Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway by Yachen Si, Lulu Liu, Yinyin Zhang, Hongxia Li, Tingting Zhao, Su Liu, Xuejun Sun, Jin Cheng, Hongtao Lu

“…In addition, the increased level of reactive oxygen species (ROS) and expressions of inflammatory cytokines (TNF-α and IL-1β) and pro-apoptotic factors (Bad, Bax, Caspase3, and CytC) induced by APAP were downregulated with MgH2 treatment. …”
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Risks to human and animal health from the presence of bromide in food and feed by EFSA Scientific Committee, Susanne Hougaard Bennekou, Ana Allende, Angela Bearth, Josep Casacuberta, Laurence Castle, Tamara Coja, Amélie Crépet, Thorhallur Halldorsson, Laurentius (Ron) Hoogenboom, Helle Knutsen, Konstantinos Koutsoumanis, Claude Lambré, Søren Nielsen, Dominique Turck, Antonio Vicent Civera, Roberto Villa, Holger Zorn, Vasileios Bampidis, Jacqueline Castenmiller, Marie‐Christine Chagnon, Bruce Cottrill, Keyvin Darney, Jürgen Gropp, Secundino Lopez Puente, Martin Rose, Marco Vinceti, Maria Bastaki, Petra Gergelová, Luna Greco, Matteo Lorenzo Innocenti, Judit Janossy, Anna Lanzoni, Andrea Terron, Diane Benford

“…Therefore, the reference point of 40 mg/kg bw per day was extrapolated to maximum safe concentrations of bromide in complete feed for other animal species. Bromide can transfer from feed to food of animal origin, but, from the limited data, it was not possible to quantify the transfer rate. …”
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M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury by Qiong Jiang, Xuehai Chen, Kezeng Gong, Zhe Xu, Lianglong Chen, Feilong Zhang

“…The generation of reactive oxygen species (ROS) and the levels of superoxide dismutase (SOD2), mitochondrial transcription factor (TFAM) and cytochrome c oxidase I (COXI) were detected to assess the oxidative stress and mitochondrial biogenesis. …”
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Intermittent Vibration Induces Sleep via an Allatostatin A‐GABA Signaling Pathway and Provides Broad Benefits in Alzheimer's Disease Models by Yang Mou, Yan Zhang, Yuxian Zheng, Guang He, Zhi‐Xiang Xu, Xiao Xiao, Yong Ping

“…Abstract While animals across species typically experience suppressed consciousness and an increased arousal threshold during sleep, the responsiveness to specific sensory inputs persists. …”
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Climate of origin influences how a herbivorous mite responds to drought-stressed host plants by Migeon, Alain, Auger, Philippe, Fossati-Gaschignard, Odile, Hufbauer, Ruth A, Miranda, Maëva, Zriki, Ghais, Navajas, Maria

“…However, it is unclear how much responses to drought stress differ among populations of herbivore species. Here, we evaluate variability among populations of a major agricultural pest, the two spotted spider mite, Tetranychus urticae, in response to drought stress. …”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…The genus Scedosporium (Microascaceae) includes fungi with high tolerance to environmental pollution, whilst some species can be considered major human pathogens, such as Scedosporium apiospermum and Scedosporium boydii. …”
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Molecular Detection of Coxiella burnetii in Ticks Isolated from Domestic Animals in Slaughterhouses and Farms, Shahr-E-Rey, Tehran, Iran by Pedram Talaie, Maryam Tavassoli, Ehsan Mostafavi, Zakiyeh Telmadarraiy, Mahdi Rohani, Saber Esmaeili, Mohammad Mehdi Sedaghat

“…All 77 ticks were pooled by species, and C. burnetii was found in 22.08% (n= 17). …”
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Rapid Identification of Pork Adulterated in the Beef and Mutton by Infrared Spectroscopy by Ling Yang, Ting Wu, Yun Liu, Juan Zou, Yunmao Huang, Sarath Babu V., Li Lin

“…Pork meat is the principal adulterated species of beef and mutton. The conventional detection methods have their own limitations; therefore, we sought to develop an efficient and economical identification method using an infrared spectroscopy technique for meat. …”
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Does water quality matter? Foraging activity of Daubenton’s bat (Myotis daubentonii) over three lakes with different trophy by Małgorzata Strzałka, Katarzyna Kozakiewicz, Postawa Tomasz

“…Our results indicate that the differences in the foraging activity of the bats in the present study do not depend on the trophic status of the lake and are linked directly to opportunistic foraging strategy of the species. The higher foraging activity recorded over the small dystrophic lake may be explained by the isolation of this lake from adverse weather conditions (e.g. wind). …”
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Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells by Franciele Hinterholz Knebel, Renata Chaves Albuquerque, Renato Ramos Massaro, Silvya Stuchi Maria-Engler, Ana Campa

