Metabolomic approach to investigate <i>Dactylis glomerata</i> L. from the VIR collection by N. Yu. Malysheva, T. V. Shelenga, A. E. Solovyeva, T. B. Nagiev, N. V. Kovaleva, L. L. Malyshev

“…The perennial grass cocksfoot (Dactylis glomerata L.) is a valuable early highly nutritious crop used as green fodder in agricultural production. The species is widespread across the Eurasian continent; it is characterized by plasticity and high ecological and geographical variability. …”
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A hypomorphic mutation in the mouse Csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection by A. V. Smirnov, T. A. Shnaider, A. N. Korablev, A. M. Yunusova, I. A. Serova, N. R. Battulin

“…Sequence variations in the casein genes affect milk composition in livestock species. Regulatory elements of the casein genes could be used to direct the expression of desired transgenes into the milk of transgenic animals. …”
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The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease by Paulina Jakubczyk, Piotr Widera, Justyna Helis, Maciej Michalik, Aleksandra Buczek, Hubert Bigajski, Aleksandra Banaś, Olga Bilczewska, Wiktoria Janik, Marta Handschuh

“…State of Knowledge Moderate-intensity aerobic and resistance exercises reduce systemic inflammatory markers, (CRP and cytokines) and enhance gut microbiota diversity, increasing anti-inflammatory species. Low-to-moderate intensity activities improve quality of life in IBD patients. …”
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Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus by S. N. Shchelkunov, T. V. Bauer, S. N. Yakubitskiy, A. A. Sergeev, A. S. Kabanov, S. A. Pyankov

“…This new situation allows orthopoxviruses to circulate in the human population and, as a consequence, to alter several established concepts of the ecology and range of sensitive hosts for various orthopoxvirus species. Classic VACV-based live vaccine for vaccination against orthopoxvirus infections is out of the question, because it can cause severe side effects. …”
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Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

“…The evolution of such systems is approached by phylogenetic reconciliation, which describes the common patterns of diversification between two different levels, e.g. genes and species, or hosts and symbionts for example. The limit to two levels hides the multi-level inter-dependencies that characterize complex systems. …”
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Understanding Ozone Formation and Carbonyl Contributions in the Seoul Metropolitan Area by Seung-Ha Lee, Ji-Seon Lee, Hyung-Min Lee, Hyeong-Ahn Kwon, Caroline R. Nowlan, Gonzalo González Abad, Rokjin J. Park, Ji-Hoon Park, Soyoung Kang, Hye-Jung Shin, Dai-Gon Kim, Jung-Min Park

“…We calculated the ozone formation potential (OFP) of each VOC species using Maximum Incremental Reactivity (MIR). …”
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The Influence of Monoamine Oxidase Variants on the Risk of Betel Quid-Associated Oral and Pharyngeal Cancer by Ping-Ho Chen, Bin Huang, Tien-Yu Shieh, Yan-Hsiung Wang, Yuk-Kwan Chen, Ju-Hui Wu, Jhen-Hao Huang, Chun-Chia Chen, Ka-Wo Lee

“…The primary alkaloid of AN, arecoline, can be metabolized via the monoamine oxidase (MAO) gene by inducing reactive oxygen species (ROS). The aim of this study was to investigate whether the variants of the susceptible candidate MAO genes are associated with OPMDs and oral and pharyngeal cancer. …”
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Updates on hosts and distribution of pepper yellow leaf curl Indonesia virus and squash leaf curl China virus in Central Java Province, Indonesia by Adyatma Irawan Santosa, Adenisa Hanifah Irbati, Geby Nandita Cahyaning Pratiwi, Antama Surwadinata, Putri Laeshita, Krisnanda Surya Dharma, Reko Saputra Jaya, Annisa Lisa Andriyani, Chilya Qurrota A'yun, Chusnu Naura Syifa Fatika

“…Meanwhile, SLCCNV OR924278 was clustered, and shared 95.8 – 96.7% nt and 98.4 – 99.5% aa identities with three Malaysian isolates (MW248685, MW248687, and MW248689). Different plant species inoculated with SLCCNV OR924278 remained symptomless up to four weeks observation, suggesting that the isolate is not mechanically transmissible. …”
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Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice by Rui-xi Sun, Wei-jun Huang, Yao Xiao, Dou-dou Wang, Guo-hua Mu, He Nan, Bo-ran Ni, Xiao-qiang Huang, Hsuan-chuan Wang, Yi-fan Liu, Qiang Fu, Jin-xi Zhao

“…It could also upregulate the abundance of Bacteroidaceae, which contributed to the metabolism of starch and sucrose as well as pentose-glucuronate interconversions. In the species level, SL decoction significantly upregulates the relative abundance of Bacteroides_acidifaciens which showed a significant negative correlation with FBG and was reported to be a potential agent for modulating metabolic disorders such as diabetes and obesity. …”
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Direct MALDI-TOF MS-based method for rapid identification of microorganisms and antibiotic susceptibility testing in urine specimens by Fouad Assi, Brahim Jabri, Lamia Melalka, Yassine Sekhsokh, Mimoun Zouhdi

“…Results: The direct identification technique accurately identified 92.14% of microorganisms at the genus level and 60.92% at the species level within an hour, significantly faster than the 24 to 48 hours required by traditional culture methods. …”
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Polyp and tumor microenvironment reprogramming in colorectal cancer: insights from mucosal bacteriome and metabolite crosstalk by Hadi Feizi, Hossein Samadi Kafil, Andrey Plotnikov, Vladimir Kataev, Alexander Balkin, Ekaterina Filonchikova, Mohammad Ahangarzadeh Rezaee, Reza Ghotaslou, Mohammad Sadrkabir, Hiva Kadkhoda, Fadhil S. Kamounah, Sergei Nikitin

