ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation by Yuan Chang, Yihua He, Di Wang, Kunxue Zhang, Yuzhen Zhang, Zhentong Li, Shuxin Zeng, Sheng Xiao, Suyue Pan, Kaibin Huang

“…Utilizing the mouse model of RIBI and irradiated BV2 cells, we further demonstrated that irradiation caused mitochondrial damage to microglia, leading to violent release of reactive oxygen species (ROS), which enhanced the transcription of SUR1, TRPM4, and NLRP3 inflammasome-related molecules. …”
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Global demand for rice genetic resources by Nelissa Jamora, Venuprasad Ramaiah

“…Abstract Background The International Rice Research Institute (IRRI) holds in trust the world's largest collection of rice diversity, with more than 130,000 accessions of cultivated rice and wild species. Between 2012 and 2018, a total of 2174 requests for rice germplasm were received from more than 1000 unique requestors. …”
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CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

“…Cell viability, apoptosis, lipid reactive oxygen species (ROS) levels and iron content were determined via Cell Counting Kit-8 (CCK-8) and flow cytometric assays. …”
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A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border. by April T Ansari, Ko Ko Aung, Htun Htun Win, Candy Beau, Be Nu, Nay Lin Soe, Klay Htoo, Thida San, Tha Gay Wah, Arunrot Keereevijit, Aung Pyae Phyo, Kesinee Chotivanich, Nicholas J White, François Nosten, Ahmar H Hashmi, Cindy S Chu

“…Patients of Karen ethnicity (OR 1.7, 95% CI 1.2-2.3; p = 0.001) or having a previous episode of malaria from any species (OR 1.6, 95% CI 1.1-2.3; p = 0.007) were more likely to report completing the 14-day primaquine radical cure regimen. …”
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Sonication: A Valuable Technique for Diagnosis and Treatment of Periprosthetic Joint Infections by D. S. Evangelopoulos, I. P. Stathopoulos, G. P. Morassi, S. Koufos, A. Albarni, P. K. Karampinas, A. Stylianakis, S. Kohl, S. Pneumaticos, J. Vlamis

“…Sixteen of thirty four periprosthetic tissue cultures (47.1%) were considered positive, all revealing the same microbial species with the respective sonication fluid cultures: 3 tissue samples showed polymicrobial infection. …”
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Imbalance of oral microbiome homeostasis: the relationship between microbiota and the occurrence of dental caries by Rui Liu, Yingshuang Liu, Jialong Yi, Yanke Fang, Qiang Guo, Lei Cheng, Jinzhi He, Mingyun Li

“…Acidogenic and aciduric microbial species are also recognized to participate in the initiation and progression of dental caries. …”
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Genome Sequencing Providing Molecular Evidence of Tetrapolar Mating System and Heterothallic Life Cycle for Edible and Medicinal Mushroom <i>Polyporus umbellatus</i> Fr. by Shoujian Li, Youyan Liu, Liu Liu, Bing Li, Shunxing Guo

“…<i>Polyporus umbellatus</i> is a species whose sclerotia have been extensively employed in traditional Chinese medicine, which has diuretic, antitumor, anticancer, and immune system enhancement properties. …”
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Evaluation of synthetic wheat lines (Triticum durum/Aegilops tausсhii) for vegetative period and resistance to diseases by V. P. Shamanin, I. V. Pototskaya, S. S. Shepelev, V. E. Pozherukova, A. Yu. Truschenko, A. S. Chursin, A. I. Morgunov

“…Increase of resistance to stress factors in the emerging varieties can be achieved by utilizing the diversity of the genetic resources of related wild species and genera in crosses. The results of a phenotypic evaluation of the synthetic hexaploid wheat lines of CIMMYT breeding created by crossing durum wheat varieties from Institute of Breeding and Genetics (Odessa, Ukraine) and variety Pandur from Romania (T. durum Desf., AB genome) with Aegilops (Ae. tausshii Coss., D genome), and also 15 synthetic wheat lines of Kyoto University breeding (Japan) created by crossing durum wheat variety Langdon with different ecological forms Aegilops are presented. …”
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Plant Detection in RGB Images from Unmanned Aerial Vehicles Using Segmentation by Deep Learning and an Impact of Model Accuracy on Downstream Analysis by Mikhail V. Kozhekin, Mikhail A. Genaev, Evgenii G. Komyshev, Zakhar A. Zavyalov, Dmitry A. Afonnikov

“…In the present work, a method is presented for detecting the plants of five species in images acquired via a UAV on the basis of image segmentation by deep learning algorithms (convolutional neural networks). …”
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Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring by Federico Sizzano, Sebastiano Collino, Ornella Cominetti, Daniela Monti, Paolo Garagnani, Rita Ostan, Chiara Pirazzini, Maria Giulia Bacalini, Daniela Mari, Giuseppe Passarino, Claudio Franceschi, Alessio Palini

