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10461
Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa
Published 2025-02-01“…These trials were conducted on a range of net products with different AIs, across a range of geographies in Africa (East and West), vector species (Anopheles gambiae, Anopheles coluzzii, Anopheles arabiensis, and Anopheles funestus), hut designs (East and West African style) and hosts (cows and humans). …”
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10462
FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms
Published 2025-03-01“…In cardiomyocytes, restoration of FNDC5 expression was sufficient to mitigate reactive oxygen species (ROS) accumulation and apoptosis following doxorubicin exposure, effects dependent on the irisin encoding domain of FNDC5 as well as signaling via the putative irisin integrin receptor. …”
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10463
A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei
Published 2025-01-01“…This primer set did not detect any other Burkholderia species. Using this novel primer set, a dried-format in-house LAMP method with high sensitivity and specificity was developed. …”
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10464
Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes
Published 2025-01-01“…HG stimulation impaired EDRs in mouse aortas and inhibited nitric oxide (NO) production but elevated reactive oxygen species (ROS) levels in RAECs. CA reversed these impairments. …”
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10465
Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis)
Published 2025-01-01“…Despite the critical role of buffaloes as livestock and their significance in disease transmission, the Ig loci of this species have not been thoroughly annotated. This study aimed to systematically characterize the Ig loci in buffaloes and their unique features, providing a foundation for understanding buffalo immune function.MethodsThe genomic assembly of Murrah buffalo (NDDB_SH_1) was analyzed to annotate Ig loci. …”
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10466
Kinetic and Photochemical Disequilibrium in the Potentially Carbon-rich Atmosphere of the Warm Jupiter WASP-69 b
Published 2025-01-01“…This study investigates the impact of vertical diffusion and photochemistry on its atmospheric composition, with a focus on the detected species plus HCN and CO _2 , to constrain the atmospheric C/O ratio. …”
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10467
Superior liver protection in mice fed total parenteral nutrition containing the novel lipid emulsion Vegaven as compared to a mixed-oil lipid emulsion containing fish oil
Published 2025-04-01“…Profiling of hepatic lipid mediators revealed the presence of α-linolenic acid-derived hydroxy-octadecatrienoic acid species exclusively in VEGA. Conclusions: TPN with Vegaven provides superior liver protection and whole-body blood glucose control than TPN with mixed-oil lipid emulsion containing fish oil in mice.…”
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10468
Seroprevalence of brucellosis in camels and humans in the Al-Qassim region of Saudi Arabia and its implications for public health
Published 2025-02-01“…Although camels are classified as secondary hosts for Brucella species, they are among the most susceptible and vulnerable animals to brucellosis, particularly Brucella abortus (B. abortus) and Brucella melitensis (B. melitensis). …”
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10469
Seasonal distribution and cercarial shedding of Bulinus spp. snails: Implications for urogenital schistosomiasis control in the Simiyu Region, northwestern Tanzania
Published 2025-01-01“…Urogenital schistosomiasis is a neglected tropical disease of significant public health concern caused by the trematode species Schistosoma haematobium. Its transmission is localised and heterogeneous, with seasonal occurrences in Tanzania primarily facilitated by Bulinus spp. snails, which serve as intermediate hosts. …”
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10470
Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU
Published 2020-01-01“…In subgroup analysis, serum levels of ApoA5 were significantly correlated with sepsis-associated multiple organ dysfunction syndrome (MODS) (P<0.001), shock (P=0.002), acute kidney injury (AKI) (P<0.001), acute liver injury (ALI) (P=0.002), and gastrointestinal (GI) dysfunction (P=0.012), but not respiratory failure, brain injury, and pathogenic species (all P>0.05). Correlation analyses revealed significant correlations of serum ApoA5 with Ca2+ concentration. …”
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10471