“…In addition, some bacterial species including Gemella morbillorum, and Morganella morganii were enriched in the AP compared to the H group. …”
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Towards climate-resilient conservation: Integrating genetics and environmental factors in determining adaptive units of a xeric shrub by Yong-Zhi Yang, Pei-Wei Sun, Chong-Yi Ke, Min-Xin Luo, Jui-Tse Chang, Chien-Ti Chao, Run-Hong Gao, Pei-Chun Liao

“…Integrating genomic insights into breeding programs can further enhance the resilience and sustainable management of this vulnerable species.…”
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Synergistic attenuation of complete freund’s adjuvant-induced inflammation in mice using shinbaro-pelubiprofen: a novel therapeutic complex by Hyunseong Kim, Jin Young Hong, Wan-Jin Jeon, Hyun Kim, Changhwan Yeo, Junseon Lee, Yoon Jae Lee, In-Hyuk Ha

“…Results In vitro, SBR-Pel synergistically reduced the production of nitric oxide and reactive oxygen species and the expression of pro-inflammatory cytokines. …”
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Cultures as types and the utility of viable specimens for fungal nomenclature by Andrey Yurkov, Cobus M. Visagie, Pedro W. Crous, Akira Hashimoto, Christiane Baschien, Dominik Begerow, Martin Kemler, Nathan Schoutteten, Marc Stadler, Nalin N. Wijayawardene, Kevin D. Hyde, Ning Zhang, Teun Boekhout, ICTF Yeast Working Group, Tom W. May, Marco Thines, David L. Hawksworth

“…Abstract The debates over the requirement of the International Code of Nomenclature for algae, fungi, and plants (ICNafp) for a viable specimen to represent the name-bearing type material for a species or infraspecific taxon have a long history. …”
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Parthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathway by Jun Zhang, Xing Zhu, Yong Li, Yinyu Wu, Yunxia Du, Hai Yang, Zhengchao Liu, Haoyu Pei, Rui Li, Huan Luo, Deyu Zuo, Han She, Qingxiang Mao

“…PTL treatment also enhances coagulation function, augments vascular endothelial cell (VEC) function, reduces mitochondrial fragmentation, and increases both mitochondrial oxygen consumption rate (OCR) and mitochondrial membrane potential (MMP), while inhibiting reactive oxygen species (ROS) production. By increasing BRD4/BCL-xL levels, PTL can prevent mitochondrial-mediated apoptosis in VECs, improve VEC function, and consequently ameliorate SIC. …”
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Biological control of ticks in domestic environments: Modeling the potential impact of entomopathogenic fungi on the transmission of East Coast fever in cattle by Joseph Wang'ang'a Oundo, Nienke Hartemink, Mart C.M. de Jong, Constantianus J.M. Koenraadt, Shewit Kalayou, Daniel Masiga, Quirine ten Bosch

“…For Metarhizium anisopliae isolate ICIPE 7, one of these EPFs, efficacy against multiple tick species has been demonstrated in laboratory and field settings. …”
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Chemical Composition and Larvicidal Activity of Lavandula angustifolia Subsp. angustifolia and Lavandula dentata Spp. dentata Essential Oils against Culex pipiens Larvae, Vector of... by Fouad El-Akhal, Amal Ramzi, Abdellah Farah, Yassine Ez Zoubi, Moussa Benboubker, Khalid Taghzouti, Abdelhakim El Ouali Lalami

“…These results suggest using essential oils of two species of Lavandula to control the Culex pipiens mosquito. …”
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Emodin Improves Juvenile Largemouth Bass (<i>Micropterus salmoides</i>) Liver Health Through Nrf2/NF-κB Pathway and Fat Metabolism: Growth Performance, Immune Response and Resistan... by Zhenxin Zhao, Fei Zhao, Tianxun Luo, Zhou Zhou, Xianbo Zhang

“…Additionally, EM-1000 could up-regulate the expressions of nuclear factor erythroid 2-associated factor 2 (<i>Nrf2</i>) and heme oxygenase-1 (<i>HO-1</i>) in livers compared with controls and boost antioxidant enzymes activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT), along with a lower content of reactive oxygen species (ROS) and malondialdehyde (MDA). Meanwhile, the EM-1000 group increased anti-inflammatory cytokines of interleukin-10 (<i>IL-10</i>) while suppressing the interleukin-8 (<i>IL-8</i>) expression of pro-inflammatory cytokines in livers by contrast to controls. …”
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Intestinal Parasitic Infections, Treatment and Associated Factors among Pregnant Women in Sao Tome and Principe: A Cross-Sectional Study by Alexandra Vasconcelos, Swasilanne Sousa, Nelson Bandeira, Marta Alves, Ana Luísa Papoila, Filomena Pereira, Maria Céu Machado

“…Ascaris lumbricoides (90.9%) was the most predominant parasite species identified followed by Trichuris trichiura (13.8%). …”
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Adaptation of an additively manufactured reactor concept for catalytic methanation with in-situ tar co-reforming of biogenic syngas by Jakob Müller, Alexander Feldner, Simon Markthaler, Peter Treiber, Jürgen Karl

“…A temperature hot spot near the inlet provides the necessary conditions (high temperature, a suitable catalyst and sufficient residence time) for the reforming of tar species, that are present in the syngas. Two reactor concepts are proposed. …”
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