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10721
Self-Assembly Iron Oxide Nanoclusters for Photothermal-Mediated Synergistic Chemo/Chemodynamic Therapy
Published 2021-01-01“…Superparamagnetic iron oxide nanoclusters (SPIOCs) were located within the core, which resulted in high photothermal conversion and outstanding generation of reactive oxygen species (ROS). The shell consisted of a human serum albumin- (HSA-) paclitaxel (PTX) layer, which extended the blood circulation time and ensured the effectiveness of the chemotherapy. …”
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10722
The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites
Published 2025-01-01“…Signal-dependent transport into and out of the nucleus mediated by members of the importin (IMP) superfamily is crucial for eukaryotic function, with inhibitors targeting IMPα being of key interest as anti-infectious agents, including against the apicomplexan <i>Plasmodium</i> species and <i>Toxoplasma gondii</i>, causative agents of malaria and toxoplasmosis, respectively. …”
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10723
Risk of Fungi Associated with Aflatoxin and Fumonisin in Medicinal Herbal Products in the Kenyan Market
Published 2017-01-01“…Utilization of herbal products is a major concern due to the possibility of contamination by toxigenic fungi that are mycotoxin producers such as Aspergillus species during processing and packaging. Research was carried out to determine the presence of aflatoxins and fumonisins in herbal medicinal products sold in Eldoret and Mombasa towns in Kenya. …”
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10724
Kinetic and isotherm studies of nickel and cadmium ions adsorption onto Clay-Chitosan composite
Published 2025-01-01“…They contaminate ecosystem, endangering the survival of many species, including humans. In this study, a novel clay-chitosan composite was prepared and characterized to evaluate its adsorption potential for the removal of these pollutants. …”
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10725
Climate Change and Environmental Influence on Prevalence of Visceral Leishmaniasis in West Pokot County, Kenya
Published 2022-01-01“…Kala-azar is a parasitic disease caused by Leishmania species transmitted by sand fly. In Kenya, kala-azar is endemic in thirty subcounties spread over in eleven counties in the arid zones. …”
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10726
Toll-like receptor 4 pathway evolutionary trajectory and functional emergence
Published 2025-01-01“…While the critical residues of TIRAP, TRIF, and MyD88 were preserved, we also found that the important residues of TRAM signaling were not conserved in C. milli.DiscussionThis suggests the presence of functional TIRAP–MyD88-mediated TLR4 signaling and TRIF-mediated TLR3 signaling in the ancestral species. The overall biological function of this signaling domain appears to be gradually acquired through the orchestration of several motifs through an evolutionary scale.…”
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10727
Molecular Evidence of Emerged Pulmonary Lophomoniasis due to Lophomonas blattarum among Hospitalized Patients in Southwestern Iran: A National Registry-Based Study
Published 2022-01-01“…Also, based on sequencing data and blast analysis, the presence of L. blattarum species was confirmed. The average age of Lophomonas spp.‐ positive patients was 67.02 ± 15.14 years. …”
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10728
Heme Oxygenase 1/Peroxisome Proliferator-Activated Receptor Gamma Pathway Protects Intimal Hyperplasia and Mitigates Arteriovenous Fistula Dysfunction by Regulating Oxidative Stres...