“…These findings agree with the effect triggered by rSAA on matrix metalloproteinases (MMPs) activities measured in a gelatinolytic assay. rSAA inhibited activity of both MMPs in A172 cells while increasing them in T98G cells. rSAA also affected the production of compounds present in the tumor microenvironment that orchestrate tumor progression, such as IL-8, the production of reactive oxygen species (ROS) and nitric oxide (NO). We also observed that both lines expressed all three of the isoforms of SAA: SAA1, SAA2, and SAA4. …”
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Concordant Signal of Genetic Variation Across Marker Densities in the Desert Annual Chylismia brevipes Is Linked With Timing of Winter Precipitation by Daniel F. Shryock, Nila Lê, Lesley A. DeFalco, Todd C. Esque

“…Paired with our finding that habitat resistance best explained genetic divergence, our results suggest that isolation of populations within environmentally similar habitats—and subsequent local adaption along gradients parallel to these habitats—drive genome‐wide divergence in this species. Moreover, strong genetic associations with winter precipitation timing, along with forecasted shifts in precipitation regime due to midcentury climate change, could impact future population dynamics, habitat distribution, and genetic connectivity for C. brevipes populations within the Mojave Desert.…”
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Informing proactive wildfire management that benefits vulnerable communities and ecological values by L. Mae Lacey, Justin P. Suraci, Caitlin E. Littlefield, Blake S. Busse, Brett G. Dickson

“…For instance, restoration in these refined focal areas would cover 28% greater imperilled species richness, 45% greater water importance and 26% more families falling below the poverty line. …”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…Chronic inflammation induces OS, which in turn promotes the perpetuation of the inflammatory process resulting in the release of numerous molecules which cause cell damage. Reactive oxygen species exert a harmful effect on proteins, lipids, and nucleic acids. …”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

“…Quantification of Oil Red O-stained cells showed that lipid droplets decreased following Cape treatment as well as radical oxygen species formation. Additionally, exposure of ASC to high glucose levels decreased adiponectin and increased proinflammatory cytokines mRNA levels, which were reversed by Cape-mediated increase of insulin sensitivity. …”
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Response of Plant Leaf Traits to Environmental Factors in Climax Communities at Varying Latitudes in Karst Regions by Gang Xie, Yang Wang, Zhifeng Chen, Yangyang Ji, Yao Lu, Yi Liang, Ruiyu Zhou, Juan Tao

“…Additionally, we examined the relationship between functional traits and environmental factors, integrating species characteristics and community structure into our analysis. …”
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Overcoming barriers for investigating nickel-pincer nucleotide cofactor-related enzymes by Jorge L. Nevarez, Aiko Turmo, Santhosh Gatreddi, Swati Gupta, Jian Hu, Robert P. Hausinger

“…Such additional detailed characterization will deepen our understanding of the diverse chemistry catalyzed by the NPN cofactor and potentially uncover novel roles for this organometallic species in microbial metabolism.…”
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Comprehensive Mass Spectrometric Analysis of Snake Fruit: Salak (Salacca zalacca) by Petra Hlásná Čepková, Michal Jágr, Dagmar Janovská, Václav Dvořáček, Anna Kotrbová Kozak, Iva Viehmannová

“…Snake fruit (Salacca zalacca (Gaert.) Voss) is a fruit species traditionally cultivated in Indonesia and other Southeast Asian countries. …”
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Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback by Sylvestre, Florent, Aubin-Horth, Nadia, Bernatchez, Louis

“…Moreover, studying gene expression in species with recently established sex chromosomes can help understand the evolutionary dynamics of gene loss and dosage compensation. …”
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Analysis of the Genomes and Adaptive Traits of <i>Skermanella cutis</i> sp. nov., a Human Skin Isolate, and the Type Strains <i>Skermanella rosea</i> and <i>Skermanella mucosa</i> by Yujin Choi, Munkhtsatsral Ganzorig, Kyoung Lee

“…Phenotypic and chemotaxonomic traits of strain TT6^T were also compared with closely related type strains, confirming its genotypic and phenotypic distinctiveness. The new species, <i>Skermanella cutis</i> sp. nov., is proposed, with TT6^T (=KCTC 82306^T = JCM 34945^T) as the type strain. …”
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Juvenile coat colours in mini-pigs at ICG by S. V. Nikitin, S. P. Knyazev, K. S. Shatokhin, G. M. Goncharenko, V. I. Zaporozhets, V. I. Ermolayev

“…It also has a phenomenological character, but it consideres juvenile colour, which is an integral element of the ontogenetic formation of the suit, wild type agouti pigs of the species Sus scrofa L. However, in ICG mini pigs, in addition to individuals with the suit of the wild type, juvenile colour is a feature of pigs with the black spotted suit. …”
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