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10001
Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb
Published 2025-01-01“…Here, based on the concept of creating a “mobile barrier”, we develop an anti-Mb rabbit monoclonal antibody (RabMAb) with high specificity, affinity, stability, and broad species reactivity. A single dose of anti-Mb RabMAb injection is sufficient for emergency rescue in both homologous and heterologous RM/CS-AKI male animal models. …”
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10002
A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria
Published 2025-01-01“…The dataset contains a total of 11,055 spectra from altogether 1,601 microbial strains and 264 species and is primarily intended to improve the diagnosis of HPB. …”
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10003
Plant Adaptation and Soil Shear Strength: Unraveling the Drought Legacy in <i>Amorpha fruticosa</i>
Published 2025-01-01“…Focusing on <i>Amorpha fruticosa</i>, a species known for its robust root system that plays a crucial role in soil consolidation and slope stabilization, thereby reducing soil and water erosion, we simulated a drought-rewetting event to assess the legacy effects of drought on the soil shear strength and the mechanical and hydrological traits associated with the reinforcement provided by <i>A. fruticosa</i>. …”
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10004
Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism
Published 2025-01-01“…We demonstrated that L. reuteri is a fundamental species responsible for modulating lipid deposition in NX pigs and that increased circulating levels of BCAA are positively linked to greater lipid deposition. …”
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10005
A supervised model to identify wolf behavior from tri-axial acceleration
Published 2025-01-01“…Such models typically need to be trained on data from the target species. The present study focuses on developing a behavioral classification model tailored to the grey wolf (Canis lupus) and encompassing a variety of ecologically relevant behaviors. …”
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10006
Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds
Published 2018-01-01“…In conclusion, a cell-based high-throughput screening assay was developed for the discovery of porcine HDP inducers, and newly identified HDP-inducing compounds may have potential to be developed as alternatives to antibiotics for applications in swine and possibly other animal species.…”
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10007
Simultaneous exposure to microplastics and heavy metal lead induces oxidative stress, histopathological damage, and immune dysfunction in marine mussel Mytilus coruscus
Published 2025-01-01“…Meanwhile, co-exposure poses a significant threat to the immune function of the mussels, as evidenced by induction of hemocytes to produce excess reactive oxygen species (ROS), significantly reducing lysosome activity (p < 0.05), inhibiting the expression of autophagy-related genes, and inducing the expression of apoptosis-related genes, resulting in hemocyte apoptosis. …”
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10008
Dietary addition of compound organic acids improves the growth performance, carcass trait, and body health of broilers
Published 2025-01-01“…Despite their promising effects in other animal species, the impact of this novel compound organic acidifier on broiler performance, metabolism, and immune response has not been fully elucidated. …”
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10009
A life stage resolved habitat model for guiding seagrass restoration in coastal lagoons
Published 2025-01-01“…The Coorong Lagoon in South Australia faces significant threats from reduced freshwater inputs and eutrophication, with the keystone macrophyte species, Ruppia tuberosa, generally in a state of decline. …”
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10010
Reduced Numbers of Returning Atlantic Salmon (<i>Salmo salar</i>) and Thiamine Deficiency Are Both Associated with the Consumption of High-Lipid Prey Fish
Published 2024-12-01“…We investigated how the numbers of age-0 and young herring (<i>Clupea harengus</i>) and sprat (<i>Sprattus sprattus</i>), which are the principal prey species of salmon in the Baltic Proper, the main feeding area of these salmon, as well as the amount of lipid obtained from them and their protein-to-lipid ratio, correlated with the number of returning salmon and the thiamine (vitamin B1) status of spawning salmon. …”
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10011
Intraparenchymal Neural Stem/Progenitor Cell Transplantation for Ischemic Stroke Animals: A Meta-Analysis and Systematic Review
Published 2018-01-01“…With further analysis, it was found that the administration time poststroke, NSPC donor species, and transplantation immunogenicity had close correlations with the degree of infarct volume reduction. …”
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10012
Diversity of Picea omorika (Pančić) Purk. Populations Based on Morpho-anatomical Needle Traits and Bioclimatic Parameters
Published 2024-01-01“…Picea omorika (Pančić) Purkyne is a well-known endemic conifer species. However, there have been few morpho-anatomical studies to date. …”
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10013
Exogenous dsRNA triggers sequence-specific RNAi and fungal stress responses to control Magnaporthe oryzae in Brachypodium distachyon
Published 2025-01-01“…Leaf application of dsRNA to the cereal model species Brachypodium distachyon suppressed the progression of leaf blast disease. …”
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10014
Advancing the Indian cattle pangenome: characterizing non-reference sequences in Bos indicus
Published 2025-02-01“…Additionally, 70.28% of BICIs are shared with other domesticated and wild species, highlighting their evolutionary significance. …”
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10015
Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning...
Published 2025-01-01“…This study was based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), Decision Tree (DT), Random Forest (RF), Gradient Boosting Machine (GBM), eXtreme Gradient Boosting (XGBoost), and Extremely Randomized Trees (ERT) models were constructed to classify carbapenem-resistant Escherichia coli (CREC) and carbapenem-resistant Klebsiella pneumoniae (CRKP). Bacterial species were identified by MALDI-TOF MS in positive blood cultures isolated via the serum isolation gel method, and E. coli and K. pneumoniae in positive blood cultures were collected and placed into machine learning models to predict susceptibility to carbapenems. …”
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10016
Characterization and utilization of trichoderma sp. for efficient management of oil palm empty fruit bunch waste in plantations
Published 2024-10-01“…BACKGROUND AND OBJECTIVES: Trichoderma species (Trichoderma sp.) is commonly found in nature, particularly in soil and roots, often thriving in plants rich in cellulose such as oil palm. …”
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10017
Superoxide dismutase promotes gastric tumorigenesis mediated by Helicobacter pylori and enhances resistance to 5-fluorouracil in gastric cancer
Published 2025-02-01“…Knockdown of SOD2 led to increased levels of reactive oxygen species and oxidative stress in response to H. pylori infection. …”
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10018
FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent man...
Published 2024-12-01“…The viability and apoptosis of PTECs under various conditions, and reactive oxygen species (ROS), superoxide dismutase (SOD), and malonaldehyde (MDA) levels within these cells were measured using commercial assay kits and flow cytometry. …”
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10019
Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice
Published 2025-01-01“…Moreover, COS significantly reduced liver reactive oxygen species (ROS) levels, malondialdehyde (MDA) content, and lactate dehydrogenase (LDH) release in DON-exposed mice, while restoring the activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC). …”
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10020
Lines resistant to downy mildew in the sunflower genetic collection at VIR
Published 2021-10-01“…Lines ТА 716-18, VIR 768 and VIR 800 appeared highly resistant to the pathogen and probably possess new resistance genes/alleles introgressed from wild species.…”
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