Published 2022-01-01“…After AVF was established, the levels of transforming growth factor-β (TGF-β), interleukin-1β (IL-1β), interleukin-18 (IL-18), and reactive oxygen species (ROS) were significantly increased (P<0.05), and HO-1 normal expression and COPP pretreatment evidently decreased their levels in AVF (P<0.05). …”
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10729
Diversity and antimicrobial resistance profiles of Mycobacterium avium complex clinical isolates in Thailand based on whole genome comparative analysis
Published 2025-01-01“…Whole-genome average nucleotide identity (ANI) revealed the MAC species distribution, comprising 54 (81.8%) M. intracellulare, 6 (9.1%) M. avium, 5 (7.6%) M. colombiense, and 1 (1.5%) M. timonense. …”
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10730
Integrated Pest Management of Wireworms in Potatoes: Use of Tolerant Varieties to Implement Damage Prevention
Published 2024-12-01“…The prevalent wireworm species studied was <i>Agriotes sordidus</i>. Both sets of trials showed that some 4x-breeding clones were tolerant to wireworm attacks. …”
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10731
Teak-Soil Interaction: Teak (Tectona grandis) Plantations Impact and are Impacted by Soil Properties and Fertility in Southwestern Ghana
Published 2024-01-01“…Teak (Tectona grandis) is one of the most widely established plantation species globally due to its potential for degraded forest restoration, timber supplementation, and easing pressure on natural forest resources. …”
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10732
BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA
Published 2024-03-01“…The prevalence of Gram-negative bacteria species most frequently from Escherichia coli (ESBL) 13.79% (4/29), Klebsiella pneumoniae 10.35% (3/29), Proteus mirabilis 10.35% (3/29). …”
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10733
INTRASPECIFIC VARIABILITY OF THE Sus1 SUCROSE SYNTHASE GENE IN Pisum sativum ACCESSIONS
Published 2018-03-01“…It was also proposed that the sucrose synthase family genes had diverged before legumes split into species.…”
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10734
Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy
Published 2025-01-01“…Abstract In this study, the in vitro photodynamic therapy (PDT) activity of two zinc phthalocyanines (ZnPc1 and ZnPc2) was systematically examined in human umbilical vein endothelial cells, focusing on PDT-induced cytotoxicity, reactive oxygen species (ROS) generation, and inhibition of angiogenic processes. …”
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10735
An observation-based method to estimate carbonate system variations in the Labrador Sea
Published 2025-01-01“…With the core carbonate variables estimated, other aspects of the carbonate system are calculated using CO2SYS, such as the aragonite and calcite saturation states, the Revelle factor, and the carbonate species. Our method also calculates uncertainties that vary over time and depth based on the availability of observations and their variance, which has lowered the uncertainty for pH by 71% and for fCO2 by 64% compared to time-independent methods.…”
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10736
Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode
Published 2021-01-01“…Based on these lines of molecular evidence, we discussed whether these different binding modes are species- or crystallography-dependent.…”
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10737
<i>In vitro</i> clonal micropropagation of selected <i>Malus niedzwetzkyana</i> Dieck forms demonstrating high resilience when introduced into urban environments
Published 2024-10-01“…They served as source material for the development of a clonal propagation protocol and in vitro preservation of selected genotypes of this species. Results. It was shown for M. niedzwetzkyana that the most favorable time for taking its plant material for introduction into in vitro culture is the beginning of the active growth of vegetative shoots after flowering. …”
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10738
Closing the phenotyping gap with non-invasive belowground field phenotyping
Published 2025-01-01“…This paper investigates whether electrical resistivity tomography (ERT) provides sufficient precision and accuracy to distinguish between belowground plant traits of different genotypes of the same crop species. The proof-of-concept experiment was conducted in 2023, with three distinct soybean genotypes known for their contrasting reactions to drought stress. …”
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10739
CooccurrenceAffinity: An R package for computing a novel metric of affinity in co-occurrence data that corrects for pervasive errors in traditional indices.
Published 2025-01-01“…We provide functions to perform the analysis based on a 2×2 contingency table of occurrence/co-occurrence counts as well as a m×n presence-absence matrix (e.g., species by site matrix). The flexibility of the function allows a user to compute the alpha MLE for entity pairs on matrix columns based on presence-absence states recorded in the matrix rows, or for entity pairs on matrix rows based on presence-absence recorded in columns. …”
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10740
Evaluating the Effect of Artemisia Aerial Parts Extracts on Candida albicans growth and Shear Bond Strength of Soft Denture Liner
Published 2021-06-01“…The objective of this study was to evaluate the effect of oil and ethanol extracts of Artemisia aerial parts on Candida albicans growth and shear bond strength of soft denture liner. Candida albicans species were isolated and diagnosed, oil and ethanol extracts of Artemisia were prepared, the effect of the extracts on Candida albicans were tested by agar well diffusion test and micro dilution test. …”
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