Differential responses of soil C, N, and P ecological stoichiometric characteristics to different configurations of edge-locked forests in the Kubuqi Desert
Published 2025-01-01“…In conclusion, SZ and SL can be used as the dominant tree species in the edge-locked forests of the Kubuqi Desert, and the NT + XYY mixed forest configuration pattern displays the most apparent soil improvement effect. …”
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10472
Habitat suitability modeling for Posidonia oceanica distribution along a Mediterranean region (NW Italy)
Published 2025-02-01“…Delile is a keystone seagrass species, playing a central role in the ecological balance of Mediterranean coastal areas but threatened by increasing human pressures. …”
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10473
Biological Characteristics and Whole-Genome Analysis of a Porcine <i>E. coli</i> Phage
Published 2025-01-01“…Psq-1 only lyses the host bacterium and does not affect other <i>E. coli</i> strains or other species of bacteria. The optimal MOI for phage Psq-1 was 0.1, with a latent period of 25 min, an exponential growth period of 25 min, and a lysis yield of 44.21 PFU/cell. …”
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10474
Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse
Published 2025-01-01“…In mice, PE exposure significantly reduced the number of retrieved oocytes (31.5 vs. 36.3, P < 0.05) and fertilization rate (70.8 % vs. 85.2 %, P < 0.001), while increasing the proportion of poor-quality oocytes (28.2 % vs. 16.5 %, P < 0.001) and reactive oxygen species (ROS) production compared to controls. RNA sequencing indicated significant upregulation of inflammation-related genes (Il10ra, Il1a, Il33, Tnfaip8l2, and Tnfrsf1b) in the PE-exposed group. …”
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10475
Incorporation of reduced glutathione to the extender improves frozen-thawed sperm function and fertility potential in mandarin fish (Siniperca chuatsi)
Published 2025-03-01“…Semen cryopreservation is a valuable tool for assisted reproduction in aquatic species. Despite the various advantages in hatchery practices, damage occurred during the process of freezing and thawing can result in compromised sperm quality. …”
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10476
A lignin-based controlled/sustained release hydrogel by integrating mechanical strengthening and bioactivities of lignin
Published 2025-02-01“…Also, the developed hydrogel had good biocompatibility and the released lignin had reactive oxygen species scavenging as well as inhibitory activity against Staphylococcus aureus. …”
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10477
Unveiling the nutraceutical potential of indigenous and exotic eggplant for bioactive compounds and antioxidant activity as well as its suitability to the nutraceutical industry
Published 2025-02-01“…Furthermore, the wild species S. insanum, S. khasianum, and S. xanthocarpum can also be utilized as a donor line for carrying out the nutritional breeding program as they are the reservoir of many important biochemical genes.…”
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10478
Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation
Published 2025-01-01“…This included pathological morphology and lipid deposition analysis of mouse aorta, serum lipid level analysis, Elisa analysis, oxidative stress analysis, reactive oxygen species (ROS) fluorescence assay, immunohistochemical analysis and protein blot analysis. …”
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10479
Inhibition of the invasive plant Ambrosia trifida by Sigesbeckia glabrescens extracts
Published 2025-01-01“…In addition, increases in H2O2 content and respiratory burst oxidase homologue (RbohD) gene expression suggested that A. trifida underwent oxidative stress caused by reactive oxygen species (ROS) bursts, resulting in apoptosis due to the significant upregulation of key genes associated with apoptotic pathways. …”
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10480
Positively charged polysilsesquioxane/iodide lonic liquid as a quasi solid-state redox electrolyte for dye-sensitized photo electrochemical cells: infrared, <mml:math alttext="$^{{...
Published 2006-01-01“…Results of the time-dependent spectra analyses showed the formation of positively charged polyhedral cube-like silsesquioxane species that still contained a small amount of silanol end groups, which were removed after heating at <mml:math alttext="$200un{^{circ} C}$"> <mml:mrow> <mml:mn>200</mml:mn><mml:msup> <mml:mtext></mml:mtext> <mml:mo>°</mml:mo> </mml:msup> <mml:mtext>C</mml:mtext> </mml:mrow> </mml:math>. …”
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