Chiara D. Ambra, Maria Serrapica, Giovanna Cappelli, Francesca Fusi, Esterina De Carlo, Giovanni Loris Alborali, Luigi Bertocchi, Domenico Vecchio

“…Although direct comparisons may have some limitations, AMU seems to be lower in buffalo than in other species reared in Italy as reported in the bibliography (Mazza et al. 2021). …”
Get full text

A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial by Xiaorong Wu, Alvin Surya Tjahyo, Vera Sergeyevna Brok Volchanskaya, Long Hui Wong, Xianning Lai, Yi Ning Yong, Farhana Osman, Shia Lyn Tay, Priya Govindharajulu, Shalini Ponnalagu, Rachel Tso, Hwee Sze Teo, Kaijie Khoo, Huan Fan, Chew Chan Goh, Clara Poh Lian Yap, Melvin Khee-Shing Leow, Christiani Jeyakumar Henry, Sumanto Haldar, Kevin Junliang Lim

“…The IG had significantly greater reductions in LDL cholesterol (q (Treatment×Time) = 0.01, β  = -0.16), total cholesterol (q (Treatment×Time) = 0.02, β  = -0.3) and HbA1c (q (Treatment×Time) = 0.04, β  = -0.004) compared with CG, alongside increases in fiber degrading species in IG, mediated through metabolites such as bile acids and amino acids. …”
Get full text

Genetic and Molecular Characterization of Avian Influenza A(H9N2) Viruses from Live Bird Markets (LBM) in Senegal by Mamadou Malado Jallow, Moussa Moise Diagne, Marie Henriette Dior Ndione, Mamadou Aliou Barry, Ndiendé Koba Ndiaye, Davy Evrard Kiori, Marie Pedapa Mendy, Déborah Goudiaby, Gamou Fall, Malick Fall, Ndongo Dia

“…Overall, our findings highlight the potential for cross-species transmission of Senegalese A/H9N2 viruses, emphasizing the need for sustained monitoring of these viruses in both animal and human populations.…”
Get full text