Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways by Liang Zhu, Yanchi Bi, Ting Liang, Po Zhang, Xiao Xiao, Tengbo Yu

“…Results Network pharmacology has revealed that GK regulates OA via several key pathways, especially NF-κB, HIF-1, PI3K-AKT, and substances like reactive oxygen species. In vitro experiments showed GK effectively reverses oxidative stress damage from TBHP, inhibits inflammatory factor release, and protects Extracellular matrix (ECM) from degradation. …”
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Liability issues for environmental damage caused by military aggression of a terrorist country by I. V. Kyrieieva

“…These factors include: a significant area of damage; species diversity of natural resources that were damaged (soils, subsoil, water bodies, atmospheric air, flora and fauna, territories and objects of the nature reserve fund); the connection of natural resources, which contributes to the spread of negative effects on the environment; the international nature of environmental damage; the long-term consequences of environmental damage; the fact that it is impossible for state authorities and civil society activists to record the full extent of the negative environmental impact of hostilities due to the existing danger. …”
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Novel Bat‐Monitoring Dataset Reveals Targeted Foraging With Agricultural and Pest Control Implications by Brian Lee, Samantha Sambado, D. Nākoa Farrant, Anna Boser, Kacie Ring, David Hyon, Ashley E. Larsen, Andrew J. MacDonald

“…ABSTRACT Quantifying ecosystem services provided by mobile species like insectivorous bats remains a challenge, particularly in understanding where and how these services vary over space and time. …”
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Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis by Caicai Lin, Shuangshuang Zheng, Kui Liu, Ru Yu, Peiyan Guan, Baigeng Hu, Lingling Jiang, Mengyu Su, Guodong Hu, Qingshuai Chen, Xia Zhang

“…Predicted target genes of these miRNAs are involved in calcium channel signaling, osmotic regulation, plant hormone signaling, and reactive oxygen species clearance. Our findings provide valuable insights for the identification and screening of salt-tolerant potato germplasms. …”
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Transcript Profiles of Stria Vascularis in Models of Waardenburg Syndrome by Linjun Chen, Lin Wang, Lei Chen, Fangyuan Wang, Fei Ji, Wei Sun, Hui Zhao, Weiju Han, Shiming Yang

“…Vascular-related and ion channel-related genes in the stria vascularis were also shown significantly difference between the two species. The expression of Col2a1, Col3a1, Col11a1, and Col11a2 genes were higher, and the expression of Col8a2, Cd34, and Ncam genes were lower in the porcine models compared to mouse models. …”
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Drug Clues for the Treatment of Fungal Catheter-Related Bloodstream Infection With Antifungal Lock Therapy by Li X, Yu B, Li H, Liu Z, Fu X, Jiao P, Wang L

“…Shandong First Medical University @ Shandong Academy of Medical Sciences, Jinan, 250117, People’s Republic of ChinaCorrespondence: Ping Jiao; Lei Wang, Email jiaopingonlyone@163.com; wanglei1118@sdfmu.edu.cnBackground: Biofilm formation often represents significant challenges in managing of bloodstream infections associated with catheter use.Objective: Antimicrobial lock therapy serves as an adjunctive treatment for catheter-related infections, effectively eradicating or inhibiting biofilm growth.Methods: This review synthesizes the current knowledge on antifungal lock therapy (ALT) targeting clinically common fungi, primarily Candida species, based on both in vitro and in vivo studies (animals and patients) from the past decade.Results: Amphotericin B (AmB) and echinocandins are identified as the most promising antifungal agents for ALT. …”
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Sarco(endo)plasmic Reticulum Ca2+-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene by Angel Zarain-Herzberg, Georgina Alvarez-Fernandez

“…The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species. It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE). …”
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Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropath... by Chi-Heung Cho, Min-Gyeong Kim, Bomi Ryu, Sang-Hoon Lee

“…We evaluated its anti-glycation ability, intracellular reactive oxygen species scavenging activity, inhibitory effect on the accumulation of intracellular MGO/MGO-derived advanced glycation end products (AGE), and regulation of downstream signaling pathways related to the AGE–receptor for AGEs (RAGE) interaction. …”
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A Validated Reverse Phase HPLC Analytical Method for Quantitation of Glycoalkaloids in Solanum lycocarpum and Its Extracts by Renata Fabiane Jorge Tiossi, Mariza Abreu Miranda, João Paulo Barreto de Sousa, Fabíola Silva Garcia Praça, Maria Vitória Lopes Badra Bentley, James Dewey McChesney, Jairo Kenupp Bastos

“…Solanum lycocarpum (Solanaceae) is native to the Brazilian Cerrado. Fruits of this species contain the glycoalkaloids solasonine (SN) and solamargine (SM), which display antiparasitic and anticancer properties. …”
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Loss of flavonoids homeostasis leads to pistillody in sua-CMS of Nicotiana tabacum by Jie Xu, Zhuo Wei, Jugou Liao, Keliang Tao, Junpeng Zhang, Yu Jiang, Yongzhi Niu, Yunye Zheng, Limeng Zhang, Xuemei Wei