“…The production of reactive oxygen species (ROS) may promote immunosenescence if not counterbalanced by the antioxidant systems. …”
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Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites by Zeng Zhang, Yajing Fang, Yangli He, Mohamed A. Farag, Min Zeng, Yukai Sun, Siqi Peng, Shuaiming Jiang, Xian Zhang, Kaining Chen, Meng Xu, Zhe Han, Jiachao Zhang

“…It reduced pathogenic gut species and increased beneficial metabolites such as indole-3-lactic acid, acetoacetic acid, and creatine. …”
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The Effects of Disinfection Byproduct 2,6-Dichloro-1,4-benzoquinone on the Cyanobacterium <i>Microcystis aeruginosa</i>: From the Perspectives of Biochemistry and Non-Targeted Meta... by Tianqi Zhang, Zhaoyang Wang, Liang Wu, Chaonan Liu, Liang Meng, Fuxiang Tian, Meifang Hou, Haizhuan Lin, Jing Ye

“…The results show that 2,6-DCBQ inhibited the growth of <i>M. aeruginosa</i>, reduced its photosynthetic pigment and protein contents, increased the levels of reactive oxygen species, damaged the antioxidant defense system, and aggravated the cytomembrane. …”
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Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1 by Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry

“…These results suggest that comparing oxidative deamination in mouse and rat VAP-1 may be important if using these species for preclinical efficacy models.…”
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The ethics of theft: Reevaluating the impacts of floral larceny on plant reproductive success by Jin-Ru Zhong, Xiao-Fang Jin, Michael C. Orr, Xiao-Qing Li, Yong-Deng He, Sheng-Wei Wang, Qing-Feng Wang, Chun-Feng Yang, Zhong-Ming Ye

“…We conducted a comprehensive meta-analysis of 153 studies across 120 plant species, using 14 moderators to assess the effects of floral larceny on plant reproductive success and examine the key moderators. …”
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Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress by Giuseppina Palladini, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Stefano Perlini, Andrea Ferrigno, Mariapia Vairetti

“…Gelatinase (MMP-2; MMP-9) activity and protein levels, tissue inhibitors of metalloproteinase (TIMPs), reactive oxygen species (ROS), and thiobarbituric acid-reactive substances (TBARS) were evaluated in the left (LL), median (ML), and right liver (RL) lobes. …”
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Blue light irradiation combined with low-temperature storage further enhances postharvest quality of strawberries through improving antioxidant defense and cell wall metabolic acti... by Wei Lu, Wanqing Li, Keke Zhao, Xiaofeng Bai, Yuchang Zhang, Qingyun Li, Zhanjun Xue, Xin-Xin Wang

“…Additionally, increases of the enzymatic activities of antioxidant defense metabolism (e.g. superoxide dismutase (SOD) and peroxidase (POD)) accompanied with decreased levels of reactive oxygen species (ROS) (e.g. superoxide anion (O2−), and hydrogen peroxide (H2O2)) and the content of secondary metabolites (e.g. ascorbic acid (AsA)) accompanied with enhanced activities of ascorbate peroxidase (APX) and glutathione reductase (GR) were found in BL irradiated postharvest strawberries at the later stages of storage. …”
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Modeling vegetation density with remote sensing, normalized difference vegetation index and biodiversity plants in watershed area by R.Z. Ekaputri, T. Hidayat, H.K. Surtikanti, W. Surakusumah

“…Within the Bengkulu watershed area, a total of 49 tree species from 22 families were identified, with diversity indices falling within the moderate category.CONCLUSION: An in-depth knowledge of the ecological factors and plant preservation initiatives in the Bengkulu watershed can greatly aid in sustainable environmental management and help policymakers develop more effective policies for ensuring environmental sustainability. …”
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Learnings from COVID-19 Forced Lockdown on Regional Air Quality and Mitigation Potential for South Asia by Abhishek Upadhyay, Parth Sarathi Mahapatra, Praveen Kumar Singh, Sishir Dahal, Suresh Pokhrel, Amit Bhujel, Indu Bikram Joshi, Shankar Prasad Paudel, Siva Praveen Puppala, Bhupesh Adhikary

“…Here, we analyze changes in levels of air quality species across the region during selected lockdown periods using satellite and in-situ datasets. …”
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Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…Results: Treatment with the extract contributed to a significant reduction in the release of nitric oxide and reactive oxygen species in the ethanol-treated HepG2 cells; promoted the elevated expression of superoxide dismutase, catalase, and glutathione, indicating enhanced antioxidant defenses; and showed strong free radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl radicals. …”
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Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

“…We used HPLC to detect the main chemical components in HD and, using a UVB-induced photoaging model in HaCaT keratinocytes, examined the effects of HD on reactive oxygen species (ROS) levels, Ca²⁺ concentration, mitochondrial membrane potential (MMP), apoptosis, and the cell cycle. …”
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