Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…To address this gap, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) was employed to investigate the age-dependent expression profiles of the A-series ganglioside species GD1a, GM1, GM2, and GM3 in the APP/PS1 transgenic mouse model of AD in which age-dependent amyloid-beta (Aβ) plaques develop. …”
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Guillain-Barré syndrome following falciparum malaria infection: a case report by Molla Asnake Kebede, Alemayehu Beharu Tekle, Misikir Alemu Eshetu, Erkyehun Pawlos Shash, Melaku Tsediew Berhanu, Elias Tabiet Ahmed, Hashime Meketa Negatie

“…Abstract Background Malaria is an infectious disease caused by Plasmodium parasites, transmitted to humans by infected female Anopheles mosquitoes. Five Plasmodium species infect humans: P. vivax, P. falciparum, P. ovale, P. malariae, and P. knowlesi. …”
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GV1001, hTERT Peptide Fragment, Prevents Doxorubicin-Induced Endothelial-to-Mesenchymal Transition in Human Endothelial Cells and Atherosclerosis in Mice by Wei Chen, Seojin Kim, Sharon Y. Kim, Cheyenne Beheshtian, Naryung Kim, Ki-Hyuk Shin, Reuben H. Kim, Sangjae Kim, No-Hee Park

“…By mitigating mitochondrial damage, GV1001 reduced the accumulation of mitochondrial and cellular reactive oxygen species (ROS), repressed the activation of nuclear factor kappa B (NF-κB), and reduced the production of proinflammatory cytokines in endothelial cells. …”
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Ferroptosis: A novel cell death modality as a synergistic therapeutic strategy with photodynamic therapy by Yuqing Wang, Yiting Xu, Yong Qu, Yifang Jin, Juanmei Cao, Jinshan Zhan, Zhuoxia Li, Chuxing Chai, Changzheng Huang, Min Li

“…Ferroptosis, an iron-dependent type of programmed cell death characterized by accumulation of reactive oxygen species and lipid peroxidation products to lethal levels, has emerged as an attractive target trigger for tumor therapies. …”
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Transcriptome Sequencing Reveals Regulatory Mechanisms of Taxol Synthesis in Taxus wallichiana var. Mairei by Tao Wang, Yiming Chen, Weibing Zhuang, Fengjiao Zhang, Xiaochun Shu, Zhong Wang, Qing Yang

“…Taxol is one of the most potent and effective anticancer drugs and is originally isolated from Taxus species. To investigate the specific regulatory mechanisms of taxol synthesis in Taxus wallichiana var. mairei, RNA-seq was conducted to reveal the differences in transcriptional levels between wild type (WT) and “Jinxishan” (JXS), a cultivar selected from a population of Taxus mairei that shows about 3-fold higher taxol content in the needles than WT. …”
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Bio-Recycling Hazelnut Shells to Improve Antioxidant Properties of <i>Lentinus tigrinus</i> Sporophore by Anthea Desiderio, Mariana C. Pedrosa, Sandrina A. Heleno, Marcio Carocho, Daniele B. Rodrigues, Simone Buratti, Irene Soffientini, Daniela Ratto, Elena Savino, Paola Rossi

“…Biological analyses demonstrated that the Lt1_HS extract has higher anti-peroxidant activity (IC₅₀ 0.77 ± 0.01 mg/mL) compared to Lt1_S (IC₅₀ 1.36 ± 0.01 mg/mL) and reduces the accumulation of reactive oxygen species in HaCaT cells by 80%. However, the specific bioactive compounds responsible for these antioxidant effects are still unclear, and further analysis will be conducted. …”
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The presence of iteroparous salmonid spawning grounds affects the stable isotope signatures of food web components in Swedish boreal streams by Rahmat Naddafi, Magnus Enbom, Carin Magnhagen, Nazila Hajizadeh Koupayh, Daniel Holmqvist, Hans Lundqvist

“…Two sites (MDN sites) had spawning Atlantic salmon and sea trout and two other sites (reference sites) had no spawning or mortality areas of these species. A generalized linear mixed model revealed that site type and food web component had a significant effect on δ15N and δ13C values. …”
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Improving Fast‐Charging Performance of Lithium‐Ion Batteries through Electrode–Electrolyte Interfacial Engineering by Seungwon Kim, Sewon Park, Minjee Kim, Yoonhan Cho, Gumin Kang, Sunghyun Ko, Daebong Yoon, Seungbum Hong, Nam‐Soon Choi

“…The conventional additive vinyl carbonate (VC) generates spatially dense and rigid poly VC species that may not ensure fast Li+ transport across the SEI on the anode. …”
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Using benthos a bioindicator to assess the efficiency constructed wetland community wastewater treatment system by K. Seethong, K. Chunkao, N. Dampin, W. Wararam

“…This study assesses the diversity, species composition, and distribution of benthic organisms in a community wastewater-filter grass system and explores the relationship between water quality and benthos.METHODS: Water samples were collected from plant plots between December 2021 and March 2022. …”
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Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway by Jincan Chen, Jie Wang, Yuanyuan Deng, Tao Wang, Tifang Miao, Chengpeng Li, Xianhong Cai, Ying Liu, Justin Henri, Lanmei Chen