“…Chemical fluorescence staining assay showed that reactive oxygen species (ROS) levels were higher in the pistil-like structure of sua-CMS. …”
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The Role of Sulfur Emission from the Petroleum Industry on Ultrafine Particle Number Concentration in Singapore by Suyi Hou, Weihan Li, Liudongqing Yang, Guorong Chen, Yilin Zhang, Mikinori Kuwata

“…The enhancements in CH4 from its background level (ΔCH4) and SO2 had a quasi-inverse relationship, as the major emission sources of these two chemical species were different. The particle number concentration (dp > 50 nm) correlated with the enhancements in CO concentration (ΔCO) for CH4-dominant air masses, suggesting that incomplete combustion processes, such as traffic emission, are important for the size range. …”
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Cryopreservation of epididymal semen of domestic cat by S. Ya. Amstislavsky, E. Yu. Brusentsev, V. I. Mokrousova, E. A. Kizilova, V. V. Kozhevnikova, V. A. Naprimerov, I. N. Rozhkova

“…Domestic cat (Felis silvestris catus) is used as a model species for developing effective methods of wild felids’ semen cryopreservation. …”
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CFD modelling and simulation of anaerobic digestion reactors for energy generation from organic wastes: A comprehensive review by Muhammad Usman Farid, Indiana A. Olbert, Andreas Bück, Abdul Ghafoor, Guangxue Wu

“…Computational fluid dynamics (CFD) is an applied mathematical tool which helps to understand and predict the fluid dynamics, heat flow as well as species transport in different domains. This approach contributes to minimize the experimental costs while optimizing the reactor configurations in less time. …”
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In Vitro Cadmium-Induced Alterations in Growth and Oxidative Metabolism of Upland Cotton (Gossypium hirsutum L.) by M. K. Daud, Lei Mei, Ullah Najeeb, Muhammad Azim Khan, Farah Deeba, Irum Raza, Aliya Batool, S. J. Zhu

“…From this experiment, it can be concluded that lipid peroxidation as well as reactive oxygen species (ROS) production was relatively higher as has been revealed by higher MDA contents and greater SOD, CAT activities.…”
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Maximizing zearalenone removal: Unveiling the superior efficiency of pre-treated carbon in adsorption and photocatalysis by J.C. Gómez-Vilchis, G. García-Rosales, L.C. Longoria-Gándara, E.O. Pérez-Gómez, D. Tenorio-Castilleros

“…Zearalenone (ZEN) is a mycotoxin produced by Fusarium species, commonly found in food, feed, and water bodies. …”
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Comparative Evaluation of Bandage Contact Lenses and Eye Patching after Bilateral Cataract Surgery by Dalan Jing, Aihua Deng, Hongmei Wang, Yilin Chou, Xiaodan Jiang, Zhenxiang Chen, Xuemin Li, Tingyi Wen

“…Patient satisfaction was determined on Day 1. Moreover, bacterial species in the conjunctival sac, meibomian gland secretions, and BCLs were subsequently identified using 16S rRNA gene sequencing. …”
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Nanodrug‐Engineered Exosomes Achieve a Jointly Dual‐Pathway Inhibition on Cuproptosis by Hanxiao Sun, Yang Zou, Zhengtai Chen, Yan He, Kai Ye, Huan Liu, Lihong Qiu, Yufan Zhang, Yuexue Mai, Xinghong Chen, Zhengwei Mao, Wei Wang, Chenggang Yi

“…This study verifies the presence of cuproptosis in skin wound beds and reactive oxygen species‐induced cells model. To address the two pathways leading to cell cuproptosis, a nanodrug‐engineered exosomes is proposed. …”
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L-Arginine Supplementation in Type II Diabetic Rats Preserves Renal Function and Improves Insulin Sensitivity by Altering the Nitric Oxide Pathway by Taylor Claybaugh, Sarah Decker, Kelly McCall, Yuriy Slyvka, Jerrod Steimle, Aaron Wood, Megan Schaefer, Jean Thuma, Sharon Inman

“…This would impede the formation of reactive oxygen species which contributes to cell damage and death. …”
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Similarities and differences in physiological adaptation to cadmium interactions with nitrogen levels between two aquatic iris life forms in urban wetlands by Zhenzuo Lei, Yuan Jiang, Yanqiong Meng, Yiyong Li, Yucong Li, Tao Hu, Yanjun Ma

“…These findings suggest that evergreen and deciduous irises employ distinct adaptive strategies to Cd toxicity; evergreen irises mitigate oxidative stress through enhanced reactive oxygen species (ROS) scavenging, whereas deciduous irises dilute Cd toxicity by increasing biomass. …”
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Investigating the Adsorption and Corrosion Protection Efficacy and Mechanism of <i>Marjoram</i> Extract on Mild Steel in HCl Medium by Malika Sabiha, Younes Kerroum, Maha El Hawary, Maria Boudalia, Abdelkbir Bellaouchou, Othmane Hammani, Hatem M. A. Amin

“…Importantly, SEM and EDX analyses suggested the formation of a protective layer of the extract onto the steel surface, which shields the surface from corrosive species. This is owed to the functional group-rich phytochemicals of <i>OML</i>. …”
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