Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development by Monique Evelyn Ueberall, Martina Berchthold, Cécile Häberli, Sven Lindemann, Thomas Spangenberg, Jennifer Keiser, Christoph G. Grevelding

“…Abstract Background Schistosomiasis, which is caused by the parasite Schistosoma mansoni as well as other species of the trematode genus Schistosoma, leads to chronic inflammation and finally to liver fibrosis. …”
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Effect of diet containing alfalfa (Medicago sativa) powder and leaf extract on hemolymph factors of western whiteleg shrimp (Litopenaeus vannamei) under low salinity stress by Kobra Babanejad Abkenar, Arash Akbarzadeh, Ahmad Noori, Mohammad Niroomand

“…ntroduction: The western whiteleg shrimp, Litopenaeus vannamei, is a euryhaline species, but fluctuated salinity can lead to stress. …”
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Levying evidence of the impact of Triphala in the mildly constipated human colon microbiota by Elizabeth Goya-Jorge, Pauline Bondue, Irma Gonza, Samiha Boutaleb, Caroline Douny, Marie-Louise Scippo, Joël Pincemail, Patrice Chiap, Jeoffrey Christyn de Ribaucourt, Fabienne Crahay, Véronique Delcenserie

“…Metabolic profiling of Triphala treatment showed increased phenolic species and antioxidant potential and reduced ammonia, valeric, isovaleric, and isobutyric acids during fermentation, potentially benefiting intestinal health, especially in contexts of constipation. …”
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Gibberellin-3 induced dormancy and suppression of flower bud formation in pitaya (Hylocereus polyrhizus) by Kamran Shah, Xiaoyue Zhu, Tiantian Zhang, Jiayi Chen, Jiaxuan Chen, Yonghua Qin

“…Our findings reveal that GA3 application induces significant bud dormancy and suppresses FB formation, highlighting GA3’s role in modulating flowering in this species. Results GA3 application during peak flowering period significantly altered hormone levels, reducing auxin (AUX), cytokinin (CTK) active forms dihydrozeatin riboside (dhZR), zeatin riboside (ZR), N6-isopentenyladenosine (iPA), and brassinosteroid (BR), while increasing jasmonic acid (JA), GA3, and gibberellin-4 (GA4) levels, with abscisic acid (ABA) levels remaining unchanged compared to control. …”
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Metabolomic profiles of <i>Ribes nigrum</i> L. and <i>Lonicera caerulea</i> L. from the collection of the N.I. Vavilov Institute in the setting of Northwest Russia by T. V. Shelenga, V. S. Popov, A. V. Konarev, N. G. Tikhonova, O. A. Tikhonova, Y. A. Kerv, A. E. Smolenskaya, L. L. Malyshev

“…Because the direction of use depends on the biochemical properties of fruits, which are determined not only by species and varietal characteristics, but also by reproduction conditions, the study of the biochemical composition of fruits grown in various regions of the world continues to be relevant. …”
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Transgressive hybrids as hopeful holobionts by Benjamin Thomas Camper, Andrew Stephen Kanes, Zachary Tyler Laughlin, Riley Tate Manuel, Sharon Anne Bewick

“…Specifically, we test the hypothesis that hybrid lizards have host-associated (HA) microbiota traits strongly differentiated from their progenitor species. Across numerous hybrid microbiota phenotypes, we find widespread evidence of transgressive segregation. …”
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Antioxidant and cytotoxic activities of 2-oxo-1,2,3,4-tetrahydropyrimidines by Sarosh Iqbal, Shahida Perveen, M. Iqbal Choudhary, Musarrat Jabeen, Shumaila Kiran, Faiza Qayyum, Khalid Mohammed Khan

“…Oxidative stress (OS) is an imbalance between ROS and antioxidants which is caused by increased synthesis and buildup of reactive oxygen species as well as a reduced ability to detoxify them. …”
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Studies on the treatment of anaerobically digested sludge by white-rot fungi: evaluation of the effect of Phanerochaete chrysosporium and Trametes versicolor by Xuefeng Zhu, Shicai Cheng, Zexian Fang, Guangyin Zhen, Xueqin Lu, Hongbo Liu, Jing Qi, Zhen Zhou, Xuedong Zhang, Zhichao Wu

“…Microbial community analysis demonstrated that Phanerochaete chrysosporium was the predominant fungal species, exerting a significant regulatory role within the sludge ecosystem. …”
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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

“…Our results suggest that actin-based motility effectors RickA and Sca2 drive two distinct forms of cell-to-cell spread and contribute differently to pathogenicity in the mammalian host.IMPORTANCERickettsia parkeri, a bacterium in the spotted fever group of Rickettsia species, can be transmitted from ticks to humans, leading to symptoms including fever, rash, muscle aches, and a lesion at the site of the tick bite. …”
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Network meta-analysis of cadmium toxicity against Chlorella vulgaris and the role of growth stimulants and macronutrients by M. Iqhrammullah, S. Saudah, M. Monalisa, F. Fahrurrozi, S.A. Akbar, S.S. Lubis

“…Among the various microalgae species, Chlorella vulgaris stands out as a suitable candidate due to its potential for biodiesel production and its capacity to effectively absorb cadmium. …”
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Gellan Gum Enhances the Quality of Egg-Based Yoghurt by Changing the Water Phase Distribution and Improving the Gel Texture by Yuanyuan Zhang, Jianwei Zang, Shutong Liu, Bingxu Yan, Daobang Tang, Jiguang Chen, Dongwen Li, Dayong Peng, Zebo Liu, Zhongping Yin