“…Further studies revealed that these complexes could induce apoptosis in A549 cells, including activating caspase family proteins and poly (ADP-ribose) polymerase (PARP), reducing Bcl-2/Bax and Bcl-xl/Bad ratio, enhancing cellular reactive oxygen species (ROS) accumulation, triggering DNA damage, decreasing mitochondrial membrane potential (MMP), and leading cytochrome c release from mitochondria. …”
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Tracking pygmy blue whale diving behaviour and validation of foraging areas defined from horizontal movement data by Michele Thums, Luciana C. Ferreira, Andrew Davenport, Micheline Jenner, Luciana Möller, Grace Russell, Robert D. McCauley, Curt Jenner

“…Foraging/feeding occurred every 1–10 days at a rate of 4 hours (median) per day (range 0.1 – 12) and occurred during migration, providing support for use of a mixed breeding strategy (income and capital) in this sub-species. Our test of movement models to define foraging is extremely useful given its common usage in ecology and our spatial delineation of foraging areas assists with conservation management.…”
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Phytochemical Screening and Cytotoxic Properties of Ethanolic Extract of Young and Mature Khat Leaves by Rashad Alsanosy, Hassan A. Alhazmi, Shahnaz Sultana, Ashraf N. Abdalla, Yassin Ibrahim, Mohammed Al Bratty, David Banji, Ibrahim Khardali, Asaad Khalid

“…Catha abbottii, Catha edulis, and Catha transvaalensis are the three species of khat commonly chewed in Saudi Arabia and nearby regions. …”
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ASMENS TAPATUMAS by Alphonso Lingis

“…PERSONAL IDENTITY Alphonso Lingis "Human dignity" - the expression seems to assert some kind of superiority of the human over other species of animals - an assertion biologically unjustifiable and ecologically suspect. …”
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Coexistence of multiple leaf nutrient resorption strategies in urban forests by Pin Li, Zejin Wang, Kun Ran

“…In this study, leaf samples were collected from 15 common tree species from forest patches in eight parks along urban-rural gradients in the Beijing metropolitan region of China. …”
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Biochemical, ecological and molecular characterization of Xenorhabdus anantnagensis associated with Steinernema anantnagense from India: evaluating nematode efficacy against Helico... by Krishnapriya Okram, Aashaq Hussain Bhat, Ladoi Drema

“…Biochemical tests further supported this identification, distinguishing KP_CU from other Xenorhabdus species based on citrate utilization, gelatinase, lysine decarboxylase, urease, arginine dihydrolase, ornithine decarboxylase, glucose oxidation, cytochrome oxidase and indole production. …”
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Preparation, characterization of mixed-valence antimony-tin phosphomolybdic polyoxometalates and application in the cyclohexanone oxidation in the presence of hydrogen peroxide by Maiouf, Fatma-Zohra, Boumechhour, Abdenour, Benadji, Siham, Dermeche, Leila, Mazari, Tassadit, Lancelot, Christine, Rabia, Chérifa

“…The reversible cyclic voltammetry analysis evidenced the valence change of the Mo species, Mo(VI)/Mo(V). The POMs are found to be active in the cyclohexanone oxidation reaction and among them the most efficient is $\mathrm{H}_{0.75}\mathrm{Sb}_{0.75}\mathrm{PMo}_{12}\mathrm{O}_{40}$ with 49% of adipic acid yield.…”
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Pseudomonas cold shock proteins suppress bacterial effector translocation in Nicotiana benthamiana by Shen Cong, Jun-Zhou Li, Mei-Ran Zhang, Mei-Ran Zhang, Hai-Lei Wei, Wei Zhang

“…Transient expression of these CSPs neither induced reactive oxygen species (ROS) production nor suppressed the hypersensitive response (HR) in N. benthamiana, however, it restricted bacterial effector translocation. …”
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Sources of PM2.5 exposure and health benefits of clean air actions in Shanghai by Yixuan Gu, Daven K. Henze, Hong Liao

“…By incorporating high-resolution satellited-derived PM2.5 estimates into the calculation, we investigate the response of PM2.5 exposure and its related health impacts in Shanghai to changes in anthropogenic emissions from each individual region, species, sector, and month. We estimate that a 10% decrease in anthropogenic emissions throughout China avoids over 752 (506–1,044) PM2.5-related premature deaths in Shanghai, with changes in local emissions potentially saving 241 (161–334) lives. …”
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Assessment of farmers' knowledge, attitudes and control practices (KAP) to mitigate acaricide resistance and tick-borne diseases by Sunita Jamra, Mukesh Shakya, Anant K. Jayraw, Vivek Agrawal, Mamta Singh, Anil Kumar Sharma, Gajendra N. Bhangale, Gaya P. Jatav, Nirmala Jamra, Ala Tabor

“…Resistance status of collected tick isolates of Rhipicephalus microplus and Hyalomma anatolicum was assessed and revealed that both tick species were found resistant to deltamethrin. The goals of this study were to assess some of the underlying causes of ticks and TBD in livestock in Dhar district of Madhya Pradesh state using the KAP survey and resistance characterization of ticks.…”
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Near telomere-to-telomere genome assemblies of Silkie Gallus gallus and Mallard Anas platyrhynchos restored the structure of chromosomes and “missing” genes in birds by Qiangsen Zhao, Zhongtao Yin, Zhuocheng Hou

“…Recent pangenome studies suggest that a single genome is insufficient to represent the genetic information of a species, highlighting the need for more comprehensive genomes. …”
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