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Glasswort as a Strategic Crop in Coastal Wetlands: Intercropping Results with Swiss Chard by Anna Rita Bernadette Cammerino, Michela Ingaramo, Vincenzo Rizzi, Maurizio Gioiosa, Massimo Monteleone

“…The use of halophytes as intercropping species to mitigate the effects of salt stress is attractive. …”
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Deciphering the pseudouridine nucleobase modification in human diseases: From molecular mechanisms to clinical perspectives by Shiheng Jia, Xue Yu, Na Deng, Chen Zheng, Mingguang Ju, Fanglin Wang, Yixiao Zhang, Ziming Gao, Yanshu Li, Heng Zhou, Kai Li

“…Abstract RNA pseudouridylation, a dynamic and reversible post‐transcriptional modification found in diverse RNA species, is crucial for various biological processes, including tRNA homeostasis, tRNA transport, translation initiation regulation, pre‐mRNA splicing, enhancement of mRNA translation, and translational fidelity. …”
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Research Note: Establishment of vector system harboring duck RNA polymerase I promoter for avian influenza virus by Yunyueng Jang, Yoon-Gi Baek, Yu-Na Lee, Ra Mi Cha, Yun-Chan Choi, Min-Ji Park, Youn-Jeong Lee, Eun-Kyoung Lee

“…However, the efficiency of RG systems for avian-origin influenza viruses may be compromised due to potential species-specific interactions of RNA pol I. In this study, we reported the polymerase activities of the duck RNA pol I promoter in avian cells and the generation of recombinant avian-derived influenza viruses using a novel vector system containing the duck RNA pol I promoter region to enhance the rescue efficiency of the RG system in avian cells. …”
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The Exocyst Subunits EqSec5 and EqSec6 Promote Powdery Mildew Fungus Growth and Pathogenicity by Jinyao Yin, Xuehuan Zhu, Yalong Chen, Yanyang Lv, Jiaxin Shan, Yuhan Liu, Wenbo Liu, Weiguo Miao, Xiao Li

“…The silenced strains also induced the host defense response including reactive oxygen species accumulation and callose deposition. The silencing of <i>EqSec5</i> or <i>EqSec6</i> also inhibited the secretion of the effector protein EqIsc1, interrupting plant salicylic acid biosynthesis. …”
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Characteristics of Soil Active Carbon Fractions and Carbon Pool Stability in Major Forest Types in Northern Daxing’an Mountains by LIU Beibei, CAI Tijiu

“…[Conclusion] This study helps to improve the understanding of soil active carbon and organic carbon pools in cold temperate forests, artificially promoting secondary forest succession or introducing coniferous species as soon as possible is suggested to form mixed forests in the region, but the role played by broad-leaved forests in soil carbon pools should not be ignored in the context of increasing global warming.…”
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Alloplasmic recombinant lines (H. vulgare)-T. aestivum with 1RS.1BL translocation: initial genotypes for production of common wheat varieties by L. A. Pershina, L. I. Belova, N. V. Trubacheeva, T. S. Osadсhaya, V. K. Shumny, I. A. Belan, L. P. Rosseeva, V. V. Nemchenko, S. N. Abakumov

“…Alloplasmic lines are formed when the cytoplasm of one species is replaced by the cytoplasm of another as a result of repeated recurrent crosses of wide hybrids with the paternal genotype. …”
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Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris) by Sarin Suwanpakdee, Anuwat Wiratsudakul, Nattarun Chaisilp, Luxsana Prasittichai, Anurux Skulpong, Patarapol Maneeorn, Benjaporn Bhusri, Chalisa Mongkolpan, Ruangrat Buddhirongawatr, Jarupa Taowan, Peerawat Wongluechai, Nlin Arya, Parin Suwannaprapha, Natharin Ngamwongsatit, Witthawat Wiriyarat, Nareerat Sangkachai

“…Abstract The canine distemper virus (CDV) could infect various wildlife species worldwide. The viral infection in large felids directly impacts wildlife conservation. …”
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Ammonifying and phosphorus-solubilizing function of Aliikangiella maris sp. nov. isolated from Phaeocystis globosa bloom and algal–bacterial interactions by Fei Li, Fei Li, Ming-Ben Xu, Liang-Hao Pan, Jie Li, Cai-Bi Lan, Zhe Li, Shan Lu, Jun-Xiang Lai, Jun-Xiang Lai, Peng-Fu Li

“…According to phenotypic, chemotaxonomic, phylogenomic, and comparative genomic analyses data, strains GXAS 306T and GXAS 311 were considered to represent a novel species of the genus Aliikangiella. Genomic analysis revealed that strain GXAS 306T had many potential functions favorable for interacting with algae, and further experimental evidence confirmed the ammonifying and phosphorus-solubilizing function. …”
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The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV by Qing Xiao, Fengting Yu, Liting Yan, Xiaojie Lao, Xuelei Liang, Hongxin Zhao, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yao Liu, Fujie Zhang

“…However, the ELR group had a larger proportion of T cells with lipid peroxidation, mitochondrial lipid reactive oxygen species (ROS), and mitochondrial membrane potential (MMP) abnormalities compared to the other groups. …”
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